Clinical trials: Thromboembolism
Prevention of Venous Thromboembolism
Efficacy And Safety Of Unfractionated Heparin In Patients With Cardiovascular Surgery Using Cardiopulmonary Bypass
The primary objective of this study is to verify, through a randomized, blinded, parallel clinical trial, the efficacy of bovine heparin from Bergamo Laboratory ACTIPARIN ® product when compared to porcine heparin APP…
- Trial name
- NCT01072747
- Testing
- bovine heparin, Porcine heparin
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- Azidus Brasil
Prevention of Venous Thromboembolism
Efficacy And Safety Of Heparin In Patients With Cardiovascular Surgery Using Cardiopulmonary Bypass
The primary objective of this study is to verify, through a randomized, blinded, parallel clinical trial, the efficacy of bovine heparin from Eurofarma Laboratory product when compared to porcine heparin APP Pharmaceutical in…
- Trial name
- NCT01072955
- Testing
- Bovine Heparin, Porcine heparin
- Where
- Brazil
- Volunteers
- 104 people
- Sponsor
- Azidus Brasil
Venous Thromboembolism
Long-term Surveillance of Patients With Venous Thromboembolism: a Nationwide Prospective Cohort Study
This observational study aims to establish a prospective nationwide cohort of venous thromboembolism. The main questions it mains to answer are: Which patients with venous thromboembolism should accept long-term anticoagulation…
- Trial name
- NCT06073366
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- China National Center for Cardiovascular Diseases
Thromboembolism, Postpartum DVT
Impact of Prophylactic Low-molecular Weight Heparin Dosing on Clotting Parameters Following Cesarean Delivery
The aim of this study is to evaluate the efficacy of two dosing regimens of low molecular weight heparin (LMWH) to reach prophylactic anti-factor Xa levels in post-cesarean delivery women.
- Conditions
- Thromboembolism, Postpartum DVT, Thrombosis
- Trial name
- NCT04305756
- Testing
- Enoxaparin
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- University of Utah
Deep Vein Thrombosis, Pulmonary Embolism
Study of an Investigational Drug for the Prevention of Thrombosis-related Events Following Hip Replacement Surgery (ADVANCE-3)
The purpose of this study is to learn whether apixaban can prevent the blood clots in the leg (deep vein thrombosis) and lung (pulmonary embolism) that sometimes occur after hip replacement surgery and to learn how apixaban…
- Trial name
- NCT00423319
- Testing
- Enoxaparin, Apixaban
- Where
- 143 sites in United States, Argentina and 19 more
- Volunteers
- 5,407 people
- Sponsor
- Bristol-Myers Squibb
Esophageal Neoplasms, Thrombosis
Thromboprophylaxis in Oesophageal Cancer Patients
The purpose of the study is to examine the efficacy and safety of prolonged thromboprophylactic treatment with Fragmin® in oesophageal cancer patients undergoing intended curative surgery.
- Conditions
- Esophageal Neoplasms, Thrombosis, Thromboembolism
- Trial name
- TOP-RCT (NCT05067153)
- Testing
- Fragmin 5000 UNT in 0.2 ML Prefilled Syringe
- Where
- Denmark
- Volunteers
- 100 people
- Sponsor
- University of Aarhus
Cancer, Thrombosis
Anticoagulation Length in Cancer Associated Thrombosis
This is a two year, multicentre, mixed methods feasibility study including a randomised controlled two-arm interventional trial, a nested qualitative study, focus groups and a United Kingdom (UK) wide survey exercise.
- Conditions
- Cancer, Thrombosis, Venous Thromboembolism, Deep Vein Thrombosis
- Trial name
- ALICAT (NCT01817257)
- Testing
- Low Molecular Weight Heparin (LMWH)
- Where
- 5 sites in United Kingdom
- Volunteers
- 2 people
- Sponsor
- Cardiff University
Venous Thromboembolism
A Comparison of Extended Versus Conventional Duration of Enoxaparin Prophylaxis (i.e., Preventive Treatment) for Venous Thromboembolism (VTE, i.e., Blood Clots in the Veins) and Bleeding Event Risk in a Population With Acute Medical Illness
Venous Thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is associated with an increase in risk of mortality and long-term disability and is a major contributor to global disease burden.
- Trial name
- NCT05819112
- Where
- United States
- Volunteers
- 14,799 people
- Sponsor
- Sanofi
Thromboembolism, Deep Vein Thrombosis
Prophylaxis In Venous Thromboembolism In Primary Care, A Pilot Study
The primary objective was to study the clinical benefit with dalteparin sodium in thromboprophylaxis in primary care medical subjects.
- Conditions
- Thromboembolism, Deep Vein Thrombosis, Dalteparin
- Trial name
- NCT00655122
- Testing
- Dalteparin sodium
- Where
- 5 sites in Spain
- Volunteers
- 8 people
- Sponsor
- Pfizer
Gastrointestinal Neoplasms, Thromboembolic Event
Comparison of Thromboembolic Events in Patients Undergoing Thromboprophylactic Treatment With ENOXA® vs Lovenox®
Prospective, monocentric, randomized, parallel group, rater-blinded study using two formulations of Enoxaparin sodium (ENOXA® vs LOVENOX®) to compare the thromboembolic events (symptomatic and asymptomatic) in patients undergoing…
- Trial name
- ENOXACARE (NCT02444572)
- Testing
- Enoxaparin 4000 IU
- Where
- Tunisia
- Volunteers
- 168 people
- Sponsor
- Les Laboratoires des Médicaments Stériles
Venous Thromboembolism, Lung Neoplasm
Prophylaxis of Venous Thromboembolism in Advanced Lung Cancer (PROVE)
Prospective randomized open multicenter trial with blinded adjudication of endpoints to assess the efficacy of six-month low-dose LMWH (Low Molecular Weight Heparin) for the prevention of symptomatic or incidental VTE in patients…
- Trial name
- PROVE (NCT03090880)
- Testing
- Tinzaparin Sodium
- Where
- 27 sites in France
- Volunteers
- 59 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thromboembolism
A Study to Evaluate the Efficacy and Safety of Fondaparinux Sodium When Used With Intermittent Pneumatic Compression to Prevent Venous Thromboembolic (IPC) Versus IPC Alone for the Prevention of Venous Thromboembolic Events in Subjects at Increased Risk Undergoing Major Abdominal Surgery (APOLLO).
This is a multicentre, randomized, double-blind, placebo controlled study. During this study all the patients will receive background venous thromboembolism (VTE) mechanical prophylaxis with intermittent pneumatic compression…
- Trial name
- NCT00038961
- Testing
- fondaparinux sodium
- Volunteers
- 1,309 people
- Sponsor
- GlaxoSmithKline
Venous Thrombosis
Evaluation of the Duration of Therapy for Thrombosis in Children
The Kids-DOTT trial is a randomized controlled clinical trial whose primary objective is to evaluate non-inferiority of shortened-duration (6 weeks) versus conventional-duration (3 months) anticoagulation in children with…
- Trial name
- Kids-DOTT (NCT00687882)
- Testing
- Shortened duration (6 weeks) of anticoagulant therapy, Conventional duration (3 months) of anticoagulant therapy, No Intervention
- Where
- 63 sites in United States, Australia and 4 more
- Volunteers
- 532 people
- Sponsor
- Johns Hopkins All Children's Hospital
Cerebral Vein Thrombosis
Rivaroxaban vs. Warfarin in CVT Treatment
Cerebral venous thrombosis (CVT) is an uncommon venous-type of stroke tends to affect younger patients with somewhat different risk factors and much better outcome compared to arterial strokes.
- Trial name
- RWCVT (NCT04569279)
- Testing
- Rivaroxaban, Warfarin
- Where
- Syria
- Volunteers
- 71 people
- Sponsor
- Damascus University
Venous Thromboembolism
Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Thromboembolism in Patients Undergoing Hip Fracture Surgery
The primary objective was to compare the efficacy of once daily [q.d] subcutaneous [s.c.] injections of Semuloparin sodium (AVE5026) with q.d. s.c.
- Trial name
- SAVE-HIP2 (NCT00721760)
- Testing
- Enoxaparin sodium, Semuloparin sodium
- Where
- 25 sites in United States, Argentina and 23 more
- Volunteers
- 1,003 people
- Sponsor
- Sanofi
Venous Thromboembolic Disease, Deep Vein Thrombosis
Venous Thromboembolic Prophylaxis After Trauma: Three Times a Day Unfractionated Heparin Versus Twice a Day Enoxaparin
The rate of venous thromboembolic events in trauma patients at high risk for deep vein thrombosis and pulmonary embolism receiving low dose unfractionated heparin every 8 hours will be equivalent or less than a similar group of…
- Conditions
- Venous Thromboembolic Disease, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT01729559
- Testing
- 5000 Units unfractionated Heparin Q 8 hr, 30mg enoxaparin Q12 hr
- Where
- United States
- Volunteers
- 495 people
- Sponsor
- Scripps Health
Venous Thromboembolism, Deep Venous Thrombosis
The Protrieve PROTECTOR Study
The Protrieve PROTECTOR Study is a prospective, single-arm, multicenter study of the Protrieve Sheath.
- Trial name
- PROTECTOR (NCT06495996)
- Testing
- Percutaneous mechanical thrombectomy (PMT)
- Where
- 15 sites in United States
- Volunteers
- 66 people
- Sponsor
- Inari Medical
Venous Thromboembolism (VTE), Deep Vein Thrombosis (DVT)
Cancer Venous Thromboembolism (VTE)
The primary objective is to demonstrate the non-inferiority of edoxaban (preceded by a short course of LMWH) compared with dalteparin for the prevention of the combined outcome of recurrent venous thromboembolism (VTE) or major…
- Conditions
- Venous Thromboembolism (VTE), Deep Vein Thrombosis (DVT), Pulmonary Embolism (PE), Cancer
- Trial name
- NCT02073682
- Testing
- Edoxaban, Dalteparin, Low molecular weight heparin
- Where
- 9 sites in United States, Belgium and 4 more
- Volunteers
- 1,046 people
- Sponsor
- Daiichi Sankyo
Venous Thromboembolism
Chinese Community Inpatient Thromboembolism
This study is a multicenter cross-sectional study conducted at 20 centers. Data of existing inpatients in 20 community hospitals were collected.
- Trial name
- COMET (NCT06168331)
- Where
- 2 sites in China
- Volunteers
- 1,152 people
- Sponsor
- RenJi Hospital
COVID 19, Thromboembolic and Bleeding Complications
Thromboembolic Complications in Mild Covid-19 Cases
The aim of the study is to investigate the frequency of thromboembolic complications and the factors influencing them in COVID-19 cases that did not require hospitalization.
- Conditions
- COVID 19, Thromboembolic and Bleeding Complications, Thromboembolism, Venous, Post COVID-19
- Trial name
- NCT06695377
- Where
- Turkey (Türkiye)
- Volunteers
- 961 people, healthy volunteers welcome
- Sponsor
- Marmara University Pendik Training and Research Hospital