Clinical trials: Thyroid Gland Nodule
Thyroid Nodule, Thyroid Dysfunction
Postoperative Hypocalcemia After Thyroidectomy
This retrospective cohort study investigates predictors of postoperative hypocalcemia following thyroidectomy procedures at Minia University Hospital over a 10-year period (2014-2024).
- Conditions
- Thyroid Nodule, Thyroid Dysfunction, Hypocalcemia, Thyroid Cancer
- Trial name
- NCT07428057
- Where
- Egypt
- Volunteers
- 600 people
- Sponsor
- Minia University
Benign Thyroid Nodule, Quality of Life
Alterations in Quality of Life After Thyroidectomy for Benign Thyroid Disease
To detect any changes in Quality of Life in patients with benign thyroid diseases who undergo thyroidectomy compared to patients with benign thyroid diseases and conservative treatment and healthy subjects.
- Trial name
- NCT03566537
- Testing
- Thyroidectomy
- Where
- Greece
- Volunteers
- 73 people
- Sponsor
- Aristotle University Of Thessaloniki
Benign Thyroid Nodules
Thermal Ablation Vs Thyroidectomy for Large Benign Thyroid Nodules
To compare the safety, efficacy and quality of life between staged thermal ablation and thyroidectomy in the treatment of Large benign thyroid nodules.
- Trial name
- NCT06607133
- Testing
- surgery, staged thermal ablation
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Ming-an Yu
Cancer, Thyroid
Use of an In Vivo Optical Probe to Discriminate Benign From Malignant Thyroid Nodules
This study will investigate the usefulness of an optical probe in the differentiation of thyroid cancer from normal thyroid tissue in a thyroidectomy specimen.
- Trial name
- NCT01401855
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Thyroid Nodule
Percutaneous Radiofrequency Thermal Ablation in Compressive Thyroid Nodules
Percutaneous radiofrequency thermal ablation (RTA) was reported as an effective tool for the management of thyroid nodules (TNs).
- Trial name
- NCT01649206
- Testing
- Percutaneous Radiofrequency Thermal Ablation
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- Federico II University
Thyroid Neoplasms, Goiter, Nodular
Study of the Efficacy of Local Analgesia as an Adjunct to General Anesthesia in Thyroidectomy and Parathyroidectomy
We aim to study the effect of local anesthetic when used in conjunction with general anesthesia during thyroidectomy or parathyroidectomy.
- Conditions
- Thyroid Neoplasms, Goiter, Nodular, Thyroid Nodule, Graves' Disease
- Trial name
- NCT02205801
- Testing
- Superficial Cervical Plexus Block, Local Wound Infiltration, 0.9% saline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Chicago
Thyroid Neoplasms, Thyroid Nodule
Effect of Three Different Peak Airway Pressures on Determining Intraoperative Bleeding in Thryroidectomies
Patients undergoing thyroidectomy will be divided into three groups (30 cm H2O Group I, 40 cm H2O Group II, 50 cmH2O Group III).
- Trial name
- NCT03547648
- Testing
- peak airway pressure
- Where
- Turkey (Türkiye)
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Hyperthyroidism; Goiter, Multinodular Goiter
Pressure-enabled Retrograde Occlusive Therapy With Embolization for Control of Thyroid Disease (PROTECT Registry): A Multicenter Registry
Multi-center registry study to evaluate disease-related quality of life outcomes of thyroid embolization via pressure-enabled delivery (PED-TAE).
- Conditions
- Hyperthyroidism; Goiter, Multinodular Goiter, Thyroid Nodules, Thyroid Disease
- Trial name
- NCT06868459
- Testing
- Data Collection
- Where
- 4 sites in United States
- Volunteers
- 100 people
- Sponsor
- Sarasota Memorial Health Care System
Thyroid Nodule, Thyroid Neoplasms
TRAIL Study: Feasibility and Pilot
This is a pilot study to compare two ways of managing newly identified thyroid nodules that are likely to be cancerous based on ultrasound result and which under usual care would undergo immediate biopsy.
- Conditions
- Thyroid Nodule, Thyroid Neoplasms, Thyroid Cancer
- Trial name
- NCT06220656
- Testing
- Biopsy, Active Monitoring
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Thyroid Nodule
Radiofrequency Ablation Study in LatinX Patients
Benign thyroid nodules can still create cosmetic, compressive, or hormonal issues for patients. In the past, surgery was typically used to treat thyroid nodules causing the above issues through partial or complete thyroidectomy.
