Clinical trials: Thoracolumbar
Syndrome, Manganese Neurotoxicity
Effects of Thoracolumbar Stabilization Versus Spinal Decompression Exercises on Maigne's Syndrome
The study was conducted to compare the effect of thoracolumbar stabilization exercises versus spinal decompression exercises on pain, range of motion, disability and posture in patients with maigne's syndrome.
- Trial name
- NCT07426900
- Testing
- Lumbothoracic stabilization exercises, Spinal decompression exercises, Standardized physical therapy treatment
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- Riphah International University
Pain, Postoperative
Does a ThoracoLumbar Interfacial Plane (TLIP) Block With Liposomal Bupivacaine Provide TLIP Block in Spinal Surgery
The investigators are looking to recruit patients into a study demonstrating the effectiveness of a superficial nerve block involving the thoracolumbar interfascial plane (TLIP) in reducing postoperative pain in those undergoing…
- Trial name
- NCT04865211
- Testing
- Liposomal bupivacaine, Bupivacaine Injection
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Cooper Health System
Pedicle Screws, Surgery, Computer-Assisted/Adverse Effects
Pedicle Screws Placement Accuracy in Thoracolumbar Spine Using O-arm Navigation VS Standard Cervical Distractor Screws
Pedicle screw instrumentation is used nowadays mostly in spine fusion which is a surgical option for treating variety of conditions such as vertebral fractures, degenerative spine diseases, spine tumors and spine deformities.
- Conditions
- Pedicle Screws, Surgery, Computer-Assisted/Adverse Effects, Bone Screws, Imaging, Three-Dimensional/Methods
- Trial name
- NCT04196153
- Testing
- Pedicle screws instrumentation
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Abdullah International Medical Research Center
Fused Vertebrae, Ankylosing Spondylitis
Clinical Investigation of MONTAGE in Adults With Spinal Deformity Undergoing Pedicle Subtraction Osteotomy
This study evaluates the difference in postoperative bleeding between two study groups, FDA cleared MONTAGE Settable Resorbable Hemostatic Bone Putty and standard of care (no bone hemostat) during pedicle subtraction osteotomy…
- Conditions
- Fused Vertebrae, Ankylosing Spondylitis, Sagittal Deformities, Thoracolumbar Kyphosis
- Trial name
- NCT04125147
- Testing
- Experimental: Montage Bone Hemostat
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Abyrx, Inc.
Abdominal Muscle, Posture
The Effect Thoracolumbar Fascia on the Abdominal Muscle
The aim of this study was to evaluate the changes in the thickness of abdominal muscles during activation of thoracolumbar fascia through contracting the gluteus maximus and latissimus dorsi muscles.
- Conditions
- Abdominal Muscle, Posture, Muscle Strength
- Trial name
- NCT04113642
- Testing
- ultrasonographic measurement of abdominal muscle thickness at four positions
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Koç University
Thoracolumbar Burst Fractures
Vertebral Augmentation and Percutaneous Fixation for Thoracolumbar Burst Fractures Requiring Corpectomy
This study evaluates minimally invasive vertebral augmentation combined with percutaneous fixation for the treatment of severe thoracolumbar burst fractures.
- Trial name
- EXVERCOR (NCT07645092)
- Volunteers
- 30 people
- Sponsor
- University Hospital, Grenoble
Thoracolumbar Burst Fractures Without Neurologic Deficit
Brace Versus No Brace for the Treatment of Thoracolumbar Burst Fractures Without Neurologic Injury
Braces have been used o treat stable (not requiring surgery) burst fractures with much success. Recently questions have been raised in regards to the importance of the brace.
- Trial name
- NCT01741168
- Testing
- TLSO, No Orthosis
- Where
- Canada
- Volunteers
- 97 people
- Sponsor
- The London Spine Centre
Lumbar Vertebral Fracture
Percutaneous Screw Fixation vs. Open Fixation in the Treatment of Thoracolumbar Fractures
In this single-center retrospective study, the investigators will include all patients admitted to Parkland Hospital who underwent surgical fixation of thoracolumbar fractures between the years 2000 and 2017.
- Trial name
- PrecScrew (NCT04495400)
- Testing
- Thoracolumbar Fracture Fixation
- Where
- United States
- Volunteers
- 485 people
- Sponsor
- University of Texas Southwestern Medical Center
Thoracolumbar Compression Fractures
Short Segment Versus Long Segment Transpedicular Screw Fixation in the Correction and Preservation of AO-Type B Thoracolumbar Fracture Alignment: A Comparative Study
To compare the radiological, clinical and functional outcomes of short-segment versus long-segment transpediclular screw fixation in patients with thoracolumbar fractures AO-type B.
- Trial name
- NCT07777653
- Testing
- Short Segment Versus Long Segment Transpedicular Screw Fixation in the Correction and Preservation of AO-Type B Thoracolumbar Fracture Alignment: A Comparative Study
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Spine Surgery
Comprehensive Spinal Alignment Planning Study
A comprehensive approach to the evaluation of alignment in spinal surgery patients - through preoperative planning, intraoperative assessment, and postoperative confirmation - has not been well-studied.
