Clinical trials: Third Molar Surgery
Morbidity, Third Molars Extraction
Betamethasone and Complications of Lower Third Molar Surgery
Pain, swelling, and trismus are common sequalae of surgical removal of impacted third molars. The aim of this study is to evaluate effect of local administration of betamethasone, into the pterygomandibular space, on these…
- Conditions
- Morbidity, Third Molars Extraction, Steroid Injection
- Trial name
- NCT07297264
- Testing
- Betamethasone, normal saline
- Where
- Iraq
- Volunteers
- 40 people
- Sponsor
- Shehab Ahmed Hamad
Anxiety
Efficacy of Clonidine and Propranolol in Dentistry (AAA)
The aim of the study is to determine the efficacy of clonidine and propranolol for transient anxiety management and intra and postoperative pain in patients undergoing ambulatory surgery of third molar.
- Trial name
- NCT01784250
- Testing
- Clonidine, Propranolol
- Where
- Colombia
- Volunteers
- 60 people
- Sponsor
- CES University
Pain, Post-operative, Third Molar
Controlled Trial to Determine Most Effective Post-Operative Analgesia After Third Molar Extraction
This is a prospective randomized clinical trial that will investigate which post-operative medications in conjunction with a multimodal analgesia approach can most effectively control post-operative pain and reduce opioid…
- Conditions
- Pain, Post-operative, Third Molar, Oral Surgery, Pain, Acute
- Trial name
- NCT06484439
- Testing
- Ketorolac, Oxycodone, Acetaminophen
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, San Diego
Post-Operative Wound Infection
A Tetracycline Drain Reduces Alveolar Osteitis in Third Molar Surgery
The aim of this study was to investigate the effect of an oxytetracycline impregnated gauze drain on the incidence of alveolar osteitis (AO) and postoperative pain during the first week after mandibular third molar surgery.
- Trial name
- Wisdomsteeth (NCT03494972)
- Testing
- Tetracyclin ointment
- Where
- Norway
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Oslo
Impacted Third Molar Tooth
Chlorhexidine Gel Versus Alvogyl Following Surgical Extraction of Impacted Mandibular Third Molar
Background: One of the most frequent surgical operations in dentistry is the surgical extraction of the impacted mandibular third molar, which is accompanied by a sequelae of swelling, trismus, and pain.
- Trial name
- NCT06144983
- Testing
- Alvogyl, Chlorhexidine Gluconate
- Where
- Iraq
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Dental Anxiety, Dental Fear
The Effect of Conscious Sedation on Acute Stress
The specific aims of the present study were to evaluate sAA responses to impacted third molar extractions at different time points in the patients under conscious sedation with local anesthesia and to examine the relationship…
- Conditions
- Dental Anxiety, Dental Fear, Tooth Extraction Status Nos
- Trial name
- NCT04207515
- Testing
- Procedures of wisdom tooth removal surgery under conscious sedation, Procedures of wisdom tooth removal surgery under local anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Beykent
Dental Pain
Study of Diclofenac Capsules to Treat Dental Pain
The purpose of this study is to determine whether Diclofenac Test Formulation Capsules are safe and effective for the treatment of dental pain.
- Trial name
- NCT00985439
- Testing
- Diclofenac Test (lower dose), Diclofenac Test (upper dose), Celecoxib 400 mg
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Iroko Pharmaceuticals, LLC
Surgical Site Infection
Prophylactic Effects for Preventing Surgical Site Infection in Third Molar Surgery
The purpose of this study is to determine the incidence of surgical site infection (SSIs) after third molar surgery for different duration of intravenous ampicillin administration.
- Trial name
- NCT06368102
- Testing
- Ampicillin
- Where
- Japan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Uji Takeda Hospital
Pain, Oral Surgery
Pulsed Electromagnetic Fields for Postoperative Pain: a Linical Trial in Humans
This randomized clinical trial was designed to assess the clinical efficacy of Pulsed electromagnetic field PEMF delivered with a wearable device in terms of postoperative pain and quality of healing after mandibular third molar…
- Conditions
- Pain, Oral Surgery, Third Molar Extraction
- Trial name
- NCT02273999
- Testing
- RecoveryRx™
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Padova, School of Dental Medicine
Impacted Mandibular Third Molar
The Effect of Topical Application of Hyaluronic Acid and Melatonin Mixture Following Surgical Extraction of Impacted Mandibular Third Molars .
This randomized controlled clinical trial aims to evaluate the clinical and radiographical effects of the application of a mixture of hyaluronic acid and melatonin after surgical extraction of impacted mandibular third molars.
- Trial name
- NCT07735806
- Testing
- Hyaluronic acid and Melatonin mixture, Gel foam
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Kafrelsheikh University
Impacted Mandibular Third Molar Extraction
Effect of Kinesio Tape Versus Systemic Dexamethasone on Postsurgical Sequels Following Extraction of Impacted Mandibular Third Molars
The surgical removal of lower wisdom teeth is a common procedure that can cause pain, facial swelling, and difficulty in opening the mouth after surgery.
- Trial name
- NCT07353593
- Testing
- Kinesio Tape application, Intramuscular Injection of Dexamethasone, control
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ashraf elanzy
Trismus, Swelling
Comparison of Two Different Suture Knot Techniques on Post-Operative Trismus and Swelling After Impacted Third Molar Surgery
To compare the two different suture knot techniques, locked and unlocked, in terms of mean on postoperative trismus and swelling after impacted mandibular third molar surgery.
- Trial name
- Impacted molar (NCT07327762)
- Testing
- locking and non locking suture techniques, non locking suture technique
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Watim Medical & Dental College
Cold Therapy
Is Cryotherapy Beneficial After Surgical Removal of Impacted Lower Third Molars?
The present study aimed to investigate the effects of cryotherapy on postoperative parameters (pain intensity, edema, trismus, and the quality of life) after lower third molar extraction.
- Trial name
- NCT07370870
- Testing
- Cold Therapy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henrique Tedesco
Impacted Third Molar Tooth
Dexamethasone in Lower Third Molar Surgery
The aim of this randomized double-blind cross over clinical trial is to investigate effectiveness of different routes of applications (intramuscular and submucous at the site of surgery) and doses (4 mg and 8 mg) of Dexamethasone…
- Trial name
- NCT02416869
- Testing
- Intramuscular application, Submucosal application, 4mg Dexamethasone submucosal
- Where
- Serbia
- Volunteers
- 60 people
- Sponsor
- University of Belgrade
Impacted Third Molar Tooth
EFFICACY OF ICE PACK THERAPY AFTER IMPACTED THIRD MOLAR SURGERY
this study evaluates the effect of cold application after impacted third molar extractions. Patients have bilateral impacted third molar tooth included in this study.
- Trial name
- NCT03261869
- Testing
- Cold application
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Baskent University
Pain
Study to Compare the the Analgesic Efficacy and Tolerability of Meloxicam Versus Placebo and Ibuprofen in the Treatment of Pain After Surgery of the Third Molar
To assess the analgesic efficacy and tolerability of meloxicam 15 mg, 7.5 mg, 3.75 mg and 1.875 mg oral (rapid release tablet) compared with placebo and ibuprofen 400 mg and 200 mg administered in a single dose, over an…
- Trial name
- NCT02183051
- Testing
- Meloxicam 7.5 mg, Meloxicam 3.75 mg, Meloxicam 1.875 mg
- Volunteers
- 381 people
- Sponsor
- Boehringer Ingelheim
Fibrin/Therapeutic Use, Blood Platelets
Effects of the Use of Platelet-rich Fibrin on Bone Regeneration After Impacted Third Molar Surgery
The purpose of this study is to evaluate the bone regeneration after impacted third molar surgery on split mouth design using platelet-rich fibrin.
- Conditions
- Fibrin/Therapeutic Use, Blood Platelets, Molar, Third, Bone Regeneration
- Trial name
- NCT02890680
- Testing
- Platelet-rich fibrin, Control group
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Molar, Third
Pain and Trismus Control in Third Molar Surgery: Ibuprofen, Ketamine, and Their Combination
The goal of the clinical trial is to compare the efficacy of ibuprofen, ketamine, and their combination in managing postoperative pain and trismus following third molar surgery.
- Trial name
- NCT05923775
- Testing
- Impacted third molar surgey
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Cihan Topan
Trismus, Edema
Investigation of the Effects of CGF and A-PRF on Pain, Edema and Trismus After Impacted Lower Third Molar Surgery
The objective of this case-control intervention study is to explore the effectiveness of Concentrated Growth Factor (CGF) and Advanced Platelet Rich Fibrin (A-PRF) on Pain, Edema and Trismus After Impacted Lower Third Molar…
- Conditions
- Trismus, Edema, Pain, Post-Op Complication
- Trial name
- NCT03690167
- Testing
- Concentrated Growth Factor (CGF), Advanced Platelet Rich Fibrin (A-PRF), Control
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Dr. Damla Torul
Pain, Sedation
A Study to Assess the Analgesia and Sedation Using Intranasal Dexmedetomidine in Third Molar Surgery Under Local Anaesthesia
Dental procedures such as wisdom tooth removal evoke very high levels of patients' anxiety and it is, therefore, common practice to provide concomitant pharmacologic sedation.
- Trial name
- NCT01132794
- Testing
- Intranasal dexmedetomidine
- Where
- Hong Kong
- Sponsor
- The University of Hong Kong