Clinical trials: Thoracic Aortic Aneurysm
Acute Coronary Syndrome, High-Risk Chest Pain
BREVOC Study: Exhaled VOCs for High-Risk Chest Pain in the ED
Study Objectives 1. Screening and identification of diagnostic biomarkers: To establish the exhaled volatile organic compound (VOC) profile of patients with acute high-risk chest pain and to differentiate high-risk chest pain…
- Conditions
- Acute Coronary Syndrome, High-Risk Chest Pain, Volatile Organic Compounds
- Trial name
- BREVOC (NCT07379567)
- Testing
- observational study
- Volunteers
- 6,000 people
- Sponsor
- Qilu Hospital of Shandong University
Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
CAAAs, TAAAs, Aortic Arch Aneurysms or Dissections With Fenestrated/Branched Stent Graft
The purpose of this study is to gather safety and effectiveness of the Zenith t-Branch and customized physician-specified stent-graft with a combination of fenestrations and/or branches to repair aortic aneurysm.
- Conditions
- Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Aortic Arch Dissection
- Trial name
- NCT02089607
- Testing
- CAAA and TAAA Arm, Aortic Arch Aneurysm Arm
- Where
- 3 sites in United States
- Volunteers
- 760 people
- Sponsor
- Gustavo S Oderich
Acute Aortic Dissection, Thoracic Aortic Aneurysm
Genetic Architecture of Acute Aortic Syndromes and Aortic Aneurysm.
The aim of this study is to explore the genetic information associated with the development of TAA and aAD in individuals without history or syndromic features (Marfan syndrome, Ehlers-Danlos syndrome, Turner syndrome etc.) for…
- Trial name
- NCT06353607
- Where
- Switzerland
- Volunteers
- 730 people
- Sponsor
- University Hospital, Basel, Switzerland
Aortic Dissection, Aortic Root Aneurysm
Safety and Efficacy of the Minimally Invasive Bentall Procedure Via a Small Right Intercostal Incision in Patients With Aortic Root Lesions
This study intends to include patients who had aortic root lesions and were treated with Bentall surgery from January 2019 to July 2023 in the First Affiliated Hospital of Xi'an Jiaotong University.
- Conditions
- Aortic Dissection, Aortic Root Aneurysm, Minimally Invasive Surgical Procedures
- Trial name
- Mini-Bentall (NCT06177548)
- Testing
- Minimally invasive Bentall procedure
- Where
- China
- Volunteers
- 350 people
- Sponsor
- First Affiliated Hospital Xi'an Jiaotong University
Aortic Arch, Aneurysm
Arch Size Study for Anatomical Variations
The aortic arch with a common origin of the innominate and left carotid artery (CILCA) prevalence in the general population is 13.6%.
- Conditions
- Aortic Arch, Aneurysm, Dissection, Aortic
- Trial name
- NCT06235619
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- IRCCS San Raffaele
Aortic Aneurysm, Thoracic, Penetrating Ulcer
RelayPro Thoracic Stent-Graft in Subjects With Thoracic Aortic Aneurysms and Penetrating Atherosclerotic Ulcers
Investigate the safety and effectiveness of the RelayPro Thoracic Stent-Grafts in subjects with thoracic aortic aneurysms (TAA) and penetrating atherosclerotic ulcers (PAU) of the descending thoracic aorta.
- Trial name
- RelayPro-A (NCT02818972)
- Testing
- RelayPro
- Where
- 35 sites in United States, Japan
- Volunteers
- 110 people
- Sponsor
- Bolton Medical
Aortic Dissection, Thrombosis in Left Atrium and Right Axillary Artery
Multi-detector Computer Tomography Protocol Project: Chest Imaging Technique and Case Presentation
Multi-detector computer tomography protocol project: Chest imaging technique and case presentation.
- Conditions
- Aortic Dissection, Thrombosis in Left Atrium and Right Axillary Artery, Double IVC, May-Thurner Syndrome
- Trial name
- NCT01206751
- Testing
- Chest imaging technique and case presentation
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Taipei Medical University WanFang Hospital
Aortic Aneurysm, Thoracic
The Aortic Surgery Cerebral Protection Evaluation (ACE) Randomized CardioLink-3 Trial
The ACE trial is a multicentre, randomized controlled trial comparing axillary vs. innominate artery cannulation for established antegrade cerebral perfusion in patients having aortic surgery (thoracic and aortic arch) requiring…
- Trial name
- NCT02554032
- Testing
- Axillary artery cannulation, Innominate artery cannulation
- Where
- 2 sites in Canada
- Volunteers
- 110 people
- Sponsor
- Unity Health Toronto
Aortic Diseases, Aortic Dissection
Proximal Aortopathy in Scotland - Epidemiology and Surgical Outcomes
The aorta is the principal arterial vessel arising from the left heart that transfers blood to the body. Certain genetic and familial disease processes are known to weaken the aortic wall resulting in dilation and potential…
- Conditions
- Aortic Diseases, Aortic Dissection, Aortic Aneurysm, Thoracic, Aortic Ectasia
- Trial name
- NCT05389865
- Testing
- Surgery on the proximal aorta (aortic root +/- ascending aorta), Patients diagnosed with thoracic aortopathy but not operated upon
- Where
- United Kingdom
- Volunteers
- 1,662 people
- Sponsor
- Golden Jubilee National Hospital
Aortic Diseases, Aortic Aneurysm
LANDMARC Study: a Study With Focus on Aorta Ascendens
Rationale: Aortic diameter is currently used as a gold standard in international guidelines for prediction of aorta pathology (aortic aneurysm and aortic dissection).
- Conditions
- Aortic Diseases, Aortic Aneurysm, Aortic Dissection, Aortic Aneurysm, Thoracic
- Trial name
- NCT05655767
- Testing
- 4D-flow MR & CT-scan
- Where
- Netherlands
- Volunteers
- 65 people
- Sponsor
- Maastricht University Medical Center
Thoracic Aortic Aneurysm, Penetrating Aortic Ulcer
Zenith Thoracic Alpha (ZTA) Post-Market Data Collection
This study aims to gather real-world clinical data demonstrating the continued safety and performance of the a marketed stent graft (Zenith® Alpha Thoracic Endovascular Graft [ZTA]) and collect longer term follow-up to better…
- Trial name
- NCT06094127
- Testing
- Endovascular aortic treatment
- Where
- 10 sites in France, Germany and 2 more
- Volunteers
- 300 people
- Sponsor
- Cook Research Incorporated
Aortic Aneurysm, Thoracic
VALIANT CAPTIVIA Post-market Registry
The Valiant Thoracic Stent Graft has been preloaded on the new Captivia Delivery System (Captivia). This new delivery system was CE marked on September 14th, 2009 and was commercially released in the European Union on October…
- Trial name
- VCOUS (NCT01181947)
- Testing
- TEVAR
- Where
- 15 sites in Austria, Germany and 5 more
- Volunteers
- 100 people
- Sponsor
- Medtronic Cardiovascular
Dissection of Thoracic Aorta
Prevention of Acute Kidney Injury by Erythropoietin in Thoracic Aorta Surgery With Hypothermic Cardiac Arrest
During thoracic aortic surgery, hypothermic cardiac arrest causes aortic ischemia and reperfusion (IR) periods, respectively. Aortic ischemia results in an ischemic insult to the lower extremities and successive reperfusion…
- Trial name
- NCT01369732
- Testing
- recombinant human erythropoietin, saline
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Yonsei University
Aortic Aneurysm, Abdominal, Thoracic Aneurysm
Clinical Outcomes and Radiation Safety After Endovascular Repair of Complex AAAs Using Fenestrated- Branched Devices
The purpose of this study is to assess the clinical outcomes and radiation of the use of off-the-shelf and custom-made devices (CMDs) for the endovascular repair of juxtarenal, suprarenal, thoracoabdominal and arch aortic…
- Trial name
- NCT02266719
- Testing
- Fenestrated CMD, Type I - III TAAA, Arch cohort
- Where
- 4 sites in United States
- Volunteers
- 750 people
- Sponsor
- Carlos Timaran
Systemic Inflammatory Response Syndrome, Infections
AOrtic Surgery: Systemic Inflammatory Response Versus Sepsis
The goal of the prospective observational study is to evaluate the immunological background of inflammatory response often seen after open thoracic aortic surgery.
- Conditions
- Systemic Inflammatory Response Syndrome, Infections, Thoracic Aortic Aneurysm, Aortic Diseases
- Trial name
- AOSIS (NCT06028789)
- Testing
- Blood sample test, Thoracic Aortic Surgery
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- University Hospital Hradec Kralove
Solitary Pulmonary Nodules, Multiple Pulmonary Nodules
Extracolonic Findings on Computed Tomography (CT) Colonography
The ACRIN 7151 trial will use medical records abstraction data from participants with extracolonic findings (ECFs) reported from the ACRIN 6664 National CT Colonography Trial to: 1) measure incidence of diagnostic imaging…
- Conditions
- Solitary Pulmonary Nodules, Multiple Pulmonary Nodules, Renal Neoplasms, Adrenal Gland Neoplasms
- Trial name
- ACRIN7151 (NCT01465425)
- Volunteers
- 520 people
- Sponsor
- American College of Radiology Imaging Network
Thoracic Aortic Aneurysm, Thoracic Aorta Injury
CTAG Dissection/Trauma Post Marketing Surveillance Japan
Post Marketing Surveillance of the Conformable GORE® TAG® Thoracic Endoprosthesis
- Conditions
- Thoracic Aortic Aneurysm, Thoracic Aorta Injury, Thoracic Aortic Dissection
- Trial name
- NCT05414318
- Testing
- Conformable GORE® TAG® Thoracic Endoprosthesis
- Volunteers
- 55 people
- Sponsor
- W.L.Gore & Associates
Aorta Dissection, Aorta Aneurysm
Hybrid Operation in Thoracic Aortic Dissection
The purpose of this study is to investigate the short to mid term efficacy and safety of different hybrid operations who had complex aortic lesions, such as ascending aortic/arch aneurysm, pseudo-aneurysm, Stanford Type A…
- Trial name
- NCT01500395
- Testing
- Hybrid operation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xijing Hospital
Chest Pain, Acute Coronary Syndrome
Diagnostic Accuracy of Multislice CT Angiography for Acute Chest Pain
The ACUTE CT trial is designed to test whether the assessment of chest structures by high-resolution multislice computed tomography (CT) provides equivalent diagnostic accuracy for patient with acute chest pain or other potential…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Pulmonary Embolism, Aortic Dissection
- Trial name
- ACUTE CT (NCT00855231)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Washington
Aortic Aneurysm and Dissection, Thoracic Endovascular Aortic Repair
Pulmonary Complications Following TEVAR
The goal of this observational study is to analyze pulmonary complications after TEVAR procedures and to identify the risk factors associated with these complications.
- Trial name
- RESPIRATEVAR (NCT07863453)
- Where
- 3 sites in Italy
- Volunteers
- 385 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico