Clinical trials: Third Molar
Pain, Trismus
2%-Mepivacaine With Two Different Vasoconstrictors Solutions in Third Molar Surgery a Comparative Study
Dental treatments, particularly third molars extraction, can become extremely uncomfortable and painful. They are associated to anxiety, fear and many other unpleasant sensations.
- Conditions
- Pain, Trismus, Edema
- Trial name
- NCT02603198
- Testing
- mepivacaine chloridrato epinephrine, mepivacaine chloridrato levonordefrin
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Photodynamic Therapy, Third Molar Extraction
The Effect of Photodynamic Therapy on Post-extraction Third Molar
The extraction of lower third molars is one of the most frequent procedures in oral surgery. For this reason, the extraction of these teeth generally requires a surgical approach involving the elevation of a mucoperiosteal flap…
- Conditions
- Photodynamic Therapy, Third Molar Extraction, Antimicrobial Photodynamic Therapy
- Trial name
- NCT06964178
- Testing
- Experimental: antimicrobial photodynamic therapy (aPDT) after extraction of third molar
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universita di Verona
Tooth, Impacted
Piezoelectric Vibrations and Tissue, Cellular and Molecular Mechanisms of Oral Wound Healing After Third Molar Surgery
The aim of this clinical trial is to investigate and compare the effect of piezoelectric surgery on tissue, cellular and molecular level of oral surgical wound healing and postoperative outcomes (pain, swelling, trismus) after…
- Trial name
- NCT02942108
- Testing
- piezo surgery, conventional surgery
- Where
- Serbia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Dentin Caries
A Study to Evaluate Physiologic Dentin Regeneration and Safety of KH001 in the Administration of Erupted Wisdom Tooth With Dentin Caries
The purpose of this study is to evaluate physiologic dentin regeneration and safety of KH001 in the administration of erupted wisdom tooth with dentin caries
- Trial name
- NCT06580678
- Testing
- KH001
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- Byoung-Moo Seo
Impacted Third Molar Tooth, Dental Anxiety
Should Preoperative Information Before Impacted Third Molar Extraction?
The main objective of the present study was to evaluate the effects of different preoperative information techniques (verbal, written, video with background audio, and silent video with subtitles) on patients' anxiety levels…
- Trial name
- NCT05548790
- Testing
- Spielberger State Anxiety Inventory (STAI-S), Dental Fear Scale (DFS), Modified Dental Anxiety Scale (MDAS)
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Impacted Mandibular Third Molar Extraction
Effect of Titanium-Prepared Platelet-Rich Fibrin and Low-Level Laser Therapy on Postoperative Morbidity After Mandibular Third Molar Surgery
This randomized double-blind clinical trial aims to evaluate the effects of titanium-prepared platelet-rich fibrin (T-PRF), low-level laser therapy (LLLT), and their combination on postoperative outcomes following surgical…
- Trial name
- NCT07748585
- Testing
- Titanium-Prepared Platelet-Rich Fibrin (T-PRF), Low-Level Laser Therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cyprus Health and Social Sciences University
Surgical Flaps, Oral Surgical Procedures
Oral Flap Outline and Local Blood Supply After Surgical Removal of Lower Third Molar Teeth
Wisdom teeth in the lower jaw are frequently buried in bone and must be taken out surgically. To reach the tooth, the surgeon lifts the gum away from the bone as a flap, and the shape of that flap is left to the surgeon's…
- Conditions
- Surgical Flaps, Oral Surgical Procedures, Regional Blood Flow, Tooth, Impacted
- Trial name
- NCT07758192
- Testing
- Sulcular flap elevation for wisdom tooth removal, Three-cornered flap elevation for wisdom tooth removal
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Betül Taş Özyurtseven
Tooth Displacement
Retrieval of Displaced Mandibular Third Molar Teeth
The aim of this study is to compare multi-detector CT and CBCT as pre-surgical diagnostic imaging before surgical retrieval of iatrogenic displaced mandibular third molar teeth/roots.
- Trial name
- NCT06060522
- Testing
- CT, CBCT
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Tanta University
Wound Healing Complication, Oral Surgery
Comparison of Three Types of Sutures in Oral Surgery. Study of Bacterial Colonization, Tissue Reaction and Clinical Characteristics: Randomized Clinical Study
Considering the wide variety of surgical sutures currently marketed in the field of Dentistry, it was decided to conduct a study comparing the microbial adhesion and antibacterial activity of three different types of sutures used…
- Conditions
- Wound Healing Complication, Oral Surgery, Third Molar Extraction, Oral Infection
- Trial name
- NCT06864559
- Testing
- To Compare 3 different suture materials used in oral surgery
- Volunteers
- 24 people
- Sponsor
- Universidad de Granada
Pain, Other Surgical Procedures
Comparison of the Clinical Efficacy of Naproxen, Associated or Not With Esomeprazol, in Lower Third Molar Removal
The present clinical trial randomized compared the clinical efficacy of the naproxen associated or not with esomeprazol, for the removal of lower third molars.
- Conditions
- Pain, Other Surgical Procedures, Impacted Third Molar Tooth
- Trial name
- NCT02494856
- Testing
- Surgery with Naproxen, Surgery with Naproxen and Esomeprazole
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Giovana Maria Weckwerth
Facial Swelling, Tooth Position Anomalies
The Use of Platelet-rich-fibrin in Lower Third Molar Surgery.
