Clinical trials: Third Molar
Pain, Edema
Evaluation of Two Pharmacological Protocols for Pre-emptive Analgesia in Impacted Third Molar Surgery
The main aim of the study is to investigate the pre-emptive effect of dexamethasone and diclofenac associated to codeine to prevent the pain, edema and limited mouth opening at the extraction of third molar.
- Conditions
- Pain, Edema, Trismus
- Trial name
- NCT02665533
- Testing
- Dexamethasone, Diclofenac Sodium associated with Codeine
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Bone Loss, Regenerative Inflammation
Osteogenic Action of a Medical Device Based on Beta-tricalcium Phosphate (BTCP)
The general objective of this split-mouth study is to analyze the osteogenic action of BTCP during the bone regeneration process following the extraction of impacted mandibular third molars.
- Conditions
- Bone Loss, Regenerative Inflammation, Third Molars Extraction
- Trial name
- BTCP (NCT06935747)
- Testing
- Medical device: beta-tricalcium phosphate, Bovine Hydroxyapatite
- Where
- 2 sites in Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mario Pérez Sayáns
Dental Anxiety
Aromatherapy With Lavender Essential Oil as a Complementary Treatment for the Control of Dental Anxiety
Dental anxiety is a common problem in dental care, the aim of this protocol is to evaluate the effect of lavender for the control of anxiety during a surgical dental extraction.
- Trial name
- NCT04285385
- Testing
- Lavender aromatherapy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Autónoma Benito Juárez de Oaxaca
Dental Anxiety, Dental Fear
The Effect of Conscious Sedation on Acute Stress
The specific aims of the present study were to evaluate sAA responses to impacted third molar extractions at different time points in the patients under conscious sedation with local anesthesia and to examine the relationship…
- Conditions
- Dental Anxiety, Dental Fear, Tooth Extraction Status Nos
- Trial name
- NCT04207515
- Testing
- Procedures of wisdom tooth removal surgery under conscious sedation, Procedures of wisdom tooth removal surgery under local anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Impacted Third Molar Tooth
Topical Hydrocortisone for Pain and Edema Control After Third Molar Surgery
The investigators set out to develop a clinical trial in order to test the topical use of hydrocortisone as a intraoperative irrigant solution.
- Trial name
- NCT03179813
- Testing
- Hydrocortisone, Control
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Impacted Third Molar Tooth
Investigation of the Effects of H-PRF on the Period After Impacted Third Molar Tooth Extraction
After wisdom teeth are extracted, the patient may have some complaints in the post-operative period. Pain, swelling and edema are some of them.
- Trial name
- NCT06244797
- Testing
- L-PRF and H-PRF, Impacted Tooth Removal
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- esengul sen
Tooth Extraction, Dental Anesthesia
Is the Direct Inferior Alveolar Nerve Block Required for Third Lower Molar Extraction?
This study is a Randomized Controlled Trial (RCT) which objective is to compare the effectiveness, efficacy and complication associated to an infiltrative anesthetic technique for the removal of lower third molars comparing it to…
- Trial name
- NCT03443726
- Testing
- Nerve block technique, Infiltrative technique, 4% articaine 1:100.000 epinephrine
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Barcelona
The Application of Hyaluronic Acid on Teeth Bone Healing. Hyaluronic Acid Which is Widely Used in Medicine for Joint, Eye Care, Wound Healing
Effect of Injectable Hyaluronic Acid (HYADENT BG (HA)) on Bone Healing in Extraction Sockets
Complications such as postoperative pain and delayed socket healing are relatively common following surgical extraction of mandibular third molars.
- Trial name
- NCT07318298
- Testing
- Surgical extraction of wisdom teeth, bone biobsy
- Where
- Jordan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Jordan University of Science and Technology
Postoperative Complications, Third Molar
Complications After Lower Third Molar Surgery
Objectives: The objective of the study was to evaluate the effectiveness of a prophylactic single preoperative dose of amoxicillin in decreasing complications after lower third molar surgery.
- Trial name
- NCT03130933
- Testing
- Lower third molar surgery, Amoxicillin 500 Mg
- Where
- Croatia
- Volunteers
- 400 people
- Sponsor
- University of Zagreb
Dental Anxiety, Third Molar Extraction
Clinical Study Evaluating the Effect of Virtual Reality on Reducing Patients' Anxiety During Wisdom Teeth Extraction
Dental anxiety is common during third molar extractions and may exacerbate pain perception. Local anesthesia does not prevent exposure to stress-inducing stimuli.
