Clinical trials: Thoracic Trauma
Spinal Cord Injury
Phase II Randomized Pilot Study of Body Weight Support and Treadmill Training for Chronic Thoracic Spinal Cord Injury
OBJECTIVES: I. Assess the ability of patients with and without sensorimotor loss below the thoracic spinal cord injury to execute coordinated whole-limb synergies sufficient for walking with full or partial weight support. II.
- Trial name
- NCT00004812
- Testing
- Exercise
- Volunteers
- 26 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Lung Non-Squamous Non-Small Cell Carcinoma, Radiation-Induced Pneumonitis
Nintedanib Compared With Placebo in Treating Against Radiation-Induced Pneumonitis in Patients With Non-small Cell Lung Cancer That Cannot Be Removed by Surgery and Are Undergoing Chemoradiation Therapy
This trial studies the side effects and how well nintedanib works compared to a placebo in treating against radiation-induced pneumonitis (inflammation of the lungs) in patients with non-small cell lung cancer that cannot be…
- Conditions
- Lung Non-Squamous Non-Small Cell Carcinoma, Radiation-Induced Pneumonitis, Stage II Lung Non-Small Cell Cancer AJCC v7, Stage IIA Lung Non-Small Cell Carcinoma AJCC v7
- Trial name
- NCT02452463
- Testing
- Durvalumab, Nintedanib, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Roswell Park Cancer Institute
Pediatric Acute Lung Injury
Pharmacologic Impact on Sedation Assessments
PISA is an ancillary study to the NIH funded clinical RESTORE Trial (U01 HL086622). This study will provide data that may allow for improved dosing recommendations in this critically ill population of children.
- Trial name
- PISA (NCT01105663)
- Testing
- Pharmacokinetic Sampling and pharmacogenetic analysis
- Where
- United States
- Volunteers
- 175 people
- Sponsor
- Children's Hospital of Philadelphia
Impingement Shoulder
Thoracic Manipulation Versus Myofascial Release in Patients With Shoulder Impingement Syndrome
aims: • To investigate the effect of adding thoracic manipulation vs myofascial release to scapular stabilization exercise on pain intensity.
- Trial name
- NCT05104671
- Testing
- scapular stabilization exercises., Thoracic manipulation., Myofascial release.
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- manar sameh el taher
Neonatal Resuscitation, Apnea Neonatal
Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates
Many extremely premature infants require immediate help with breathing after birth. Positive pressure ventilation (PPV) using a device called a T-piece resuscitator is a common method.
- Trial name
- MVP (NCT06849596)
- Testing
- Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR)
- Where
- 11 sites in United States, Canada and 1 more
- Volunteers
- 780 people
- Sponsor
- Michelle Baczynski
Chest Trauma, Fluid Balance; Disorder
Chest Trauma :Prediction of Thoracic Injuries Clinically and Radiologically
Trauma is a major cause of morbidity and mortality worldwide. Despite the advent of specialized trauma centers the outcome of patients who sustain major trauma remains disappointing.
- Trial name
- chesttrauma (NCT03686579)
- Testing
- chest trauma
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assiut University
Shoulder Pain, Shoulder Impingement Syndrome
Thoracic Spine and Shoulder Kinematics and Muscle Activation in Rock Climbers With Shoulder Pain
Background and Purpose: Rock climbing has been a popular sport in recent years. Rock climbing includes various open-chain and closed-chain arm movements.
- Trial name
- NCT05950360
- Testing
- Electromagnetic tracking system, surface electromyography
- Where
- Taiwan
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Breast Cancer, Glioma
A Study of Gene Polymorphisms and Normal Tissue Radiation Injury in Patients Treated for Breast, Prostate, Brain, Lung, and Head and Neck Cancers
This study will examine, for the first time, the independent contribution of a patient's own genetic makeup to the development of post-radiation complications, permitting the future development of predictive tests to avoid…
- Conditions
- Breast Cancer, Glioma, Prostate Cancer, Carcinoma, Squamous Cell
- Trial name
- NCT00122239
- Where
- Canada
- Volunteers
- 13 people
- Sponsor
- AHS Cancer Control Alberta
Lung Injury
Acute Lung Injury After Aortic Valve Surgery
The purpose of this prospective, randomized clinical trial is to understand and measure lung injuries caused by CPB in aortic valve surgery.
- Trial name
- NCT01184313
- Testing
- aortic valve surgery with CPB
- Where
- Finland
- Volunteers
- 100 people
- Sponsor
- University of Oulu
Ventilator-Induced Lung Injury, Inflammatory Response
Inflammatory Local Response During OLV: Protective vs Conventional Ventilation Strategy
This study evaluates the local cytokine inflammatory response during one lung ventilation in patients undergoing pulmonary lobectomy or wedge resection.
