Clinical trials: Therapy Effect
Hip Fracture
Effect of Anesthesia Technique on Outcome After Hip Fracture Surgery in Elderly Adult Patients
Despite many previous studies, whether anesthetic technique will significantly affect overall patient outcome, morbidity and mortality in elderly hip fracture patients is controversial.
- Trial name
- NCT02458547
- Testing
- Desflurane, Propofol, Bupivacaine
- Where
- South Korea
- Volunteers
- 186 people
- Sponsor
- Yonsei University
TNF-alfa, Endotoxin Levels
Vitamin A and Response to Endotoxin
Vitamin A given as treatment and pre-treatment has reduced the severity of symptoms after infusion with endotoxin in several animal models.
- Trial name
- NCT00168649
- Testing
- Vitamin A
- Where
- Denmark
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bandim Health Project
Flipped Classroom, Episiotomy
Flipped Classroom in Episiotomy Education
This study aims to evaluate the effect of using inverted classroom design on students' knowledge, skills and anxiety levels in teaching episiotomy application and repair, one of the interventions frequently used in labour.
- Trial name
- NCT05776849
- Testing
- flipped classroom
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Sakarya University
Diabetes Mellitus, Type 2
Effects of Exercise Therapy on Ventricular and Endothelial Function in Patients After Coronary Artery Bypass Surgery
The purpose of this study was (1) to compare the peak exercise capacity and left ventricular diastolic function between patients with and without diabetes and (2) to investigate the interrelation among peak oxygen consumption…
- Trial name
- NCT01990638
- Testing
- exercise capacity test
- Where
- Taiwan
- Volunteers
- 51 people
- Sponsor
- National Taiwan University Hospital
Migraine
A Study to Learn About the Safety and Effects of Rimegepant to Prevent Migraine in Chinese Subjects.
The purpose of this study is to learn about the effects of Rimegepant to help prevent migraine. This study is seeking for participants who: Are male and female of 18 years of age or older.
- Trial name
- NCT05810038
- Testing
- Rimegepant
- Where
- 49 sites in China
- Volunteers
- 787 people
- Sponsor
- Pfizer
Non-specific Low Back Pain
The Effect of Core Stabilization Exercises in People With Chronic Low Back Pain
Low back pain is a health problem that causes clinical, social and economic losses all over the world and affects the majority of the population.
- Trial name
- NCT05302349
- Testing
- Core Exercise Group, Routine Therapy Group
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Mehmet Akif Guler
Clinical Infection, Microbial Colonization
Effect of Gut Microbiota and Fecal Inflammatory Marker on Childhood Gastroenteritis
Childhood gastroenteritis establishes gastrointestinal disease and increase the economic burden, and the pediatric population is especially vulnerable to these gastrointestinal infections.
- Conditions
- Clinical Infection, Microbial Colonization, Gastroenteritis, Inflammatory Response
- Trial name
- NCT03856138
- Where
- Taiwan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Obesity
Ankle Kinesio Taping on Balance and Functional Performance in Obese Females.
Obesity is one of the most dangerous factors affecting the joints, which must be prevented due to arthritis and the long-lasting, tiring effects that affect a person's life [1], The most important of these are foot problems due…
- Trial name
- NCT06195748
- Testing
- Kinesiotaping
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pediatric Preoperative Anxiety
Educational Cartoon to Reduce Preoperative Anxiety in Children (CALM-KIDS)
This prospective randomized controlled study aims to compare the effects of three preoperative information strategies on anxiety in children aged 7 to 12 years undergoing elective procedures under general anesthesia.
- Trial name
- CALM-KIDS (NCT07495878)
- Testing
- Educational Cartoon, Distractor Cartoon, Standard Verbal Information
- Where
- Turkey (Türkiye)
- Volunteers
- 159 people
- Sponsor
- Mehmet Burak Eşkin
Intubation; Difficult or Failed
Head Elevated Position and Hyper-angulated Video-laryngoscope Guided Intubation
Cervical immobilization with manual in-line stabilization (MILS) is recommended to prevent further neurologic injury during intubation in patients with known or suspected cervical spine injuries.
- Trial name
- NCT05671978
- Testing
- back-up head elevated position, neutral position
- Where
- South Korea
- Volunteers
- 182 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
HCC, Chemotherapy Effect
Clinical Study of Radiotherapy Combined With Donafenib for Neoadjuvant Treatment of Patients With HCC With Portal Vein Carcinoma Thrombosis
For HCC patients with combined PVTT, systemic therapy can be used as a basic approach throughout the treatment and in combination with hepatectomy, TACE, HAIC, radiotherapy, etc.