- Conditions
- Dental Anxiety, Third Molar Extraction, Oral Surgery
- Trial name
- SEREIN (NCT07273968)
- Testing
- Virtual reality HypnoVR® (VR headset + hypnotic software), Control Group (No VR)
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Impacted Wisdom Tooth, Pain
Investigation of Effectiveness of Local Antibiotic With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo
The aim of this study was investigate the effectiveness of Local Antibiotic Applications With Platelet Rich Fibrin on Third Molar Surgery Outcomes In Vivo and In Vitro.
- Conditions
- Impacted Wisdom Tooth, Pain, Staphylococcus Aureus
- Trial name
- NCT05678296
- Testing
- Diagnosis, Analgesic, traditional osteotomies
- Where
- Cyprus
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ceren Melahat Donmezer
Pain, Postoperative
Postoperative Course Following Wisdom Tooth Surgery
The purpose of this study is to determine how quality of life changes after surgical removal of wisdom teeth
- Trial name
- NCT00921479
- Where
- 2 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Ullevaal University Hospital
Molar, Third, Pain
Influence of CYP2C9 Genotype on Clinical Efficacy of Tenoxicam
The goal of this study is to evaluate the different gene haplotypes for the clinical efficacy of tenoxicam after third lower molar surgery for pain, edema and trismus, adverse reactions, need of rescue medication, patient…
- Trial name
- NCT04182191
- Testing
- Tenoxicam
- Where
- Brazil
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Dental Pain
Study of Acetaminophen (ACE) in Post-operative Dental Pain
This is a dental pain study evaluating the efficacy and safety of a single dose of test acetaminophen (ACE) (1000 mg) compared to commercial acetaminophen (1000 mg), ibuprofen (IBU) (400 mg), and placebo over a 6 hour period.
- Trial name
- NCT02320708
- Testing
- Acetaminophen (ACE) (1000 mg), Commercial ACE (1000 mg), Commercial Ibuprofen (IBU) (400 mg)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Johnson & Johnson Healthcare Products Division of McNEIL-PPC, Inc.
Anesthesia
A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation
Hypothesis: A combination of midazolam with dexmedetomidine for sedation during third molar surgery will provide 1) superior patient satisfaction, 2) superior operator satisfaction and 3) no significant hemodynamic or respiratory…
- Trial name
- NCT03255824
- Testing
- Dexmedetomidine and Midazolam, Propofol, Midazolam, and Fentanyl
- Where
- United States
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Impacted Third Molar Tooth
Comparison of the Use of Dexamethasone and Diclofenac Sodium in Immediate Post-Operative Care in Third Molar Surgery
The investigators will select 30 patients with symmetrical impaction of third molars, according to Pell and Gregory dental impaction classification, who would be submitted to two surgical procedures, right and left, and in both…
- Trial name
- NCT02698306
- Testing
- Dexamethasone, Diclofenac Sodium
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hospital Geral de Vila Penteado
Impacted Wisdom Teeth
Evaluation of the Effect of Watching Surgery Videos on Social Media on Anxiety Before Impacted Wisdom Tooth Extraction
Surgical extraction of impacted wisdom teeth creates a high level of anxiety on patients. Anxiety in patients can affect the difficulty of tooth extraction, prolong the duration of surgery and increase post-operative pain.
- Trial name
- NCT05890040
- Testing
- questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Tooth Diseases, Piezoelectric Technique
A New Piezoelectric Technique in Third Molar Surgery
The present study aims to analyze the effect of the piezoelectric technique in third molar surgery in terms of facial swelling, trismus and pain in a split-mouth randomized controlled clinical trial
- Conditions
- Tooth Diseases, Piezoelectric Technique, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT06212232
- Testing
- Piezoelectric surgery
- Where
- Italy
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Pain, Postoperative, Edema
Effectiveness of Light-emitting Diode (LED) Photobiomodulation in the Extraction of Retained Lower Third Molars
In dentistry, one of the most common surgical procedures is the removal of included third molars. This surgery generates great morbidity to patients for causing pain, edema and trismus due to surgical trauma.
- Conditions
- Pain, Postoperative, Edema, Trismus, Quality of Life
- Trial name
- NCT03442166
- Testing
- LED group
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Impacted Third Molar Tooth, Pain, Acute
Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction
This research study will evaluate inter-individual variability in the analgesic response to the non-steroidal anti-inflammatory drug (NSAID) ibuprofen after third molar extraction surgery.
- Trial name
- NCT03893175
- Testing
- Ibuprofen, Acetaminophen, Oxycodone
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Pennsylvania