Clinical trials: Thoracic Epidural Injection
Pain, Postoperative
Erector Spinae Plane Block (ESP) Versus Thoracic Epidural Anesthesia in Video-Assisted Thoracoscopic Surgery (VATS) in Pediatric Population; a Randomized, Controlled Study
Aim of the study is to investigate the efficacy and safety of continuous ESP block in children under the age of 10 yrs undergoing video-assisted thoracoscopic procedures, compared to Thoracic Epidural Anesthesia (TEA).
- Trial name
- ESP (NCT04878341)
- Testing
- Erector Spinae Plane Block
- Where
- Italy
- Volunteers
- 74 people
- Sponsor
- Vittore Buzzi Children's Hospital
Surgery, Analgesia
Thoracic Epidural Analgesia vs Surgical Site Infiltration With Liposomal Bupivacaine Following Open Gynecologic Surgery
The goal of this study is to test the hypothesis that surgical site infiltration with liposomal bupivacaine (LB) is non-inferior to and more cost effective than thoracic epidural analgesia (TEA) for patients undergoing open…
- Trial name
- NCT04117074
- Testing
- Liposomal bupivacaine, Thoracic epidural analgesia (bupivacaine)
- Where
- United States
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Thoracic Surgery
Continuous Erector Spinae Block Versus Thoracic Epidural Analgesia for the Prevention of Chronic Pain Following Thoracotomy: a Retrospective Study
Post-thoracotomy pain syndrome (PTPS) is a prevalent complication that significantly impacts patients' quality of life, with reported incidence ranging from 25% to 90%.
- Trial name
- NCT07677540
- Testing
- ESP block, Thoracic epidural
- Where
- Israel
- Volunteers
- 34 people
- Sponsor
- Meir Medical Center
Erector Spinae Muscle Plane Block, Serratus Anterior Muscle Plane Block
Analgesic Non Inferiority of the Thoracic Bi-block in Comparison With Thoracic Epidural for VATS.
Video-Assisted thoracic surgery (VATS) is the standard treatment for localized lung cancer. However, there is no consensus on analgesic management in patients undergoing VATS.
- Conditions
- Erector Spinae Muscle Plane Block, Serratus Anterior Muscle Plane Block, Video-Assisted Thoracic Surgery, Lung Cancer
- Trial name
- ANESSTEVATS (NCT04538235)
- Testing
- Thoracic Regional Analgesia
- Where
- France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Montpellier
Anesthesia, Radical Mastectomy
Analgesic Efficacy of Ultrasound Guided Serratus Anterior Plane Block and Pectoral Nerve Block II
Modified Radical Mastectomy accounts for 31% of all breast surgeries and considered the fundamental surgical management for breast cancer. Nearly 40-60% of patients experience severe acute postoperative pain.
- Trial name
- NCT06188156
- Testing
- Anethesia
- Where
- Egypt
- Volunteers
- 99 people
- Sponsor
- Al-Azhar University
Rib Fractures, Pain, Acute
A Retrospective Review of Rib Fracture Pain Management at a London Major Trauma Centre
Thoracic epidural analgesia (TEA) is widely considered to be the current gold standard treatment for rib fracture pain and is used in the Imperial invasive treatment pathway for rib fractures.
- Trial name
- NCT04863807
- Testing
- Regional Anaesthesia
- Where
- United Kingdom
- Volunteers
- 389 people
- Sponsor
- Imperial College Healthcare NHS Trust
Pulmonary Surgery
Erector Spinae Block, Epidural Analgesia and Intrathecal Analgesia in Thoracic Surgery
Pulmonary thoracic surgery is often responsible for severe postoperative pain, which is associated with an increase in postoperative morbidity and mortality.
- Trial name
- SPIRIT (NCT04147754)
- Testing
- Epidural anesthesia, Intrathecal morphine, Erector spinae block
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Angers
Pulmonary Function
Post-operative Pulmonary Function After Kidney Surgery Under Two Different Techniques
To assess the respiratory and analgesic effects of continuous thoracic paravertebral block versus thoracic epidural in patients undergoing kidney surgery
- Trial name
- NCT03885583
- Testing
- thoracic epidural block, paravertebral block
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Assiut University
First-attempt Success Rate of Real-time Ultrasound-guided Thoracic Epidural Catheter Placement
Application of Real-time Ultrasound Guidance in Thoracic Epidural Catheter Placement
The goal of this clinical trial is to assess the success rate of real-time ultrasound-guided thoracic epidural catheter placement at the first attempt in patients who will undergo thoracic or abdominal surgeries.
- Trial name
- NCT07100769
- Testing
- Real-time ultrasound-guided thoracic epidural placement
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- University Medical Center Ho Chi Minh City (UMC)
Duodenal Neoplasm, Pancreatic Neoplasm
Rectus Sheath Block With Liposomal Bupivacaine Versus Thoracic Epidural Analgesia for Pain Control Following Pancreatoduodenectomy
This phase II trial compares the effect of rectus sheath block with liposomal bupivacaine to thoracic epidural analgesia (TEA) on pain control in patients following surgical removal of all or part of the pancreas and duodenectomy…
- Trial name
- NCT06411795
- Testing
- Bupivacaine, Hydromorphone, Iopamidol
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- Masonic Cancer Center, University of Minnesota
Analgesia, Epidural, Surgery
Ultrasound Determination of Needle Depth in Epidurals in Adult Patients
The introduction of local anesthetics and other medications into the epidural space is a principal technique in provision of anesthesia in many procedures.
- Trial name
- NCT00981916
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- University of Chicago
Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS)
Analgesic Effectiveness of SPSIPB Versus Thoracic Epidural and Systemic Opioid Analgesia After VATS (SPSIPB-VATS)
This prospective observational study aims to compare the postoperative analgesic effectiveness of three commonly used pain management strategies in video-assisted thoracoscopic surgery (VATS): Serratus Posterior Superior…
- Conditions
- Postoperative Pain Management, Video-assisted Thoracoscopic Surgery (VATS), Thoracic Epidural Analgesia, Serratus Posterior Superior Intercostal Plane Block
- Trial name
- SPSIPB-VATS (NCT07238348)
- Volunteers
- 120 people
- Sponsor
- Karadeniz Technical University
Coronary Artery Occlusion
Neuroaxial Prophylaxis for CABG
Investigators plan to study the effect of thoracic epidural analgesia on postoperative parameters (complication rate, duration of hospitalization, mortality, etc.) of coronary artery bypass grafting.
- Trial name
- NCT04244435
- Testing
- CABG, thoracic epidural analgesia, analgesia of opioids
- Where
- Russia
- Volunteers
- 300 people
- Sponsor
- Volgograd State Medical University
Thoracic Epidural
Effects of Fixation Technique On Thoracic Epidural Catheter Displacement
The purpose of our study is to assess the effectiveness of Dermabond as a thoracic epidural fixation technique compared to both Mastisol and the Grip-Lok fixation bandage, two common, widely used techniques for epidural fixation.
- Trial name
- NCT03976154
- Testing
- Thoracic Epidural Catheter Fixation Techniques
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- University of Utah
Anesthesia, Epidural, Paraesthesia
Safety of Two Epidural Catheters in Thoracic Epidural Anaesthesia (TEA)
Primary Objective: The primary objective is to demonstrate that the safety of Perifix New is non-inferior to using Perifix Standard when applied for thoracic epidural anaesthesia.
- Trial name
- NCT00394459
- Testing
- Perifix Epidural Anaesthesia Catheter, Perifix Standard, Perifix New
- Where
- Netherlands
- Volunteers
- 140 people
- Sponsor
- Maastricht University Medical Center
Malignant Neoplasm of Abdomen, Surgery
TAP Versus Thoracic Epidural in Major Abdominal Resections
The purpose of this study is to compare two standard methods of pain control management used at Spectrum Health for patients undergoing major surgery. The two methods being compared are the thoracic epidural and the TAP block.
- Trial name
- NCT02197988
- Testing
- Exparel 1.33% (20ml Volume), 0.125% bupivicaine with 2 mcg/ml Fentanyl.
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Corewell Health West
Pain
Insertion Distance of Thoracic Epidural Catheters in the Context of Thoracotomy Procedures.
This study is designed to compare thoracic epidural catheter insertion distances, in order to determine which is the best for pain relief following a thoracotomy. HYPOTHESIS : 1.
- Trial name
- NCT00754195
- Testing
- Thoracic epidural catheter
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pain, Postoperative, Oxidative Stress
Dexmedetomidine and Dexamethasone as an Adjuvant to Ropivacaine in Thoracic Surgery
The aim of the study is to investigate the effect of preoperative epidural dexmedetomidine compared to dexamethasone on postoperative pain control, analgesic consumption and oxydative stress response in patients undergoing…
- Trial name
- NCT03632460
- Testing
- Dexmedetomidine Injection [Precedex]
- Where
- Croatia
- Volunteers
- 60 people
- Sponsor
- University Hospital Dubrava
Erector Spinae Plane Block, Thoracic Epidural Analgesia
Ultrasound-guided Continuous Erector Spinae Plane Block Versus Thoracic Epidural Analgesia in Open Nephrectomy
There are different case studies about the use of erector spinae block (ESPB ) in nephrectomy, but there are no enough randomized controlled studies about it until now so it will be one of the earliest studies that investigate…
- Conditions
- Erector Spinae Plane Block, Thoracic Epidural Analgesia, Nephrectomy
- Trial name
- NCT04947644
- Testing
- Thoracic epidural analgesia, Ultrasound guided continuous erector spinae plane block
- Where
- Egypt
- Volunteers
- 54 people
- Sponsor
- National Cancer Institute, Egypt
Pneumothorax, Primary Spontaneous, VATS
Optimal Postoperative Chest Tube and Pain Management in Patients Surgically Treated for Primary Spontaneous Pneumothorax (Pneumotrial)
Guidelines lack high quality evidence on optimal postoperative chest tube and pain management after surgery for primary spontaneous pneumothorax (PSP).
- Conditions
- Pneumothorax, Primary Spontaneous, VATS, Pain, Postoperative, Locoregional Anaesthesia
- Trial name
- NCT06053476
- Testing
- Thoracic epidural analgesia, Single-shot paravertebral block, Late chest tube removal
- Where
- Netherlands
- Volunteers
- 366 people
- Sponsor
- Maxima Medical Center