Clinical trials: Therapy Effect
This Study Will Evaluate Whether TXA Reduces Pain
Effect of Tranexamic Acid (TXA) Administered Prior to Shoulder Arthroscopy on Postoperative Pain Medication Usage: A Randomized Controlled Trial
To our knowledge, no studies examining the use of TXA after shoulder arthroscopy in an outpatient setting have been published. This study will evaluate whether TXA reduces pain as measured by opioid consumption and a visual…
- Trial name
- NCT06920264
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- St. Louis Joint Replacement Institute
Balance
A Pilot Study to Investigate the Effect of Motor Imagery on Dynamic Balance of Asymptomatic Students
This study intended to investigate the effect of imagining a movement task on dynamic balance of sedentary university students. Two groups with good mental imaging ability were studied; one group receiving instructions on mental…
- Trial name
- NCT03376334
- Testing
- Mental Motor Imagery
- Where
- Malaysia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universiti Tunku Abdul Rahman
Hypertension
Safety and Effect Study of SHR0532 (Drug Code) Tablets in Patients With Mild Hypertension
The study is being conducted to evaluate the safety and efficacy and Pharmacokinetics/Pharmacodynamics of SHR0532 in subjects with mild hypertension for 4 weeks.
- Trial name
- NCT03971929
- Testing
- SHR0532, Hydrochlorothiazide 25 mg
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Jiangsu HengRui Medicine Co., Ltd.
Newborn Infant, Newborn Health
The Effect of Different Positions Given to the Newborn During Delayed Cord Clamping on Physiological Indicators and Comfort
During intrauterine life, the fetus is connected to the mother via the placenta; with birth, the extrauterine adaptation process begins.
- Conditions
- Newborn Infant, Newborn Health, Delayed Cord Clamping
- Trial name
- Cord Clamping (NCT07719751)
- Testing
- Prone position, Left side lying position
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Mersin University
Postpartum Period
Effects of Pilates and Moderate-Intensity Aerobic Exercise on Postpartum Weight Loss and Body Composition
After childbirth, many women experience difficulty losing pregnancy-related weight, which can affect their health, self-esteem, and physical activity.
- Trial name
- NCT07642245
- Testing
- Pilates, Aerobic Exercise
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Obesity Prevention, Microbiome Analysis
Effect of Agricultural Practices on Crops, Gut Microbiome, and Human Health
The human gut microbiome plays a regulatory role in host health, and is involved in metabolic, immune, and neurological processes.
- Trial name
- MITA (NCT07165145)
- Testing
- Organic Fruits and Vegetables, Conventional Fruits and Vegetables
- Where
- Netherlands
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC)
Heart Failure
Effect of Physical Training Combined Cardiac Resynchronization Therapy in Heart Failure Patients
The investigators hypothesis that exercise training would potentiate the effects of cardiac resynchronization therapy in heart failure patients.
- Trial name
- NCT01939795
- Testing
- exercise training and/or CRT
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Language Development
How Parents Can Help Babies Learn to Talk With Picture Books.
The aim of this project is to test whether giving parents advice about book reading is effective in promoting language learning for infants from a range of socio-economic backgrounds.
- Trial name
- NCT02780557
- Testing
- Contingent Reading Intervention, Book Provision Control
- Where
- United Kingdom
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Malignant Glioma
Effect H2 Water on QoL of Patients Receiving Radiotherapy for High Grade Gliomas.
This is a pilot randomized control trial (RCT) to explore the effects of hydrogen rich water on quality of life in patients with high grade gliomas, receiving focal radiation therapy to the brain concurrent with chemotherapy with…
- Trial name
- NCT04175301
- Testing
- Hydrogen
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stony Brook University
Ambulation Difficulty
Effect of Dexmedetomidine on Sevoflurane Requirements and Emergence Agitation in Children Undergoing Ambulatory Surgery
Although the aetiology of emergence agitation (EA) derives from multiple factors, it is a frequent side effect of sevoflurane anaesthesia in children.
- Trial name
- NCT01691001
- Testing
- Dexmedetomidine, normal saline
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Yonsei University
Asthma
Effect Of Virtual Reality On Pulmonary Function And Anxiety Levels In Asthmatic Patients
The Purpose of the Study This study will be conducted to determine the effect of virtual reality on pulmonary function and anxiety levels in moderate to severe asthmatic patients.
