Clinical trials: Thromboprophylaxis
Thrombosis, Arterial Occlusive Diseases
Thromboelastography With Platelet Mapping to Guide Antiplatelet Therapy After Lower Extremity Revascularization
The goal of this clinical trial is to learn if a blood clotting test called thromboelastography with platelet mapping (TEG-PM) can guide blood-thinning medication decisions in adults more than 60 years and older with peripheral…
- Conditions
- Thrombosis, Arterial Occlusive Diseases, Thromboelastography (TEG), Peripheral Arterial Disease(PAD)
- Trial name
- TARGET (NCT07597239)
- Testing
- Aspirin, Clopidogrel, Ticagrelor
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- Massachusetts General Hospital
Venous Thromboembolism
Thromboprophylaxis in Critically Ill Patients
Intensive care patients are at high risk to develop deep venous thrombosis and pulmonary embolism. Despite anticoagulation with heparin 7% of ICU patients suffer from this serious complication.
- Trial name
- NCT00437697
- Testing
- dalteparin
- Where
- Austria
- Volunteers
- 90 people
- Sponsor
- Medical University of Vienna
COVID-19
Prevalence of Severe Bleeding in COVID-19 Patients Treated With Higher Than Recommended Thromboprophylaxis Doses
The main objectives are: To establish the prevalence of major bleeding in patients treated with higher than recommended thromboprophylaxis doses. To identify variables associated to higher risk of bleeding.
- Trial name
- BLEEDING (NCT04380779)
- Where
- Spain
- Volunteers
- 2,430 people
- Sponsor
- Manuel Monreal
Venous Thromboembolism, Thromboprophylaxis
Aspirin and Enoxaparin for VTE in Trauma
The purpose of this study is to determine if the addition of antiplatelet therapy (i.e. aspirin) to low-molecular-weight-heparin (i.e.
- Conditions
- Venous Thromboembolism, Thromboprophylaxis, Trauma
- Trial name
- NCT02396732
- Testing
- Aspirin, Enoxaparin
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- University of Miami
Hip Fractures
HIP Fracture Oral thromboPROphylaxis (Hip PRO Pilot)
As our Canadian population ages, hip fractures in these older adults are becoming very common. The best treatment for the majority of these injuries is urgent treatment with surgery.
- Trial name
- HIP PRO Pilot (NCT05775965)
- Testing
- Rivaroxaban 10mg, acetylsalicylic acid (ASA) 81mg Oral Tablet
- Where
- 3 sites in Canada
- Volunteers
- 250 people
- Sponsor
- University of Calgary
COVID-19
Effect of Anticoagulation Therapy on Clinical Outcomes in COVID-19
Patients with moderate to severe COVID-19 present a very high risk of thromboembolic disease.This multicenter, prospective, randomized, event-driven study evaluates rivaroxaban compared with standard of care with…
- Trial name
- COVID-PREVENT (NCT04416048)
- Testing
- Rivaroxaban, Standard Of Care (SOC)
- Where
- 24 sites in Germany
- Volunteers
- 111 people
- Sponsor
- Charite University, Berlin, Germany
Venous Thrombosis Deep (Limbs), Venous Insufficiency (Chronic)(Peripheral)
Apixaban vs Rivaroxaban vs No Anticoagulant to Prevent EHIT After Great Saphenous Vein Laser Ablation
Endothermal heat-induced thrombosis (EHIT) is a thrombotic complication specific to endovenous thermal ablation of the great saphenous vein (GSV), for which no prophylactic regimen is standardized.
- Conditions
- Venous Thrombosis Deep (Limbs), Venous Insufficiency (Chronic)(Peripheral), Varicose Veins Leg, Venous Thrombosis
- Trial name
- NCT07699796
- Testing
- Apixaban, Rivaroxaban
- Where
- United States
- Volunteers
- 564 people
- Sponsor
- Heart, Artery, and Vein Center of Fresno
Thromboprophylaxis in Hospitalized Obese Patients
Adjusted Value of Thromboprophylaxis in Hospitalized Obese Patients: A Comparative Study of Two Regimens of Enoxaparin
Venous thromboembolism (VTE), deep vein thrombosis (DVT) or pulmonary embolism (PE) is a common medical condition encountered during hospitalization in a medical environment.
- Trial name
- ITOHENOX (NCT01707732)
- Testing
- Enoxaparin
- Where
- France
- Volunteers
- 92 people
- Sponsor
- University Hospital, Rouen
Deep Venous Thrombosis
Catheter-Related Early Thromboprophylaxis With Enoxaparin (CRETE) Trial
The purpose of this phase 2a, multi-center, randomized controlled study, is to explore the efficacy of early prophylaxis against catheter-associated deep venous thrombosis (CADVT) in critically ill children.
- Trial name
- CRETE (NCT03003390)
- Testing
- Enoxaparin
- Where
- 6 sites in United States
- Volunteers
- 51 people
- Sponsor
- Yale University
Venous Thromboembolism (VTE), Post Partum Women
Prevention of Postpartum Venous Thromboembolism in Women at Intermediate Risk
Venous thromboembolism (VTE) is currently the second cause of death in women of reproductive age worldwide. The incidence of VTE during pregnancy is 1.2 to 1.4/1000 women, half of VTE occurring during postpartum and as PE in…
- Trial name
- MUM-VTE (NCT06845423)
- Testing
- Low molecular weight heparin
- Where
- 18 sites in France
- Volunteers
- 2,400 people
- Sponsor
- University Hospital, Brest
Venous Thromboembolism, Urologic Cancer
VTE Prevention With Rivaroxaban in Genitourinary Cancer Patients Receiving Systemic Therapy
Patients with genitourinary cancers (ex: bladder, testicular, kidney) are at high risk of developing blood clots if they receive systemic therapy (ex: chemotherapy, immunotherapy).
- Trial name
- PREVENT-GU (NCT05920343)
- Testing
- Rivaroxaban 10 MG
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Ottawa Hospital Research Institute
Nephrotic Syndrome
Anti-Xa Activity of Enoxaparin for Prevention of Venous Thromboembolism in Severe Nephrotic Syndrome.
The primary objective is to test the hypothesis that enoxaparin efficacy is reduced in severe nephrotic syndrome. Another purpose is to compare two dosing regimens.
- Trial name
- ENOX-inNS (NCT04558892)
- Testing
- Enoxaparin
- Where
- Poland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Military Institute od Medicine National Research Institute