Clinical trials: Therapy Effect
Female Infertility
Effect of GH Administration in Poor Responders Undergoing Intracytoplasmic Sperm Injection (ICSI)
Despite the use of various treatment strategies, poor response to ovarian stimulation remains a major clinical challenge with lower chance to obtain sufficient number of oocytes and thus less likely to conceive with high risk of…
- Trial name
- NCT05281341
- Testing
- Growth Hormone
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Alexandria University
Diabetes Mellitus, Hyperlipidemia
The Effect of Extract of Green Tea on Obese Women and Obese Related Hormone Peptides
The aim of this study is to examine the therapeutic effect of green tea extract on obese women and the correlation analysis between traditional Chinese medicine syndrome and obese related hormone peptides.
- Trial name
- NCT02147041
- Testing
- EGCG(Epigallocatechin Gallate)
- Where
- Taiwan
- Volunteers
- 92 people
- Sponsor
- Taipei City Hospital
Healthy Volunteers
Zoliflodacin Bioequivalence and Drug-Drug Interaction Study
this study will be a Phase 1, single-dose, two parallel cohorts, open-label, randomized study in healthy subjects with Cohort 1 as bioequivalence (BE) and food effect study and Cohort 2 as a drug-drug interaction (DDI) study.
- Trial name
- NCT05635305
- Testing
- Zoliflodacin Patheon
- Where
- Germany
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Global Antibiotics Research and Development Partnership
Intraarticular, Ozone
Effect of Intraarticular Ozone, Prolotherapy or Dexmedetomidine in Pain Limitation in Knee Osteoarthritis
This study aimed to compare intraarticular ozone injection, prolotherapy, or dexmedetomidine effectiveness in knee osteoarthritis patients.
- Conditions
- Intraarticular, Ozone, Prolotherapy, Dexmedetomidine
- Trial name
- NCT06909305
- Testing
- Ozone, Dextrose prolotherapy, Dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Healthy
Effect of Multiple BI 1356 Doses of on the Multiple-dose Pharmacokinetics of a Combination of Ethinylestradiol and Levonorgestrel in Healthy Female Premenopausal Subjects
The objective was to investigate the effect of multiple oral doses of 5 mg BI 1356 on the steady-state pharmacokinetics of ethinylestradiol (EE) and levonorgestrel (LNG), the components of Microgynon®
- Trial name
- NCT02175394
- Testing
- Microgynon®, BI 1356
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Relative Bioavailability and Impact of Rabeprazole for PF-07799933, Food-Effect for PF-07799933 and PF-07799544
The purpose of this study is to evaluate the relative bioavailability (rBA) of the Form 2 film-coated tablet of PF-07799933 intended for use in future studies compared to the current Form 1 tablet of PF-07799933 used in Phase 1…
- Trial name
- NCT07563894
- Testing
- PF-07799933 tablets with PF-07799544 fasted, PF-07799933 film-coated tablets with PF-07799544 fasted, PF-07799933 film-coated tablets with PF-07799544 fed
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer
Total Knee Arthroplasty
Effect of Emotional Freedom Technique on Postoperative Pain and Anxiety in Patients Undergoing Total Knee Replacement
The purpose of the present study was to examine the effects of the Emotional Freedom Technique on pain and anxiety in the postoperative period of patients who underwent total knee arthroplasty.
- Trial name
- NCT05541666
- Testing
- Emotional Freedom Technique (EFT)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Ataturk University
Schizophrenia
Effect of Quetiapine on Negative Symptoms and Cognition
The purpose of the study is to investigate the outcome on negative symptoms of schizophrenic patients during therapy with quetiapine or risperidone.
- Trial name
- NCT00305422
- Testing
- Quetiapine fumarate, Risperidone
- Where
- Germany
- Volunteers
- 45 people
- Sponsor
- AstraZeneca
Anesthesia, Intubation; Difficult or Failed
Paratracheal Esophagus Pressure on the Intubation With Pentax Airway Scope
Recently, left paratracheal pressure was introduced as an alternative method to prevent pulmonary aspiration instead of cricoid pressure.
- Conditions
- Anesthesia, Intubation; Difficult or Failed, Cricoid Pressure, Pulmonary Aspiration During Anesthetic Induction
- Trial name
- NCT04135651
- Testing
- Paratracheal pressure, Cricoid pressure
- Where
- South Korea
- Volunteers
- 94 people
- Sponsor
- Ajou University School of Medicine
Virtual Reality Based Therapy, Anodal tDCS
Combining tDCS With VR-based Motor Training in Stroke
Stroke represents one of the main causes of adult disability and will be one of the main contributors to the burden of disease in 2030.
- Conditions
- Virtual Reality Based Therapy, Anodal tDCS, Occupational Therapy, Sham tDCS
- Trial name
- NCT03144102
- Testing
- Virtual Reality-based therapy for upper-limbs motor rehabilitation, Anodal transcranial direct-current stimulation (tDCS), Occupational Therapy for upper-limbs motor rehabilitation
- Where
- Spain
- Volunteers
- 36 people
- Sponsor
- Universitat Pompeu Fabra
Horizontal Strabismus With High AC/A Ratio
The Effect of Slanted Recession of Horizontal Muscle on Horizontal Strabismus With Abnormal Accommodative Convergence /Accommodation Ratio (AC/A)
Different methods was tried to treat high AC/A strabismus cases;such as prescription of bifocal glasses in esotropia,recession of horizontal muscles with posterior fixation sutures,more recession than needed for far…
- Trial name
- NCT03555045
- Testing
- conducting the slanted recession technique on the superior and inferior poles, conducting the augmented recession technique on the muscle
- Where
- Iran
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shahid Beheshti University of Medical Sciences
Irritable Bowel Syndrome With Diarrhea
Ibodutant for Relief of Irritable Bowel Syndrome With Diarrhoea (IBS-D)
Irritable Bowel Syndrome with diarrhoea (IBS-D) is a functional gastrointestinal disorder characterised by chronic or recurrent abdominal pain or discomfort and diarrhoea.
- Trial name
- IRIS-2 (NCT01303224)
- Testing
- Ibodutant
- Where
- 71 sites in Bulgaria, Czechia and 6 more
- Volunteers
- 565 people
- Sponsor
- Menarini Group
Atherosclerosis, HIV Infections
Rosiglitazone (Avandia®) Treatment in HIV: Its Effect on Blood Vessels
This trial will study the effect of rosiglitazone on the progression of atherosclerosis (hardening of blood vessels) through improvements of the sugar and fat metabolism (body buildup, breakdown and excretion of sugar and fat).
- Trial name
- NCT00143624
- Testing
- Rosiglitazone maleate
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- University of British Columbia
Hypothermia, Shivering
Efficacy of IV Fluid Warmer for the Prevention of Hypothermia
This study focuses on the importance of the maintenance of body temperature during the surgeries. This study involves the comparison of 2 groups, one receiving warm fluids while the other group receiving room temperature fluids…
- Trial name
- NCT07192224
- Testing
- Hypothermia, Hotline
- Where
- Pakistan
- Volunteers
- 84 people
- Sponsor
- Shaukat Khanum Memorial Cancer Hospital & Research Centre
Carpal Tunnel Syndrome
In Patients With Carpal Tunnel Syndrome, Median Nerve Conduction is Evaluated After Moving the Wrist Bones
The goal of this clinical trial is to analyze the immediate effect of manual mobilization techniques of the carpal bones on the median nerve, in patients with carpal tunnel syndrome.
- Trial name
- NCT06399380
- Testing
- Manual mobilization of the carpal bones.
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Universidad de Zaragoza
Chronic Hepatitis b
Effect of Serum Vitamin D Level on the Efficacy of Peg-interferon Treatment in CHB
In recent years, vitamin D (VD) has received much attention in the fields of host immune regulation, inflammation, fibrosis, cell proliferation and differentiation and tumor. VD works by binding to the vitamin D receptor (VDR).
- Trial name
- NCT05753280
- Testing
- Vitamin D
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Third Affiliated Hospital, Sun Yat-Sen University
Upper Aerodigestive Tract Cancer, Head and Neck Cancer
Effect of Physical Activity Program on Sedentary of Patients With Upper Aerodigestive Tract Cancer
APAORL2 study aims to evaluate the efficacy of a physical activity program on the sedentary and physical activity level during the 18-month program.
- Trial name
- APAORL2 (NCT06184880)
- Testing
- behavioral, Sedentary
- Where
- France
- Volunteers
- 96 people
- Sponsor
- Centre Hospitalier de Valence
Malignant Melanoma
A Study of the Effect of Food on the Pharmacokinetics of Single Dose RO5185426 And the Safety And Efficacy of Continuous Administration in Patients With BRAF V600E Mutation-Positive Metastatic Melanoma
This randomized, open-label, two period crossover study will evaluate the effect of food on the pharmacokinetics of a single dose of RO5185426 and the efficacy and safety of continuous administration in patients with BRAF V600E…
- Trial name
- NCT01264380
- Testing
- RO5185426
- Where
- 10 sites in United States
- Volunteers
- 16 people
- Sponsor
- Hoffmann-La Roche
MCNS, Minimal Change Nephrotic Syndrome (MCNS)
A Study to Evaluate the Effect of Tacrolimus and Corticosteroid Combination Therapy in Patients With Minimal Change Nephrotic Syndrome
To compare the therapeutic effect of tacrolimus in combination with low-dose corticosteroid with high-dose corticosteroid alone in patients with minimal-change nephrotic syndrome.
- Trial name
- T-OPTIMUM (NCT01763580)
- Testing
- Tacrolimus, Prednisolone
- Where
- South Korea
- Volunteers
- 144 people
- Sponsor
- Astellas Pharma Korea, Inc.
Severe Acute Pancreatitis
Effect of Epidural Anesthesia on Pancreatic Perfusion and Clinical Outcome in Patients With Severe Acute Pancreatitis
The aim of the study is to evaluate the safety, the potential beneficial effect of epidural anesthesia on pancreatic perfusion and clinical outcome of patients with severe acute pancreatitis.
- Trial name
- NCT01607996
- Testing
- Epidural anesthesia, Patient controlled intravenous analgesia
- Where
- Switzerland
- Volunteers
- 35 people
- Sponsor
- University Hospital, Geneva
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.