Clinical trials: Thoracic Surgical Procedures
Postoperative Pain
Does ESPB Improve Postoperative Quality of Recovery After VATS
Video-Assisted Thoracoscopic Surgery (VATS) is a minimally invasive surgery. Despite reduced surgical trauma compared to the traditional thoracotomy approach, pain control after VATS remains challenging.
- Trial name
- NCT03756987
- Testing
- Ropivacaine Injection, Normal saline
- Where
- China
- Volunteers
- 76 people
- Sponsor
- Fujian Provincial Hospital
Lung Cancer, Non-Small Cell
Study to Test the Efficacy of the Vaccine GSK 249553 in Treating Non-small-cell Lung Cancer After Tumour Removal by Surgery
Patients will receive injections of GSK 249553 vaccine . Appropriate tests will be performed to assess the safety of the treatment and its ability to induce an immune response.
- Trial name
- NCT00290355
- Testing
- GSK 249553 vaccine
- Where
- 62 sites in Belgium, Estonia and 12 more
- Volunteers
- 182 people
- Sponsor
- GlaxoSmithKline
Video-assisted Thoracic Surgery, Lung Cancer
Mixed Reality Technique Combined With 3D Printing Navigational Template for Localizing Pulmonary Nodules
This study evaluates the viability and accuracy of preoperative mixed reality technique combined with three-dimensional printing navigational template guided localizing pulmonary small nodules.
- Conditions
- Video-assisted Thoracic Surgery, Lung Cancer, Pulmonary Nodule, Solitary, Pulmonary Nodule, Multiple
- Trial name
- MR&3D Local (NCT04552054)
- Testing
- Mixed Reality+ 3D printing guided localization, Computerized Tomography guided localization
- Where
- China
- Volunteers
- 136 people
- Sponsor
- Wen-zhao ZHONG
Thoracic Surgery, Anesthesia
Cerebral Oximetry-Guided Low FiO2 Strategies in Thoracic Surgery.
Brief Summary (Kısa Özet)The purpose of this study is to evaluate the safety and efficacy of a cerebral oximetry-guided low fraction of inspired oxygen (FiO_2) ventilation strategy compared to a standard high FiO_2 strategy in…
- Trial name
- NCT07659483
- Testing
- Standard High $FiO_2$ Strategy, Guided Low $FiO_2$ Strategy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Dicle University
Lung Diseases
Erector Spinae Plane Block or Serratus Anterior Plane (SAP) Block Following Video Assisted Thoracic Surgery
Video assisted thoracic surgery (VATS) has recently been evaluated as the standard surgical procedure for lung surgery. Although VATS is less painful than thoracotomy, patients may feel severe pain during the first hours at…
- Trial name
- NCT03960762
- Testing
- ESP block (Group ESP), SAP block (Group SAP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Intubation; Difficult, Intubation Complication
McGrath Series 5 Videolaryngoscope for Double-lumen Tube Intubation
1. Double-lumen tube intubation is difficult, compared with single lume tube. 2. McGrath Series 5 videolaryngoscope hase been used in difficult airway management, both in anesthetized and awake patients. 3.
- Trial name
- NCT01984970
- Testing
- videolaryngoscope
- Where
- China
- Volunteers
- 43 people
- Sponsor
- Huazhong University of Science and Technology
Thoracic, Colorectal Disorders
Evaluating Intuitive 3D Models in Preoperative Surgical Planning for Thoracic and Colorectal Procedures.
The Study Objective: To evaluate the clinical utility of a 3D model with 2D CT/MRI scans during simulated preoperative surgical planning of open, laparoscopic, or robotic-assisted anatomic lung resection (segmentectomy…
- Trial name
- ISI-I3DM-01 (NCT06434727)
- Testing
- observational study
- Where
- 4 sites in United States
- Volunteers
- 80 people
- Sponsor
- Intuitive Surgical
Video Assisted Thoracic Surgery (VATS), Non-Small Cell Lung Cancer (NSCLC)
Comparison of Two Techniques of Uniportal VATS Lobectomies for Clinical Stage I Non-Small Cell Lung Cancer
Aim of the study is to compare safety and tolerance of two techniques of Video Assisted Thoracic Surgery (VATS) uniportal lobectomies in the prospective randomized single-institutional trial.
- Trial name
- NCT03997799
- Testing
- uniportal lobectomy with complete lymphadenectomy
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- Pulmonary Hospital Zakopane
Thoracic Surgery
Evaluation of a Rehabilitation Program After Lung Surgery
Fast track programs, multimodal therapy strategies, have been introduced in many surgical fields to minimize postoperative morbidity and mortality.
- Trial name
- NCT00969358
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hopital Foch
Rehabilitation, Thoracic Surgery
Effect of High-intensity Training on the Level of Physical Activity After Thoracoscopy Surgery: a Pilot Study
Goal of this study is to evaluate management with high intensity re-entrainment during the postoperative hospital phase. This type of early treatment with as little intervention time has so far never been done.
