Clinical trials: Thoracic Trauma
Traumatic Lung Injury
Impact of the Early Use of High Flow Nasal Cannula in Patients With Post-traumatic Lung Contusion, a Randomized Clinical Trial
Early and continuous administration of oxygen via high flow nasal cannula in patients with lung contusion and non-severe acute lung injury might reduce the incidence of intubation and hold the deterioration of pulmonary functions.
- Trial name
- NCT05509088
- Testing
- high flow nasal cannula
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Ain Shams University
Rib Fractures
Continuous Intercostal Nerve Blockade for Traumatic Rib Fractures
Rib fractures are common injuries in accident patients and can be associated with significant pain during recovery. If poorly controlled, pain from splinting due to rib fractures can result in difficulty in breathing leading to…
- Trial name
- NCT02604589
- Testing
- hydromorphone hydrochloride, Infusion catheter placement, bupivicaine 0.25%
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Anthony Iacco
Traumatic Pneumothorax and Hemothorax
Emergency Small vs Large Tube Thoracostomy in Chest Trauma Patients.
To compare between small sized tube thoracostomy and large sized tube thoracostomy regarding the need for another chest tube for the fear of obstruction (in hemomothorax) or ineffective drainage (in hemothorax, pneumothorax or…
- Trial name
- NCT04863989
- Testing
- tube thoracostomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Rib Fractures
Individualized Discharge Planning in Patients With Rib Fracture
Patients with rib fractures may develop pneumonia and even respiratory failure requiring critical care, ventilator management, and hospitalization.
- Trial name
- NCT04168996
- Testing
- Individualized discharge planning
- Where
- Spain
- Volunteers
- 81 people
- Sponsor
- Universidad de Granada
Athletic Injuries
The Effect of Thoracic Manipulation on Upper Body Stability in Basketball Athletes
Basketball is the most popular sport in the world and has become even more popular as a result of the attention it has received.
- Trial name
- NCT06410235
- Testing
- Thoracic manipulation and exercise program, exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Cachexia, Fatigue
Pulmonary Rehabilitation in Improving Lung Function in Patients With Locally Advanced Non-Small Cell Lung Cancer Undergoing Chemoradiation
This randomized clinical trial studies pulmonary rehabilitation in improving lung function in patients with locally advanced non-small cell lung cancer undergoing chemoradiation.
- Conditions
- Cachexia, Fatigue, Pulmonary Complications, Radiation Toxicity
- Trial name
- NCT02017925
- Testing
- exercise intervention, pulmonary complications management/prevention, quality-of-life assessment
- Sponsor
- Ohio State University Comprehensive Cancer Center
Thoracic Trauma, Blunt Trauma
The Predictive Value of Chest Trauma Score and Thoracic Trauma Severity Score in Thoracic Trauma Patients
The aim of this prospective study is Comparing the diagnostic accuracy of chest Trauma Score and Thoracic Trauma Severity Score in predicting morbidity and mortality.
- Trial name
- NCT07822191
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Traumatic Thoracic Acute Spinal Cord Injury
The INSPIRE Study: Probable Benefit of the Neuro-Spinal Scaffold for Treatment of AIS A Thoracic Acute Spinal Cord Injury
This is an HDE probable benefit, open-label, non- randomized, single-arm, multicenter study to evaluate the safety and probable benefit of the poly(lactic-co-glycolic acid)-b-poly(L-lysine) Scaffold ("Scaffold") in subjects with…
- Trial name
- NCT02138110
- Testing
- Neuro-Spinal Scaffold
- Where
- 8 sites in United States
- Volunteers
- 20 people
- Sponsor
- InVivo Therapeutics
Lung Injury, Preterm Birth
Positive End-Expiratory Pressure (PEEP) Levels During Resuscitation of Preterm Infants at Birth (The POLAR Trial).
Premature babies often need help immediately after birth to open their lungs to air, start breathing and keep their hearts beating.
- Trial name
- POLAR (NCT04372953)
- Testing
- Positive End-Expiratory Pressure (PEEP)
- Where
- 27 sites in United States, Australia and 5 more
- Volunteers
- 906 people
- Sponsor
- Murdoch Childrens Research Institute
Rib Fractures, Analgesia
Serratus Anterior Plane Block Versus Thoracic Paravertebral Block.
Compare between serratus anterior plane block and thoracic Paravertebral block in analgesia for patients with multiple rib fractures
- Trial name
- NCT04554186
- Testing
- Serratus anterior plane block, Thoracic Paravertebral block, Control
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Minia University
Hypotension, Kidney Injury
Evaluating Fluid Strategies in Thoracic Surgery Patients Utilizing a Goal Directed Approach
The purpose of this study is to conduct a prospective, randomized, controlled trial comparing a restrictive vs. conservative fluid strategy in thoracic surgery patients.
