Clinical trials: Thoracotomy Surgery
Chronic Pain, Post-thoracotomy Pain Syndrome
Botulinum Toxin A as Treatment for Chronic Postsurgical Pain Following Lung Cancer Surgery
Chronic postsurgical pain following lung cancer surgery is common with and 20-60 % develop chronic pain which persists more than six months after surgery. Causes and health impact of this pain have been comprehensively studied.
- Conditions
- Chronic Pain, Post-thoracotomy Pain Syndrome, Pain, Neuropathic, Pain, Postoperative
- Trial name
- NCT04585620
- Testing
- Onabotulinum Toxin A, Normal saline
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Allan Vestergaard Danielsen, MD
Cardiac Surgery Subjects
Objective Measurement of the Mechanical Pain Threshold With an Algometer for Predicting Intraoperative Opioid Consumption in Patients Who Will be Operate by Thoracotomy and Sternotomy in Cardiac Surgery
The study aims to test the relationship between the preoperative pain threshold and the intraoperative need for opioids. The objective of the study is to try to predict a patient's analgesic needs based on their objectively…
- Trial name
- NCT07513974
- Testing
- Measure of the minimal pain threshold with an algometer
- Where
- Belgium
- Volunteers
- 100 people
- Sponsor
- Université Libre de Bruxelles
Chest Tube, Thoracotomy
Position to Prevent Pleural Irritation (PPPI) for Pain and Sleep
Clinical Trial Aim: The study was conducted to investigate the effect of the Position given to Prevent Pleural Irritation (PPPI) due to chest tube on pain level and sleep quality in patients undergoing thoracic surgery.
- Conditions
- Chest Tube, Thoracotomy, Pain, Sleep
- Trial name
- NCT06919978
- Testing
- The Position to Prevent Pleural Irritation (PPPI)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Akdeniz University
Pneumothorax
Video-assisted Thoracic Surgery (VATS) Versus Axillary Mini-thoracotomy for the Treatment of Recurrent Spontaneous Pneumothorax
The investigators conducted a prospective randomized study to compare axillary minithoracotomy versus a modified two-port thoracoscopic technique for surgical pleurodesis in patients with recurrent spontaneous pneumothorax…
- Trial name
- NCT01192217
- Testing
- Modified thoracoscopic technique, Axillary mini-thoracotomy
- Where
- Greece
- Volunteers
- 66 people
- Sponsor
- AHEPA University Hospital
Postoperative Pain, Cancer
Analgesic Efficacy of Inter Pleural Ropivacaine Road in Post Thoracotomy Pain for Oncologic Surgery
Thoracic surgery via posterolateral thoracotomy causes significant postoperative pain. There are several methods of postoperative pain relief, including intravenous analgesics and local-regional analgesia techniques.
- Trial name
- ROPAL-1 (NCT00210132)
- Testing
- Ropivacaine, Reference
- Where
- France
- Volunteers
- 90 people
- Sponsor
- Institut Bergonié
Neuropathic Pain, Thoracic Surgery, Video Assisted
Chronic Pain After Thoracotomy (Video Assisted Thoracic Surgery - VATS)
This is an explorative study investigating potential nerve injury after VATS.
- Conditions
- Neuropathic Pain, Thoracic Surgery, Video Assisted, Chronic Pain
- Trial name
- NCT01068457
- Where
- Denmark
- Volunteers
- 48 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Video Assisted Thoracoscopic Surgery, Thoracic Surgery
Diaphragmatic Thickness and Functional Exercise Capacity in Lobectomy Surgeries With Thoracotomy and VATS
The most commonly treatment for early stage non-small cell lung cancer (NSCLC) is lobectomy. Different surgical interventions during lobectomy are thought to have different effects on respiratory functions and exercise…
- Conditions
- Video Assisted Thoracoscopic Surgery, Thoracic Surgery, Respiratory Muscles
- Trial name
- NCT05669196
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Hacettepe University
Lung Cancer
Evaluation of Chronic Pain After Nerve Section During Thoracotomy
The purpose of this study is to investigate if controlled nerve section reduces chronic pain after thoracotomy.
- Trial name
- NCT00653367
- Testing
- Nerve section
- Where
- Denmark
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Heart Surgery
Study of Diaphragm Mobility on Tissue Doppler
Diaphragm dysfunction is found in 10 to 90% of patients following heart surgery. In current practice diaphragm dysfunction is evaluated by 2D ultrasonography. Tissue Doppler is a validated technique to study heart contractility.
- Trial name
- DD (NCT03295344)
- Testing
- Diaphragm ultrasonography, Tissue Doppler
- Where
- France
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire Dijon
Video-assisted Thoracoscopic Surgery
Low-dose Spinal Morphine for Post-Thoracotomy Pain After Video-Assisted Thoracoscopic Surgery
One-thirds of patients underwent video-assisted thorascopic surgery still have severe pain. Therefore we want to demonstrate weather 0.15 mg spinal morphine would reduce 24 hour postoperative requirement comparing to control…
- Trial name
- NCT01917448
- Testing
- Morphine, control
- Where
- Thailand
- Volunteers
- 36 people
- Sponsor
- Mahidol University
Acute Postoperative Pain, Thoracotomy Surgery
Intertransverse Process Block for Postoperative Analgesia After Thoracotomy and Lobectomy
This prospective, randomized, triple-blind, placebo-controlled clinical trial will investigate the effectiveness of the intertransverse process block (ITPB) for postoperative analgesia in patients undergoing elective thoracotomy…
- Conditions
- Acute Postoperative Pain, Thoracotomy Surgery, Intertransverse Process Block
- Trial name
- NCT07335250
- Testing
- Intertransverse Process Block
- Where
- Turkey (Türkiye)
- Volunteers
- 66 people
- Sponsor
- Konya City Hospital
Carcinoma, Non-Small-Cell Lung
ELobectomy for NSCLC by VATS Versus Thoracotomy (ECTOP-1007)
This study is one of Eastern Cooperative Thoracic Oncology Projects (ECTOP-1007). The goal of this study is to determine video-assisted thoracoscopic surgery is non-inferior to thoracotomy in terms of disease-free survival for…
- Trial name
- NCT03786003
- Testing
- VATS, Thoracotomy
- Where
- China
- Volunteers
- 1,086 people, healthy volunteers welcome
- Sponsor
- Fudan University
Postoperative Analgesia, Thoracic Surgery
Comparison of Erector Spina Plane Block and Thoracic Paravertebral Block for Analgesia After Thoracotomy
This study aims to compare the postoperative analgesic efficacy of ultrasound-guided erector spinae plane block (ESPB) and thoracic paravertebral block (TPVB) in patients undergoing thoracotomy.
- Trial name
- NCT06778161
- Testing
- nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 130 people
- Sponsor
- Elzem SEN
Minimal Invasive Cardiac Surgery, Limited Right Anterior Thoracotomy for Mitral Valve Replacement
Efficacy of Limited Right Anterior Thoracotomy Versus Median Sternotomy for Mitral Valve Replacement
this study compare between two diffrent methods for approach mitral valve in mitral valve replacement throgh opening of the middle of the sternum by saw or through opening between 4th and 5th rib on the right side of the chest…
- Trial name
- NCT06869980
- Testing
- mitral valve replacement through limited right anterior thoractomy, mitral valve replacement through median sterntomy
- Where
- Egypt
- Volunteers
- 41 people
- Sponsor
- Zagazig University
Erector Spina Plan Block, Preemptive Analgesia
Comparison of the Effect of Preemptive and Post-operative Erector Spina Plane Block on Intraoperative Opioid Consumption and Postoperative Analgesia in Patients Who Will Undergo Elective Thoracotomy Surgery, Guided by the Nociception Level Index (NoL)
The patients who will participate in the study will be determined and informed according to the inclusion and exclusion criteria, and the patients who signed the informed consent form will be included in the study.52 patients who…
- Conditions
- Erector Spina Plan Block, Preemptive Analgesia, Thoracotomy, Nociception Level Index(NoL)
- Trial name
- NCT05944523
- Testing
- Erector Spina Plan Block
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Ankara University
Laparotomy, Thoracotomy
Peritoneal Cavity Conditioning During Open Surgery.
Given the observations in animal models and the available data in the human our hypothesis is that peritoneal cavity conditioning (carbon dioxide with 4% of oxygen and 10% of N2O, 100% humidification at 32°C,) during open…
- Trial name
- NCT01098175
- Where
- Belgium
- Volunteers
- 40 people
- Sponsor
- KU Leuven
Thoracic Surgery
Pressure-Controlled vs Volume-Controlled Ventilation During One Lung Ventilation
Compared with the information available in sepsis and trauma-associated ARDS, less is known about the cause and pattern of lung injury after thoracic surgery. Definition of lung injury in this context is difficult.
- Trial name
- NCT00975468
- Testing
- Pressure Controlled vs. Volume Controlled Ventilation during OLV
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- King Faisal University
Elective Open Thoracotomy
Remifentanil Without Muscle Relaxant for Thoracotomy
Although the administration of muscle relaxation is essential standard of care for thoracic procedures, it could cause long-reversal times and postoperative residual curarization (PORC) increasing length of post-anesthesia care…
- Trial name
- NCT02030808
- Testing
- Muscle Relaxants (MR) group, Non- Muscle Relaxants (NMR) group
- Where
- Saudi Arabia
- Volunteers
- 66 people
- Sponsor
- Imam Abdulrahman Bin Faisal University
Lung Cancer, Robotic Thoracic Surgery
Impact of Robotic Approach Compared to VATS and Open Approach on Quality of Life in Patients With Lung Cancer
The aim of the study is to compare quality of life and early and late post-operative pain after anatomical lung resection (lobectomy or segmentectomy) performed by a robotic approach compared to the videothoracoscopic approach…
- Conditions
- Lung Cancer, Robotic Thoracic Surgery, Video-assisted Thoracis Surgery (VATS), Open Thoracotomy Surgery
- Trial name
- QoL (NCT04353349)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Clinico Humanitas
Lung Cancer
Sensory Mapping and Thermal Thresholds After Thoracic Surgery
The study will investigate topography of sensory changes late after lung cancer surgery
- Trial name
- NCT01274858
- Where
- 2 sites in Denmark
- Volunteers
- 12 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet