Clinical trials: Thyroid Function
Pregnancy, Thyroid Function Tests
Maternal Thyroid Function in Early Pregnancy and Their Relationship With Gestational Diabetes Mellitus
This study was conducted to analyze the role of TSH level and TPOAb status in early pregnancy and use this information in assessment of the risk of gestational diabetes mellitus at different weeks of gestation when the FT4 level…
- Conditions
- Pregnancy, Thyroid Function Tests, Gestational Diabetes Mellitus
- Trial name
- NCT02555332
- Testing
- 75g oral glucose tolerance test (OGTT)
- Volunteers
- 7,729 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Klinefelter Syndrome, Thyroiditis, Autoimmune
Thyroid Function and Structure in Klinefelter Syndrome
This is a longitudinal retrospective study for the evaluation of thyroid function and structure in patients with Klinefelter syndrome compared to healthy controls and patients affected by chronic lymphocytic thyroiditis.
- Conditions
- Klinefelter Syndrome, Thyroiditis, Autoimmune, Hypothyroidism
- Trial name
- THINKS (NCT05581147)
- Where
- Italy
- Volunteers
- 600 people
- Sponsor
- University of Roma La Sapienza
Value of Thyroid Functions in Children With Congenital Heart Diseases
Thyroid Functions in Children With Congenital Heart Diseases
Thyroid hormone is critical for normal neurocognitive development in young infants, and even transient hypothyroidism can cause adverse neurodevelopmental outcomes.
- Trial name
- NCT05103774
- Testing
- T3-T4-TSH
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hypothyroidism, CHD
Hypothyroidism With Congenital Heart Disease (CHD)
Congenital hypothyroidism is one of the most preventable causes of neurocognitive impairment because early treatment is possible in neonates. The thyroid hormone is important for normal growth and development in infancy.
- Trial name
- NCT03496363
- Testing
- TSH , T4
- Volunteers
- 50 people
- Sponsor
- Assiut University
Thyroid Dysfunction, Atherosclerosis
The TRUST Trial - CardioVascular Imaging ECHO
Coronary heart disease (CHD) and heart failure (HF) are the leading causes of mortality and morbidity, particularly with the current context of an aging population.
- Conditions
- Thyroid Dysfunction, Atherosclerosis, Heart Failure
- Trial name
- NCT02832960
- Testing
- Levothyroxine
- Where
- 3 sites in Switzerland
- Volunteers
- 185 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Thyroid Surgery, Parathyroid Dysfunction
PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial.
The goal of this randomized clinical trial is to learn if there are any added benefits of using near-infrared autofluorescence (NIRAF) probe-based imaging system (the PTeye) for intraoperative identification of parathyroid glands…
- Conditions
- Thyroid Surgery, Parathyroid Dysfunction, Hypoparathyroidism Post-surgical
- Trial name
- PTSURGEYE (NCT06765941)
- Testing
- Probe-based near-infrared parathyroid autofluorescence detection system, Surgeons naked eyes for parathyroid glands identification
- Where
- Poland
- Volunteers
- 154 people
- Sponsor
- Marcin Barczynski
Thyroid, HIV Infections
Prevalence of Thyroid Function Abnormalities in HIV-infected Patients
Review the evolution of thyroid function in HIV-infected patients, with sufficient follow-up.
- Trial name
- THYVI (NCT03149354)
- Testing
- Assay of TSH, FT3 and FT4 by immuno-radiometric method
- Where
- France
- Volunteers
- 154 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Thyroid, Genetic Predisposition to Disease
PheWAS of a Polygenic Predictor of Thyroid Function
Performing a phenome-wide association study (PheWAS) identifying clinical diagnoses associated with a polygenic predictor of Thyroid stimulating hormone (TSH) levels identified by a previously published genome-wide association…
- Trial name
- PHETHYR (NCT03597659)
- Testing
- phenome-wide association study (PheWAS)
- Where
- France
- Volunteers
- 37,154 people, healthy volunteers welcome
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Contraception
Effects on Hemostasis, Lipids, Carbohydrate Metabolism, Adrenal & Thyroid Function of the Combined Oral Contraceptive NOMAC-E2 Compared to a COC Containing LNG-EE (292004)(COMPLETED)(P05764)
The primary purpose of this study is to evaluate the effects of the combined oral contraceptive (COC) NOMAC-E2 on hemostasis, lipids, carbohydrate metabolism, adrenal function, and thyroid function.
