Clinical trials: Thromboembolic Disorders
Atrial Fibrillation, Thromboembolism
Investigation on Appropriate Duration of Dabigatran Use After Catheter Ablation for Paroxysmal Atrial Fibrillation in Patients With Low Thromboembolic Risk
The purpose of this study is to investigate the appropriate duration of dabigatran use after radiofrequency catheter ablation for paroxysmal atrial fibrillation in patients with low thromboembolic risk.
- Trial name
- NCT02313584
- Testing
- dabigatran
- Volunteers
- 464 people
- Sponsor
- Korea University
Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Latent Pulmonary Hypertension (PH) in Chronic Thromboembolic Pulmonary Hypertension (CTEPH )After Endarterectomy and Influence of Exercise and Respiratory Therapy
Severe CTEPH leads to an impaired physical capacity and a restricted quality of life and poor prognosis. Pulmonary endarterectomy represents the best choice as therapy, when the thrombi are located in the central pulmonary…
- Trial name
- NCT00477724
- Testing
- exercise and respiratory therapy, sedentary control group
- Where
- Germany
- Volunteers
- 35 people
- Sponsor
- Heidelberg University
Venous Thromboembolism, Ovarian Neoplasms
Venous Thromboembolic Complications in Ovarian Cancer
Objectives of the study are: To estimate the incidence of venous thromboembolism (VTE) in a cohort of women with suspected ovarian cancer and evaluate changes in the coagulation system in case of benign or malignant disease.
- Conditions
- Venous Thromboembolism, Ovarian Neoplasms, Ovarian Cancer, Deep Vein Thrombosis
- Trial name
- NCT02480790
- Where
- Denmark
- Volunteers
- 98 people
- Sponsor
- Ole Thorlacius-Ussing, MD, DMSc, Professor of Surgery
Thrombosis Embolism, Thromboses, Venous
Cancer-related Venous Thromboembolic Disease - Cohort Study
Venous thromboembolic disease (VTE) is a common (1/1000), potentially serious disease (10% mortality when the clinical presentation is that of pulmonary embolism (PE)).
- Conditions
- Thrombosis Embolism, Thromboses, Venous, Cancer
- Trial name
- CAPE (NCT06393764)
- Testing
- Collection of biological samples
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Brest
Thromboembolic Disease, Gynecological Surgery
An Analysis Into the Cause and Preventional Method of Thromboembolic Disease in Gynecological Surgery
The aim of this cross-sectional study is to describe the specific situations of thromboembolic disease in gynecological surgery and identify the risk factors of it.
- Trial name
- NCT03644992
- Where
- China
- Volunteers
- 54 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Thrombosis
Risk of Developing Antibodies to Heparin-PF4 After Heart Surgery
Heparin is a drug that is widely used to prevent and treat blood clotting. Individuals undergoing cardiopulmonary bypass surgery are administered high doses of heparin, and some of them develop antibodies to the drug.
- Trial name
- HIT (NCT00237328)
- Testing
- Heparin
- Where
- 4 sites in United States
- Volunteers
- 1,015 people
- Sponsor
- Duke University
Thromboembolism, Venous Thromboembolism
Institutional Registry of Thromboembolic Disease
The purpose of this study is to create an institutional registry of Thromboembolic disease through a prospective survey based on epidemiological data, risk factors, diagnosis, prognosis, treatment, monitoring and survival.
- Conditions
- Thromboembolism, Venous Thromboembolism, Pulmonary Embolism
- Trial name
- IRTD (NCT01372514)
- Where
- Argentina
- Volunteers
- 4,500 people
- Sponsor
- Hospital Italiano de Buenos Aires
Venous Thromboembolism
Comparative Study of Prophylactic Agent for Venous Thromboembolism After Total Knee Arthroplasty
The purpose of this study is to compare the efficacy of two prophylactic agent(aspirin 300mg/day and rivaroxaban 10mg/day) for venous thromboembolism after total knee arthroplasty.
- Trial name
- NCT02271399
- Testing
- acetylsalicylic acid, rivaroxaban
- Where
- South Korea
- Volunteers
- 156 people
- Sponsor
- Hanyang University Seoul Hospital
Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Non-Invasive Measurement of Cardiac Output and Stroke Volume in PAH/CTEPH
Pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH) are severe clinical conditions that, despite advances in therapeutics over the past 20 years, lead to serious morbidity and…
- Trial name
- NCT05618093
- Testing
- Non-invasive hemodynamic measurements
- Where
- United States
- Sponsor
- University of California, Los Angeles
Thromboembolism, Vascular Conditions
Evaluation of Contrast Medium Enhanced Post-mortem CT in Virtual Autopsy
The study aims to compare the value of contrast medium enhanced post mortem CT to classic autopsy.
- Trial name
- NCT01541995
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
SARS Virus
Prevalence and Risk Factors for Venous Thromboembolic Events in Critically Ill Patients With COVID-19
The purpose of the study is to assess the frequency of the occurrence of a venous thrombosis in patients with the new Coronavirus disease, who are admitted to the Intensive Care Unit for impending respiratory failure requiring…
- Trial name
- NCT04567927
- Testing
- Ultrasonography
- Where
- Switzerland
- Volunteers
- 80 people
- Sponsor
- Chiesa Alessandro Felice
Placental Vascular Pathologies, Venous Thromboembolism Diseases
Evaluation of an Antithrombotic Therapeutic Strategy in Pregnant Women
The venous thromboembolism is one of the first causes of maternal mortality. Until 2003, only a few recommendations were available on the optimal use of antithrombotic therapy as a preventive measure against thromboembolism in…
- Trial name
- STRATHEGE (NCT00745212)
- Where
- France
- Volunteers
- 2,280 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Postpartum Hemorrhage, Venous Thromboembolism
Haemorrhages and Thromboembolic Venous Disease of the Postpartum
The aim of this study is to evaluate the frequencey and the determinants of postpartum major complications (hemorrhage and thrombosis) up to 3 months after delivery in the maternity hospitals of Finistère (Bretagne - France)
- Trial name
- HEMOTHEPP (NCT02443610)
- Where
- 6 sites in France
- Volunteers
- 20,241 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Glial Tumors, Thrombosis
Usefulness of Thromboelastography as a Predictor of Prognosis in Patients Undergoing Surgery for Glial Tumors and of the Risk of Postoperative Thromboembolic Disease (GliTEM)
The objective of our study is to investigate the clinical significance of thromboelastometric values in the development of thrombotic events and survival in patients with glial tumors, to reduce thromboembolic complications and…
- Conditions
- Glial Tumors, Thrombosis, Pulmonary Embolism (Diagnosis)
- Trial name
- GliTEM (NCT07813377)
- Testing
- Thromboelastometry values: EXTEM CT, MCF, α-angle below the lower limit of normal. Measurement obtained after anesthetic induction. - PT, aPTT, fibrinogen, platelet count. - Thrombin generation. -
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Fundacion Clinic per a la Recerca Biomédica
Lower Limb Trauma, Venous Thromboembolism
Thromboembolic Risk Stratification by TRiP(Cast) Score to Guide Physicians in Preventive Treatment Prescriptions for Patients With Lower Limb Trauma Requiring Brace or castING.
Non-surgical traumas to the lower limbs that require orthopedic immobilisation (plaster or splint) are a frequent reason for going to accident and emergency.
- Conditions
- Lower Limb Trauma, Venous Thromboembolism, Stratification
- Trial name
- CASTING (NCT04064489)
- Testing
- TRIPscore
- Where
- 15 sites in Belgium, France
- Volunteers
- 2,123 people
- Sponsor
- University Hospital, Angers
Chronic Thromboembolic Pulmonary Hypertension, Acute Lung Injury
Lung Protective Ventilation in Pulmonary Thromboendarterectomy (PTE) Patients
Chronic thromboembolic pulmonary hypertension (CTEPH) is caused by unresolved thromboemboli in the pulmonary arteries, which lead to pulmonary hypertension and, left untreated, right heart failure.
- Trial name
- NCT00747045
- Testing
- Ventilation Strategy
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- University of California, San Diego
Hypertension
Ambrisentan for Inoperable Chronic Thromboembolic Pulmonary Hypertension.
It is hypothesised that ambrisentan may provide benefit to subjects with inoperable chronic thromboembolic pulmonary hypertension (CTEPH), where currently no proven or licensed treatment options exist.
- Trial name
- AMBER I (NCT01884675)
- Testing
- Ambrisentan 5 mg
- Where
- 51 sites in United States, Argentina and 14 more
- Volunteers
- 33 people
- Sponsor
- GlaxoSmithKline
Infarction, Middle Cerebral Artery, Ischemic Stroke,
Implantation of Olfactory Ensheathing Cells (OECs)
Recruited patients should receive the endoscopic surgery for picking the olfactory mucosa 1 to 2 months before transplantation. The Olfactory Ensheathing Cells (OECs) will be cultured and expanded under the rule of GTP.
- Conditions
- Infarction, Middle Cerebral Artery, Ischemic Stroke,, Stroke With Hemiparesis,, Thromboembolic Stroke.
- Trial name
- OECs (NCT01327768)
- Testing
- Olfactory ensheathing cells
- Where
- Taiwan
- Volunteers
- 6 people
- Sponsor
- China Medical University Hospital
Pulmonary Embolism, Venous Thromboembolic Disease
Prospective, Multi-center, Single-arm Study to Assess the Safety of Retrieval of the Recovery G2 Filter.
This study was designed to assess the safety of retrieval of the Bard Recovery® G2® Filter System. The G2 filter is an FDA-cleared device for inferior vena caval interruption in patients with pulmonary thromboembolism.
- Trial name
- EVEREST (NCT00556426)
- Testing
- Bard Recovery G2 Filter System
- Volunteers
- 100 people
- Sponsor
- C. R. Bard
Thromboembolic Event
Elaboration of a Prioritization Score for Pharmaceutical Interviews in Patients Treated With Oral Anticoagulants
Oral anticoagulants have a prominent place in the strategy of prevention and treatment of thromboembolic diseases, especially in patients with atrial fibrillation.
- Trial name
- NCT06100380
- Testing
- Survey
- Where
- France
- Volunteers
- 197 people
- Sponsor
- CHU de Reims