Clinical trials: Therapy Effect
Obesity & Overweight
The Effect of Exercise and Tirzepatide on Weight and Health Outcomes (EXER-MED)
This is clinical trials is to evaluate the effect of exercise with weight loss medication compared to weight loss alone. The study will enroll 24 adults from 30-65 years old with overweight or obesity.
- Trial name
- EXER-MED (NCT07298915)
- Testing
- Tirzepatide, Exercise
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Virginia
Test the Efficacy of Antiplatelet Regimes in Acute Stroke
Dose-Dependent Effect of Early Antiplatelet Therapy in Acute Ischemic Stroke
The aim of this study is to evaluate the low-response prevalence of early antiplatelet therapy and to test the influence of different aspirin dosages in patients with acute ischemic strokes (AIS).
- Trial name
- NCT01273935
- Where
- Germany
- Volunteers
- 400 people
- Sponsor
- Ruhr University of Bochum
Hypertension
The Effect of Nitrendipine/Atenolol Combination on Blood Pressure Variability.
1. Study name: The Effect of Nitrendipine/Atenolol Combination on Blood Pressure Variability. 2. Medicine: Nitrendipine/Atenolol; Nitrendipine; Atenolol. 3.
- Trial name
- NCT04931108
- Testing
- Nitrendipine/Atenolol, Nitrendipine, Atenolol
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Cerebral Palsy, Cortical Visual Impairment
Cortical Visual Impairment and Visual Attentiveness
This study will investigate the effect of enhanced visual and cross-modal environments upon the visual attentiveness of multiply handicapped children diagnosed with Cerebral Palsy (CP) and Cortical Visual Impairment (CVI).
- Trial name
- NCT00342108
- Testing
- cross-modal sensory stimulation
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center
Airway Responsiveness
The Effect of Esomeprazole and Fundoplication on Airways
Evaluate the prevalence of bronchial responsiveness (BHR) among patients with gastroesophageal reflux disease (GERD). Investigate correlation between bronchial reactivity and the severity of GERD, and similarly investigate the…
- Trial name
- NCT00994708
- Testing
- esomeprazole
- Where
- Finland
- Sponsor
- Tampere University Hospital
Prostate Cancer, Radiotherapy Side Effect
Hypofractionated Radiotherapy in Prostate Cancer Patients Aged 75 Years or Older.
The majority of all new prostate cancer cases are diagnosed in men aged > 70 years, with the highest incidence in men aged > 90 years.
- Trial name
- NCT04535908
- Testing
- Hypofractionated radiotherapy
- Where
- Austria
- Volunteers
- 23 people
- Sponsor
- Medical University of Graz
Reflux Esophagitis
Incidence of Reflux Esophagitis After Pancreaticoduodenectomy
Reflux esophagitis is a common complication following distal gastrectomy. According to the investigators preliminary data, an Roux-en--Y gastrointestinal reconstruction in pancreaticoduodenectomy is associated with higher rates…
- Trial name
- NCT01311908
- Testing
- Methods of gastrojejunostomy reconstruction
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- National Taiwan University Hospital
Dehydration
Subcutaneous vs Intravenous Hydration on Older Adults
This study will evaluate the risk of adverse effects of intravenous hydration compared to subcutaneous hydration. Half of the patients will receive hydration by the subcutaneous route the other half by the intravenous route.
- Trial name
- SCIV (NCT03710408)
- Testing
- Intravenous hydration, Subcutaneous hydration
- Where
- Denmark
- Volunteers
- 51 people
- Sponsor
- Aalborg University Hospital
Musculoskeletal Pain, Athletic Injuries
Single Focused Shock Wave in the Release od Delayed Onset Muscle Soreness (DOMS)
The study is a single-center, double blinded, randomized controlled trial aimed to investigate the effects of focused extracorporeal shockwave therapy (fESWT) on Delayed Onset Muscle Soreness (DOMS) of the non-dominant biceps…
- Trial name
- NCT02548208
- Testing
- Verum focused extracorporeal shockwave
- Where
- Germany
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Dr. Johannes Fleckenstein
Osteo Arthritis Knee
The Effect of Smart Ring Assisted Physiotherapeutic Intervention After TKR
The goal of this randomized controlled trial is to learn about the effect of a wearable activity tracker assisted physiotherapeutic intervention on the risk of poor patient reported outcome after a primary total knee replacement.