- Trial name
- NCT02135146
- Testing
- Plasmalyte 3ml/kg/hr group, Plasmalyte 6ml/kg/hr group
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Colorado, Denver
Acute Respiratory Distress Syndrome, Acute Lung Injury
Early Low Dose Steroid Therapy of Acute Respiratory Distress Syndrome
The purpose of this study is to determine whether the 2mg/kg administration of corticosteroids, in the form of methylprednisolone sodium succinate, in early phase acute respiratory distress syndrome after thoracic surgery, will…
- Conditions
- Acute Respiratory Distress Syndrome, Acute Lung Injury, Postoperative Complications
- Trial name
- NCT00290602
- Testing
- Methylprednisolone sodium succinate
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- National Cancer Center, Korea
Fracture Rib
Rhomboid Intercostal and Sub-Serratus Block for Improving Pulmonary Function and Pain in Patients With Fracture Ribs
Rib fractures are seen in more than 50% of patient spresenting with blunt chest trauma and are associated with significant morbidity, long-term disability and mortality .
- Trial name
- NCT05898958
- Testing
- thoracic paravertebral block, rhomboid intercostal and subserratus block
- Where
- 2 sites in Egypt
- Volunteers
- 50 people
- Sponsor
- Zagazig University
Chest Trauma, Rib Fractures
Comparing the Efficacy of Conservative Treatment With Minimally Invasive Surgery in the Treatment of Rib Fractures
Open, randomized, parallel controlled prospective clinical study design was used in this study.Subjects were patients with 2-4 displaced non-flail rib fractures.Operation group (Group 1) : minimally invasive internal fixation…
- Conditions
- Chest Trauma, Rib Fractures, Surgery--Complications
- Trial name
- NCT04541758
- Testing
- surgical treatment, Conservative treatment
- Volunteers
- 238 people
- Sponsor
- Shanghai 6th People's Hospital
Hiv, Lung Injury
Effects of Using E-Cigarettes on Lungs in People With HIV (HBS Ancillary)
This is an ancillary study, thus participants will be recruited from participants in the HBS Study. This project acutely assesses the role of the e-cigarettes and vaping on lung health.
- Trial name
- HBS Ancillary (NCT04794543)
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Pennington Biomedical Research Center
Thoracic Surgery, Cardiopulmonary Bypass
Cerebral Autoregulation Monitoring During Cardiac Surgery
Neurological complications from cardiac surgery are an important source of operative mortality, prolonged hospitalization, health care expenditure, and impaired quality of life.
- Trial name
- NCT00981474
- Testing
- blood pressure maintenance based on cerebral blood flow autoregulation measurement, Control group
- Where
- United States
- Volunteers
- 460 people
- Sponsor
- Northwestern University
Pneumothorax, Hemothorax
Evaluating Improvised Chest Drainage Techniques in Conflict Zones
This study examines the use of improvised chest drainage systems in managing chest trauma at Wad Madani Teaching Hospital, a low-resource and conflict-affected setting.
- Conditions
- Pneumothorax, Hemothorax, Thoracic Trauma, Flail Chest
- Trial name
- NCT06683976
- Where
- Sudan
- Volunteers
- 180 people
- Sponsor
- Sudan Medical Specialization Board
Nursing Education
Effectiveness of Scenario-Based Online Simulation in Chest Trauma in Nurses
Methods This randomized controlled trial evaluated teaching strategies for chest trauma education. The course was promoted via posters and conducted over two days, with two sessions per day.
- Trial name
- NCT06902870
- Testing
- Scenario-Based Online Simulation Training Program, Classroom-Based Teaching
- Where
- Taiwan
- Volunteers
- 95 people
- Sponsor
- tygh backup
Coronary Artery Disease, Coronary Artery Bypass Grafting
Comparative Outcomes of Mammary Artery Harvesting: Infection, Occlusion Rates and Thoracic Pain Assessment
The COMFORT Trial is a randomized controlled superiority trial comparing skeletonized (SK) versus non-skeletonized (non-SK) harvesting of the left internal mammary artery (LIMA) to left anterior descending artery (LAD) graft in…
- Conditions
- Coronary Artery Disease, Coronary Artery Bypass Grafting, Surgical Site Infection
- Trial name
- COMFORT (NCT07720661)
- Testing
- Skeletonized LIMA Harvesting, Non-Skeletonized LIMA Harvesting
- Sponsor
- Hamilton Health Sciences Corporation
Thoracic Outlet Syndrome, Whiplash Injuries
Whiplash-induced Thoracic Outlet Syndrome Treated With Botulinum Toxin.
Whiplash injuries following car accident are common, it has been reported to affect 83% of individuals injured in traffic collisions (Yadla S, 2007).
- Trial name
- NCT05536570
- Testing
- IncobotulinumtoxinA 100 UNT
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- King, David, MD