Clinical trials: Thoracic Trauma
Coronary Artery Disease, Coronary Artery Angiography
Vitamin E and N-acetylcysteine for Preventing Contrast-Induced Acute Kidney Injury After Coronary Artery Catheterization
In a double-blinded randomized clinical trial, all patients undergoing coronary artery catheterization who will met our criteria, will be enrolled into three groups to receive either, vitamin e, n-acetylcysteine, or placebo.
- Conditions
- Coronary Artery Disease, Coronary Artery Angiography, Coronary Catheterization, Contrast-induced Nephropathy
- Trial name
- NCT03755700
- Testing
- Vitamin E, N-acetyl cysteine, Normal Saline Flush, 0.9% Injectable Solution
- Where
- Iran
- Volunteers
- 1,000 people
- Sponsor
- Rajaie Cardiovascular Medical and Research Center
Perioperative Complications, Perioperative/Postoperative Complications
Perioperative Database of Chinese Elderly Patients
The investigators aim to establish a prospective database of perioperative elderly patients from multiple regions and centers. Collected data involves postoperative complications of the central nervous system, cardiovascular…
- Conditions
- Perioperative Complications, Perioperative/Postoperative Complications, Perioperative Adverse Events
- Trial name
- PDCEP (NCT04911530)
- Testing
- no intervention
- Where
- China
- Volunteers
- 10,000 people
- Sponsor
- Chinese PLA General Hospital
Spinal Cord Injury, Spinal Cord Injury Thoracic
Investigating the Impact of Spinal Cord Electrical Stimulation Combined With Individualized Physical Therapy on Lower Extremity Function in Patients With Spinal Cord Injury
This study aims to understand the differences in the effects of two rehabilitation approaches on lower limb function recovery in patients with spinal cord injuries: 1.
- Conditions
- Spinal Cord Injury, Spinal Cord Injury Thoracic, Spinal Cord Injury/Damage, Spinal Cord Injury T1-L2
- Trial name
- NCT07037628
- Where
- Taiwan
- Volunteers
- 76 people
- Sponsor
- Lian-Cing Yan, MSPT
Thoracic Surgery, Cardiopulmonary Bypass
Protection During Cardiac Surgery.
This trial investigates whether a multimodal cardioprotection per-surgery therapeutic strategy could reduce myocardial injury in patients undergoing cardiac surgery compared to traditional management.
- Trial name
- ProCCard (NCT03230136)
- Testing
- multimodal cardioprotection strategy, standard anesthetic procedure
- Where
- 8 sites in France
- Volunteers
- 210 people
- Sponsor
- Hospices Civils de Lyon
Thorax Traumas
The Investigation of Predicting Mortality and Morbidity in Patients Admitted to Intensive Care Unit With Thoracic Trauma Using Selected Biomarkers and Parameters
This prospective study aimed to predict morbidity and mortality after thoracic trauma in intensive care unit evaluated clinical and biochemical data of 50 intensive care unit patients.
- Trial name
- NCT06930222
- Testing
- blood sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Suleyman Demirel University
Non Small Cell Lung Cancer, Small Cell Lung Cancer
Esophageal Sparing Intensity-modulated Radiation Therapy (IMRT) for Locally-Advanced Thoracic Malignancies
Hypothesis 1- Using IMRT, the radiation therapy (RT) dose can be safely escalated from 58 Gy to 74 Gy given as 6 fractions/week with concurrent chemotherapy.
- Conditions
- Non Small Cell Lung Cancer, Small Cell Lung Cancer, Thymoma, Thymus Neoplasms
- Trial name
- ESIMRT (NCT00921739)
- Testing
- Esophageal sparing IMRT
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Duke University
Surgeries Undergoing General Anesthesia
Impact of Intraoperative Oxygenation Practices on Patient Outcomes
This multicenter, cluster-randomized, cluster-crossover clinical trial evaluates the impact of three intraoperative FiO2 (Fraction of Inspired Oxygen) oxygenation strategies-lower (FiO₂ 0.21-0.40), intermediate (FiO₂ 0.40-0.80)…
- Trial name
- IntraOp Ox (NCT07224243)
- Testing
- Lower FiO2, Intermediate FiO2, Higher FiO2
- Where
- 4 sites in United States
- Volunteers
- 54,000 people
- Sponsor
- Frederic T Billings IV
Paraquat Poisoning, Lung Injury
Human Umbilical-Cord-Derived Mesenchymal Stem Cell Therapy in Paraquat Poisoning Induced Lung Injury
Phase I-II Clinical Trial-Safety and efficacy of umbilical-cord-derived mesenchymal stem cell (UC-MSC) in patients with paraquat poisoning induced lung injury, randomized,single blind, controlled prospective study.
- Trial name
- UCMSC-PQLI (NCT02444858)
- Testing
- UCMSC group, Control group(Normal saline)
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Affiliated Hospital to Academy of Military Medical Sciences
Lung Neoplasms
Effect of Remote Ischemic Preconditioning on Lung Injury After Pulmonary Resection
The purpose of this study is to determine whether ischemic preconditioning reduces lung injury in patients undergoing pulmonary resection.
