Clinical trials: Threatened Preterm Labor
Preterm Delivery Within 7 Day After Admission
Management of Threatened Preterm Labor by Cervical Length-based Approach or Conventional Approach
To compare the effectiveness of treatment of threatened preterm labor between transvaginal cervical length-based approach and conventional approach (Per vaginal examination)
- Trial name
- NCT04301388
- Testing
- Transvaginal ultrasound
- Where
- 2 sites in Thailand
- Volunteers
- healthy volunteers welcome
- Sponsor
- Chiang Mai University
Preterm Birth
Fetal Adrenal Gland Volume Estimation in Prediction of Preterm Birth
If we could prove that three -dimensional ultrasound measurement of fetal adrenal gland volume can accurately predict the likelihood of preterm birth in patients having symptoms and signs of PTL , we would be able to use it as a…
- Trial name
- NCT02339623
- Testing
- Ultrasound imaging
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Ain Shams Maternity Hospital
Obstetric Labor, Premature
Impact of Threatened Preterm Labour in Fetal Cardiovascular and Metabolic Programming (SHs)
The goal of this observational study is to learn about cardiac function and remodelling and metabolomic profiles in fetuses and infants who were exposed to a threatened preterm labor (TPL) during pregnancy.
- Trial name
- SHs (NCT05670665)
- Testing
- Threatened preterm labor
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Preterm Birth, Hyperglycemia
Blood Glucose in Pregnant Non-diabetic Women During Treatment With Betamethasone for Fetal Lung Maturation
In case of threatening preterm birth, it is standard to recommend treatment with betamethasone to accelerate fetal lung maturation.
- Conditions
- Preterm Birth, Hyperglycemia, Neonatal Hypoglycemia, Threatened Preterm Labor
- Trial name
- NCT06794307
- Where
- Denmark
- Volunteers
- 25 people
- Sponsor
- University of Aarhus
Preterm Delivery.
Utility of Tocolytic Therapy for Maintenance Tocolysis in the Management of Threatened Preterm Delivery
Hypothesis: Both nifedipine or progesterone are widely used in clinical practice as maintenance tocolytic therapy after an episode of threatened preterm delivery.
- Trial name
- UTM/2012 (NCT01796522)
- Testing
- progesterone 200 mg / day vaginally, nifedipine (60 mg / day orally)
- Where
- Spain
- Sponsor
- Instituto de Investigacion Sanitaria La Fe
Preterm Birth
Prevention of Preterm Birth in Singletons Using Pessary After Resolutive Threatened Preterm Labor
In France, threatened preterm labour concerns 6.5% of pregnancies and is associated with a premature birth in 25.4% of cases. After 48 hours effective tocolysis, patients do not receive any further treatment while their risk of…
- Trial name
- PREMAPESSAIRE (NCT02484820)
- Testing
- Silicone pessary
- Where
- France
- Volunteers
- 168 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Preterm Birth, Obstetric Labor, Premature
Prevention of Preterm Labor in Patients With a Previous Episode of Threatened Preterm Labor With Progesterone
The purpose of this study is to determine if the use of 250 mg of intramuscular progesterone biweekly can reduce the incidence of preterm labor in patients with an episode of threatened preterm labor during the current pregnancy.
- Trial name
- NCT01317225
- Testing
- 17 α hydroxyprogesterone caproate
- Where
- Panama
- Volunteers
- 80 people
- Sponsor
- Saint Thomas Hospital, Panama
Preterm Labour
Fetal Adrenal Gland Volume Estimation Compared to Cervical Length Assessment in Prediction of Preterm Birth
If the investigators could prove that three -dimensional ultrasound measurement of fetal adrenal gland volume can accurately predict the likelihood of preterm birth in patients having symptoms and signs of PTL , they would be…
- Trial name
- NCT02351336
- Testing
- Ultrasound imaging
- Where
- Egypt
- Volunteers
- 78 people
- Sponsor
- Wessam Magdy Abouelghar
Threatened Abortion, Pre-Eclampsia
Progesterone for First Trimester Vaginal Bleeding
The purpose of this study is to investigate whether treatment with progesterone for patients with first trimester vaginal bleeding will alter the rates of obstetrical complications and adverse pregnancy outcomes.
- Conditions
- Threatened Abortion, Pre-Eclampsia, Abruptio Placentae, Fetal Growth Retardation
- Trial name
- NCT01501890
- Testing
- dihydroxyprogesterone caproate
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Pregnant Women Diagnosed With Threatened Preterm Labor
Docosahexaenoic Acid (DHA) Supplementation During Pregnancy Reduces the Risk of Preterm Birth in Threatened Preterm Labor
The goal of this clinical trial is to learn about the effects of Docosahexaenoic acid (DHA) in reducing the incidence of premature birth in threatened preterm labor The main questions it aims to answer are: Can DHA…
- Trial name
- NCT06302023
- Testing
- Docosahexaenoic acid (DHA) 1000 mg
- Where
- Thailand
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Khon Kaen University
Threatened Premature Labor
Vaginal PROgesterone as Maintenance Treatment After an epISode of prEterm Labor (PROMISE Study)
Eligible patients will be informed and asked to enroll in the study at hospital admission. A transvaginal ultrasound examination will be performed to determine cervical length.
- Trial name
- PROMISE (NCT00646802)
- Testing
- Progesterone
- Where
- 12 sites in Spain
- Volunteers
- 265 people
- Sponsor
- Hospital Clinic of Barcelona
Preterm Birth, Immunologic Activity Alteration
Threatened Preterm Birth and Time of Subsequent Delivery -a Prediction Model
This study investigates immunological and clinical markers in threatened preterm birth aiming to create a prediction model for preterm birth.
- Trial name
- NCT03796949
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Linkoeping University
Preterm Labor
Nifedipine Pharmacokinetics and Pharmacodynamics When Used as a Tocolytic in Acute Threatened Preterm Labour
Preterm birth is the leading cause of perinatal mortality and morbidity. According to WHO, 15 million children are born prematurely (gestational age < 37 weeks) in the world each year while 7% of them die because of complications…
- Trial name
- NCT02068404
- Testing
- Nifedipine
- Where
- Switzerland
- Volunteers
- 75 people
- Sponsor
- Chantal Csajka
Obstetric Labor, Premature
Randomized Controlled Trial of Vaginal Progesterone in Women With Threatened Preterm Labor
Prematurity remains the most important single factor in perinatal morbidity and mortality. Unfortunately, the rate of premature delivery is increasing in Canada and is especially high in Alberta with 7.5% of pregnancies ending…
- Trial name
- PROTO (NCT01286246)
- Testing
- Vaginal progesterone
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of Calgary
Preterm Labor, Preterm Birth
The Efficacy of Nifedipine in the Management of Preterm Labor
Preterm labor is one of the problems of obstetrics, and is one of the leading cause of neonatal morbidity and mortality. The incidence of preterm birth is around 7 to 9 %.
- Conditions
- Preterm Labor, Preterm Birth, Preterm Labor Without Delivery, Preterm Labor With Preterm Delivery in Third Trimester
- Trial name
- BOG/TH/PTL (NCT04644354)
- Testing
- Nifedipine 10 mg
- Volunteers
- 444 people
- Sponsor
- Ethem Unal, M.D., PhD, Associate Prof of Surgery & Surgic
PreTerm Labor, Threatened Preterm Labor
Labor Status Monitor for Diagnosing True vs False Labor in Preterm Patients
This is an observational study of pregnant persons in threatened labor. The study device will record electromyography signals, then the signals will be examined to determine who is in true labor and who is in threatened labor.
- Conditions
- PreTerm Labor, Threatened Preterm Labor, Preterm Birth
- Trial name
- NCT06157203
- Testing
- Uterine electromyography
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- PreTeL, Inc
Preterm Birth
The Effect of Low Doses of Prednisone on the Prolongation of Pregnancy in Threatened Preterm Birth
The goal of this clinical trial is to test the effect of a low dose of prednisone in the prevention of preterm labour in singleton pregnancies.
- Trial name
- NCT06103227
- Testing
- Prednisone 5Mg
- Where
- Bosnia and Herzegovina
- Volunteers
- 26 people
- Sponsor
- University of Mostar
Preterm Birth
Association Between EHG and Risk of Preterm Delivery in Women Hospitalized for Threatened Premature Delivery
Preterm delivery accounts for about 10% of deliveries in France. Prematurity is the leading cause of perinatal morbidity and mortality in economically developed countries.
- Trial name
- RACE (NCT03144141)
- Testing
- Electrical recording of uterine activity by EHG either directly at the emergency or at the hospitalization
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Preterm Labor
Ultrasonographic Evaluation of Fetal Adrenal Gland in Cases of Threatened Preterm Labor
Preterm birth continues to be a major public health problem with lasting family and societal repercussions. Despite tremendous research effort, prevention strategies have failed, and the prevalence of preterm birth in the United…
- Trial name
- NCT03251794
- Testing
- three dimensional ultrasound, color Doppler
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Assiut University
Threatened Preterm Labor
Maternal Serum Level of ACTH as a Predictive Marker of Preterm Labor in Patients With Threatened Preterm Labor
The aim of this study is use of ACTH as a predictive marker in patients of threatened preterm labor .
- Trial name
- PTL (NCT01773135)
- Testing
- collection of blood sample and tocolysis adminstration
- Where
- Egypt
- Volunteers
- 262 people
- Sponsor
- Ain Shams Maternity Hospital