Clinical trials: Thoracic Trauma
Heart Injuries, Kidney Transplant; Complications
Perioperative Factors and Early Postoperative Kidney Graft Function Recovery
Divided into two groups based on acute kidney injury: non-acute kidney injury group vs. non-acute kidney injury group. Acute kidney injury group, Acute Kidney Injury Network (AKIN), Risk, Injury, Failure, Loss of kidney function…
- Trial name
- NCT06280898
- Testing
- Remote ischemic conditioning
- Where
- South Korea
- Volunteers
- 539 people
- Sponsor
- Seoul St. Mary's Hospital
Lung Injury, Remote Ischemic Preconditioning
Remote Ischemic Preconditioning on Pulmonary Injury in Cardic Surgery
During cardiac surgery with cardiopulmonary bypass , pulmonary dysfunction remains to be a problem complicating the postoperative course of the patients.Remote ischemic preconditioning(RIPC) with transient upper limb…
- Trial name
- NCT03016182
- Testing
- Remote Ischemic Preconditioning, Control
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Xuzhou Medical University
Rib Fractures
Pain Relief for Ventilated Patients With Multiple Rib Fractures Using the ON-Q Pain Relief System
The purpose of this study is to find out if patients having the ON-Q post-op Pain Relief System for pain management of multiple rib fractures will require fewer ventilator days, and will need less IV pain medicine to control…
- Trial name
- ON-Q (NCT00880529)
- Testing
- ON-Q bupivicaine administration, IV opioid administration
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- The Cooper Health System
Thoracic Anesthesia, One Lung Ventillation (OLV)
Association Between One Lung Ventilation and Myocardial Injury Markers (Troponin T and I) in Thoracic Surgical Procedures (OLVTIS)
This prospective single-group cohort study aims to investigate the association between the One-Lung Ventilation (OLV) technique and myocardial injury, as measured by postoperative Troponin T and Troponin I levels, in patients…
- Trial name
- OLVTIS (NCT07302243)
- Where
- Indonesia
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Universitas Jenderal Soedirman
Lung Injury
Acute Lung Injury After Aortic Valve Surgery
The purpose of this prospective, randomized clinical trial is to understand and measure lung injuries caused by CPB in aortic valve surgery.
- Trial name
- NCT01184313
- Testing
- aortic valve surgery with CPB
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Oulu
Spinal Cord Injuries, Spinal Cord Diseases
Stimulation With Wire Leads to Restore Cough
The purpose of this trial is to determine the efficacy of spinal cord stimulation, using wire leads, to produce an effective cough in patients with spinal cord injuries.
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases
- Trial name
- NCT01659541
- Testing
- Expiratory muscle stimulator, Implantation of device
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- MetroHealth Medical Center
Gender Dysphoria
Effect of Nitropaste in Chest Masculinizing Surgery
Nitropaste is a topical agent that contains 2% nitroglycerin. It is an effective vascular smooth dilator, with more powerful effect on venous vasculature than arterial vasculature.
- Trial name
- NCT06428669
- Testing
- Nitro-Bid 2 % Topical Ointment
- Where
- United States
- Volunteers
- 256 people
- Sponsor
- University of Virginia
Lung Injury
Effects of Different Ventilation Patterns on Lung Injury
In 1967, the term "respirator lung" was coined to describe the diffuse alveolar infiltrates and hyaline membranes that were found on postmortem examination of patients who had undergone mechanical ventilation.This mechanical…
- Trial name
- NCT03960853
- Testing
- pressure-controlled ventilation-volume guaranteed, volume controlled ventilation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Sixth Affiliated Hospital, Sun Yat-sen University
Atrial Fibrillation, Postoperative, Postoperative Complications
Transcutaneous Autonomic Modulation in Thoracic Surgery
In this study, the investigators aim to determine whether non-invasive autonomic modulation decreases inflammation and complications after thoracic surgery.
- Conditions
- Atrial Fibrillation, Postoperative, Postoperative Complications, Inflammation
- Trial name
- TON-POINTS (NCT02783157)
- Testing
- Transcutaneous Low-Level Vagal Nerve Stimulation (LLVNS)
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Duke University
COVID-19, Lung Injury
Clinical Trial to Evaluate Methylprednisolone Pulses and Tacrolimus in Patients With COVID-19 Lung Injury
The primary objective of the study is to evaluate the days until reaching clinical stability after starting randomization in hospitalized patients with elevated inflammatory parameters and severe COVID-19 lung injury.
- Trial name
- TACROVID (NCT04341038)
- Testing
- Tacrolimus, Methylprednisolone
- Where
- Spain
- Volunteers
- 84 people
- Sponsor
- Hospital Universitari de Bellvitge
Lung Non-Small Cell Carcinoma, GastroEsophageal Cancer
Imaging and Blood-Based Biomarkers for the Evaluation of Early Signs of Myocardial Injury After Thoracic Radiation Therapy
This study assesses for early signs of damage to the heart following chest radiation therapy using both imaging (cardiac magnetic resonance imaging and cardiac positron emission tomography) and changes in blood biomarkers.
