Clinical trials: Thrombosis, Venous
Pulmonary Embolism, Venous Thromboembolism
Prognostic Value of 2026 AHA/ACC Clinical Categorization in Acute Pulmonary Embolism Patients Presenting to the Emergency Department
Background: The 2026 American Heart Association/American College of Cardiology (AHA/ACC) Pulmonary Embolism Guideline (Creager et al., Circulation 2026) introduced a novel five-category (A-E) clinical classification system with…
- Conditions
- Pulmonary Embolism, Venous Thromboembolism, Acute Pulmonary Embolism
- Trial name
- APEX-2026 (NCT07805616)
- Testing
- 2026 AHA/ACC Clinical Risk Categorization
- Where
- Turkey (Türkiye)
- Volunteers
- 600 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Thromboprophylaxis, Thromboembolism, Venous
Thromboembolic Risk Assessment in Patients Admitted With Acute Medical Diseases to Conventional and At Home Hospitalization
The thromboembolic disease is a common complication of patients admitted to conventional hospitalization units. To prevent such complications, thromboprophylaxis is indicated in high-risk patients identified with validated…
- Conditions
- Thromboprophylaxis, Thromboembolism, Venous, Atrial Fibrillation, Physical Inactivity
- Trial name
- TROMBODOM (NCT06110949)
- Testing
- Triaxial accelerometry
- Where
- Spain
- Volunteers
- 1,953 people
- Sponsor
- Universidad Pública de Navarra
Breast Cancer, Upper Extremity Deep Vein Thrombosis, Secondary
Determination of Predictive Value of Echography Doppler Abnormalities
In order to avoid to use a traumatic and iatrogenic examen (phlebography), the purpose of the study is to validate echography doppler in the diagnosis of asymptomatic related catheter related thrombosis.
- Trial name
- CAVECCAS (NCT00714909)
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Venous Thromboembolism, Risk Factor, Cardiovascular
Distribution of Risk Factors for Venous Thromboembolism in Blood Donors
Venous thromboembolism occurs with an incidence of about 1 per 1000 per year in adults . The main consequences are death, recurrence, post-thrombotic syndrome and major bleeding due to anticoagulation.
- Conditions
- Venous Thromboembolism, Risk Factor, Cardiovascular, Blood Type
- Trial name
- ANEMONE (NCT03282747)
- Testing
- no intervention
- Where
- Italy
- Volunteers
- 10,000 people, healthy volunteers welcome
- Sponsor
- Casa Sollievo della Sofferenza IRCCS
Retinal Vein Occlusion
Minocycline to Treat Central Retinal Vein Occlusion
Background: Central retinal vein occlusion (CRVO) is a blockage of the main vein that carries blood away from the retina in the back of the eye.
- Trial name
- NCT01468844
- Testing
- Minocycline, Bevacizumab
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 6 people
- Sponsor
- National Eye Institute (NEI)
Retinal Vein Occlusion, Diabetic Macular Edema
Exploratory Study of KPI-121 Effect on Intra- or Subretinal Fluid Due to Retinal Vein Occlusion/Diabetic Macular Edema
The primary objectives of the study are to evaluate the safety and effect of KPI-121 0.25% ophthalmic suspension and KPI-121 1.0% ophthalmic suspension on intraretinal or subretinal fluid secondary to Retinal Vein Occlusion or…
- Trial name
- Molokini (NCT02245516)
- Testing
- KPI-121 0.25% Ophthalmic Suspension, KPI-121 1.0% Ophthalmic Suspension
- Where
- 2 sites in United States
- Volunteers
- 16 people
- Sponsor
- Kala Pharmaceuticals, Inc.
Deep Vein Thrombosis, Venous Thrombosis
Echo-Doppler Assessment of the Occurrence of Asymptomatic DVT in Orthopedic Replacement Surgery Under Enoxaparin
The objectives of the study are: o Objective ultrasound: Determine the presence or absence of subclinical DVT in practicing ultrasound-Doppler Day7 and Day35, patients who underwent TKA or THA o Clinical objective To evaluate the…
- Conditions
- Deep Vein Thrombosis, Venous Thrombosis, Adverse Effect of Anticoagulants
- Trial name
- PRENOXA (NCT01354704)
- Testing
- Enoxaparin
- Where
- Tunisia
- Volunteers
- 153 people
- Sponsor
- Les Laboratoires des Médicaments Stériles
Venous Thromboembolism, Venous Thromboses
Leiden Thrombosis Recurrence Risk Prevention
The goal of this clinical trial is to evaluate tailored duration of long-term anticoagulant treatment after a first venous thromboembolism based on individualized risk assessments of recurrent VTE and major bleeding risks.
- Conditions
- Venous Thromboembolism, Venous Thromboses, Pulmonary Embolism, Deep Vein Thrombosis
- Trial name
- L-TRRiP (NCT06087952)
- Testing
- Randomised treatment advice (discontinue vs continue after 3 months), VTE-BLEED score, L-TRRiP score
- Where
- 19 sites in Netherlands
- Volunteers
- 608 people
- Sponsor
- Leiden University Medical Center
Acute Myocardial Infarction, STEMI
Multi-modality Imaging in Acute Myocardial Infarction
The goal of this study is to use three (3) different imaging techniques:Fractional Flow Reserve (FFR) allows precise measurement of blood flow in the arteries to the heart, and is more reliable than pictures alone to determine…
- Conditions
- Acute Myocardial Infarction, STEMI, Coronary Artery Disease, Atherosclerotic Plaque Disruption With Thrombosis of Artery
- Trial name
- MIAMI (NCT02926755)
- Testing
- Coronary Angiography
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Corewell Health East
Branch Retinal Vein Occlusion
Comparison of Intravitreal Ranibizumab and Macular Laser Photocoagulation for ME Following Branch Retinal Vein Occlusion (BRVO)
This study is designed to evaluate the efficacy of intravitreal Ranibizumab in comparison with macular laser photocoagulation as treatments for macular edema secondary to branch retinal vein occlusion.
