Clinical trials: Thoracotomy Analgesia
Thoracostomy Pain Management, Pain Management
The Clinical Impact of Serratus Anterior VS. Erector Spinae Plane Block on Pain Management of Tube Thoracostomy in Emergency Department Patients.
In the emergency department, tube thoracostomy is a common critical procedure to manage symptomatic pleural issues such as pneumothorax and pleural effusion.[1] This technique employed to remove air or fluid from the pleural…
- Conditions
- Thoracostomy Pain Management, Pain Management, Chest Tube Insertion
- Trial name
- NCT07823920
- Testing
- serratus anterior plane blocks, Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Postthoracotomy Pain
Comparison of Serratus Posterior Superior Intercostal Plane Block and Paravertebral Block for Post-Thoracotomy Pain Management
Patients undergoing thoracic surgery via thoracotomy are required to remain in the lateral decubitus position for prolonged periods due to surgical access requirements.
- Trial name
- NCT07768826
- Testing
- Serratus Posterior Superior Intercostal Plane Block (SPSIPB), Paravertebral Block (PVB)
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Ankara City Hospital Bilkent
Post Thoracotomy Pain
Continuous Paravertebral Block by Intraoperative Direct Access Versus Systemic Analgesia for Postthoracotomy Pain Relief
to evaluate the safety and efficacy of continuous paravertebral block by intraoperative direct access on postthoracotomy pain compared to systemic analgesia.
- Trial name
- NCT04482192
- Testing
- Thoracic paravertebral block, Systemic analgesia
- Volunteers
- 63 people
- Sponsor
- Zagazig University
Pain, Postoperative, Anesthesia
The Efficacy of Serratus Anterior Plane Block (ESAPB) for Thoracotomy: a Prospective Study
Thoracotomy is considered the most painful surgical procedure. Ultrasound-guided serratus anterior plane block (SAPB) is a relatively new truncal block method treating thoracotomy pain.
- Conditions
- Pain, Postoperative, Anesthesia, Thoracotomy
- Trial name
- NCT03839160
- Testing
- Serratus anterior plane block, Intravenous patient-controlled-analgesia morphine
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Zhongshan Hospital
Pain Following Thoracotomy Surgery
Study of Exparel Versus Epidural for Pain Control After Thoracotomy
Unilateral intercostal nerve blocks provide pain control as effectively as a continuous thoracic epidural, and will a lower incidence of side effects.
- Trial name
- NCT02178553
- Testing
- Epidural, Intercostal Bupivicaine (Exparel)
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Mayo Clinic
Pain
The cryoICE™ CryoAnalgesia Study For Pain Management in Post thoRacic Procedures Via intercOSTal Cryoanalgesia (FROST)
The investigators propose to assess whether intra-operative intercostal cryoanalgesia using the cryoICE® probe (AtriCure®, Inc., 7555 Innovation Way, Mason, Ohio) provides superior post-operative analgesic efficacy as compared to…
- Trial name
- FROST (NCT02922153)
- Testing
- Cryoanalgesia, Standard of Care
- Where
- 5 sites in United States
- Volunteers
- 84 people
- Sponsor
- AtriCure, Inc.
Erector Spinae Plane Block, Local Anesthetic
The Effect of Different Local Anesthetic Volumes on Postoperative Analgesia for Thoracotomy Patients With Erector Spinae Plane Block
It is widely accepted that thoracotomy causes severe acute pain. This increases the frequency of postoperative pulmonary complications and postoperative morbidity.
- Conditions
- Erector Spinae Plane Block, Local Anesthetic, Thoracotomy, Postoperative Analgesia
- Trial name
- NCT05083845
- Testing
- Same blocks with different local anesthetic volume
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Atatürk Chest Diseases and Chest Surgery Training and Research Hospital
Posterolateral Thoracotomy, Lung Resection
Effect of Thoracic Epidural Analgesia for Thoracotomy on the Occurrence of AF
Thoracic epidural anesthesia and analgesia for patients undergoing lung resection can reduce the occurrence of AF if it is continued for six postoperative days instead of just three.
- Conditions
- Posterolateral Thoracotomy, Lung Resection, Thoracic Epidural Analgesia, Sympathetic Outflow
- Trial name
- NCT01718717
- Testing
- Thoracic Epidural Analgesia (TEA), TEA followed by Intravenous morphine
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- Larissa University Hospital
Pain, Postoperative
Prospective, Randomised, Single-Blinded, Monocentric Clinical Study to Compare Postoperative Analgesia and Outcome After Combined Paravertebral and Intrathecal Versus Thoracic Epidural Analgesia for Thoracotomy
The purpose of this study is to compare whether epidural analgesia would provide equal analgesia than combining intrathecal opioids with thoracic paravertebral local anesthetics.
- Trial name
- NCT00493909
- Testing
- intrathecal opioids and thoracic paravertebral analgesia, thoracic epidural analgesia
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- University Hospital Freiburg
Nerve Block/Methods
Comparing Suprascapular Nerve Block and Interscalene Block for Post-thoracotomy Pain in Pediatric Patients.
The goal of this clinical trial is to determine which regional block provides superior analgesia in pediatric patients undergoing thoracic surgery.
- Trial name
- NCT07796399
- Testing
- Interscalene brachial plexus block, anterior Supraclavicular nerve block, Thoracic Epidural Analgesia (TEA) only
- Where
- Egypt
- Volunteers
- 126 people
- Sponsor
- Children's Cancer Hospital Egypt 57357
Postoperative Pain Management
Study in Adult Subjects Undergoing Posterolateral Thoracotomy
Primary Objective: To characterize the pharmacokinetic (PK) profile of EXPAREL when administered as a posterior intercostal nerve block. Secondary Objective: To assess the safety and tolerability of EXPAREL in this surgical model.
- Trial name
- NCT03428984
- Testing
- EXPAREL
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Postoperative Pain, Thoracic Surgery
Intravenous Lidocaine, Ketamine, and Magnesium in Thoracic Surgery
Thoracic surgery often produces severe postoperative pain due to nerve injury and inflammation. Effective pain control is essential to reduce complications and opioid use.
- Conditions
- Postoperative Pain, Thoracic Surgery, Multimodal Analgesia, Opioid Consumption, Postoperative
- Trial name
- LKM-Thorax (NCT07359469)
- Where
- Spain
- Volunteers
- 118 people
- Sponsor
- Universidad Pública de Navarra
Thoracotomy
Effect of Bupivacaine in Ultrasound-guided Erector Spinae Plane
To investigate the effect of two different volumes of bupivacaine 0.25% used in ultrasound-guided erector spinae plane (ESP) block on dermatome spread and postoperative analgesia in patients undergoing unilateral thoracotomy
- Trial name
- NCT03650335
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Yuzuncu Yil University
Thoracotomy, Thoracotomy Analgesia
Compare the Perioperative Analgesic Effect of Ultrasound Guided Thoracic Paravertebral Block and Ultrasound Guided Serratus Anterior Block in Patients Undergoing Thoracotomy
The aim of this study is to compare the perioperative analgesic effect of ultrasound guided thoracic paravertebral block and ultrasound guided serratus anterior block in patients undergoing thoracotomy.
- Trial name
- thoracotomy (NCT06831578)
- Testing
- seratuse anterior plane block, paravertebral plane block
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Menoufia University
Pain, Postoperative
Serratus Anterior Plane Block Versus Intercostal Block
Pain after thoracotomy is the most severe pain experienced by the patient. Good pain control after the operation provides comfortable respiration and reduces the development of chronic pain and complications.
- Trial name
- NCT03309267
- Testing
- Intercostal block, Serratus anterior plane block
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Chest Tube, Thoracotomy
Position to Prevent Pleural Irritation (PPPI) for Pain and Sleep
Clinical Trial Aim: The study was conducted to investigate the effect of the Position given to Prevent Pleural Irritation (PPPI) due to chest tube on pain level and sleep quality in patients undergoing thoracic surgery.
- Conditions
- Chest Tube, Thoracotomy, Pain, Sleep
- Trial name
- NCT06919978
- Testing
- The Position to Prevent Pleural Irritation (PPPI)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Akdeniz University
Pain, Thoracotomy
Continuous Wound Catheter Analgesia Associated With Intravenous Morphine PCA After Thoracotomy
Objective: Epidural analgesia is the gold standard for post-thoracotomy pain relief but is contraindicated in certain patients. An alternative is continuous wound catheter analgesia.
- Trial name
- NCT01698203
- Testing
- ropivacaine 0.75% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun), ropivacaine 0.2% - device : wound catheter Silver™ 19 cm and Easypump™ 400 mL (BBraun)
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Strasbourg, France
Postoperative Analgesia, Thoracic Surgery
Comparison of Erector Spina Plane Block and Thoracic Paravertebral Block for Analgesia After Thoracotomy
This study aims to compare the postoperative analgesic efficacy of ultrasound-guided erector spinae plane block (ESPB) and thoracic paravertebral block (TPVB) in patients undergoing thoracotomy.
- Trial name
- NCT06778161
- Testing
- nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Elzem SEN
Pain, Postoperative
The Effect of Gabapentin on Thoracic Epidural Analgesia Following Thoracotomy
The purpose of this trial is to investigate the effect of gabapentin on thoracic epidural analgesia following thoracotomy, including assessment of both analgesia, pain intensity, pain quality and whether or not gabapentin…
- Trial name
- GABATEA (NCT01116583)
- Testing
- Gabapentin
- Where
- Denmark
- Volunteers
- 104 people
- Sponsor
- University of Aarhus
Restlessness, Pain
Effects of Dexmedetomidine on Stress Response and Postoperative Analgesia
Dexmedetomidine is a highly selective α2 adrenoreceptor agonist approved by the US FDA for short-term postoperative sedation and analgesia.It can also reduce the stress response without respiratory depression.
- Trial name
- NCT01517932
- Testing
- dexmedetomidine
- Volunteers
- 60 people
- Sponsor
- Fang Luo