Clinical trials: Thromboembolic Event
Venous Thromboembolism (VTE), Total Joint Arthroplasty
Efficacy of Aspirin in Preventing Venous Thromboembolism
Efficacy of aspirin and enoxaparin in preventing venous tromboembolism was compared after total knee or hip arthroplasty.
- Conditions
- Venous Thromboembolism (VTE), Total Joint Arthroplasty, Total Hip Arthroplasty (THA)
- Trial name
- NCT06635317
- Testing
- Aspirin, enoxaparin
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Instituto de Seguridad y Servicios Sociales de los Trabajadores del Estado
Pulmonary Embolism
Is Using Fondaparinux (Blood Thinner) to Treat Lung Clot Cheaper Than Traditional Therapy
This study compares two blood thinners which are both accepted standard cares, fondaparinux and unfractionated heparin (UFH). These drugs are used to prevent the growth of existing blood clots and formation of additional blood…
- Trial name
- NCT00377091
- Testing
- Fondaparinux
- Where
- United States
- Sponsor
- University of Minnesota
Aortic Valve Disease
Transcranial Doppler (TCD) Assessment During Early Anti-thrombotic Therapy After Bioprosthetic Aortic Valve Replacement
The purpose of this study is to determine if there is any difference in the counts of cerebral emboli and platelet function between two prophylactic treatments of thrombosis currently used at University of Ottawa Heart Institute…
- Trial name
- Tissue-Valve (NCT00465218)
- Testing
- Prophylaxis of Thrombosis after aortic valve replacement
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- Ottawa Heart Institute Research Corporation
Recurrent Venous Thrombosis
Risk of Recurrent Venous Thromboembolism After Provoked Venous Thromboembolism
Venous thromboembolism (VTE) is a common disease with an incidence of 1-2/1000 persons per year. VTE is a chronic disease with a considerable risk of recurrence. Patients with unprovoked VTE, i.e.
- Trial name
- AURECpro (NCT04124159)
- Where
- Austria
- Volunteers
- 200 people
- Sponsor
- Medical University of Vienna
Cardiovascular Diseases, Thromboembolism
Risk Factors for Venous Thromboembolism in the Community
To evaluate the trends in the incidence of venous thromboembolism, to determine the risk factors for venous thromboembolism in patients with medical and surgical illness, and to evaluate the efficacy of the anticoagulant therapy…
- Trial name
- NCT00011180
- Where
- United States
- Volunteers
- 385 people
- Sponsor
- Mayo Clinic
Thromboembolism, Anticoagulant-induced Bleeding
Optimization of Management in Patients With Cardiovascular Disease After Lower Limb Joint Replacement
The goal of the study is to evaluate the frequency of cardiovascular and thromboembolic complications in patients with cardiovascular disease after lower limb joint replacement, the influence of known risk factors and strategies…
- Trial name
- NCT06627933
- Testing
- No intervention
- Where
- Russia
- Volunteers
- 1,733 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Deep Vein Thrombosis, Pulmonary Embolism
The Danish Non-vitamin K Antagonist Oral Anticoagulation Study in Patients With Venous Thromboembolism (DANNOAC-VTE)
No randomized head-to-head comparison between the individual Non-vitamin K Antagonist Oral Anticoagulants (NOAC) exists. The DANNOAC-VTE study is a nationwide cluster randomized cross-over study comparing efficacy and safety of…
- Trial name
- DANNOAC-VTE (NCT03129555)
- Testing
- Dabigatran Etexilate Oral Capsule, Rivaroxaban Oral Tablet, Edoxaban Oral Tablet
- Where
- 26 sites in Denmark
- Volunteers
- 5,000 people
- Sponsor
- Herlev and Gentofte Hospital
Venous Thromboembolism (VTE)
Acute Medically Ill VTE Prevention With Extended Duration Betrixaban Study (The APEX Study)
The purpose of this study is to evaluate whether extended prophylaxis with oral betrixaban can prevent blood clots in the leg and lung that sometime occur in patients hospitalized for an acute medical illness and to compare these…
- Trial name
- APEX (NCT01583218)
- Testing
- Betrixaban, Enoxaparin
- Where
- 462 sites in United States, Argentina and 32 more
- Volunteers
- 7,513 people
- Sponsor
- Portola Pharmaceuticals
Venous Thrombosis, Pulmonary Embolism
Study of Rivaroxaban Use and Potential Adverse Outcomes in Routine Clinical Pratice (Netherlands)
This prospective cohort study will provide information about: characteristics of Rivaroxaban use in patients who are prescribed Rivaroxaban for the first time compared to patients who are prescribed Acenocoumarol for the first…
- Conditions
- Venous Thrombosis, Pulmonary Embolism, Atrial Fibrillation, Acute Coronary Syndrome
- Trial name
- NCT01947985
- Testing
- Rivaroxoban (Xarelto, Bay59-7939), Standard of care
- Where
- Netherlands
- Volunteers
- 208,958 people
- Sponsor
- Bayer
Tumor Cells, Circulating, Venous Thrombosis
The Correlation Between Circulatory Tumor Cells and Venous Thrombosis
Research indicates a strong correlation between cancer and thrombosis, with approximately 20% of blood clots in the U.S. being cancer-related, according to CDC data.
- Trial name
- NCT06672250
- Testing
- CTCs/CTMs culture
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Venous Thromboembolism
Treatment of Venous Thromboembolism in Real-Life Patients
In a population of patients with venous thromboembolism and treated with oral anticoagulants (OAC) in routine clinical practice in Denmark this study will describe patients treated with each OAC
- Trial name
- NCT03087474
- Testing
- Non-Interventional
- Volunteers
- 89,383 people
- Sponsor
- Bristol-Myers Squibb
Deep Vein Thrombosis, Pulmonary Embolism
3 Screen Electronic Alert
Evaluation of physician responses to BICS-Clinical Information 3-screen alerts that informs the clinician that his/her patient may be eligible for thromboprophylaxis.
- Conditions
- Deep Vein Thrombosis, Pulmonary Embolism, Cancer
- Trial name
- NCT00550082
- Where
- United States
- Volunteers
- 880 people
- Sponsor
- Brigham and Women's Hospital
Cerebral Embolism
Cerebral Microembolism in the Critically Ill With Acute Kidney Injury
The primary objective of this study is to investigate the impact of continuous renal replacement therapy and intermittent renal replacement therapy on microbubble / cerebral microemboli generation in a cohort of critically ill…
- Trial name
- COMET-AKI (NCT02621749)
- Testing
- Renal replacement therapy
- Where
- Switzerland
- Volunteers
- 66 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Venous Thromboembolism
Pharmacokinetics, Safety and Tolerability of Dabigatran Etexilate Solution in Children 1 to < 2 Years of Age
Study will assess PK/PD parameters and safety and tolerability of the study medication in this age group
- Trial name
- NCT01773174
- Testing
- dabigatran etexilate
- Where
- 8 sites in United States
- Sponsor
- Boehringer Ingelheim
Venous Thromboembolism, Deep Venous Thrombosis
Enoxaparin Metabolism in Reconstructive Surgery Patients
Venous thromboembolism (VTE) is a leading cause of death among hospitalized patients, and is an important patient safety issue in plastic surgery.
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pulmonary Embolus, Reconstructive Surgery
- Trial name
- NCT02411292
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- University of Utah
Venous Thromboembolism
Predicting Bleeding Risk on Anticoagulant Therapy for Venous Thromboembolism
The main objective of the study is to develop or validate a clinical prediction rule for major bleeding in patients on oral anticoagulant therapy who have been safely anticoagulated without bleeding or venous thromboembolism…
- Trial name
- NCT00788736
- Where
- 12 sites in United States, Canada and 1 more
- Volunteers
- 2,537 people
- Sponsor
- Ottawa Hospital Research Institute
Thrombosis, Cardiovascular Diseases
A Phase I SAD/MAD and Liver Effect Study of Vitalangio in Venous Thromboembolism Patients .
The goal of this clinical trial is to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamics of a new drug, Vitalangio1, in healthy male and female volunteers aged 18 to 55 years old.
- Trial name
- NCT07618351
- Testing
- Experimental: Food effect group, Active Comparator: Multiple dose group
- Where
- China
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- Peking University First Hospital
Venous Thromboembolism
Effect of the Genotype on Postoperative DVT
Postoperative Venous Thromboembolism Events (VTE) constitute a major source of morbidity and mortality after surgery. The aim of this study was to investigate whether commonly occurring Single Nucleotide Polymorphisms (SNPs) are…
- Trial name
- NCT04940377
- Where
- Denmark
- Volunteers
- 502,505 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Pulmonary Embolism, Pulmonary Thromboembolism
The PERSEVERE Study
Randomized Controlled Trial of High-Risk Pulmonary Embolism Comparing FlowTriever System vs. Standard of Care
- Trial name
- NCT06588634
- Testing
- FlowTriever System, Standard of Care
- Where
- 33 sites in United States, France and 4 more
- Volunteers
- 200 people
- Sponsor
- Inari Medical
Acute Exacerbation Copd, Venous Thromboembolism
Study of Prophylactic Effect of Rivaroxaban on Venous Thromboembolism in AECOPD
AECOPD increases the risk of VTE.VTE prevention is a long way to go for high-risk VTE patients in China.The incidence of AECOPD complicated with VTE in Asian population is high and the mortality rate is high.Rivaroxaban, a new…
- Trial name
- SUPREME (NCT03277001)
- Testing
- Rivaroxaban, Enoxaparin
- Where
- China
- Volunteers
- 438 people
- Sponsor
- Huashan Hospital