Clinical trials: Thromboembolic Disease
Post Thrombotic Syndrome, Chronic Thromboembolic Pulmonary Hypertension
Long Term Outcomes of Venous Thromboembolism
This prospective observational follow-up study is designed to assess the long-term outcomes after Venous thromboembolism (VTE) and to assess the effect of the new oral anticoagulant (NOAC) rivaroxaban on the prevalence of…
- Conditions
- Post Thrombotic Syndrome, Chronic Thromboembolic Pulmonary Hypertension, Venous Thrombosis
- Trial name
- LOVE (NCT02268630)
- Where
- 3 sites in Norway
- Volunteers
- 460 people
- Sponsor
- Ostfold Hospital Trust
Thromboembolic Disease, Gynecological Surgery
An Analysis Into the Cause and Preventional Method of Thromboembolic Disease in Gynecological Surgery
The aim of this cross-sectional study is to describe the specific situations of thromboembolic disease in gynecological surgery and identify the risk factors of it.
- Trial name
- NCT03644992
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Venous Thromboembolism, Deep Venous Thrombosis
Using a Blood Test and Software Tool to Guide Treatment for Venous Thromboembolism
The purpose of this study is to find out whether a software tool, ctDNA/VTE (Venous Thromboembolism) risk score model, is an effective way to predict the likelihood of VTE coming back in people who have received anticoagulant…
- Trial name
- NCT07399977
- Testing
- MSK-ACCESS, ctDNA/VTE Risk Score:
- Where
- 8 sites in United States, Australia
- Volunteers
- 259 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Venous Thromboembolism
Anti Xa Monitoring Low Molecular Weight Heparin on Prevention of Venous Thromboembolism
Venous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism, is a common cardiovascular disease associated with significant morbidity ranging from painful leg swelling, chest pain, shortness of…
- Trial name
- NCT05382481
- Testing
- Peak value anti-Xa, Trough value anti-Xa, Control Group
- Where
- China
- Volunteers
- 858 people
- Sponsor
- Xuanwu Hospital, Beijing
Pulmonary Embolism, Venous Thromboembolism
Residual Pulmonary Vascular Obstruction Index Computed With Ventilation/Perfusion SPECT/CT Imaging to Predict the Risk of Venous Thromboembolism Recurrence in Patients With Pulmonary Embolism (PRONOSPECT)
Major risk after pulmonary embolism (PE) is recurrence, fatal in 10% of patients. Patients with PE can be stratified in 3 groups according to the risk of recurrence : very low risk, high risk or Intermediate risk.
- Trial name
- PRONOSPECT (NCT06372730)
- Testing
- Ventilation/Perfusion Single Photon Emission Computed Tomography (V/Q SPECT/CT)
- Where
- 13 sites in France
- Volunteers
- 665 people
- Sponsor
- University Hospital, Brest
Machine Learning, Chronic Obstructive Pulmonary Disease
Machine Learning-based Models in Prediction of DVT and PTE in AECOPD Patients
Chronic Obstructive Pulmonary Disease (COPD) is a common respiratory system disease characterized by persistent respiratory symptoms and irreversible airflow restriction, which seriously endangers people's health.
- Conditions
- Machine Learning, Chronic Obstructive Pulmonary Disease, Chronic Obstructive Pulmonary Disease With Acute Exacerbation, Unspecified, Pulmonary Thromboembolisms
- Trial name
- NCT05905874
- Testing
- Machine learning-based prediction model
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- West China Hospital
Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia
Management of Platelet Transfusion Therapy in Patients With Blood Cancer or Treatment-Induced Thrombocytopenia
This pilot clinical trial compares the safety of two different platelet transfusion "thresholds" among patients with blood cancer or treatment-induced thrombocytopenia whose condition requires anticoagulant medication (blood…
- Conditions
- Acute Biphenotypic Leukemia, Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, B-Cell Non-Hodgkin Lymphoma
- Trial name
- NCT03195010
- Testing
- Platelet Transfusion
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Fred Hutchinson Cancer Center
Hypertension, Pulmonary
An Open Multiple Dose Titration Study In Patients With Pulmonary Hypertension
This is a study to demonstrate the feasibility of an individual dose titration scheme based on the systolic blood pressure with a dose range from 1.0 mg TID to 2.5 mg TID.
- Trial name
- NCT00454558
- Testing
- Riociguat (Adempas, BAY63-2521)
- Where
- 15 sites in Germany
- Volunteers
- 75 people
- Sponsor
- Bayer
Cancer, Deep Venous Thrombosis
Cohort Study to Identify Cancer Patients at High Risk of Venous Thromboembolism
Cancer patients are at increased risk of deep venous thrombosis and pulmonary embolism, collectively termed venous thromboembolism (VTE).
- Conditions
- Cancer, Deep Venous Thrombosis, Pulmonary Embolism
- Trial name
- MICA (NCT02095925)
- Where
- 7 sites in France, Italy and 2 more
- Volunteers
- 900 people
- Sponsor
- Harry R. Buller
Congenital Heart Defects, Atrial Fibrillation
NOACs for Atrial Tachyarrhythmias in Congenital Heart Disease
Rationale: Adult patients with congenital heart disease (CHD) with atrial tachyarrhythmias need to be anticoagulated. It is not known whether non-vitamin K antagonist oral anticoagulants (NOAC) in this patient group are efficient…
- Conditions
- Congenital Heart Defects, Atrial Fibrillation, Ectopic Atrial Tachycardia
- Trial name
- NOTE (NCT02928133)
- Where
- Netherlands
- Volunteers
- 300 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Transurethral Resection, Wearable Devices
The Effect of Sock Developed with Wearable Technology for TUR Surgery Patients on Hypothermia and Venous Thromboembolism
The aim of this study is to examine the effect of the sock to be developed with wearable technology for patients who will undergo TUR surgery on the development of hypothermia and VTE.
