Clinical trials: Therapy Effect
Epinephrine Toxicity, Cataract
The Effect of Intracameral Carbachol and Epinephrine on Choroidal Thickness
81 eyes of 81 patients undergoing cataract surgery were included in this prospective interventional study. During cataract surgery, intracameral carbachol was applied to 27 eyes, intracameral epinephrine was administered to 20…
- Conditions
- Epinephrine Toxicity, Cataract, Carbachol Adverse Reaction, Choroid Disease
- Trial name
- NCT05225597
- Testing
- Intracameral administration of epinephrine and carbachol during cataract surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 81 people
- Sponsor
- Ordu University
Non-Alcoholic Fatty Liver Disease
Effect of Omega-3 PUFA Supplementation in NAFLD Patients
The purpose of this study is to determine whether dietary supplementation with omega-3 polyunsaturated fatty acids will decrease the amount of fat in liver.
- Trial name
- NCT00230113
- Testing
- Fish oil, Safflower oil
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Diabetes Mellitus, Type 2
Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose
The purpose of this study is to measure the effect of LY2189265 to increase insulin levels in response to glucose intake.
- Trial name
- NCT01300260
- Testing
- LY2189265, Insulin, Glucose
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Diabete Type 2
Effect of a Healthy Food Voucher on Blood Glucose Control in People With Type 2 Diabetes or Prediabetes
This randomized controlled trial (RCT) will determine if access to a voucher for healthy foods reduces blood sugar levels among people living on a low income who have type 2 diabetes or elevated blood sugar.
- Trial name
- VOUCH4DIABETES (NCT05776420)
- Testing
- Food voucher
- Where
- Canada
- Volunteers
- 390 people
- Sponsor
- Unity Health Toronto
Benign Paroxysmal Positional Vertigo, Balance
Effect of Wii Fit Training in Comparison to Vestibular Rehabilitation Training on Balance in Patients With Benign Paroxysmal Postional Vertigo
THIS STUDY IS A RANDOMIZED CONTROL TRIAL AND THE PURPOSE OF THE STUDY IS TO DETERMINE THE EFFECT OF WIIFIT TRAINING IN COMPARISON TO VESTIBULAR REHAB TRAINING ON BALANCE IN PATIENTS WITH BENIGN PAROXYSMAL POSITIONAL VERTIGO
- Conditions
- Benign Paroxysmal Positional Vertigo, Balance, Vertigo
- Trial name
- NCT06738823
- Testing
- INTERVENTION GROUP : TRAINING WITH WIIFIT, VESTIBULAR REHABILITATION TRAINING
- Where
- Pakistan
- Volunteers
- 38 people
- Sponsor
- Foundation University Islamabad
Intracranial Atherosclerosis ICAS
Moderate Versus Intensive Lipid-lowering for Events in Asymptomatic Intracranial Stenosis
It is designed to compare two different strengths of cholesterol-lowering treatment in patients who have narrowing of blood vessels inside the brain (intracranial atherosclerosis) but do not currently have symptoms such as…
- Trial name
- MILES (NCT07791823)
- Testing
- Lipid Lowering Treatment
- Where
- South Korea
- Volunteers
- 1,626 people
- Sponsor
- Woo-Keun Seo
Acne, Patient Compliance
"A Randomized, Controlled, Evaluator-blinded Pilot Study to Evaluate the Effect of Automated Text Message Reminders on Patient Compliance With Topical Medications and Its Efficacy on Skin Disease Control in Adolescents and Adults With Mild to Moderate Acne"
The purpose of this study is to determine whether an automated electronic reminder system using text messages sent to patient's cell phones will help patients with acne be more compliant with their topical medications and lead to…
- Trial name
- NCT01082523
- Testing
- Text message reminders
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- University of Texas Southwestern Medical Center
Sports Physical Therapy
Hip Abductor Strengthening With Proprioceptive Neuromuscular Facilitation
Objectives: To compare effectiveness of strengthening hip abductors with Proprioceptive Neuromuscular Facilitation (PNF) technique and Range Of Motion (ROM) exercises on core endurance and functional performance in healthy adults…
- Trial name
- NCT05840523
- Testing
- Proprioceptive Neuromuscular Facilitation exercises, The Range Of Motion exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Nurse's Role
Effect of Immunization Education Program on Parental Vaccine Hesitation
Not administering vaccines due to vaccine hesitancy is both a potential public health problem and a difficult and risky situation for healthcare professionals.
- Trial name
- NCT06495359
- Testing
- immunization education program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Bilecik Seyh Edebali Universitesi
Lung Cancer
Impact of Using a GLP1 on Treatment Related Side Effects of Lung Cancer Patients Receiving Lorlatinib
The proposed study seeks to address a critical gap in the management of lorlatinib-induced metabolic derangements, particularly rapid weight gain, which can adversely affect treatment adherence, dosing and ultimately patient…
- Trial name
- NSCLC (NCT07782359)
- Testing
- Tirzepatide
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Schizophrenia
Effect of Sarcosine on Symptomatology, Quality of Life, Oxidative Stress and Glutamatergic Parameters in Schizophrenia
The purpose of study is to determine whether dietary supplement sarcosine is effective in treatment of schizophrenia. The investigators will assess impact of sarcosine on quality of life and sexual functioning.