- Conditions
- Lung Non-Small Cell Carcinoma, GastroEsophageal Cancer, Esophagus Cancer
- Trial name
- NCT05717998
- Testing
- Biospecimen Collection, Computed Tomography, Magnetic Resonance Imaging of the Heart
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Ohio State University Comprehensive Cancer Center
Lung Neoplasms, Radiation Pneumonitis
Application of 4DCT-Based Pulmonary Ventilation Imaging in Lung Cancer Radiotherapy
This retrospective single-center study investigates whether four-dimensional CT (4DCT)-based lung ventilation imaging can guide functional lung avoidance radiotherapy (FLAR) for patients with primary lung cancer.
- Trial name
- FLAR-4DCT (NCT07312682)
- Where
- China
- Volunteers
- 202 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Pain, Side Effects
Comparison of IV PCA and Wound Infusion After Repair of Pectus Excavatum
Postoperative pain management is a major problem after repair of pectus excavatum.Various methods of pain management have been introduced.
- Trial name
- NCT01908491
- Testing
- IV PCA, Continuous wound infusion
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- The Catholic University of Korea
Acute Kidney Injury, Chronic Kidney Disease, Stage 3
The Association Between the Duration of Acute Kidney Injury and New-onset Chronic Kidney Disease After Cardiac or Thoracic Aortic Surgery
The investigators aimed to evaluate the association between the duration and stage of acute kidney injury (AKI) and the development of chronic kidney disease during postoperative three years in patients undergoing cardiac or…
- Conditions
- Acute Kidney Injury, Chronic Kidney Disease, Stage 3, Chronic Kidney Disease, Stage 5, Cardiac Surgery
- Trial name
- NCT04172103
- Where
- South Korea
- Volunteers
- 2,009 people
- Sponsor
- Seoul National University Hospital
Cardiotoxicity, Lung Cancer Stage III
Cardiotoxicity in Locally Advanced Lung Cancer Patients Treated With Chemoradiation Therapy
This observational cohort will evaluate the cardiovascular effects of chemoradiation used to treat locally advanced, non-small cell lung cancer.
- Conditions
- Cardiotoxicity, Lung Cancer Stage III, Lung Cancer Stage II, Radiation Toxicity
- Trial name
- CLARITY (NCT04305613)
- Testing
- Chemoradiation
- Where
- 8 sites in United States
- Volunteers
- 221 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Subacromial Impingement Syndrome, Exercise Addiction
Effects of Exercise or Taping on Pain, Function, Range of Motion, Strength and Kyphosis in Subacromial Pain Syndrome
Participants with subacromial pain syndrome underwent shoulder exercises. In addition to the exercises, group A received thoracic extension exercise and group B received kinesio taping.
- Conditions
- Subacromial Impingement Syndrome, Exercise Addiction, Shoulder Pain
- Trial name
- NCT06777121
- Testing
- Shoulder exercises + Thoracic extension exercise, Shoulder exercises + Thoracic kinesio taping, Shoulder exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Sevtap Günay
Lung Cancer
Pifenidone Prophylactic Therapy for Radiation Lung Injury in Patients Who Have Previously Received Immune Checkpoint Inhibitors
Patients with advanced lung cancer who have previously received immunocheckpoint inhibitor therapy, undergone chest radiation therapy again have developed radiation induced lung injury.
- Trial name
- NCT05801133
- Testing
- Pirfenidone
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Hubei Cancer Hospital
Traumatic Pneumothorax
Pigtail Catheter Versus Chest Tube in the Management of Traumatic Pneumothorax
A small 14-French(F) pigtail catheter (PC) has been shown to work equally well with traditional 32-40F chest tube (CT), especially in traumatic pneumothorax. There are no clinical data on tube-site pain.
- Trial name
- NCT01537289
- Testing
- Pigtail catheter insertion (Cook), chest tube (28-French)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Spinal Cord Injury Thoracic
The Effect of Superimposed Electrical Stimulation on Sitting Balance, Respiratory Functions, and Abdominal Muscle Thickness in Complete Spinal Cord Injury
The primary aim of the current study was to investigate the effects of SiFES (superimposed functional electrical stimulation) on sitting balance in patients with complete Spinal Cord Injury (SCI) compared to exercise alone.
- Trial name
- NCT06104982
- Testing
- NeuroTrac MyoPlus Pro single-channel electromyography biofeedback electrotherapy devices, Isometric strengthening exercises
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Ankara City Hospital Bilkent
Thoracic Injuries
Comparison of McGrath and Macintosh Laryngoscopes for Insertion of a Double Lumen Tube by Residents
The insertion of double lumen tube is difficult even more if it is a resident with no experience. we think that using videolaryngoscopes for novice ones would facilitate insertion of double lumen tube thanks to the visualization…
- Trial name
- MacGrathDES (NCT03710096)
- Testing
- macGrath, Macintosh's
- Where
- France
- Volunteers
- 148 people
- Sponsor
- University Hospital, Lille