Clinical trials: Therapy Effect
Periodontitis
Sterify Gel as an Adjunct to Non-Surgical Periodontal Therapy in Periodontitis
This retrospective observational study will evaluate the clinical response to Sterify Gel, a sterile mucoadhesive polymeric hydrogel, when used as an adjunct to non-surgical periodontal therapy in adult patients with stage II…
- Trial name
- Sterify (NCT07672665)
- Volunteers
- 20 people
- Sponsor
- IRCCS San Raffaele
Cardiovascular Disease
High Dose and Low Dose of Atorvastatin in Patients With Unstable Angina and NSTEMI (Non ST Elevation MI)
The aim of this study is to compare the effect of high dose and low dose of Atorvastatin in reduction level of C-reactive protein (CRP) in patients with unstable angina and NSTEMI (Non ST Elevation MI) attending Shahid Mohammadi…
- Trial name
- NCT01306565
- Testing
- Low dose Atorvastatin, High dose atorvastatin
- Where
- Iran
- Volunteers
- 100 people
- Sponsor
- Hormozgan University of Medical Sciences
Hand Massage
The Effect of the Hand Massage A Women Undergoing Brachytherapy
Background Gynecologic cancers are among the ten most common cancers among women. During brachytherapy, women can have pain and situational anxiety due to the treatment.
- Trial name
- NCT05937607
- Testing
- Hand massage
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Celiac Disease in Children
Physical Fitness in Celiac Disease Patients - the Effect of a Gluten Free Diet
Evaluating the effect of Celiac disease (CD) and gluten free diet (GFD) on physical fitness parameters among CD subjects. The CD subjects will be compared to healthy controls.
- Trial name
- NCT04012736
- Where
- Israel
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Clonal Cytopenia of Uncertain Significance, CCUS Clonal Cytopenia of Undetermined Significance
Modulation of Stem Cell Differentiation in Individuals With High Risk Clonal Haematopoiesis
Clonal hematopoiesis (CH) is characterized by the overproduction of blood cells derived from a single hematopoietic stem and progenitor cell (HSPC) harboring certain somatic mutations.
- Conditions
- Clonal Cytopenia of Uncertain Significance, CCUS Clonal Cytopenia of Undetermined Significance, Clonal Hematopoiesis
- Trial name
- MOSAIC (NCT07435636)
- Testing
- Oral Decitabine and Tetrahydrouridine
- Where
- 3 sites in Australia
- Volunteers
- 80 people
- Sponsor
- Clinical Hub for Interventional Research (CHOIR)
Death Anxiety, Occupational Stress
Effect of Expressive Arts Therapy on Death Anxiety in Intensive Care Unit Nurses
This randomized controlled trial aimed to evaluate the effect of expressive arts therapy on death anxiety among intensive care unit nurses.
- Conditions
- Death Anxiety, Occupational Stress, Psychological Distress
- Trial name
- Expressive Art (NCT07462936)
- Testing
- Expressive Arts Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Muskuloskeletal Diseases
The Effect of Telerehabilitation on Pain, Physical and Biopsychosocial Factors in Parent Carers
This study aimed to investigate the effects of asynchronous video-based exercises on pain, disability, anxiety, care burden and quality of life in parent carers of children with special needs.
- Trial name
- NCT06518811
- Testing
- Video-Based Exercise Programme
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ilke KARA
Diabetes, Diabetes Mellitus, Type 2
Effect of Repaglinide and Metformin Combination Tablet or Rosiglitazone and Metformin in Fixed Dose Combination on Blood Glucose Control in Patients With Type 2 Diabetes
This trial is conducted in the United States of America (USA). This trial compares the changes in HbA1c after 26 weeks of repaglinide and metformin fixed dose combination tablet given as twice daily versus three times daily…
- Trial name
- NCT00399711
- Testing
- repaglinide and metformin combination tablet, rosiglitazone and metformin combination tablet
- Where
- 103 sites in United States, Puerto Rico
- Volunteers
- 560 people
- Sponsor
- Novo Nordisk A/S
Hypotension
The Effect of Sevoflurane Versus Isoflurane on Vasopressor Need
Aim of this study is to determine the effect of isoflurane versus sevoflurane on blood pressure and systemic vascular resistance.
- Trial name
- ESIVAN (NCT00922844)
- Testing
- Sevoflurane and isoflurane
- Where
- Netherlands
- Volunteers
- 10 people
- Sponsor
- UMC Utrecht
Breast Cancer, Chemotherapy Effect
The Prediction Model of NAC Response for Breast Cancer Based on The Parametric Dynamics Features.