- Conditions
- Rehabilitation, Thoracic Surgery, Physical Activity
- Trial name
- HITAT (NCT03734276)
- Testing
- High intensity activity, control arm
- Volunteers
- 30 people
- Sponsor
- Haute Ecole de Santé Vaud
Thoracic Surgery, Video-Assisted, Chewing Gum
Effect of Gum Chewing on Sore Throat After Double-lumen Tube Intubation
Patients undergoing video-assisted thoracoscopic surgery requiring double-lumen tube intubation are randomized into two groups; gum group and control group.
- Conditions
- Thoracic Surgery, Video-Assisted, Chewing Gum, Pharyngeal Diseases
- Trial name
- NCT06061250
- Testing
- Chewing a piece of gum (Xylitol gum, LOTTE WELLFOOD, Korea) before induction of anesthesia
- Sponsor
- Seoul National University Hospital
Lung Cancer
Ketamine In Thoracic Surgery (KITS) Trial
The primary aim of the study is to demonstrate a reduction in circulating interleukin 6 levels at 4 and 24 hours after completion of lobectomy (either VATS or open).
- Trial name
- KITS (NCT00504725)
- Testing
- Ketamine, 0.9% saline
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Duke University
Thoracic Surgery, Surgery, Thoracic
Sleep and Activity Monitoring After Thoracic Surgery
Show by collecting sleep and activity data, outcomes after thoracic surgery are improved with better sleep and increased activity.
- Trial name
- NCT02927860
- Testing
- Fitbit
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mayo Clinic
Videoassisted Thoracoscopic Surgery,One-lung Ventilation
The Application of Lung Ultrasound Combine With Diaphragm Ultrasound During Thoracic Surgery
Perioperative lung-protective strategies had been advocated in one-lung ventilation but normal respiratory functions were yet impacted during videoassisted thoracoscopic(VATS) surgery.
- Trial name
- NCT03802968
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hypothermia, Thoracic Neoplasm
Evaluation of the Reliability of Oesophageal Temperature in THOracic Surgery
Controlling hypothermia is essential in anesthesia to limit postoperative complications. Temperature monitoring is therefore essential.
- Conditions
- Hypothermia, Thoracic Neoplasm, Anesthesia
- Trial name
- ThoTem (NCT03903991)
- Testing
- Temperature recording
- Where
- 2 sites in France
- Volunteers
- 51 people
- Sponsor
- University Hospital, Tours
Elastofibroma Dorsi
Elastofibroma Dorsi: Clinical Features, Surgical Outcomes, and Risk Factors
This study aims to retrospectively evaluate patients who underwent surgical treatment for elastofibroma dorsi, a rare benign tumor typically located in the subscapular region of the chest wall.
- Trial name
- NCT07010224
- Testing
- Retrospective Medical Record Review
- Volunteers
- 102 people
- Sponsor
- Ondokuz Mayıs University
Lung Resection
Use of a Pressurized Face Mask for Preventing Respiratory Complications After Chest Surgery
Evaluation of efficacy and safety from 6hours of 7 cmH2O CPAP after weaning in patients undergoing lung resection, on the prevention of atelectasis / pneumonia and gas exchange improve.
- Trial name
- NCT02771327
- Testing
- CPAP plus Gas, ventimask plus gas
- Where
- 4 sites in Spain
- Volunteers
- 258 people
- Sponsor
- Hospital General Universitario Gregorio Marañon
Lung Cancer
Effectiveness of a Preoperative Pulmonary Rehabilitation Program in Patients Awaiting Lung Resection
The purpose of this study is to establish the effectiveness of a preoperative pulmonary rehabilitation program in patients awaiting lung resection for lung cancer by Video-assisted thoracic surgery in order to improve exercise…
- Trial name
- NCT01963923
- Testing
- Pulmonary Rehabilitation Program
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidade da Coruña
Thoracic Surgery
The Effect of Permissive Hypercapnia on Oxygenation and Post-operative Pulmonary Complication During One-lung Ventilation
Permissive hypercapnia increased the survival rate in patients with acute respiratory distress syndrome (ARDS) who required mechanical ventilation in critical care medicine.
- Trial name
- NCT04175379
- Testing
- group 40, group 50, group 60
- Where
- South Korea
- Volunteers
- 279 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Toraco Abdominal Aneurysm
Clinical Study on the Prevention of Surgical Wound Complications for Aneurysmal Thoracic-abdominal Aortic Pathology Using the "PREVENA" System
The patients will be randomized into two groups of 100 subjects each one. One arm will be randomized to treatment with a negative topical pressure system (Sistema Prevena ™); while the other arm ("control group") will be…
- Trial name
- TVAC (NCT03512470)
- Testing
- Sistema Prevena ™(TVAC), Standard medication
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele