Clinical trials: Thoracoscopic Lobectomy
Lung Neoplasm, Physiology
Significance of Early Mobilization After VATS-L
The main endpoint is physiological rehabilitation after VATS-L under early mobilization. The secondary endpoints are exploring the effect of early mobilization on postoperative physiology.
- Conditions
- Lung Neoplasm, Physiology, Exercise, Lung Function
- Trial name
- NCT04508270
- Testing
- Early mobilization
- Where
- Denmark
- Volunteers
- 24 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Lobectomy
Tegileridine Combined With Intercostal Nerve Block After Thoracoscopic Lung Resection
Combining tegileridine PCIA with ICNB targeting peripheral nerves, may constitute an ideal analgesic model with complementary advantages.
- Trial name
- NCT07386626
- Testing
- Tegileridine, Intercostal Nerve Block, Sufentanil
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Tongji Hospital
Lung Cancer, Surgery--Complications
Assessment of the 90-day Mortality Risk Score After VATS Lobectomy
A five classes (A-E) aggregate risk score predicting 90-day mortality after video-assisted thoracoscopic lobectomy for lung cancer, including as independent factors male sex (3 points), carbon monoxide lung diffusion capacity…
- Conditions
- Lung Cancer, Surgery--Complications, Morality
- Trial name
- NCT04799509
- Testing
- VATS lobectomy
- Volunteers
- 2,209 people
- Sponsor
- Università degli Studi dell'Insubria
Lung Cancer
Disposable Powered Articulating Linear Cutter Stapler in Total-Thoracoscopic Anatomic Lobectomy (Segmentectomy)
To evaluate whether the anastomosis success rate of the main effectiveness evaluation indexes is not inferior to the similar products produced by Johnson \& Johnson when the Fengh Disposable Powered Articulating Endoscopic Linear…
- Trial name
- NCT05329402
- Testing
- Disposable Powered Articulating Endoscopic Linear Cutter Stapler, ECHELON Flex Powered Articulating Endoscopic Linear Cutters
- Where
- China
- Volunteers
- 164 people
- Sponsor
- Fengh Medical Co., Ltd.
Lung Cancer (Suspected or Confirmed), Thoracoscopic Lobectomy
Right Ventricular Afterload Indices in Lung Surgery
Lung cancer is a leading cause of cancer death in Scotland and the UK. Surgery, typically using a keyhole approach, provides the best chance of cure.
- Conditions
- Lung Cancer (Suspected or Confirmed), Thoracoscopic Lobectomy, One Lung Ventillation (OLV)
- Trial name
- RAILS (NCT07812207)
- Testing
- Contrast cardiac magnetic resonance imaging, Right heart catheterisation, Perioperative plasma sampling
- Volunteers
- 15 people
- Sponsor
- University of Glasgow
Thoracic, Surgery
Opioid-free Anesthesia in Thoracic Surgery
No study has been conducted to demonstrate the feasibility and safety of an Opioid-Free Anesthesia (OFA) protocol compared to Opioid-Based Anesthesia (OBA) in thoracic surgery, at risk for intense post-operative pain, to improve…
- Trial name
- VATOFA (NCT04246099)
- Testing
- Post-operative care
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Hospices Civils de Lyon
Cough
Effect of Bronchial Artery Protection on Cough After Thoracoscopic Lobectomy
The postoperative complications of thoracoscopic radical surgery for lung cancer mainly include postoperative bleeding, pulmonary infection, chylothorax, nerve injury, pulmonary embolism, arrhythmia, postoperative cough…
- Trial name
- NCT04651686
- Testing
- Preoperative three-dimensional reconstruction and intraoperative protection of bronchial artery
- Where
- China
- Volunteers
- 60 people
- Sponsor
- The First Affiliated Hospital of Soochow University
Methylprednisolone;Dihydroxypropyltheophylline;One Lung Ventilation;Respiratory Dynamics
Clinical Study of the Effect of Methylprednisolone Combined
Through the design of RCT study, the preoperative use of drugs (methylprednisolone + dihydroxypropyltheophylline) as intervention measures, the patients undergoing thoracoscopic lobectomy as the main research object, through the…
- Trial name
- NCT04810819
- Testing
- Methylprednisolone 40 MG Injection;Dihydroxypropyltheophylline;
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Qianfoshan Hospital
Atelectasis, Postoperative Pulmonary Complications
Effect of Inspired Oxygen Concentration on Postoperative Atelectasis After VATS Lobectomy
This study aims to investigate whether using 50% FiO₂ during one-lung ventilation, compared with 100% FiO₂, reduces postoperative atelectasis in the non-dependent (healthy) lung of patients undergoing VATS pulmonary lobectomy…
- Trial name
- NCT07721558
- Testing
- Low inspired oxygen concentration (FiO₂=50%) during one-lung ventilation, High inspired oxygen concentration (FiO₂=100%) during one-lung ventilaion
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking University People's Hospital
Postoperative Pain
Acute Pain Management Following Video-assisted Thoracoscopic Surgery: Comparison of Lobectomy and Wedge Resection
Viedo-assisted thoracoscopic surgery(VATS) have became popular in recent years. There is no golden rule of postoperative analgesia for VATS.
- Trial name
- NCT02130544
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Shared Mental Models, Video Assisted Thoracoscopic Surgery
Shared Mental Models and Technical Assessment in Video Assisted Thoracoscopy Surgery Lobectomies
To explore to what extent shared mental models (SMM) occur within the Video-Assisted Thoracoscopic Surgery (VATS) teams in a cardiothoracic surgery setting.