The present study aims to analyze the effect of PRF (Platelet-rich-fibrin) in terms of facial swelling, trismus and pain after surgical removal of mandibular third molar (M3M) in a split-mouth randomized controlled clinical trial.
- Conditions
- Facial Swelling, Tooth Position Anomalies, Tooth, Impacted, Tooth Extraction Status Nos
- Trial name
- NCT06165692
- Testing
- PRF
- Where
- Italy
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Amerigo Giudice
Tooth, Impacted
Comparison Between the Lingually Based and the Buccally Based Triangular Flap Design in the Surgical Removal of Impacted Mandibular Third Molars
The primary objective of this study was to compare between the lingually based triangular flap with the buccally based triangular flap in the surgical removal of impacted mandibular third molars.
- Trial name
- NCT04192864
- Testing
- Lingually based triangular flap, Buccally based triangular flap
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Nourhan M.Aly
Alveolar Osteitis, Impacted Lower Third Molar
Chlorhexidine Versus Normal Saline Socket Irrigation for Prevention of Dry Socket After Lower Wisdom Tooth Extraction
Dry socket, also called alveolar osteitis, is a painful complication that can occur after tooth extraction, particularly following removal of impacted lower wisdom teeth.
- Trial name
- NCT07814430
- Testing
- Chlorhexidine Socket Irrigation, Normal Saline Socket Irrigation
- Where
- Pakistan
- Volunteers
- 174 people
- Sponsor
- CMH Lahore Medical College and Institute of Dentistry
Acute Postoperative Pain, Dental Pain
A Study of CYT-1010 in Healthy Volunteers and Participants With Acute Pain After Third Molar Extraction
The primary objective of this trial is to assess the safety and tolerability of single, ascending doses of CYT-1010 in healthy male and female volunteers and in the treatment of acute postoperative pain after third molar…
- Trial name
- NCT07905105
- Testing
- CYT-1010
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Cytogel Pharma, LLC
Periodontal Pocket, Swelling Lips & Face
The Efficacy of Autogenous Dentin Graft in Mandibular Wisdom Tooth Extraction
The study aimed to investigate clinical effect of autogenous dentin graft on patients following mandibular wisdom tooth extraction.
- Conditions
- Periodontal Pocket, Swelling Lips & Face, Trismus, Pain, Acute
- Trial name
- NCT06073639
- Testing
- Autogenous dentin graft
- Where
- Vietnam
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Pain, Oral Surgery
Pulsed Electromagnetic Fields for Postoperative Pain: a Linical Trial in Humans
This randomized clinical trial was designed to assess the clinical efficacy of Pulsed electromagnetic field PEMF delivered with a wearable device in terms of postoperative pain and quality of healing after mandibular third molar…
- Conditions
- Pain, Oral Surgery, Third Molar Extraction
- Trial name
- NCT02273999
- Testing
- RecoveryRx™
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Acute Pain, Postoperative Pain
Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain
The goal of the present phase IIb clinical trial was to compare the safety and efficacy of the fixed-dose combination etoricoxib-tramadol 120mg/100mg tablet (once a day, for three days) versus naproxen 220mg tablet plus tramadol…
- Trial name
- NCT05995912
- Testing
- etoricoxib-tramadol, Naproxen, Tramadol
- Where
- Mexico
- Volunteers
- 58 people
- Sponsor
- Laboratorios Liomont
Dental Anxiety, Third Molar Extraction Surgery
Effect of Aromatherapy and Music Therapy on Physiological Response and Pain During Mandibular Third Molar Extraction
The goal of this clinical trial is to compare the effects of aromatherapy and music therapy on physiological responses and intraoperative pain in patients with moderate to severe dental anxiety undergoing mandibular third molar…
- Trial name
- AROMUSIC-M3 (NCT07647419)
- Testing
- Aromatherapy, Music Therapy
- Where
- Peru
- Volunteers
- 102 people
- Sponsor
- Universidad Científica del Sur
Tooth Impacted
Acute Inflammation After Wisdom Tooth Removal
Third molar (wisdom teeth) extraction is one of the most frequent intervention in dentistry. Nevertheless, little is known about the level of general body inflammation of subjects with impacted or semi-impacted third molars.
- Trial name
- OTTO-SYST (NCT03048175)
- Testing
- Wisdom tooth removal
- Volunteers
- 40 people
- Sponsor
- University of Pisa
Alveolitis of Jaw, Alveoli, Teeth; Inflammation
Examination of the Prevention and Treatment Modalities of Alveolitis in Relation With Impacted Teeth Surgery
In the everyday clinical practice the incidence of minor complications is approximately 15-20% of the total number of third molar removals. Alveolitis (dry socket syndrome) may arise in 30-40% of the surgical tooth removals.
- Conditions
- Alveolitis of Jaw, Alveoli, Teeth; Inflammation, Dry Socket, Impacted Third Molar Tooth
- Trial name
- AITS (NCT03741894)
- Testing
- Iodoform, Wound closure using sutures, Chlorhexidine
- Where
- Hungary
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Pecs