Clinical trials: Thromboprophylaxis
Venous Thrombosis Due to Central Venous Access Device (Disorder), Prophylactic Anticoagulation
Prophylactic Anticoagulation for Catheter-related Thrombosis
The main objective of this study is to compare the efficacy and safety of aspirin, low molecule heparin and rivaroxaban for preventing catheter-related thrombosis in middle-to-high-risk ambulatory patients with cancer and…
- Conditions
- Venous Thrombosis Due to Central Venous Access Device (Disorder), Prophylactic Anticoagulation, Patients With Tumor
- Trial name
- NCT04256525
- Testing
- Rivaroxaban 10mg, Aspirin 100mg, low molecule heparin
- Where
- 28 sites in China
- Volunteers
- 1,640 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Deep Vein Thrombosis, Pulmonary Embolism
Prophylaxis of Thromboembolic Complications Trial: Thromboprophylaxis Needed in Below Knee Plaster Cast Immobilization for Ankle and Foot Fractures
Objective: The purpose of this study is to determine the need for thromboprophylaxis in patients with a fracture of the lower extremity being treated conservatively in a below-knee plaster cast and to assess if both of the two…
- Trial name
- PROTECT (NCT00881088)
- Testing
- Nadroparin, Fondaparinux
- Where
- 5 sites in Netherlands
- Volunteers
- 669 people
- Sponsor
- Red Cross Hospital Beverwijk
Covid19, Thromboembolism
Dosing of Thromboprophylaxis and Mortality in Critically Ill COVID-19 Patients
The aim of the study is to associate dose of thromboprophylaxis with outcome in critically ill COVID-19 patients. This will be done by associating dose of thromboprophylaxis with 28-day mortality, survival outside ICU…
- Trial name
- NCT04593654
- Testing
- Dose of tinzaparin or dalteparin
- Where
- Sweden
- Volunteers
- 257 people
- Sponsor
- Karolinska Institutet
Deep Vein Thrombosis, Pulmonary Embolism
Evaluation of Thromboprophylaxis Appropriateness in Hospitalized Medical Patients
Considering observational studies that suggested a relationship between acutely ill medical patients and venous thromboembolism (VTE), interventional studies with anticoagulant medications indicated a marked decline in VTE during…
- Conditions
- Deep Vein Thrombosis, Pulmonary Embolism, Venous Thromboses
- Trial name
- NCT05449808
- Where
- Iraq
- Volunteers
- 320 people
- Sponsor
- Al-Esraa University College
Kawasaki Disease, Coronary Artery Aneurysm
Rivaroxaban for Children Aged Over 2 Years With Giant Coronary Artery Aneurysms After Kawasaki Disease
Based on population pharmacokinetic model-based simulation, a 15 mg-equivalent, age-, and bodyweight-adjusted dosing regimen for Chinese children with giant coronary artery aneurysms after acute Kawasaki disease was proposed.
- Trial name
- RIVA-KG (NCT05643651)
- Testing
- Rivaroxaban Oral Tablet [Xarelto], Aspirin or Clopidogrel, Warfarin
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Children's Hospital of Fudan University
Venous Thromboembolism
An Observational Study On The Safety And Tolerability Of Prolonged Thrombosis Prophylaxis With Fragmin®
The objective of this study is to observe the safety, tolerability, and compliance in the use of Fragmin® for prolonged thromboprophylaxis in post-surgery high-risk orthopedic patients.
- Trial name
- NCT01046903
- Testing
- Fragmin® (Dalteparin Sodium)
- Volunteers
- 503 people
- Sponsor
- Pfizer
Antiphospholipid Syndrome
Rivaroxaban for Patients With Antiphospholipid Syndrome
Long-term anticoagulation is widely used for secondary thromboprophylaxis in the antiphospholipid syndrome (APS) due to the high risk of recurrent events.
- Trial name
- NCT02926170
- Testing
- Rivaroxaban, acenocumarol
- Where
- Spain
- Volunteers
- 190 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Venous Thromboembolism
Electronic Alert System for Improving Thromboprophylaxis in Hospitalized Medical Patients
The investigators aim to investigate whether a computer-based alert system in the electronic patient chart and order entry system using the Geneva Risk Score as clinical decision support tool to estimate the risk of venous…
- Trial name
- NCT03124017
- Testing
- Electronic alert and the Geneva Risk Score calculation tool issued in the electronic patient chart
- Where
- Switzerland
- Volunteers
- 1,756 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Venous Thromboembolism
Prospective Study on Preoperative Versus Postoperative Venous Thromboprophylaxis in Patients Undergoing Major Colorectal Surgery
Patients undergoing major colorectal surgery are at increased risk for VTE (deep venous thrombosis) compared with patients undergoing other general surgical procedures (Bergqvist et al. Dis. Col. Rectum.
- Trial name
- NCT01976988
- Testing
- Heparin
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- Cedars-Sinai Medical Center
Venous Thromboembolism
Evaluation of AVE5026 as Compared to Placebo for the Extended Prophylaxis of Venous Thromboembolism in Patients Having Undergone Hip Fracture Surgery
The primary objective is to evaluate the efficacy of once daily (QD) subcutaneous (SC) injections of Semuloparin sodium (AVE5026) versus placebo for 3 additional weeks following an initial 7 to 10-day venous thromboprophylaxis…
- Trial name
- SAVE-HIP3 (NCT00709904)
- Testing
- Open-label Semuloparin sodium, Semuloparin sodium
- Where
- 16 sites in United States, Belarus and 14 more
- Volunteers
- 469 people
- Sponsor
- Sanofi
Lower Limb Injury, Pulmonary Embolism
Assessment of the Impact of TIP Score on Thromboprophylaxis in Patients With Non-surgical Lower Leg Trauma.