- Trial name
- NCT07141212
- Testing
- Virtual reality glass, Buteyko Breathing
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- October 6 University
Mechanical Ventilation With Oral Intubation
Effect of Body Position Changes on Endotracheal Tube Cuff Pressure in Ventilated Critically Ill Patients
The endotracheal tube secures free airway in patients undergoing surgical procedures or mechanical ventilation. The extraluminal airway needs to be sealed by a cuff. The cuff needs to be adequately inflated with air.
- Trial name
- CP (NCT01757912)
- Testing
- cuff pressure
- Where
- Belgium
- Volunteers
- 12 people
- Sponsor
- University Hospital, Ghent
Coronary Artery Disease, Myocardial Infarction
WENBIT - Western Norway B Vitamin Intervention Trial
PURPOSE OF STUDY Observational studies have demonstrated that elevated levels of plasma total homocysteine is a risk factor for cardiovascular disease.
- Conditions
- Coronary Artery Disease, Myocardial Infarction, Cerebrovascular Stroke
- Trial name
- WENBIT (NCT00354081)
- Testing
- folic acid, vitamin B12 (cyanocobalamin), vitamin B6 (pyridoxine), folic acid, vitamin B12 (cyanocobalamin), vitamin B6 (pyridoxine)
- Where
- 2 sites in Norway
- Volunteers
- 3,096 people
- Sponsor
- Haukeland University Hospital
Low Back Pain
Aromatherapy Massage in Chronic Low Back Pain
The aim was to investigate the effectiveness of adding aromatherapy massage with a mixture of lavender and orange oil to conventional physical therapy in individuals with chronic nonspecific low back pain on pain, central…
- Trial name
- NCT07578181
- Testing
- Conventional Physiotherapy, Aromatherapy Massage + Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Kirsehir Ahi Evran Universitesi
Growth Hormone Deficiency
Growth Hormone's Effect on the Cardiovascular System
To evaluate specific markers of cardiovascular risk before and after growth hormone replacement therapy in a population of growth hormone deficient adults, as compared to an age, gender, and BMI-matched healthy population.
- Trial name
- NCT00397319
- Testing
- Growth Hormone
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Healthy
A Study of RAY1225 at Different Injection Sites in Participants With Different Body Sizes
The purpose of this study is to compare the amount of RAY1225 that gets into the blood stream and how long it takes the body to get rid of it, when injected under the skin of the upper arm and thigh compared to the abdomen.
- Trial name
- NCT06577428
- Testing
- RAY1225
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Guangdong Raynovent Biotech Co., Ltd
Postoperative Delirium, Postoperative Recovery in Elderly Patients
Recovery After Upper Extrimety Surgery
The goal of this randomized clinical trial is to determine whether Bispectral Index (BIS)-guided general anesthesia improves postoperative cognitive recovery and overall quality of recovery in adults undergoing elective hand or…
- Conditions
- Postoperative Delirium, Postoperative Recovery in Elderly Patients, Postoperative Cognitive Dysfunction (POCD)
- Trial name
- Recovery (NCT07714928)
- Testing
- BIS-Guided General Anesthesia, Clinically Guided General Anesthesia
- Where
- Sweden
- Volunteers
- 112 people
- Sponsor
- Region Örebro County
Healthy Adult Females
Postprandial Triglyceride Concentrations Across Menstrual Cycle Phases
The goal of this clinical trial is to investigate the effect of menstrual cycle phases on postprandial triglyceride concentrations in healthy young female adults.
- Trial name
- NCT07459465
- Testing
- Early Follicular Phase, Mid-Luteal Phase
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Breast Reconstruction, Neurotization
Effect of Neurotization on QoL and Sensory Restoration
This is a single-site, randomized, double-blinded trial to assess whether neurotization following autologous breast reconstruction in patients with breast cancer increases quality of life and sensation in the breast compared to…
- Trial name
- NCT05206565
- Testing
- Neurotization - Autologous Reconstruction with DIEP/TRAM
- Sponsor
- University of Wisconsin, Madison
Obesity, Leptin Deficiency
Effect of Triticum Aestivum on Appetite, Ghrelin, Leptin, Adiponectin Hormonal Axis in Patients With Obesity
Obesity represents one of the major health problems worldwide; it is clear that current approaches to address obesity are largely unsuccessful.
- Conditions
- Obesity, Leptin Deficiency, Ghrelin, Adiponectin
- Trial name
- NCT06496100
- Testing
- Triticum Aestivum
- Where
- Mexico
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
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