- Trial name
- NCT05022628
- Testing
- Donafenib
- Volunteers
- 30 people
- Sponsor
- Anhui Provincial Hospital
Chronic Kidney Disease, Chronic Renal Disease
Study of How the Dose of Dialysis is Affected by Dialysate Flow Rate
The purpose of this study is to look at how the dose of dialysis is affected by the rate at which dialysate flows through the dialyzer.
- Trial name
- NCT00962000
- Testing
- Dialysis Flow Rate Start 600mL/min, Dialysis Flow Rate Start 800mL/min
- Where
- 3 sites in United States
- Volunteers
- 42 people
- Sponsor
- Vantive Health LLC
Neck Pain
Effect of Neck Strength Training on Health-related Quality of Life in Females With Neck Pain
The purpose of this study is to determine whether intensive one-year neck strength training can enhance health related quality of life in females with chronic neck pain.
- Trial name
- NCT01057836
- Testing
- Neck endurance training, Stretching
- Where
- Finland
- Volunteers
- 180 people
- Sponsor
- Jyväskylä Central Hospital
Osteoarthritis, Osteoarthritis, Knee
Effects of Glucosamine and Chondroitin Sulfate Supplementation in Addition to Resistance Exercise Training and Manual Therapy in Patients With Knee Osteoarthritis
Osteoarthritis (OA) IS one of the most common joint disorders, affecting not only the joints but also the surrounding muscles, which become weak.
- Trial name
- NCT04654871
- Testing
- Chondroitin Sulfate, Resistance exercise training, Manual therapy / Joint Mobilization
- Where
- Pakistan
- Volunteers
- 24 people
- Sponsor
- Foundation University Islamabad
Heart Failure
Bioimpedance-Guided Diuretics and Cardiac Progression in Asymptomatic Heart Failure
It has not been clearly elucidated whether volume control with diuretics is essential at an early stage in patients with heart failure (HF).
- Trial name
- NCT07801144
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Kayseri Training and Research Hospital
Bipolar Disorder, Suicide
MAPS Group Therapy Model for Bipolar Disorder
This study aims to develop the MAPS(M,Monitoring;A,Assessing;P,Preventing or Reducing Relapse;S,Smart goal setting) group therapy model for bipolar disorder patients as other adjuvant clinical treatment and develop the…
- Trial name
- NCT01152034
- Testing
- psychoeducation group therapy
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Mackay Memorial Hospital
Respiratory Tract Infections, Infections
Non-specific Effects of a Modified Measles Vaccination Schedule to Prevent Allergy and Unrelated Infection in Children
The goal of this clinical trial is to evaluate the off-target/non-specific effects of the measles-mumps-rubella (MMR) vaccine in children.
- Conditions
- Respiratory Tract Infections, Infections, Allergy, Eczema
- Trial name
- NEMAU (NCT05758532)
- Testing
- Measles-Mumps-Rubella vaccine (MMR)
- Where
- Switzerland
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Laure Pittet, MD-PhD
Healthy
A Study To Estimate The Effect of PF-06650833 On The Pharmacokinetics (PK) of Oral Contraceptive (OC)
This is a Phase 1, open label, fixed sequence study of the effect of multiple dose PF-06650833 on single dose OC PK in healthy female subjects.
- Trial name
- NCT05064332
- Testing
- PF-06650833, Ethinyl estradiol (EE) and levonogestrel (LN)
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Pfizer
Breast Cancer
Study of the Effect of Eplerenone on Heart Function in Women Receiving Anthracycline Chemotherapy for Breast Cancer
Doxorubicin and other anthracyclines are commonly used to treat breast cancer and other types of cancer. Unfortunately, they can cause heart muscle damage, resulting in scarring, abnormal contraction and relaxation, and heart…
- Trial name
- NCT01708798
- Testing
- Eplerenone
- Where
- Canada
- Volunteers
- 44 people
- Sponsor
- University of British Columbia
Breast Cancer
The Effects of Pre-operative Physical Therapy Education
It is expected that patients who receive physical therapy before surgery will have greater range of motion (ROM), strength, function, satisfaction, and less swelling, pain, and anxiety following surgery compared to those in the…
- Trial name
- NCT01669187
- Testing
- Education brochure, Live education and exercise instruction
- Where
- 2 sites in United States
- Sponsor
- Oakland University
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