Clinical trials: Thyroid Disorders
Hypopituitarism
Central Hypothyroidism and Cardiovascular Risk
Retrospective trial of 300 patients with pituitary insufficiency treated in Department of Medica Endocrinology, Rigshospitalet, Copenhagen University concerning levothyroxine (T4) replacement and cardiovascular risk factors.
- Trial name
- NCT01574859
- Testing
- levothyroxine
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Graves Disease (Basedow's Disease)
Rubus Sanctus (Wild Blackberry) Root Extract as a Dietary Supplement for Graves' Disease
The aim of this single-blind, randomized, experimental study was to investigate the effect of Rubus sanctus root extract, which has antioxidant properties, added to the routine diet of patients with Graves' disease on the…
- Trial name
- RCT (NCT07164079)
- Testing
- blackberry root, black tea
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people
- Sponsor
- Betul Uner
Preoperative Anxiety, Fear and Anxiety
Nurse-Led Emotional Freedom Technique for Preoperative Anxiety and Fear in Thyroid Surgery
Emotional Freedom Technique (EFT) is a non-invasive, low-cost complementary intervention that has been used in various clinical settings to reduce anxiety and psychological distress.
- Conditions
- Preoperative Anxiety, Fear and Anxiety, Thyroid Surgery
- Trial name
- EFT (NCT07454044)
- Testing
- Emotional Freedom Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Saglik Bilimleri Universitesi
Breast Cancer, Colo-rectal Cancer
The French E3N Prospective Cohort Study
The French E3N cohort was initiated in 1990 to investigate the risk factors associated with cancer and other major non-communicable diseases in women.
- Conditions
- Breast Cancer, Colo-rectal Cancer, Parkinson Disease, Asthma
- Trial name
- E3N (NCT03285230)
- Where
- France
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Alopecia Areata, Alopecia Totalis
The Epidemiology, Management and Comorbidities in Alopecia Areata in Czech Republic
The study series consists of three studies with the aim to assess the incidence, prevalence, risk factors, comorbidities and management of patients with alopecia areata in Czech Republic based on the patients and registry of a…
- Conditions
- Alopecia Areata, Alopecia Totalis, Alopecia Universalis, Alopecia Areata (& Ophiasis)
- Trial name
- NCT05098600
- Testing
- Exposure of interest
- Where
- Czechia
- Volunteers
- 123 people
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Epilepsy, Child, Only
The Effect of Levetiracetam on Lipid Profile in Children
Levetiracetam is a widely prescribed antiseizure medication in epileptic children due to an estimated better safety profile and easy accessibility.
- Conditions
- Epilepsy, Child, Only, Thyroid, Lipid Disorder
- Trial name
- NCT05276271
- Testing
- the blood sample test results
- Where
- Turkey (Türkiye)
- Volunteers
- 91 people
- Sponsor
- Ege University
Iodine Disorders
Exploration of Effects of Excessive Iodine on Children and Tolerable Upper Intake Level of Iodine for Children
With the implementation of Universal Salt Iodization (USI) in 1995, China has successfully combated Iodine Deficiency Diseases (IDD).
- Trial name
- NCT02915536
- Testing
- Natural exposure of high iodine
- Volunteers
- 2,229 people
- Sponsor
- Wanqi Zhang
Metabolic Syndrome
Evaluation of the Pattern of Thyroid Dysfunctions in Patients With Metabolic Syndrome
The study on evaluation the pattern of TD in MetS population may help us to know the magnitude of overlap of these two disease entities and may highlight the importance of thyroid function tests in patients with MetS.
- Trial name
- NCT03214068
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Assiut University
Thyroid Eye Disease
The Effect of a New Antioxidant Combination (ASTED) on Moderate to Severe Thyroid Eye Disease
ASTED (Antioxidant Supplements for TED) trial is an investigator-initiated, randomized, triple masked, clinical trial of a selected combination of vitamins and minerals versus placebo in patients with moderate to severe thyroid…
- Trial name
- NCT02422368
- Testing
- Methylprednisolone + ASTED
- Where
- 2 sites in Iran
- Sponsor
- Iran University of Medical Sciences
Metastatic Medullary Thyroid Cancer
CAPRELSA® REGISTRY: a Belgian Registry to Evaluate the Use of Vandetanib (Caprelsa®) in Current Clinical Practice
In this registry it is planned to include all Belgian patients diagnosed with aggressive and symptomatic unresectable locally advanced or metastatic Medullary Thyroid Cancer (MTC) who have been prescribed Caprelsa® (vandetanib).