- Trial name
- NCT01189526
- Testing
- Ranibizumab, macular laser photocoagulation
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul Retina Investigator Group
Venous Thromboembolism, Deep Vein Thrombosis
A Study of Dabigatran Etexilate as Primary Treatment of Malignancy Associated Venous Thromboembolism
This trial aims at determining if dabigatran is effective in the treatment of malignancy associated VTE. Tolerance and safety of dabigatran will also be assessed.
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Pulmonary Embolism
- Trial name
- NCT03240120
- Testing
- Dabigatran etexilate, Tinzaparin
- Where
- Hong Kong
- Volunteers
- 99 people
- Sponsor
- The University of Hong Kong
Venous Thromboembolism
Dabigatran Etexilate Compared With Enoxaparin in Prevention of Venous Thromboembolism (VTE) Following Total Hip Arthroplasty
The primary objective of the trial is to demonstrate non-inferiority of 220 mg oral dabigatran etexilate compared to 40 mg subcutaneous enoxaparin administered once daily.
- Trial name
- NCT00657150
- Testing
- Enoxaparin, Dabigatran etexilate
- Where
- 108 sites in United States, Australia and 17 more
- Volunteers
- 2,055 people
- Sponsor
- Boehringer Ingelheim
Patients Hospitalized for More Than 48 Hours, Acute Medical Illness
Incidence and Risk Factors of Venous Thrombosis of the Lower Limbs After Hospitalization in Medical Patients at Risk
In Tunisia, the available data are limited regarding the incidence of venous thrombosis of the lower limbs (TVMI) post-hospitalization, whether symptomatic or subclinical.
- Trial name
- MTE (NCT05512923)
- Where
- Tunisia
- Volunteers
- 2,000 people
- Sponsor
- University of Monastir
Central Retinal Vein Occlusion
601 Versus Ranibizumab in Patients With Central Retinal Vein Occlusion (CRVO)
To evaluate the safety and efficacy of intravitreal recombinant humanized anti-VEGF monoclonal antibody in patients with visual impairment due to macular edema secondary to CRVO
- Trial name
- NCT04667910
- Testing
- 601 1.25mg, Ranibizuman 0.5 mg
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.
Women's Health, Blood Coagulation Disorders
The Effect of the Mini-pill on Blood Factors in Women at Increased Risk for Forming Blood Clots
We propose a prospective cohort study to assess the effect of the progesterone only contraceptive pill (minipill) on coagulation parameters known to be associated with risk of thrombosis (blood clots) in women who are at…
- Trial name
- NCT00580424
- Testing
- Norethindrone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Vermont
Deep Vein Thrombosis
Comparison Of Percutaneous Mechanical Thrombectomy With Different Access in Treatment of Acute Deep Venous Thrombosis
The study aims to compare the modified approach through ipsilateral deep calf venous access or contralateral femoral venous access with the traditional approach through ipsilateral popliteal venous access for iliofemoral deep…
- Trial name
- NCT06124768
- Testing
- Percutaneous mechanical thrombectomy (PMT) by the modified approach, Percutaneous mechanical thrombectomy (PMT) by the traditional approach, Traditional approach
- Where
- China
- Volunteers
- 210 people
- Sponsor
- RenJi Hospital
Central Retinal Vein Occlusion
Lucentis for Central Retinal Vein Occlusion (CRVO)
The purpose of this study is to determine whether ranibizumab will be effective in reducing if not eliminating the macular edema associated with the disease, central retinal vein occlusion (CRVO).
- Trial name
- NCT00406796
- Testing
- Ranibizumab
- Where
- 4 sites in United States
- Volunteers
- 20 people
- Sponsor
- California Retina Consultants
Systemic Inflammatory Markers, Portal Vein Thrombosis
A Practical Nomogram Based on Systemic Inflammatory Markers for Predicting Portal Vein Thrombosis in Patients With Liver Cirrhosis
Immunothrombosis has recently been used to describe the responses/mechanisms in thrombosis. Systemic inflammatory markers are prognostic markers for a variety of thrombotic conditions; however, their potential value in predicting…
- Trial name
- NCT05541562
- Testing
- clinical laboratory tests, and imaging characteristics
- Where
- China
- Volunteers
- 478 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Venous Thromboembolism, Deep Vein Thrombosis
SToP: Venous Thromboembolism Screening in the Trauma Population
This is a prospective, randomized vanguard trial of trauma patients admitted to the trauma surgery service at Intermountain Medical Center who are deemed to be at high risk for venous thromboembolism.
- Conditions
- Venous Thromboembolism, Deep Vein Thrombosis, Trauma, Multiple
- Trial name
- SToP (NCT02978950)
- Testing
- Duplex ultrasound surveillance, No ultrasound surveillance
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Intermountain Health Care, Inc.
Deep Venous Thrombosis
Pneumatic Compression for Preventing Venous Thromboembolism
Patients admitted to the intensive care unit are at high risk of developing clots in the veins of the lower extremities. The objective of this study is to examine whether the use of a device that provides intermittent compression…
- Trial name
- PREVENT (NCT02040103)
- Testing
- pneumatic compression
- Where
- Saudi Arabia
- Volunteers
- 2,000 people
- Sponsor
- King Abdullah International Medical Research Center
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