Traumatic lesions are the leading causes of admission to the emergency center (39%), isolated non-surgical lower limbs trauma are in the foreground.
- Conditions
- Lower Limb Injury, Pulmonary Embolism, Venous Thromboses
- Trial name
- EvaTIP (NCT03089255)
- Where
- France
- Volunteers
- 196 people
- Sponsor
- University Hospital, Angers
Bleeding, Venous Thromboembolism
Venous Thromboembolism Prophylaxis Post Cesarean Section
Pregnancy is associated with an overall 5-10 fold increased risk of venous thromboembolism (VTE). VTE remains the most common cause of maternal death in the developed world.
- Trial name
- PROCS (NCT01321788)
- Testing
- TINZAPARIN
- Where
- Saudi Arabia
- Volunteers
- 300 people
- Sponsor
- King Saud University
Peripheral Arterial Disease (PAD), Amputation
Personalizing Thromboprophylaxis for Patients With Peripheral Artery Disease
The goal of this clinical trial is to determine whether a personalised blood clot prevention plan is more effective than standard treatment in adults with peripheral artery disease (PAD) who have undergone a procedure to restore…
- Conditions
- Peripheral Arterial Disease (PAD), Amputation, Thrombosis, Thrombosis (Stent Thrombosis)
- Trial name
- NCT07613840
- Testing
- Aspirin, Clopidogrel, Ticagrelor
- Where
- 2 sites in United States
- Volunteers
- 484 people
- Sponsor
- Massachusetts General Hospital
Transcatheter Aortic Valve Replacement, Transcatheter Heart Valve Thrombosis
Low-dose Colchicine for Thromboprophylaxis After Transcatheter Aortic Valve Replacement
This prospective, randomized, open-label study aims to evaluate the efficacy and safety of low-dose colchicine (0.5 mg daily) in reducing transcatheter heart valve (THV) thrombosis in patients after TAVR.
- Conditions
- Transcatheter Aortic Valve Replacement, Transcatheter Heart Valve Thrombosis, Anti-inflammatory Therapy
- Trial name
- LoDoCo-TAVR (NCT07411768)
- Testing
- Colchicine, Standard Care
- Where
- China
- Volunteers
- 116 people
- Sponsor
- China National Center for Cardiovascular Diseases
Thromboses, Venous, Lower Limb Injury
A Prospective Study to Assess the Risk Factors That Contribute to Thrombosis in Patients With Lower Limb Injuries.
This study is aimed at identifying patients at high risk for Venous Thrombo-Embolism (VTE) (clots in the veins of legs or clots in the lungs) who have lower limb injuries treated with immobilisation of the lower limb.
- Trial name
- TILLIRI (NCT04608591)
- Where
- Ireland
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Total Knee Arthroplasty, Venous Thromboembolism
Comparison of DOACs and LMWH for Thromboprophylaxis After Total Knee Arthroplasty
Yes. For these two fields, I would enter the following in English, based on your study protocol. 1. Brief Summary Copy and paste: This study aims to compare three thromboprophylaxis regimens in adults undergoing primary total…
- Trial name
- DOLOTHROK (NCT07869615)
- Testing
- Apixaban, Rivaroxaban, Enoxaparin (LMWH)
- Where
- Tunisia
- Volunteers
- 138 people
- Sponsor
- Military Hospital of Tunis
Multiple Myeloma, Venous Thromboembolism (VTE)
Aspirin vs. Rivaroxaban for Thromboprophylaxis in Multiple Myeloma
The goal of this clinical trial is to compare the efficacy and safety of aspirin versus rivaroxaban for thromboprophylaxis in newly diagnosed multiple myeloma patients receiving immunomodulatory drug (IMiD)-based therapy.
- Trial name
- NCT07907211
- Testing
- Aspirin, Rivaroxaban
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Chen Lijuan
Thromboprophylaxis, Critical Illness
Pharmacokinetic Profiles of Subcutaneous Enoxaparin for Thromboprophylaxis in Critically Ill Patients With Renal Failure Treated or Not With Continuous Veno-veinous Hemofiltration.
Thromboprophylaxis is recommended for critically ill patients without contraindications and is usually achieved by the subcutaneous daily administration of a low dose of low molecular weight heparin (LMWH).
- Conditions
- Thromboprophylaxis, Critical Illness, Intensive Care (ICU)
- Trial name
- AKI-ENOXA (NCT07384598)
- Testing
- Anti-Xa profiles after the subcutaneous administration of a prophylactic dose of enoxaparin
- Volunteers
- 60 people
- Sponsor
- Clinique Saint Pierre Ottignies
Venous Thromboembolic Diseases
Comparison of 2 Low Molecular Weight Heparin as a Thromboprophylaxis Postpartum
The use of a new generation low molecular weight heparin (Bemiparin)and the well known LMWH (Enoxaparin) after Caesarean sections and vaginal deliveries in a risky group patients for venous thrombosis.
- Trial name
- NCT01588171
- Testing
- Bemiparin, Enoxaparin
- Where
- Iraq
- Volunteers
- 7,020 people
- Sponsor
- Hawler Medical University
Venous Thormboembolism
Study Of Weight-Based Versus Standard Dose Enoxaparin Thromboprophylaxis In High-Risk Hospitalized Cancer Patients
Hospitalized patients with histologically or cytologically confirmed diagnosis of solid tumor malignancy, lymphoma, or multiple myeloma and who are at high risk for a venous thromboembolism will be randomized to standard dose…
- Trial name
- NCT02706249
- Testing
- Enoxaparin
- Where
- 2 sites in United States
- Volunteers
- 50 people
- Sponsor
- Dana-Farber Cancer Institute