- Conditions
- Shared Mental Models, Video Assisted Thoracoscopic Surgery, Lobectomy, Technical Skills
- Trial name
- NCT02999113
- Where
- Denmark
- Volunteers
- 64 people
- Sponsor
- Copenhagen Academy for Medical Education and Simulation
Post-operative Pain
Ultrasound Guided Erector Spinae Plane Block in Patients Undergoing VATS Lobectomy
This study will compare ESP block plus patient-controlled analgesia (PCA) to intercostal nerve block plus PCA as post-operative pain control for patients having video-assisted thorascopic surgeries.
- Trial name
- NCT03176667
- Testing
- Ultrasound guided erector spinae plane block, Intercostal block
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- McMaster University
Video Assisted Thoracoscopic Surgery, Lobectomy
SERRATHOR TRIAL : Interest of the Novel Serratus Plane Block in Post Operative Analgesia After Video-Assisted Thoracoscopic Lobectomy
Pain after thoracic surgery remains a challenge for anesthetists. Although VATS for lobectomy is associated with fewer complications compared to thoracotomy, pain after VATS needs to be treated with opioids.
- Conditions
- Video Assisted Thoracoscopic Surgery, Lobectomy, Pain Post Operative, Regional Anesthesia
- Trial name
- SERRATHOR (NCT03867695)
- Testing
- Ropivacaine, sterile saline
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Strasbourg, France
Lung Cancer, Complication of Surgical Procedure
Comparison of LigaSure to Conventional Electrocoagulation in Video-assisted Thoracoscopic Surgery Lobectomy
Surgical treatment of lung cancer consists of two elements: anatomical lung resection (segmentectomy, lobectomy or pneumonectomy) followed by mediastinal lymph node dissection (MLND).
- Trial name
- NCT03125798
- Testing
- LigaSure™, Monopolar electrocautery
- Where
- Poland
- Volunteers
- 216 people
- Sponsor
- Wielkopolskie Centrum Pulmonologii i Torakochirurgii
Thoracic Paravertebral Block, Anesthesia Induction
The Impact of Ultrasound-Guided Superficial and Deep Paravertebral Nerve Blocks at the Superior Costotransverse Ligament on Hemodynamics During the Induction Phase of Thoracoscopic Lung Lobectomy: A Multicenter, Double-Blind, Randomized Controlled Trial
This study aims to determine whether performing a paravertebral nerve block at the superficial surface of the superior costotransverse ligament (SCTL) (without needle penetration of the SCTL) is more effective in maintaining…
- Conditions
- Thoracic Paravertebral Block, Anesthesia Induction, Hypotension on Induction
- Trial name
- NCT06841822
- Testing
- SCTL superficial plane block, SCTL deep plane block group
- Where
- China
- Volunteers
- 168 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Perioperative, Recovery
Comparing the Impact of Multimodal Prehabilitation to Aerobic Training on Patients Undergoing Thoracoscopic Lobectomy
In recent years, many studies have shown that prehabilitation based on aerobic training strategies could have a positive effect on the recovery of postoperative functional capacity in patients undergoing lung cancer surgery.
- Conditions
- Perioperative, Recovery, Prehabilitation, Thoracoschisis
- Trial name
- NCT04049942
- Testing
- Multimodal prehabilitation group, Aerobic training group
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Peking Union Medical College Hospital
Postoperative Pain
0.15 mg Spinal Morphine vs. no Treatment for Morphine Requirement After VATs.
Postoperative pain after Video-assisted Thoracoscopic Surgery (VAT) is still debating. Therefore the investigators conduct a study comparing 0.15 mg spinal morphine and control group in term of analgesia.
- Trial name
- NCT01979354
- Testing
- Spinal morphine
- Where
- Thailand
- Volunteers
- 40 people
- Sponsor
- Mahidol University
Lung Neoplasms
Uniportal Versus Triportal Thoracoscopic Lobectomy and Sublobectomy for Early Stage Lung Cancer
Lung cancer is one of the most common cancers in the world. At present, surgical resection is still the standard treatment for early stage lung cancer.
- Trial name
- NCT02933294
- Testing
- Triportal pulmonary resection surgery, Uniportal pulmonary resection surgery
- Where
- 4 sites in China
- Volunteers
- 356 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Lung Surgery, Enhanced Recovery After Surgery, ERAS
Evaluation of the Effectiveness of Enhanced Recovery After Surgery (ERAS) Program in Pediatric Lung Surgery
This study aims to evaluate the clinical effectiveness of the Enhanced Recovery After Surgery (ERAS) program for pediatric lung surgery at our institution.
- Conditions
- Lung Surgery, Enhanced Recovery After Surgery, ERAS, Pediatric
- Trial name
- NCT07241286
- Testing
- Enhanced Recovery After Surgery, ERAS
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Non-Small Cell Lung Cancer
20-Fr Versus 24-Fr Chest Drains After Uniportal VATS Lobectomy for NSCLC
This randomized clinical trial compared two different chest drain sizes, 20 Fr and 24 Fr, in patients undergoing lung lobectomy for lung cancer.
- Trial name
- DRAIN2024 (NCT07827885)
- Testing
- 20-Fr Thoracic Drain, 24-Fr Thoracic Drain
- Where
- Italy
- Volunteers
- 80 people
- Sponsor
- Fondazione Policlinico Universitario Campus Bio-Medico