Clinical trials: Thoracotomy
Postoperative Pain
Morphine Consumption in Thoracotomy
Importance of effective postoperative pain management is well known. The undesired effects of pain can be prevented with multimodal analgesia for the patient. Thoracotomy operations are associated with high levels of pain.
- Trial name
- NCT04999319
- Testing
- PVB, ESPB
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Kocaeli University
Postoperative Pain
NSAIDs With Morphine-PCA Compared to Epidural Analgesia in Thoracotomy Pain
The investigators investigated whether a strictly controlled pain management with patients participating in a clinical study can attenuate persistence of post-thoracotomy pain.
- Trial name
- NCT01541137
- Testing
- Diclofenac, parecoxib/ valdecoxib, patient controlled epidural analgesia
- Where
- Finland
- Volunteers
- 30 people
- Sponsor
- Helsinki University Central Hospital
Postoperative Pain, Thoracotomy
Effect of Continue RISS Block in Thoracotomy
Thoracotomy is one of the most painful surgery. Acute postoperative pain increases postoperative morbidity and prolongs hospital stay and also may lead to developing a chronic pain syndrome.
- Trial name
- NCT04443556
- Testing
- Tramadol, IV PCA
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Konya Meram State Hospital
Pain
The cryoICE™ CryoAnalgesia Study For Pain Management in Post thoRacic Procedures Via intercOSTal Cryoanalgesia (FROST)
The investigators propose to assess whether intra-operative intercostal cryoanalgesia using the cryoICE® probe (AtriCure®, Inc., 7555 Innovation Way, Mason, Ohio) provides superior post-operative analgesic efficacy as compared to…
- Trial name
- FROST (NCT02922153)
- Testing
- Cryoanalgesia, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 84 people
- Sponsor
- AtriCure, Inc.
Lung Disease, Pulmonary Lobectomy
PleuraSeal Post Market Study (Europe)
To further characterize the PleuraSeal Sealant System as compared to standard of care (sutures and staples only) in subjects undergoing an elective pulmonary lobectomy and segmentectomy via open thoractomy.
- Trial name
- NCT00704171
- Testing
- Standard Tissue Closure Techniques, PleuraSeal Lung Sealant System
- Where
- 9 sites in United States, Austria and 4 more
- Volunteers
- 121 people
- Sponsor
- Integra LifeSciences Corporation
Cold Exposure
Simulation Study on Advanced Medical Procedures Under Extreme Environments
Background: In emergency situations in mountainous regions, medical professionals are often required to perform advanced medical procedures swiftly and efficiently.
- Trial name
- SIMEX-MED (NCT06640595)
- Where
- Italy
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Institute of Mountain Emergency Medicine
Calcitonin, Paravertebral
Paravertebral Calcitonin in Thoracotomy
This prospective randomized double-blinded controlled study will be conducted to evaluate the effect of adding calcitonin to bupivacaine in thoracic paravertebral block for patients undergoing thoracotomy.
- Conditions
- Calcitonin, Paravertebral, Thoracotomy
- Trial name
- NCT06330168
- Testing
- bupivacaine-calcitonin-fentanyl, Bupivacaine-fentanyl
- Where
- Egypt
- Volunteers
- 92 people
- Sponsor
- Tanta University
Shoulder Pain
Superficial Cervical Plexus Block for Shoulder Pain After Lung Surgery
The investigators want to know whether injecting numbing medication on the side of the neck (also called superficial cervical plexus block) can prevent or reduce shoulder pain that patients commonly experience after lung surgery.
- Trial name
- SCPB (NCT01550302)
- Testing
- Superficial Cervical Plexus Block, Bupivacaine
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Washington
Parapneumonic Effusion, Empyema, Pleural
Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication
This study aims to standardize the treatment of pleural space (parapneumonic) infections by comparing the difference in outcomes between 2 methods of treatment: early VATS (Video Assisted Thorascopic Surgery) decortication versus…
- Conditions
- Parapneumonic Effusion, Empyema, Pleural, Coagulopathy
- Trial name
- NCT03583931
- Testing
- VATS Decortication, Fibrinolytic Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Denver Health and Hospital Authority
Pain, Postoperative, Opioid Use
Exparel vs. Marcaine ESP Block for Post-cardiac Surgical Pain
The goal of this pilot study is to describe and compare Ultrasound-Guided Erector Spinae Plane (ESP) Blocks using Exparel® (bupivacaine liposome injectable suspension) to Marcaine® (bupivacaine hydrochloride) for pain management…
- Conditions
- Pain, Postoperative, Opioid Use, Perioperative Complication, Heart Diseases
- Trial name
- NCT06077422
- Testing
- bupivacaine liposome injectable suspension, Bupivacaine Hydrochloride
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Rutgers, The State University of New Jersey
Pulmonary Nodule
Effects of Surgery Types in Patients With Pulmonary Nodules
The investigators aimed to compare the pre-post operative effects of video-assisted thoracoscopy surgery (VATS) and thoracotomy on pulmonary function, exercise capacity, physical activity level, respiratory and peripheral muscle…
- Trial name
- NCT04805723
- Testing
- VATS, Thoracotomy
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Gazi University
Pain
Comparison of the Clinical Efficacy of 2 Paravertebral Block Strategies in Thoracic Surgery by Thoracotomy: by the Anesthetist (Paravertebral Block Guided by Ultrasound) and by the Thoracic Surgeon (Paravertebral Block Visual)
Post-thoracotomy pain is one of the most severe. The local analgesia allows its effective control and a reduction of postoperative morbidity and mortality. The gold standard for local analgesia is the thoracic epidural.
- Trial name
- PVBS-USguided (NCT02865226)
- Testing
- paravertebral block by the anesthetist before incision (paravertebral block guided by ultrasound), paravertebral block by the thoracic surgeon at chest closure (paravertebral block visual).
- Where
- France
- Volunteers
- 50 people
- Sponsor
- CHU de Reims
Lung Cancer
Study to See if Microcoil Insertion Reduces the Rate of Open Thoracotomy for Removal of Lung Nodules
LAY ABSTRACT 1. Statement of the health problem or issue: Of the estimated 24,000 Canadians who will be diagnosed with lung cancer in 2008, 21,000 will die of their disease.
- Trial name
- NCT01028417
- Testing
- Platinum microcoil
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- University of British Columbia
Pain
Postoperative Analgesic Effects of Using Dexmedetomidine for Ultrasound Guided Thoracic Paravertebral Block
we aimed postoperative analgesic effects of using bupivacaine alone or added dexmedetomidine for ultrasound guided thoracic paravertebral block in thoracotomy
- Trial name
- NCT02544893
- Testing
- bupivacaine, dexmedetomidin, serum physiologic
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- TC Erciyes University
Post Operative Pain
Post-Operative Kinesio Taping Impact on Pain in Thoracotomy vs Thoracoscopy
The project is of a comparative nature. It seeks to study pain reduction following two forms of chest surgery and compare results between both procedures. It will use kinesio taping as the studied pain reducer.
- Trial name
- NCT05200689
- Testing
- Kinesiotaping (KT)
- Where
- 5 sites in Egypt, Italy and 2 more
- Volunteers
- 310 people
- Sponsor
- Al-Quds University
Lung Cancer
Neuropathic in the Acute Post Operative Phase
Investigation of thermal thresholds and sensory mapping to thermal stimuli
- Trial name
- NCT01300702
- Where
- 2 sites in Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Post-thoracotomy Pain Syndrome
Effects of Intravenous Acetaminophen in Patients Undergoing Thoracoscopic Surgery
This is a single-center, randomized, double-blind, placebo-controlled trial. A total of 100 patients, 50 per treatment arm, undergoing minimally invasive thoracic surgery will be randomized 1:1 across 2 treatment arms: Ofiramev®…
- Trial name
- IVTylenol (NCT03051932)
- Testing
- Ofiramev® (IV Acetaminophen)
- Sponsor
- The University of Texas Medical Branch, Galveston
Laser Therapy, Post Thoracotomy Pain
Laser Therapy in the Treatment of Post Thoracotomy Pain; A Pilot Study
The purpose of this study is to demonstrate the safety of the AvicennaTM class IV laser for application over the skin of human subjects.
- Trial name
- NCT00623909
- Testing
- AvicennaTM class IV laser application
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Pulmonary Malformation
Can Pre-operative Flexible 3D Models of Pulmonary Malformations Facilitate Thoracoscopic Resection
The National Rare Diseases plans, the ongoing MALFPULM PHRC and thoracoscopic advents in children, are remarkable improvements in understanding and managing lung malformations.
- Trial name
- 3DLP (NCT03913416)
- Testing
- 3D printed model, Control group
- Where
- France
- Volunteers
- 178 people
- Sponsor
- Hospices Civils de Lyon
Pain, Acute, Breathing, Mouth
Combined Acupressure Effects on Post-Thoracotomy Pain and Lung Volume
Pain is a subjective, sensory and emotionally unpleasant experience resulting from real or hidden injuries in tissues. The pain experience is a subjective and unique experience in physiological and psychological terms and is the…
- Conditions
- Pain, Acute, Breathing, Mouth, Relaxation; Diaphragm, Cough
- Trial name
- NCT07411417
- Testing
- Acupressure group
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Özgül Aydemir