The main purpose of this study is to develop a computer-aided prediction model for NAC treatment response. Based on the heterogeneity of internal parametric tumor composition commonly observed, this study will utilize the…
- Conditions
- Breast Cancer, Chemotherapy Effect, Diffusion Weighted MRI, PET Imaging
- Trial name
- NCT06370234
- Testing
- Whole body 18F-FDG Positron Emission Tomography
- Volunteers
- 60 people
- Sponsor
- National Taiwan University Hospital
Arterial Pressure, Blood Pressure Determination
Standardized Patients in Arterial Pressure Monitoring Training
This study aims to evaluate and compare the effects of using standardized patients versus static manikins in nursing education for arterial blood pressure monitoring and stabilization training.
- Conditions
- Arterial Pressure, Blood Pressure Determination, Simulation Training, Education, Nursing
- Trial name
- NCT07670364
- Testing
- Arterial Pressure Monitoring Training
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Acute Coronary Syndromes, Acute Myocardial Infarction
Effect of Adjunctive Intracoronary Streptokinase on Late Term Left Ventricular Infarct Size and Volumes in Patients With Acute Myocardial Infarction
The investigators hypothesized that complementary intracoronary streptokinase administration to primary percutaneous intervention in patients with acute myocardial infarction may provide limitation infarct size and improvement in…
- Conditions
- Acute Coronary Syndromes, Acute Myocardial Infarction, Reperfusion Injury
- Trial name
- NCT00627809
- Testing
- Streptokinase, primary percutaneous coronary intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people
- Sponsor
- Istanbul University
Comparison of the Effects of Different Therapies in Geriatric Individuals
Should Dual Task Training or Action Observation Therapy be Used in Geriatric Individuals?
Summary Aging leads to significant declines in both motor skills and cognitive functions. Declines in walking, balance, and general mobility are particularly evident, while declines in cognitive functions such as attention…
- Trial name
- NCT07209709
- Testing
- Conventional exercises with dual task training (cognitive task), Conventional Exercise With Action Observation Therapy, Conventional Exercise (Control Group)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Inonu University
Diabetes, Cervical Myelopathy
Diabetes and Glycosylation in Cervical Spondylosis
The purpose of this study is to determine the relevant significance of diabetes on cervical disc degeneration, and correlate diabetic control (HgbA1C) with disc glycosylation profile in patients undergoing anterior cervical…
- Conditions
- Diabetes, Cervical Myelopathy, Cervical Spondylosis
- Trial name
- NCT02758899
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Washington University School of Medicine
Focal Segmental Glomerulosclerosis
LDL-Apheresis for FSGS CardioRenal Outcomes
Focal segmental glomerulosclerosis (FSGS) is the most common cause of end-stage renal disease (ESRD) in adolescents. The refractory nature of FSGS and a more than 30% recurrence rate after kidney transplantation renders treatment…
- Trial name
- NCT04088799
- Testing
- No intervention
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Diabetes Mellitus, Type 1
Effect of HCL Insulin Delivery System on Glycemic Control in Patients With T1D
The goal of this study is compare the effect of hybrid closed loop system (HCL) for automatic insulin dosing treatment on the glycemic control of type 1 diabetes (T1D) in patient with different initial glycated hemoglobin.
- Trial name
- NCT05924932
- Testing
- Tandem t:slim X2 with hybrid closed loop system Control IQ, glucose sensor: Dexcom G6, MiniMed 780G, with hybrid closed loop system SmartGuard, sensor Guardien 4
- Where
- Czechia
- Volunteers
- 120 people
- Sponsor
- Masaryk Hospital Usti nad Labem
Normal Eyes
Evaluation of Heidelberg Engineering SPECTRALIS OCT Signal to Noise Ratio Effect on Parameter Measurements
Evaluation of effect of various OCT scan speeds and filters on parameter measurements.
- Trial name
- NCT04961398
- Testing
- OCT imaging
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Nursing, Hysterectomy
The Effect of Game-Based Virtual Reality Application on the Development of Postoperative Care Skills of Nursing Students for Hysterectomy
This study aimed to determine the effect of game-based virtual reality application on nursing students' self-confidence in postoperative care knowledge, skills, satisfaction and learning following hysterectomy surgery.
- Conditions
- Nursing, Hysterectomy, Game-Based Learning
- Trial name
- NCT06585098
- Testing
- game based learning
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Ege University
Implant Stability
The Effect of Osseodensification on Implant Stability in Posterior Maxilla
Implants will be placed in posterior maxilla using two drilling methods; the osseodensification technique and conventional drilling protocols.
- Trial name
- NCT04442763
- Testing
- Densah Burs, Standard drills
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Healthy, Obesity
Effect of Ghrelin on Sympathetic Nervous System
Ghrelin is a newly discovered peptide that is secreted by the stomach. Its main role is to stimulate food intake but recent studies indicate that it also acts on the cardiovascular system to confer beneficial effects.
- Trial name
- NCT00912587
- Testing
- ghrelin
- Where
- Australia
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Baker Heart and Diabetes Institute
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