- Conditions
- Ventilator-Induced Lung Injury, Inflammatory Response, Respiratory Complication
- Trial name
- NCT03056885
- Testing
- Conventional One-Lung Ventilation, Protective One-lung ventilation
- Volunteers
- 28 people
- Sponsor
- University of Roma La Sapienza
Depression, Anxiety
Monoamine Oxidase A PET/CT in Various MAO-A-Related Disease
To evaluate the potential usefulness of 18F-AIPF-1026 positron emission tomography/ computed tomography (PET/CT) for the diagnosis of primary and metastatic lesions in various MAO-A-related disease patients.
- Conditions
- Depression, Anxiety, Heart Injuries
- Trial name
- NCT07685860
- Testing
- Diagnostic Test: 18F-AIPFA-1026
- Where
- 3 sites in China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tianjin Medical University
Rib Fractures, Pain, Acute
Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled Trial
Blunt chest trauma is the second most common form of unintentional trauma in the US and is associated with significant morbidity and mortality. Thoracic injuries are the third most common cause of death in trauma patients.
- Trial name
- NCT05321121
- Testing
- Dexmedetomidine
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- University of California, Irvine
Breast Cancer, Colorectal Cancer
Growth Factor Levels in the Blood of Patients Undergoing Radiation Therapy for Epithelial Cancer
RATIONALE: Measuring levels of transforming growth factor-beta (TGF-beta) in the blood of patients with epithelial cancers (head and neck, lung, breast, colorectal, and prostate) may help doctors predict how patients will respond…
- Conditions
- Breast Cancer, Colorectal Cancer, Head and Neck Cancer, Lung Cancer
- Trial name
- NCT00897793
- Testing
- venipuncture, radiation therapy
- Where
- 3 sites in United States
- Volunteers
- 25 people
- Sponsor
- Vanderbilt-Ingram Cancer Center
Abdominal Injury, Thoracic Injury
Outcome of Patients With Thoraco-abdominal Injury and Stress-induced Hyperglycemia or Diabetic Hyperglycemia
This study aimed to measure the effects of SIH and DH on the mortality outcomes of the adult patients with moderate to severe thoracoabdominal injury
- Conditions
- Abdominal Injury, Thoracic Injury, Hyperglycemia, Hyperglycemia Stress
- Trial name
- NCT04058015
- Testing
- Stress-induced hyperglycemia, Diabetic hyperglycemia, Diabetic normoglycemia
- Where
- Taiwan
- Volunteers
- 802 people
- Sponsor
- Chang Gung Memorial Hospital
Spinal Cord Injuries, Spinal Cord Diseases
Spinal Cord Stimulation to Restore Cough
The purpose of this trial is to determine the efficacy of spinal cord stimulation to produce an effective cough in patients with spinal cord injuries.
- Conditions
- Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases
- Trial name
- NCT00116337
- Testing
- Spinal Cord Stimulation to restore cough, Expiratory Muscle Stimulator
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- MetroHealth Medical Center
Complex Regional Pain Syndromes
THORACIC MANIPULATION and COMPLEX REGIONAL PAIN SYNDROME
To compare the effect of combined thoracic manipulation (TM) and traditional physical therapy treatment (TPT) versus TPT treatment alone on pain severity at rest and functional disability in patients with type 1 complex regional…
- Trial name
- NCT04769128
- Testing
- Traditional physical therapy programe
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- South Valley University
Dislocation, Infection
Fixation of Thoracic Epidurals Influencing Catheter-related Infections and Dislocation
Major interest in our investigation is to find out whether distinct fixation techniques influence catheter dislocation and/ or incidence of local inflammation.
- Conditions
- Dislocation, Infection, Line Colonisation, Line Insertion Site
- Trial name
- TDPAFD (NCT01402778)
- Where
- Germany
- Volunteers
- 140 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Artificial Intelligence, Lung Diseases
Retrospective Study of Carebot AI CXR Performance in Preclinical Practice
The purpose of this study is to describe the design, methodology and evaluation of the preclinical test of Carebot AI CXR software, and to provide evidence that the investigated medical device meets user requirements in…
- Conditions
- Artificial Intelligence, Lung Diseases, Pneumothorax, Pleural Effusion
- Trial name
- NCT05594485
- Testing
- Carebot AI CXR
- Where
- Czechia
- Volunteers
- 127 people
- Sponsor
- Carebot s.r.o.
Thoracic Trauma, Blunt Trauma
The Predictive Value of Chest Trauma Score and Thoracic Trauma Severity Score in Thoracic Trauma Patients
The aim of this prospective study is Comparing the diagnostic accuracy of chest Trauma Score and Thoracic Trauma Severity Score in predicting morbidity and mortality.
- Trial name
- NCT07822191
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane