Clinical trials: Thoracolumbar
Spinal Deformity, Spinal Instability
RCT of AttraX® Putty vs. Autograft in Instrumented Posterolateral Spinal Fusion
The purpose of this study is to demonstrate the non-inferiority of AttraX® Putty as a bone graft substitute for autograft in instrumented posterolateral fusion of the thoracolumbar spine, in terms of efficacy and safety.
- Conditions
- Spinal Deformity, Spinal Instability, Instrumented Spinal Fusion
- Trial name
- AxA (NCT01982045)
- Testing
- AttraX® Putty, Autologous bone graft
- Where
- 4 sites in Netherlands
- Volunteers
- 100 people
- Sponsor
- UMC Utrecht
Spine Surgeries
Thoracolumber Oterfacial Plane Block for Spine Surgery
The most commonly used technique to anesthetize patients scheduled for thoracic or lumbar spine surgery is general anesthesia. Analgesic techniques vary from the use of neuraxial techniques like epidural, intrathecal, or caudal…
- Trial name
- TLIP (NCT03060681)
- Testing
- Bupivacaine 0.5% injected in the thoraco-lumber inetrfacial plane block
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Mansoura University
Posterior Short-segment Pedicle Instrumentation
A Modified Placement of Two Additional Pedicle Screws at the Fracture Level for the Treatment of Thoracolumbar Burst Fractures--a Study Protocol of a Randomised Controlled Trial
Controversies exist about the best treatment of burst fractures of the thoracolumbar spine. Adding screws in fractured segment has been proved in many literatures that can improve construct stiffness but sometimes aggravate the…
- Trial name
- NCT03384368
- Testing
- fractured level screws-distraction
- Where
- China
- Volunteers
- 70 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Chronic Non Specific Mechanical Low Back Pain
Effect of Lumbar Stabilization Exercises With and Without YTWL (Scapular Stabilization Exercises) on Reducing Chronic Low Back Pain and Related Disability by Numerical Pain Rating Scale and Modified Oswestry Disability Index Respectively.
Chronic low back pain is a common problem that can make daily activities difficult. Exercises that strengthen and stabilize the lower back are commonly used to reduce pain and improve movement.
- Trial name
- A RCT (NCT07845760)
- Testing
- Lumbar Stabilization Exercises and heating pad, Scapular Stabilization Exercises (YTWL) + Lumbar Stabilization Exercises + Heating Pad
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Dow University of Health Sciences
Osteoporotic Fracture of Vertebra
Safety and Efficacy of the ISS Sleeve Augmentation Technique in the Treatment of Thoracolumbar Osteopenic Fractures
Implant anchorage is difficult in patient with osteoporotic bone. To improve the implant bone interface, the ISS stabilization system has been developed.
- Trial name
- NCT04495439
- Testing
- Augmentation with the ISS Study System, Augmentation with PMMA
- Where
- Austria
- Volunteers
- 2 people
- Sponsor
- Nexilis AG
Pregnant Women, First Pregnancy
Biomechanical and Viscoelastic Properties of Thoracolumbar Fascia in Pregnant Women
Pregnancy causes the development of biomechanical adaptations in the musculoskeletal system, especially in the lumbopelvic region.
- Trial name
- NCT05335330
- Testing
- Evaluation of biomechanics and viscoelastic properties of Thoracolumbar fascia
- Where
- Turkey (Türkiye)
- Volunteers
- 145 people, healthy volunteers welcome
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Postoperative Pain After Spinal Surgery
Modified Thoracolumbar Interfascial Plane Block vs Retrolaminar Block for Pain in Lumbar Spine Surgeries
This prospective randomized double-blind study aims to compare the efficacy of modified Thoracolumbar Interfascial Plane (mTLIP) block versus Retrolaminar block for postoperative pain control in patients undergoing elective…
- Trial name
- NCT07883616
- Testing
- Morphine, Bupivacaine, Dexamethasone
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Zagazig University
Lumbar Disc Herniation
Comparison of Ultrasound-Guided Classic And Lateral Approach Thoracolumbar Interfascial Plane Block
US-guided peripheral nerve blocks have been used increasingly due to the advantages of ultrasound in anesthesia practice. TLIP block is one of these nerve blocks performed under US guidance.
- Trial name
- NCT03854240
- Testing
- Classic block (Group C) and modified block (Group M) groups
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Degenerative Disc Disease, Spondylolisthesis
The European Robotic Spinal Instrumentation (EUROSPIN) Study
In a multinational prospective study, preoperative, intraoperative, perioperative and follow-up data on patients receiving thoracolumbar pedicle screw placement for degenerative disease or infections or tumors will be collected.
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis, Recurrent Disc Herniation
- Trial name
- EUROSPIN (NCT03398915)
- Testing
- Transpedicular Instrumentation
- Where
- 12 sites in Austria, France and 5 more
- Volunteers
- 932 people
- Sponsor
- Marc Schröder
the GERD Occurence
Thorcolumbar Kyphosis Patients With GERD
The investigator aimed to investigate the gastroesophageal reflux disease (GERD) along with esophageal motility in thoracolumbar kyphotic patients who meet surgical spinal correction criteria.
- Trial name
- NCT04521985
- Testing
- thoracolumbar kyphosis surgery
- Volunteers
- 30 people
- Sponsor
- National Taiwan University Hospital
Lumbar Disc Surgery
Comparing The Effect of Adding Dexmedetomidine to Bupivacaine in Classical and Modified Thoracolumbar Interfascial Plane Block on Postoperative Pain in Patients Undergoing Lumbar Disc Surgeries
Spinal surgeries are frequently conducted to stabilize the vertebrae and discs of the spine. These surgeries typically require substantial manipulation of subcutaneous tissues, bones, and ligaments .
- Trial name
- NCT06690021
- Testing
- Dexmedetomidine
- Volunteers
- 26 people
- Sponsor
- Assiut University
Healthy Individuals With Hamstring Tightness
The Immediate Effects Of Thoracolumbar Fascia Inhibition And Suboccipital Muscle Inhibition
This randomized controlled trial aimed to compare the immediate effects of two self-myofascial release techniques-suboccipital muscle inhibition and thoracolumbal fascia inhibition-on hamstring flexibility, spinal range of…
- Trial name
- NCT07096076
- Testing
- Thoracolumbar fascia inhibition, Suboccipital inhibition group, hamstring stretching
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Bulent Ecevit University
Thoracolumbar Disc Degeneration, Thoracolumbar Spondylolisthesis
The Degen Study: Post-market Clinical Follow-up on the PASS LP, PASS Degen and PASS Tulip Systems (PASS DEGEN)
The purpose of this post-market clinical study is to evaluate the long-term safety and efficacy of the MEDICREA's systems PASS LP, PASS DEGEN, and PASS Tulip PRIME to treat degenerative diseases.
- Conditions
- Thoracolumbar Disc Degeneration, Thoracolumbar Spondylolisthesis, Spinal Deformity, Spinal Degeneration
- Trial name
- PASS DEGEN (NCT04670536)
- Testing
- PASS LP implants, PASS DEGEN, PASS TULIP PRIME
- Where
- 4 sites in France
- Volunteers
- 77 people
- Sponsor
- Medicrea International
Surgery
Enhancing Thoracolumbar Burst Fracture Treatment
The optimal treatment for neurologically intact thoracolumbar fractures remains controversial. Percutaneous pedicle screw fixation (PPSF) has been proposed for these fractures; however, achieving satisfactory reduction can be…
- Trial name
- NCT06561997
- Testing
- Robot-assisted, Free-hand
- Where
- China
- Volunteers
- 182 people
- Sponsor
- Peng Liu
Spinal Disorders, Degenerative Spine Disease
Dose-Dependent Effects of Intraoperative Tranexamic Acid on Surgical Bleeding and Transfusion Requirements in Multilevel Thoracolumbar Spinal Surgery
Multilevel spinal stabilization surgery is frequently associated with substantial blood loss and increased transfusion requirements.
- Conditions
- Spinal Disorders, Degenerative Spine Disease, Blood Loss, Surgical
- Trial name
- NCT07288697
- Testing
- low-dose TXA, high-dose TXA
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Spinal Tumor
A Prospective Study of the Safety and Efficacy of 3D-printed Non-rigid Biomimetic Implant in Cervical and Thoracolumbar Spine
Vertebral body resection is a wide accepted procedure in tumor resection, deformity correction, and anterior decompression in spondylosis, ossification of posterior longitudinal ligaments, and spondylodiscitis surgery.
- Trial name
- NCT05396222
- Testing
- 3D-printed custom-made non-rigid biomimetic implant
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Taiwan University Hospital
Low Back Pain
Dry Needling at the Thoracolumbar Junction on Measures of Sympathetic Outflow and Flexibility
Dry needling (DN) is becoming more frequently performed by physical therapists around the world to treat musculoskeletal pain. Dry needling is a form of trigger point therapy that evolved from using injections of local…
- Trial name
- NCT03630172
- Testing
- Dry needling
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Nova Southeastern University
Fascia
Exercises Directed To Dynamic Stiffness Of The Thoracolumbar Region And Performance Of Amateur Runners
Introduction: Worldwide, the number of amateurs runners is growing exponentially, with consequent increase in musculoskeletal injuries.
- Trial name
- NCT05760664
- Testing
- Group Experimental/Fascial Fitness
- Where
- Brazil
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- University of the State of Santa Catarina
Lumbar Disc Herniation
Erector Spinae Plane Block and Modified-Thoracolumbar Interfascial Plane Block Following Lumbar Spinal Surgery
Ultrasound (US)-guided peripheral nerve blocks have been used increasily due to the advantages of ultrasound in anesthesia practice. TLIP block is one of these nerve blocks performed under US guidance.
- Trial name
- NCT04073095
- Testing
- Erector spinae plane block (Group E), modified-thoracolumbar interfascial plane block (Group T)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Medipol University
Intraoperative Complications, Intraoperative Bleeding
Ostene in Thoracolumbar Decompression and Fusion Evaluated With VIBE
In spine surgery, it is important to try to minimize bleeding. In particular, spine surgery often involves inserting hardware into bone, and/or removing bone in the spine.
- Conditions
- Intraoperative Complications, Intraoperative Bleeding, Intraoperative Blood Loss, Hemostasis
- Trial name
- Ostene VIBe (NCT06450834)
- Testing
- Ostene
- Where
- United States
- Volunteers
- 173 people
- Sponsor
- University of Maryland, Baltimore