Clinical trials: Thoracentesis
Cancer
The Use of the ActiSight™ Needle Guidance System in Patients Undergoing CT-Guided With Lesions Smaller Than 15 mm
This will be a prospective, single-arm, single-center, open-label study to evaluate the use of the ActiSight™ Needle Guidance System in patients with lung lesions smaller than 15 mm undergoing CT-guided percutaneous chest…
- Trial name
- ActiSight (NCT01318473)
- Testing
- ActiSight™ Needle Guidance System
- Volunteers
- 25 people
- Sponsor
- ActiViews Ltd.
Hepatic Hydrothorax
Efficacy & Safety of Pigtail Catheter Drainage Versus Need Based Thoracocentesis for Recurrent Hepatic Hydrothorax.
In cirrhotic patients with recurrent hepatic hydrothorax liver transplantation is a definitive treatment. But a significant number of individual are ineligible for liver transplantation.
- Trial name
- NCT06007820
- Testing
- Large Volume Thoracocentesis, Pigtail Catheter
- Where
- India
- Volunteers
- 70 people
- Sponsor
- Institute of Liver and Biliary Sciences, India
Medical Thoracoscopy
Surgical Site Preparation in Subjects Undergoing Medical Thoracoscopy
Medical thoracoscopy is the preferred procedure for performing pleural biopsy in patients with pleural effusions that remain undiagnosed after pleural fluid analysis.
- Trial name
- CAPTAIN (NCT05430308)
- Testing
- Chlorhexidine scrub, Povidone-iodine
- Where
- 2 sites in India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Pleural Effusion, Chronic Kidney Disease
Pleural Effusion Types in Chronic Kidney Disease
The purpose of this observational study is to understand the causes of pleural effusion (a buildup of fluid around the lungs) in patients with advanced Chronic Kidney Disease (CKD Stages 3 to 5).
- Trial name
- NCT07547852
- Volunteers
- 100 people
- Sponsor
- Assiut University
Ovarian Cancer, Primary Peritoneal Cancer
Collection of Malignant Ascites, Pleural Fluid, and Blood From People With Solid Tumors
Background: Researchers want to study fluids and blood of people with cancer. The fluids are from the abdomen and around the lungs. Studying these might help researchers learn about the biology of cancer.
- Conditions
- Ovarian Cancer, Primary Peritoneal Cancer, Fallopian Tube Cancer, Cancer
- Trial name
- NCT03189108
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- National Cancer Institute (NCI)
Malignant Pleural Effusion, Lung Neoplasms
Quantitative Diaphragmatic Ultrasound Evaluation in Pleural Effusions : A Feasability Study
Malignant pleural effusions cause breathlessness and impairs quality of life. Thoracocentesis is frequently used to relieve breathlessness. The severity of breathlessness correlates poorly with the size of the effusion.
- Trial name
- ADD-Echo (NCT04264325)
- Testing
- diaphragmatic ultrasound measure
- Where
- France
- Volunteers
- 15 people
- Sponsor
- University Hospital, Strasbourg, France
Pleural Effusion, Pleural Diseases
Vacuum vs Manual Drainage During Unilateral Thoracentesis
The purpose of this study is to determine if there are any differences in terms of safety, pain, or drainage speed between thoracenteses via manual drainage vs vacuum suction.
- Conditions
- Pleural Effusion, Pleural Diseases, Thoracic Diseases
- Trial name
- NCT03496987
- Testing
- Vacuum Bottle Drainage
- Volunteers
- 100 people
- Sponsor
- Yale University
Heart Failure, Pleural Effusion
Thoracentesis to Alleviate Cardiac Pleural Effusion
The present study will examine the comparative effectiveness of two treatment strategies currently used in the treatment of patients with systolic heart failure presenting with pleural effusion.
- Trial name
- TAP-IT (NCT05017753)
- Testing
- Thoracentesis, Standard-of-care medical treatment
- Where
- 10 sites in Denmark
- Volunteers
- 135 people
- Sponsor
- Bispebjerg Hospital
Pleural Effusion
Sustained Effects of Thoracocentesis in Mechanically Ventilated Patients
Collections of fluid around the lung (pleural effusions) are common in patients on mechanical ventilation. Long stays on mechanical ventilation can lead to serious complications such as pneumonia and are associated with…
- Trial name
- NCT00915161
- Where
- United Kingdom
- Volunteers
- 10 people
- Sponsor
- Oxford University Hospitals NHS Trust
Biopsy
Safety & Accuracy of the ActiSight Needle Guidance System in Percutaneous Chest Aspiration and Biopsy
This study is intended to provide clinical data regarding safety and accuracy of the ActiSight™ Needle Guidance System in assisting Chest CT guided biopsies.
- Trial name
- ANGS-PCAB (NCT00814450)
- Testing
- Biopsy needle guidance system (ActiSight™)
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- ActiViews Ltd.
Pleural Effusion
Impact of Pleural Manometry on Chest Discomfort After Therapeutic Thoracentesis
This randomized controlled trial attempts to determine whether the measurement of pleural pressures during therapeutic thoracentesis affects the development of chest discomfort after the procedure.
- Trial name
- NCT02677883
- Testing
- Manometry-guided thoracentesis, Symptom-guided thoracentesis
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Pleural Effusion, Pleurodesis
Betadine Pleurodesis Via Tunneled Pleural Catheters
The purpose of this study is to determine whether betadine (povidone-iodine) instillation during routine indwelling Tunneled Pleural Catheter (TPC) placement is efficacious in promoting pleurodesis and thus reducing the time to…
- Conditions
- Pleural Effusion, Pleurodesis, Malignant Pleural Effusion, Pleural Effusion Due to Congestive Heart Failure
- Trial name
- NCT02975921
- Testing
- Povidone-Iodine
- Sponsor
- Yale University
Malignant Pleural Effusion, Exudative Pleural Effusion
Ultrasound-guided Biopsy of the Pleura as a Supplement to Extraction of Fluid in Patients With One-sided Fluid in the Pleura
The research group will investigate the diagnostic effect of early introduction of ultrasound guided pleural biopsy in the work-up of patients with one-sided pleural effusion, suspected of malignant pleural effusion.
- Trial name
- NCT04236037
- Testing
- ultrasound-guided pleural biopsy, Thoracentesis
- Where
- 2 sites in Denmark
- Volunteers
- 5 people
- Sponsor
- Naestved Hospital
Respiratory Instability
Bed Side Thoracentesis Among Non-Ventilated Patients With Respiratory Instability
The purpose of the trial is to evaluate the effectiveness of moderate to large volume thoracentesis (TC) in non-ventilated patients in Internal Medicine admitted due to, or suffer from respiratory instability.
- Trial name
- NCT02436850
- Testing
- Thoracentesis
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Soroka University Medical Center
Pleural Effusion, Exudative Pleuritis
Pathophysiological Effects of Intrapleural Pressure Changes During Therapeutic Thoracentesis
Research project objectives. The project includes eight research hypotheses and eight corresponding study objectives. The most relevant objectives are: Analysis of lung function and gas exchange parameters in relation to the…
- Trial name
- NCT02192138
- Testing
- Therapeutic thoracentesis, Pleural catheter, Pleural manometer
- Where
- Poland
- Volunteers
- 61 people
- Sponsor
- Medical University of Warsaw
Pleural Effusion Disorder, Re-expansion Pulmonary Edema
Predictive Role of Lung Ultrasound in Re-Expansion Pulmonary Edema During Thoracocentesis
This study evaluates the feasibility, safety, and predictive role of dynamic bedside Lung Ultrasound (LUS) during therapeutic thoracocentesis in patients with moderate-to-massive pleural effusions.
- Conditions
- Pleural Effusion Disorder, Re-expansion Pulmonary Edema, Pulmonary Edemas
- Trial name
- NCT07875764
- Testing
- Serial Bedside Lung Ultrasound (LUS) Protocol
- Where
- Egypt
- Volunteers
- 23 people
- Sponsor
- Delta University for Science and Technology
Pleural Effusion, Thoracic Effusion
The Safety of Thoracentesis, Tunneled Pleural Catheter, and Chest Tubes in Patients Taking Novel Oral Anti-Coagulants
To assess risks of bleeding in those individuals receiving Novel Oral Anti-Coagulant (NOAC) medications, admitted to the hospital and require thoracentesis, chest tube or tunneled pleural catheter placement.
- Trial name
- NCT03535883
- Testing
- Novel Oral Anti-Coagulants
- Where
- United States
- Volunteers
- 590 people
- Sponsor
- Yale University
Congestive Heart Failure(CHF), Pleural Effusion Due to Congestive Heart Failure
DRAIN: DRainage in Acute Decompensated Heart faIlure With Pleural effusioNs
The goal of this study is to assess if removal of fluid around the lungs (pleural effusion) by a routine procedure called as thoracentesis is helpful to decrease shortness of breath in hospitalized patients with congestive heart…
- Trial name
- DRAIN-IT (NCT07419360)
- Testing
- Thoracentesis
- Where
- United States
- Volunteers
- 216 people
- Sponsor
- Albany Medical College
Thoracentesis, Pleural Effusions, Chronic
GRAvity- Versus Wall Suction-drIven Large Volume Thoracentesis: a RAndomized Controlled Study (GRAWITAS Study)
The primary objective of this study is to compare gravity-driven versus wall suction-driven large volume therapeutic thoracentesis on the development of chest discomfort during the procedure.
- Conditions
- Thoracentesis, Pleural Effusions, Chronic, Pulmonary Edema
- Trial name
- NCT05131945
- Testing
- Standard Suction Thoracentesis, Gravity Thoracentesis
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- M.D. Anderson Cancer Center
Pleural Effusion, Transudative Pleural Effusion
Evaluation of Transthoracic Ultrasonography in Differentiating Pleural Effusions
Pleural effusion is a condition where excess fluid builds up in the space between the lungs and the chest wall. To properly treat this condition, doctors must determine if the fluid is a "transudate" (usually resulting from…
- Conditions
- Pleural Effusion, Transudative Pleural Effusion, Exudative Pleural Effusion
- Trial name
- NCT07513909
- Volunteers
- 90 people
- Sponsor
- Assiut University