Clinical trials: Therapy Effect
Healthy Adult, Cardiac Output
Effect of Systematic and Sequential Leg Elevation on Cardiac Output in Healthy Volunteers
Passive leg raising (PLR) transiently increases venous return and cardiac preload and is commonly used to predict fluid responsiveness in critically ill patients.
- Conditions
- Healthy Adult, Cardiac Output, Hemodynamic, Passive Leg Raising
- Trial name
- SYSLE-1 (NCT07860515)
- Testing
- Passive Leg Raising, Non-Invasive Ventilation
- Where
- France
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Pregnancy Complications
Effect of Combined Program of Electro Acupuncture With Exercise on Symphysis Pubis Dysfunction During Pregnancy
Study's Objective: this study aimed to discover the effect of combining electroacupuncture with therapeutic exercises on of symphysis pubis dysfunction during pregnancy.A prospective randomized controlled trial that compared 2…
- Trial name
- NCT07719335
- Testing
- Electro-acupuncture Technique and Stabilizing Exercises
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Delirium
Using Eye Mask and Earplugs on Prevention of Delirium
This research is planned as a randomized controlled experimental study to examine the effect of using eye mask and earplugs in preventing delirium with evidence-based nonpharmacological nursing interventions in intensive care…
- Trial name
- NCT05000476
- Testing
- eye mask and earplugs, Nurse Education and Environmental Regulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Baskent University
Mother Fetus Relations, Health Behavior
Examining the Effect of Breastfeeding Education Given to Mothers Based on Postpartum Awareness Practices on Breast Milk and Cortisol Hormone at the Newborn Circadian Level
In addition to being an easily accessible and ready-made food for babies in the first years of life, breast milk plays a major role in transmitting information about the time of day to newborn babies and therefore in the…
- Trial name
- NCT06240676
- Testing
- AWARENESS-BASED COGNITIVE THERAPY
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Kafkas University
Healthy
Drug Interaction Study To Investigate The Potential Effect Of Proton Pump Inhibitor On The Pharmacokinetics Of Palbociclib (PD-0332991)
Fixed sequence, 2-period crossover study to compare the pharmacokinetic profiles of Palbociclib in absence and presence of prior administration of proton pump inhibitor Rabeprazole.
- Trial name
- NCT01918176
- Testing
- Palbociclib alone, Palbociclib + Rabeprazole
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Pfizer
Spermatozoa and Embryos
Effect of the Number of Inseminated Spermatozoa on Subsequent Human Embryonic Development in Vitro
In order to reach fertilization in the context of IVF, the presence of high concentrations of spermatozoa is associated with a higher degree of sperm metabolism and a higher concentration of sperm degradation products, which may…
- Trial name
- NCT00710476
- Testing
- Insemination
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Urinary Incontinence
the Effect of a New Type of Pelvic Floor Rehabilitation Device PHENIX U4+ on the Treatment of Urinary Incontinence
Enrolled patients with urinary incontinence in Peking University People's Hospital, Wuhan People's Hospital, Zhongshan People's Hospital, and Jiangsu Maternity and Child Health Hospital in the Department of Gynecology, and…
- Trial name
- NCT05202717
- Testing
- PHENIX U4+, Traditional pelvic floor treatment instrument
- Where
- China
- Volunteers
- 202 people
- Sponsor
- Peking University People's Hospital
Therapeutic Plasma Exchange
TPE in Rennes Hospital
To assess the indications, tolerance and side effects of therapeutic plasma exchange (TPE) performed at a University Hospital over 8 years
- Trial name
- COMPLASMA (NCT03888417)
- Testing
- Therapeutic plasma exchange (TPE)
- Where
- France
- Volunteers
- 190 people
- Sponsor
- Rennes University Hospital
Repetitive Negative Thinking, Neurofeedback
Effect of Mindfulness-based Neurofeedback for Adolescents With Elevated Repetitive Negative Thinking
This study will test the hypotheses that adolescent with repetitive negative thinking who at at-risk for serious mental illness will show greater default mode network (DMN) connectivity than healthy controls, at-risk adolescents…
- Trial name
- CHARMS (NCT07055217)
- Testing
- Mindfulness Training, Mindfulness-based Neurofeedback (Real mbNF)
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Postoperative Pain, Tonsillectomy
Sphenopalatine Ganglion Block for Pain Relief After Pediatric Adenotonsillectomy
The aim of this clinical trial is to discover whether sphenopalatine ganglion block (SPGB) reduces postoperative pain in children aged 2 to 13 years undergoing tonsil surgery (with or without adenoid removal).