- Trial name
- PULSAR (NCT01503359)
- Testing
- Sarcosine
- Where
- Poland
- Volunteers
- 70 people
- Sponsor
- Medical University of Lodz
Fibromyalgia
Impact of the Placebo Effect on the Effects of Trancranial Direct Current Stimulation in Fibromyalgia
Fibromyalgia (FM) is a syndrome characterized by generalized musculoskeletal pain, fatigue, non-restorative sleep, cognitive alterations, depressive and neurovegetative symptoms.
- Trial name
- NCT05903079
- Testing
- s-Tdcs
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Acute Myocardial Infarction (AMI)
Stellate Ganglion Morphine Infiltration on Myocardial I/R Injury
The goal of this clinical trial is to investigate whether morphine modulates the functions of the stellate ganglion to reduce myocardial ischemia/reperfusion (I/R) injury in AMI patients.
- Trial name
- tSGM-AMI (NCT07023679)
- Testing
- Morphine
- Where
- 2 sites in China
- Volunteers
- 2,588 people
- Sponsor
- The Second Hospital of Anhui Medical University
Sarcopenia
Combined Effects of Resistance Training and Nutritional Supplements in the Treatment of Sarcopenia
Age-related sarcopenia is associated with increased morbidity, mortality, disability and reduced resistance to metabolic stress.
- Trial name
- NCT00748696
- Testing
- Fortimel Extra®, resistance training, combined treatment
- Where
- France
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Surgery With General Anesthesia
Validation of the Effect of Propofol and Opiates Closed-loop Administration Device During Anesthesia and Sedation
Sleeping medication and analgesia are standard administered during anesthesia. Sleeping medication, Propofol (Diprivan, AstraZeneca), and analgesia, Remifentanil (GlaxoSmithKline), are most frequently used In the University…
- Trial name
- NCT00764855
- Testing
- Automatic administration of propofol and opiates during routine clinical practice
- Where
- Belgium
- Volunteers
- 180 people
- Sponsor
- University Hospital, Ghent
Systemic Sclerosis
Long Term Effect of Buspirone on Esophageal Function and Esophageal Symptoms in Patients With Systematic Sclerosis (SSc)
Esophagus is commonly affected in Systemic Sclerosis (SSc) and esophageal function is compromised in about 75% of patients. Previous studies have shown that buspirone, an orally available 5-HT1A (serotonin 1a receptor agonist)…
- Trial name
- NCT02363478
- Testing
- buspirone
- Where
- Greece
- Volunteers
- 22 people
- Sponsor
- Laikο General Hospital, Athens
Low-dose Radiotherapy, Tumor Microenvironment
Effect of Low-dose Radiotherapy on Tumor Immune Microenvironment in Oligometastases of NSCLC After Immunotherapy
The purpose of this phase Ⅱ trial was to investigate the effect of low-dose radiotherapy (LDRT) on the tumor immune microenvironment (TME) in oligometastasis, oligoprogression, and oligopersistence of non-small cell lung cancer…
- Conditions
- Low-dose Radiotherapy, Tumor Microenvironment, Non-Small Cell Lung Cancer
- Trial name
- NCT06331585
- Testing
- low dose radiotherapy
- Where
- China
- Sponsor
- Hetian District People's Hospital
Atrophy, Muscular, Atrophy, Disuse
Blood Flow Restricted Electrical Stimulation During Immobilisation
Following injury or surgery to a limb, it is often immobilised to allow tissue healing. Short periods of disuse cause loss of muscle size and strength and impaired mechanical properties of tendons, which leads to reduced…
- Trial name
- NCT05093985
- Testing
- Neuromuscular electrical stimulation with blood flow restriction
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- St Mary's University College
Healthy
The Effect of Transcranial Direct Current Stimulation of the Primary Motor and Somatosensory Cortex on Pain Thresholds.
The purpose of this study is to investigate the modulatory effect of a novel tDCS configuration on the pain sensitivity in healthy subjects.
- Trial name
- NCT04658485
- Testing
- Active tDCS
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Acne Scars - Mixed Atrophic and Hypertrophic
Safety and Efficacy Investigation on the Effects of ClearSkin Non-ablative ER:Glass 1540nm Laser Module in the Treatment of Acne Scars.
The ClearSkin module, Er: Glass 1540nm, is largely used in the treatment of acne vulgaris and acne scars. The non-ablative ER:Glass 1540 nm laser deeply penetrates the skin, causing thermal damage to the sebaceous glands…
- Trial name
- NCT06102343
- Testing
- Alma Harmony
- Where
- Portugal
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Alma Lasers
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