- Trial name
- NCT00511355
- Testing
- NOMAC-E2, Levonorgestrel and Ethinyl Estradiol
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Organon and Co
Thyroid Function, Iodine Nutrition Status
Longitudinal Study on the Influence of Iodine Nutrition Status on Thyroid Function of Childbearing Age Women During Pregnancy and 6 Weeks Postpartum
The goal of this observational study is to provide a reference for formulating individual appropriate iodine intake programs for women during pregnancy and postpartum and improving the monitoring and evaluation system of maternal…
- Trial name
- NCT05677581
- Testing
- iodine nutrition status
- Where
- China
- Volunteers
- 2,100 people, healthy volunteers welcome
- Sponsor
- Beijing Friendship Hospital
Iodine Deficiency, Infant Development
Maternal Iodine Supplementation and Effects on Thyroid Function and Child Development
Rationale: In regions of severe endemic goiter, the adverse effects of in utero iodine deficiency on neuromotor development are well established: randomized controlled trials of iodine supplements given to iodine deficient…
- Trial name
- MITCH (NCT00791466)
- Testing
- Iodine
- Where
- 2 sites in India, Thailand
- Volunteers
- 829 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Thyroid Dysfunction, Hypothyroidism
Fetal and Neonatal Thyroid in Pregnancies With Severe Acute Respiratory Syndrome Coronavirus 2 ( SARS- COV2 ) COVID-19
The thyroid gland has been shown to be a common target for COVID 19 virus. Babies born to mothers positive for COVID 19 infections were noticed to have elevated thyroid stimulating hormone ( TSH ) levels on screening.
- Conditions
- Thyroid Dysfunction, Hypothyroidism, Hyperthyroidism
- Trial name
- COVID-19 (NCT05385029)
- Testing
- Thyroxine
- Where
- Saudi Arabia
- Volunteers
- 95 people
- Sponsor
- OMER B ABDELBASIT
Pregnancy
HAPPY Study: Holistic Approach to Pregnancy and the First Postpartum Year
The HAPPY study is a large prospective longitudinal cohort study in which pregnant women (N≈2,500) are followed during the entire pregnancy and the whole first year postpartum.
- Trial name
- HAPPY (NCT05364346)
- Volunteers
- 2,269 people
- Sponsor
- Tilburg University
Vitamin D, Thyroid Autoimmune Disease
Vitamin D, Hashimato's Thyroiditis and Thyroid Functions
The goal of this retrospective observational study is to determine whether vitamin D levels differ in patients with Hashimoto's thyroiditis (HT) compared to those without Hashimoto's thyroiditis.
- Trial name
- NCT06726967
- Testing
- vitamin D 25(OH)D
- Where
- Turkey (Türkiye)
- Volunteers
- 81,180 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University
Hashimoto Disease, Pregnancy Related
Management of Thyroid Function in Hashimoto's Thyroiditis During Pregnancy
The management of thyroid function in pregnancy has been object of several guidelines in the last years. Normal thyroid function reduces prenatal and post-natal risks and gestational complaints.
- Conditions
- Hashimoto Disease, Pregnancy Related, Thyroid Dysfunction
- Trial name
- NCT04613323
- Volunteers
- 100 people
- Sponsor
- Centro Diagnostico Priamar
Breast Cancer, Fatigue
Thyroid Dysfunction in Women With Newly Diagnosed Breast Cancer Compared to Healthy Volunteers
RATIONALE: Learning about thyroid dysfunction in patients with breast cancer may help plan treatment and may help patients live more comfortably.
- Conditions
- Breast Cancer, Fatigue, Hypothyroidism
- Trial name
- NCT00336102
- Testing
- physiologic testing, fatigue assessment and management, management of therapy complications
- Where
- 41 sites in United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Iodine Deficiency, Nutrition Poor
Effects of Maternal Multiple Micronutrient Supplementation During Lactation on Child Development in Ethiopia
The goal of this clinical trial is to learn about the effects of iodine-containing multiple micronutrient supplements provided to breastfeeding mothers who live in settings with mild iodine deficiency.
- Conditions
- Iodine Deficiency, Nutrition Poor, Development, Infant, Breastfeeding
- Trial name
- EMECHAT (NCT05901766)
- Testing
- UNIMMAP Multiple Micronutrient Supplement
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Brown University
Thyroid Cancer, Hypoparathyroidism
Study on Application of Suturing Parathyroid Markers in Thyroid Cancer Surgery
To study the protective effect of suture parathyroid marker method on the function of parathyroid gland in thyroid cancer surgery
- Conditions
- Thyroid Cancer, Hypoparathyroidism, Marker; Structural, Complication of Surgical Procedure
- Trial name
- NCT03514251
- Testing
- The suture marks the location of the parathyroid gland
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Bo Wang,MD
Leukaemia (Chronic)
What is the Impact of TKI on Thyroid Function in CML Patients?
Evaluation of the impact of various TKI on thyroid function in patients diagnosed with cml
- Trial name
- NCT07200882
- Volunteers
- 76 people
- Sponsor
- Assiut University
Diabetes, Thyroid Disease
Thyroid Function and Diabetes Complications
The purpose of this study is to investigate the potential association between thyroid function and diabetes complications in the elderly subjects with type 2 diabetes mellitus (T2DM).
- Trial name
- NCT03001336
- Testing
- no intervention
- Volunteers
- 260 people
- Sponsor
- Nanjing First Hospital, Nanjing Medical University