- Conditions
- Postoperative Pain, Tonsillectomy, Adenotonsillectomy
- Trial name
- SPARK (NCT07793617)
- Testing
- Sphenopalatine ganglion block (Ropivacaine)
- Volunteers
- 145 people
- Sponsor
- Vinícius C Quintão, MD, MSc, PhD
Ventilator Associated Pneumonia (VAP), Evidence Based Practice
Effect of Implementing Evidence-based Practice and Nurse's Behavior Change on Quality of Care in Intensive Care Unit: Focus on Ventilator Associated Pneumonia in a Tertiary Hospital in Bangladesh
Quality of care is crucial for preventing adverse events such as infection in the intensive care units (ICUs). The most common ICU-acquired infections include pneumonia such as ventilator-associated pneumonia (VAP), Central Line…
- Trial name
- EBP in Nursing (NCT06624540)
- Testing
- This is a pre- and post- quasi-experimental study., Education with EBP
- Where
- 2 sites in Bangladesh, Japan
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Airway Management, Airway Complication of Anaesthesia
The Effect of Assistive Airway Equipment on Intubation
In this study, investigators will research the types and incidence rates of airway complications seen in the perioperative period during airway management.
- Trial name
- NCT06596889
- Testing
- Successful airway management
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- Kocaeli City Hospital
Atrial Fibrillation
Effects of Fish Oil on Post Ablation Arrhythmias
To determine if peri-operative treatment with omega-3 fatty acids is associated with a decrease in the incidence of early recurrences of atrial arrhythmias (within 30 days) and an improvement in probability of long-term…
- Trial name
- NCT00791089
- Testing
- LOVAZA Omega 3-acid ethyl esters, LOVAZA
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Michigan
Cerebral Palsy (CP)
Effect of Aquatic Therapy Program on Balance in Children With Spastic Diplegic Cerebral Palsy
1. Evaluate the effect of a structured aquatic therapy programme on static balance in children with spastic diplegic cerebral palsy. 2. Assess the effect of the same programme on dynamic balance in this patient population. 3.
- Trial name
- NCT07669350
- Testing
- aquatic therapy, land exercise program
- Volunteers
- 50 people
- Sponsor
- Delta University for Science and Technology
COVID-19 Respiratory Infection
Role of Vit-D Supplementation on BioNTech, Pfizer Vaccine Side Effect and Immunoglobulin G Response
The goal of this clinical trial study is to investigate the role of anthropometric indices and Vit-D supplementation on BioNTech, Pfizer vaccine side effect and immunoglobulin G response against SARS-CoV-2 in individuals infected…
- Trial name
- NCT05851313
- Testing
- Vitamin-D
- Where
- Iraq
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Sulaimani Polytechnic University
Competitive Swimmer, Beetroot Powder
The Effect of Beetroot Powder on Exercise Performance in Competitive Swimmers
Swimming requires high energy in a short time and involves overcoming water resistance. Besides regular training, swimmers use supplements to enhance performance, correct nutrient deficiencies, and speed recovery.
- Trial name
- NCT07662460
- Testing
- Beetroot Powder
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Halic University
Hypotension
Influence of Preload Dependence on the Effect of Phenylephrine on Cardiac Output
The perioperative hemodynamic management aims to ensure organ perfusion pressure and an oxygen arterial transport adapted to oxygen consumption.
- Trial name
- NCT01730820
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Caen
Sarcopenia
Effect of Integrated Care Involving Peripheral Functional Magnetic Stimulation for Sarcopenia
The goal of this clinical randomized trial is to test whether an integrated care involving peripheral functional magnetic stimulation and nutritional supplement is beneficial in population with age-related sarcopenia, as compared…
- Trial name
- NCT06182020
- Testing
- Peripheral functional magnetic stimulation (ISKRA MEDICAL TESLA Former prestige Magneto therapy), Nutritional supplementation (ENSURE HIGH CALCIUM), Education
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Taiwan University Hospital
Evidence of Cholecystectomy
Effect of Preoperative Oral Carbohydrates on Quality of Recovery
Carbohydrate loading is an important component of enhanced recovery pathways. Preoperative carbohydrate treatments have been widely adopted as part of enhanced recovery after surgery (ERAS) or fast-track surgery protocols.
- Trial name
- laparoscopy (NCT02555020)
- Testing
- Allocated to Carbohydrated group, Allocated to MN NPO group,
- Volunteers
- 153 people
- Sponsor
- Yonsei University
Colon Cancer
Comparison of Limb Size of Transverse Coloplasty Pouch
The aim of the study is the comparison of pouch function with two different sizes of limb of transverse coloplasty pouch after rectal resection and total mesorectal excision.
- Trial name
- NCT01071824
- Testing
- Transverse coloplasty pouch (Long limb), Transverse coloplasty pouch (Short limb)
- Where
- Switzerland
- Volunteers
- 52 people
- Sponsor
- Kantonsspital Liestal
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