- Trial name
- SmarTKRing (NCT05599776)
- Testing
- Smart ring assisted physiotherapeutic intervention
- Where
- Finland
- Volunteers
- 338 people
- Sponsor
- Coxa, Hospital for Joint Replacement
Chronic Disease, Covid-19 Pandemic
Effect of Hand-Washing Training in Covid-19
This study was conducted in order to inform, the women with chronic disease in rural areas, about hand-washing and nutrition, and to evaluate the efficiency of the training program.
- Trial name
- NCT04957017
- Testing
- Training
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Ersoy University
Diabetes, Diabetes Mellitus, Type 2
The Effect of Liraglutide Compared to Sitagliptin, Both in Combination With Metformin on Glycaemic Control in Subjects With Type 2 Diabetes Mellitus
This trial is conducted in Europe and North America. The aim of this trial is to compare the effect on blood sugar control of liraglutide or sitagliptin, both in combination with metformin, in subjects with type 2 diabetes…
- Trial name
- NCT00700817
- Testing
- liraglutide, sitagliptin, metformin
- Where
- 166 sites in United States, Canada and 13 more
- Volunteers
- 665 people
- Sponsor
- Novo Nordisk A/S
Breast Cancer Survivors
Life Style Modification for Breast Canccer Survivors Using Mobile App-based Human Coaching Program
This study is aimed to investigate whether mobile app-based human coaching program for 6 months is effective for reducing BMI in breast cancer survivors with overweight and obesity.
- Trial name
- NCT05506189
- Testing
- mobile application program with human coach
- Where
- South Korea
- Volunteers
- 130 people
- Sponsor
- National Cancer Center, Korea
Schizophrenia
A Safety, Tolerability, and Pharmacokinetics Study of MK-8189 in Participants With Schizophrenia and in Healthy Participants (MK-8189-007)
This 4-panel study will evaluate the safety, tolerability, pharmacokinetics (PK) and corrected QT interval (QTc) effect of MK-8189 versus placebo, as monotherapy in healthy participants (Panel A) including those of Japanese…
- Trial name
- MDCS (NCT03565068)
- Testing
- MK-8189, Background AAP Therapy
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Vitamin D Deficiency, Chemotherapy Effect
Vitamin D Can Increase Pathological Response of the Breast Cancer Patients Treated With Neoadjuvant Therapy
The aim of the study is to evaluate the relationship between the vitamin D replacement and pathological response in patients undergoing neoadjuvant therapy according to different molecular sub types.
- Conditions
- Vitamin D Deficiency, Chemotherapy Effect, Pathology
- Trial name
- NCT03986268
- Testing
- Vit D
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Florence Nightingale Hospital, Istanbul
Parkinson's Disease
The Effect of Rifampin on the Metabolism of Istradefylline in Healthy Volunteers.
The purpose of this study is to test whether Rifampin affects blood levels of istradefylline in humans. Rifampin could possibly decrease istradefylline levels.
- Trial name
- NCT02174250
- Testing
- Istradefylline 40 mg, Rifampin 300mg BID + istradefylline 40mg Day 8 only
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Kyowa Kirin Co., Ltd.
Women Following Unilateral Mastectomy
Shoulder Exercise Training on Pain, Range of Motion, and Functional Limitations in Women Following Unilateral Mastectomy
Shoulder pain, reduced mobility, and functional limitations are common complications following unilateral mastectomy, often leading to long-term disability and an increased risk of secondary shoulder-hand syndrome
- Trial name
- NCT07478718
- Testing
- Interventions 1. Scapular and Shoulder Exercise Program (Intervention Group) Supervision and Duration • 3 sessions/week • 45-60 minutes per session • Total duration: 8 weeks (24 sessions) • Conducted
- Where
- Jordan
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- South Valley University
Knee Osteoarthritis
Effect of Energy Restriction and Exercise for Knee Osteoarthritis
The investigators are looking at the effects of energy restriction, with or without exercise on markers of inflammation in individuals with knee osteoarthritis.
- Trial name
- NCT05518890
- Testing
- Diet Only, Diet plus Exercise
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Bath
Hypercholesterolemia
Lipid-lowering Effect of Plant Stanol Drink
To determine the effect of investigational products on serum LDL cholesterol.
- Trial name
- NCT01716390
- Testing
- Drink that contains plant stanols
- Where
- Sweden
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Raisio Group
Type 2 Diabetes Mellitus, Cardiovascular Abnormalities
Curcumin for Type 2 Diabetic Patients
There are evidence that there is an association between insulin resistance and prolonged hyperinsulinemia or hyperglycemia in Type 2 diabetic patients.
- Trial name
- NCT01052597
- Testing
- curcumin
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Srinakharinwirot University
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