- Trial name
- CaprelsaReg (NCT02109250)
- Testing
- Caprelsa
- Where
- 8 sites in Belgium
- Volunteers
- 10 people
- Sponsor
- Genzyme, a Sanofi Company
Medullary Thyroid Carcinoma
A Study of HA121-28 Tablets in Patients With Medullary Thyroid Carcinoma (MTC)
This is a single-arm, open-label, multicenter study designed to evaluate the preliminary antineoplastic activity, safety and tolerability of HA121-28 tablets administered orally in patients with medullary thyroid cancer (MTC).
- Trial name
- NCT04787328
- Testing
- HA121-28 tablets
- Where
- 13 sites in China
- Volunteers
- 30 people
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Differentiated Thyroid Cancer
Primary Care Transfer for Thyroid Cancer Patients
Introduction: Differentiated thyroid cancer (DTC) is the most common endocrine malignancy. It presents low recurrence rates (2-5%) and the consensus of DTC recommends long-term follow-up, without a definition of maximum follow-up…
- Trial name
- NCT03794375
- Testing
- Telehealth, Usual care
- Where
- Brazil
- Volunteers
- 206 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Pregnancy
Thyroid Dysfunction and Obstetric Complications
Obstetric complications are common and can be responsible for maternal and foetal morbidity and mortality. Thyroid dysfunction has been identified as a possible cause of obstetric complications.
- Trial name
- TDOC (NCT02815501)
- Testing
- blood samples
- Where
- France
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Differentiated Thyroid Cancer, Thyroid Cancer
Thyroid Hormone Replacement After Radio Iodine: Value and Efficacy
This study will be a multicentre prospective cohort study on TH-substitution after thyroid hormone withdrawal preceding radioiodine treatment.
- Conditions
- Differentiated Thyroid Cancer, Thyroid Cancer, Levothyroxine, Liothyronine
- Trial name
- THRIVE (NCT06647602)
- Testing
- Euthyrox (levothyroxine), Cytomel (liothyronine)
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- University Medical Center Groningen
Endometrioma, Thyroid
Comparison of Thyroid Volumes in Patients With and Without Endometrioma
The aim of our study is to evaluate whether there is a statistical difference between thyroid gland volume in patients with pathological diagnosis of endometriosis or endometrioma and in patients who underwent surgery for other…
- Trial name
- NCT05323539
- Testing
- Evaluating Thyroid Volumes by ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Adana City Training and Research Hospital
Thyroid Associated Ophthalmopathy
Orbital Radiotherapy in Grave's Ophthalmopathy 1 Week vs 2 Weeks (OraGO-1 Trial)
Thyroid ophthalmopathy, also known as thyroid eye disease or Graves' ophthalmopathy, is a condition characterized by inflammation and swelling of the tissues around the eyes, often accompanied by protrusion of the eyeballs.
- Trial name
- NCT06392906
- Testing
- Short course radiation therapy, Standard course radiation therapy
- Where
- Thailand
- Volunteers
- 68 people
- Sponsor
- Janjira Petsuksiri
Thyroid, Reference Values
Gestational Age Specific Thyroid Function Reference Range
It has been well accepted that maternal thyroid dysfunction has adverse affects on both mothers and fetuses. However, the dramatical changes during pregnancy make the interpretation of thyroid function test (TFT, i.e.
- Conditions
- Thyroid, Reference Values, Pregnancy
- Trial name
- NCT03663517
- Volunteers
- 599 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Differentiated Thyroid Cancer
Surufatinib as Neoadjuvant Treatment for Locally Advanced or Metastatic Differentiated Thyroid Cancer
Locally advanced thyroid cancer has a wide range of surgery, large trauma and high local recurrence rate. It is one of the main causes of death in patients with thyroid cancer.
- Trial name
- NCT05989425
- Testing
- surufatinib
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Fudan University
Locally Advanced Larynx, Hypopharyngeal Squamous Cell Cancers, Locally Advanced Thyroid Cancers
A Phase I/II Study of the Use of Intensity Modulated Radiotherapy (IMRT) in Cancer of the Thyroid, Larynx and Hypopharynx
This study is a phase I/II dose escalation trial designed to test the feasibility of delivering IMRT to thyroid, larynx and hypopharynx cancer patients, and to assess the safety and possible improvement in outcome when the dose…
- Trial name
- NCT02055989
- Testing
- Dose-escalated radiotherapy level 1, Sequential dose-escalated radiotherapy level 2
- Where
- United Kingdom
- Volunteers
- 105 people
- Sponsor
- Royal Marsden NHS Foundation Trust
Thyroid Nodule
FNA Guided Ultrasonography Needle Technique Axial Vs Lateral Approach Study
Ultrasound-guided fine needle aspiration cytology (FNAC) has been proven to be an accurate and efficient tool in thyroid nodule evaluation.
- Trial name
- NCT04458233
- Testing
- long axis FNA method
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Ziv Hospital
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