- Trial name
- NCT01307085
- Testing
- remote ischemic preconditioning
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Cai Li
Pneumothorax
Lung Ultrasound Versus Chest Radiography for Detection of Pneumothorax
Sunnybrook Health Sciences Center annually provides assistance to approximately 600 cardiac surgeries and 1500 trauma patients, many of whom require chest tubes to prevent blood and fluids from accumulating in the pleural…
- Trial name
- LUSvsCXR (NCT06022081)
- Testing
- Lung ultrasound to detect pneumothorax.
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Sunnybrook Health Sciences Centre
Lung Cancer
An App to Identify Radiation Pneumonitis - a Pre-Study in Healthy Volunteers
Radiation pneumonitis is a possible side effect of radiotherapy for lung cancer. Since it often occurs only several weeks following radiotherapy, the corresponding symptoms may not be associated with previous administered…
- Trial name
- POLCAR-HV (NCT07824544)
- Testing
- PneumoCheck app
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital Schleswig-Holstein
Rib Fractures, Pain, Acute
Blue Light as an Anti-inflammatory and Analgesic Strategy in Thoracic Trauma
The main goal of this clinical trial is to learn if light therapy improves pain and inflammation in adults with painful rib fractures.
- Trial name
- BLAASTT (NCT06626334)
- Testing
- Bright Blue Light, Bright Full-Spectrum (White) Light, Usual Ambient Light
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Rebecca E Kotcher, MD
Chest Trauma, Chest Pain
Serratus Plane Block for Rib Fractures
Patients with ipsilateral multiple rib fractures will be randomized to receive either a single-shot ultrasound-guided serratus plane block, or a continuous serratus plane block within 24h from the chest trauma.
- Trial name
- NCT03664973
- Testing
- Serratus plane block
- Where
- Italy
- Sponsor
- Azienda USL Reggio Emilia - IRCCS
Unstable Angina, Coronary Artery Bypass Graft
Comparison Between Lidocaine, Dexmedetomidine, and Their Combined Infusion in Subjects Undergoing Coronary Artery Bypass Graft
The aim of the present study is to compare the antiarrhythmic and myocardial protective effect between lidocaine, dexmedetomidine, and their combined infusion in subjects undergoing coronary artery bypass graft.
- Conditions
- Unstable Angina, Coronary Artery Bypass Graft, Dexmedetomidine, Lidocaine
- Trial name
- NCT01688648
- Testing
- Lidocaine infusion, Dexmedetomidine infusion
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Samsung Medical Center
Mediastinitis, Esophageal Neoplasms
Endoscopic-vacuum Assisted Closure of Intrathoracic Postsurgical Leaks
The purpose of this study is to determine the short and long term outcome of endoscopic vacuum assisted closure of intrathoracic postsurgical leaks.
- Conditions
- Mediastinitis, Esophageal Neoplasms, Anastomotic Leakage
- Trial name
- EVACoIL (NCT00876551)
- Testing
- Endoscopic vacuum assisted closure
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- Hannover Medical School
Lung Injury, Acute, Thoracotomy
Prevention of Lung Edema After Thoracic Surgery
Background : Acute lung injury (ALI) occasionally occurs after pulmonary resection and carries a bad prognosis with a high mortality rate ranging from 20 to 100%. Objectives : 1.
- Conditions
- Lung Injury, Acute, Thoracotomy, Anesthesia, Intensive Care, Surgical
- Trial name
- NCT00498251
- Testing
- inhalation of salbutamol (5 mg), ipratropium
- Where
- Switzerland
- Volunteers
- 30 people
- Sponsor
- University Hospital, Geneva
Thoracic Fracture
Effect of Positive Expiratory Pressure on the Management of Chest Trauma
Chest trauma (CT) are a common problem in our environment caused mainly by traffic accidents and causal and domestic accidents among the elderly population.
- Trial name
- NCT04548466
- Testing
- PEP bottle
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Hospital de Granollers
Systemic Inflammatory Response Syndrome, Acute Kidney Injury
High Cut Off Dialysis in Systemic Inflammatory Response Syndrome Patients After Cardiac Surgery
A high cut off dialyzer (septeX) is tested in patients after cardio-thoracic surgery with incidence of "systemic inflammatory response syndrome" (SIRS) and associated increased risk for acute kidney injury (AKI).
- Trial name
- HICOSIRS (NCT01579396)
- Testing
- septeX, standard therapy
- Where
- Germany
- Sponsor
- Vantive Health LLC
Thoracic Injuries
Far Forward Battlefield Telemedicine: Evaluation of Handheld Ultrasound
The goal of this study is to improve survival of battlefield trauma through ultrasound telemedicine and remotely guided therapeutics.
- Trial name
- NCT00615979
- Testing
- Miniature echo machine
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Bleeding, Hypoxia
Video-guided Percutaneous Tracheostomy (PCT) Versus Conventional PCT: Comparing Safety and Efficacy
The purpose of this study is to compare the feasibility, safety, efficacy and ease of performance of a video-assisted PCT (via an endotracheal tube embedded with a mini video-camera) with the standard ("blind") PCT technique.
- Conditions
- Bleeding, Hypoxia, Atelectasis, Pneumothorax
- Trial name
- NCT01012518
- Testing
- Standard PCT, Video-guided PCT
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Tel-Aviv Sourasky Medical Center