- Conditions
- Transurethral Resection, Wearable Devices, Venous Thromboembolism, Hypothermia
- Trial name
- NCT05887518
- Testing
- Socks Developed with Wearable Technology
- Volunteers
- healthy volunteers welcome
- Sponsor
- Tarsus University
Atrial Fibrillation, Thromboembolism
Investigation on Appropriate Duration of Dabigatran Use After Catheter Ablation for Paroxysmal Atrial Fibrillation in Patients With Low Thromboembolic Risk
The purpose of this study is to investigate the appropriate duration of dabigatran use after radiofrequency catheter ablation for paroxysmal atrial fibrillation in patients with low thromboembolic risk.
- Trial name
- NCT02313584
- Testing
- dabigatran
- Volunteers
- 464 people
- Sponsor
- Korea University
LEVOSIMENDAN, PULMONARY THROMBOENDARTERECTOMY
The Effect of Levosimendan on Pulmonary Artery Pressure and Right Ventricular Function in the Perioperative Period in Patients With CTEPH After Pulmonary Thromboendarterectomy
A single-center pilot prospective randomized placebo-controlled double-blind clinical trial. Study objective - to investigate the efficacy and safety of levosimendan in patients in the perioperative period following pulmonary…
- Conditions
- LEVOSIMENDAN, PULMONARY THROMBOENDARTERECTOMY, Chronic Thromboembolic Pulmonary Hypertension (CTEPH), Pulmonary Hypertension
- Trial name
- LEVO-CTEPH (NCT07914933)
- Testing
- Infusion of levosimendan
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Cerebral Stroke, Thrombosis, Deep Vein
A Study of Adverse Events and Suspected Adverse Drug Reactions in Patients Under Apixaban for Prevention of Stroke and Systemic Embolism With Non-Valvular Atrial Fibrillation and Venous Thromboembolic Events in Patients Who Have Undergone Elective Hip or Knee Replacement Surgery
To characterize and analyze the number, type and incidence of adverse events/suspected adverse drug reactions in patients treated with Apixaban, according to therapeutic indications approved in Mexico.
- Conditions
- Cerebral Stroke, Thrombosis, Deep Vein, Pulmonary Embolism
- Trial name
- NCT03804125
- Sponsor
- Pfizer
Knee Arthroplasty, Total
Factor XI inhibiTion for the Prevention of Venous Thromboembolism in Patients Undergoing Total Knee Arthroplasty
This study was to compare the study drug KN060 to enoxaparin, for the prevention of blood clotting and safety in patients undergoing total knee arthroplasty (TKA).
- Trial name
- NCT06180889
- Testing
- Enoxaparin, KN060 Low, KN060 Middle
- Where
- China
- Volunteers
- 241 people
- Sponsor
- Suzhou Alphamab Co., Ltd.
Aortic Valve Disease, Artificial Heart Valves
Post-market Clinical Monitoring of the Safety and Efficacy of the Aortic Valve Bioprothesis
The goal of this multicenter prospective cohort study is to evaluate the long-term safety and efficacy of clinical outcomes of aortic valve replacement using the "TiAra" prosthesis with or without concomitant procedures.
- Trial name
- TiAra (NCT05998694)
- Where
- Russia
- Volunteers
- 2,000 people
- Sponsor
- Closed Joint-Stock Company NeoCor
Venous Thromboembolism
Long-term Surveillance of Patients With Venous Thromboembolism: a Nationwide Prospective Cohort Study
This observational study aims to establish a prospective nationwide cohort of venous thromboembolism. The main questions it mains to answer are: Which patients with venous thromboembolism should accept long-term anticoagulation…
- Trial name
- NCT06073366
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Chronic Thromboembolic Pulmonary Hypertension (CTEPH), Pulmonary Hypertension
U.S. CTEPH Registry
The U.S. CTEPH Registry is a multicenter, observational, U.S.-based study of the clinical course and treatment of patients diagnosed with chronic thromboembolic pulmonary hypertension (CTEPH), WHO Group IV Classification for…
- Trial name
- NCT02429284
- Where
- United States
- Volunteers
- 754 people
- Sponsor
- University of California, San Diego
Venous Thromboembolism
Medication Use Evaluation for Enoxaparin in Hospitalized COVID-19 Patients
Retrospective chart review to be conducted at Methodist Richardson Medical Center (MRMC) in Richardson, TX. All adult patients hospitalized with COVID-19 on enoxaparin for DVT prophylaxis will be included.
- Trial name
- NCT05226793
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Methodist Health System
Cardiovascular Diseases, Venous Thromboembolism
Study on the Clinical Course Of Pulmonary Embolism
The course of both pulmonary embolism (PE) and one of its more relevant late complications, i.e. chronic thromboembolic pulmonary hypertension (CTEPH) is still substantially unknown.
- Conditions
- Cardiovascular Diseases, Venous Thromboembolism, Pulmonary Hypertension
- Trial name
- SCOPE (NCT01781858)
- Volunteers
- 700 people
- Sponsor
- University of Padova
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