- Trial name
- NCT02606695
- Testing
- NuvaMap O.R., NuvaMap
- Where
- 15 sites in United States
- Volunteers
- 306 people
- Sponsor
- NuVasive
Open Posterior Thoracolumbar Spinal Fusion Procedure
Single Versus Multi-Dose Oral and Intravenous Tranexamic Acid Patients at High Risk for Blood Transfusion After Spine Surgery
As tranexamic acid (TXA) becomes more prevalent, all patients are receiving the same dose and method of delivery regardless of their pre-operative risk of transfusion.
- Trial name
- NCT03849443
- Testing
- Tranexamic Acid Injectable Product (1000 mg intravenous bolus), Vitamin C 250 MG Oral Tablet, Tranexamic Acid 650Mg Tablet
- Where
- United States
- Volunteers
- 604 people
- Sponsor
- Rush University Medical Center
Chronic Low-back Pain, Myofascial Pain
Ultrasound Imaging for Myofascial Pain
The goal of this observational study is to develop and validate a biomarker for lumbar myofascial pain (MP) based on ultrasound obtained measurements of the lumbar muscles and fascia.
- Trial name
- NCT05928884
- Testing
- There is no intervention. It is a phenotyping study only
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Thoracolumbar Burst Fracture
Thoracolumbar Burst Fractures Study Comparing Surgical Versus Non-surgical Treatment
Thoracolumbar (TL) burst fractures in neurologically intact patients account for approximately 45% of all TL spine injuries. Despite being common fractures, there is significant variability in treatment recommendations…
- Trial name
- NCT02827214
- Where
- 14 sites in United States, Australia and 8 more
- Volunteers
- 213 people
- Sponsor
- AO Innovation Translation Center
Burst Fracture
Thoracolumbar Burst Fracture Treated With Pedicle Screws: Radiographic Outcomes
The surgical results of thoracolumbar and lumbar burst fracture have been reported to be comparable between patients with and without fusion in a midterm follow-up.
- Trial name
- NCT01979198
- Where
- Taiwan
- Volunteers
- 48 people
- Sponsor
- Taipei Veterans General Hospital, Taiwan
Healthy
Effect of Osteopathic Manual Techniques on the Diaphragm Muscle and Its Repercussions
Determining the effects of an intervention plan on the diaphragm related to the center of gravity and range of motion in the lumbar spine (static and dynamic) in healthy individuals is an area that lacks evidence and proper…
- Trial name
- NCT04399993
- Testing
- Intervention Protocol in Diaphragm
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Escola Superior de Tecnologia da Saúde do Porto
Thoracolumbar Spine
Screening for Kyphosis in the Mean Term in Patients Treated With Kyphoplasty Alone in the Management of Stable Traumatic Compression Fractures of the Thoracolumbar Spine
The aim of this retrospective study is to show that kyphoplasty is a reliable technique in the treatment of certain traumatic vertebral fractures.
- Trial name
- KIPHO (NCT02085811)
- Testing
- radiography standard
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Lumbar Fracture, Thoracic Fracture
Percutaneous Injection Plus Short Segment Pedicle Screw Fixation for Traumatic A2 and A3 AO-type Fractures in Adults
The aim of this study was to examine the short- to medium-term efficacy of percutaneous vertebral body reconstruction by vertebral body augmentation with Sr-HA paste plus short-segment pedicle screw fixation in fresh fractures…
- Trial name
- NEOGEL (NCT03431519)
- Testing
- VP
- Volunteers
- 38 people
- Sponsor
- University Hospital of Patras
Osteoporotic Fracture of Vertebra
Percutaneous Vertebral-disc Plasty for Thoracolumbar Very Severe Osteoporotic Vertebral Compression Fractures
Purpose: To compare the clinical outcomes and radiological parameters of patients undergoing percutaneous vertebroplasty (PVP) versus those undergoing percutaneous vertebral-disc plasty (PVDP) for back pain, segmental…
- Trial name
- NCT05519332
- Testing
- percutaneous vertebral-disc plasty
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Jiawei Jiang
Surgical Site Infection
Incisional Negative Pressure Wound Therapy in Patients Undergoing Spine Surgery
Introduction: Posterior post-operative spine wounds involving surgery at multiple levels are known to have higher rates of wound complications relative to other areas of the body.
- Trial name
- NCT03820219
- Testing
- Prevena™ system, Standard sterile wound dressing
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Nova Scotia Health Authority
Spine Fracture, Orthosis
ORthosis vs No Orthosis After Surgically Treated Traumatic Thoracolumbar Fractures
Rationale: There is no evidence in the current literature regarding the additional value of an orthosis after surgically treated thoracolumbar spine fractures.
- Conditions
- Spine Fracture, Orthosis, Traumatic Fracture, Posterior Fixation
- Trial name
- ORNOT (NCT03097081)
- Testing
- No orthosis, Orthosis
- Where
- Netherlands
- Volunteers
- 45 people
- Sponsor
- Amsterdam UMC, location VUmc