- Trial name
- NCT05903196
- Testing
- Mygen V-1000 RF system
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Northwell Health
Thyroid Nodule, Thyroid Neoplasms
FDG-PET/CT in Evaluation of Cytological Indeterminate Thyroid Nodules to Prevent Unnecessary Surgery (EfFECTS)
The purpose of this study is to determine whether the use of molecular imaging using FDG-PET/CT could prevent unnecessary diagnostic thyroid surgery in case of indeterminate cytology during fine-needle aspiration biopsy.
- Trial name
- EfFECTS (NCT02208544)
- Testing
- Diagnostic Thyroid Surgery, Ultrasound of the head and neck, FDG-PET/CT
- Where
- 15 sites in Netherlands
- Volunteers
- 132 people
- Sponsor
- Radboud University Medical Center
Feasibility Study for Thyroid Indication
"Clinical Evaluation of Opto-Acoustic Tomography for Detection and Diagnostic Differentiation of Thyroid Nodules"
Thyroid Feasibility Study
- Trial name
- NCT03032198
- Testing
- Imagio OA/US
- Where
- 2 sites in United States
- Volunteers
- 37 people
- Sponsor
- Seno Medical Instruments Inc.
Thyroid, Thyroid Nodule
Comparison of TOETVA and Conventional Thyroidectomy
Introduction-Objective: The application of transoral endoscopic thyroidectomy vestibular approach (TOETVA) is gradually increasing recently.
- Conditions
- Thyroid, Thyroid Nodule, Surgery
- Trial name
- TOETVA (NCT04647006)
- Testing
- thyroid
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- MUnlu
Thyroid Nodule
Clinical Diagnostic Approach for Cases of Thyroid Nodules
Thyroid nodules are a common presentation in the clinic, with an increasing incidence, especially in women. Their clinical significance is mainly related to excluding malignancy (4.0 to 6.5% of all thyroid nodules).
- Trial name
- NCT03884140
- Volunteers
- 1 people
- Sponsor
- Assiut University
Thyroid Nodule
Comparison of Anesthesia Effects of Sevoflurane and Propofol Combined With Dexmedetomidine in Intraoperative Neuromonitoring During Thyroidectomy
According to the previous studies, it is reported that the use of sevoflurane in the maintenance of anesthesia may lead to delayed occurrence of positive electromyographic (EMG) signal and lower obtained signal amplitude.
- Trial name
- NCT04680650
- Testing
- Anesthesia was maintained with sevoflurane, Anesthesia was maintained with propofol
- Where
- China
- Volunteers
- 66 people
- Sponsor
- Affiliated Cancer Hospital & Institute of Guangzhou Medical University
Benign Thyroid Nodules, Ablation
Microwave vs. Radiofrequency Ablation for Benign Thyroid Nodules: A Multicenter Randomized Controlled Trial Study
Compared with traditional treatment methods, ultrasound-guided thermal ablation is more targeted, less invasive and more reliable.
- Trial name
- NCT04046354
- Testing
- Ultrasound-guided Percutaneous Microwave Ablation, Ultrasound-guided Percutaneous Radiofrequency Ablation
- Where
- China
- Volunteers
- 149 people
- Sponsor
- Chinese PLA General Hospital
Thyroid Nodule
Ultrasound-guided Thermal Ablation for Bethesda III/IV Thyroid Nodules
To evaluate the long-term outcomes of ultrasound-guided thermal ablation for Bethesda III/IV thyroid nodules
- Trial name
- NCT06733753
- Testing
- ultrasound-guided thermal ablation
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Chinese PLA General Hospital
Thyroid Nodule
Minimal Invasiveness of Endoscopic Thyroidectomy
The investigators had performed more than 250 cases of breast approach endoscopic thyroidectomy (BAET). The goal of this study is to evaluate whether BAET could be a minimally invasive procedure under the expert's hands.
- Trial name
- NCT00877630
- Where
- China
- Sponsor
- Second Military Medical University
Thyroid Nodule
RFA (Radiofrequency Ablation) Versus EA (Ethanol Ablation) for Predominantly Cystic Thyroid Nodules
Ultrasound-guided ethanol ablation is an effective treatment modality for patients with cystic thyroid nodules (cystic portion > 90%); however it is less effective in predominantly cystic thyroid nodules (90% > cystic portions >…
- Trial name
- NCT01778400
- Testing
- radiofrequency ablation, Ethanol ablation
- Where
- South Korea
- Volunteers
- 50 people
- Sponsor
- Asan Medical Center
Thyroid Nodule, Thyroid Goiter
Prospective Evaluation of the Pulse Biosciences nPulse™ Vybrance™ Percutaneous Electrode System
The primary objective of this study is to reproduce in a multi-center study results obtained during the feasibility First-In-Human (FIH) study with Prof.
- Conditions
- Thyroid Nodule, Thyroid Goiter, Ablation
- Trial name
- PRECISE-BTN (NCT07287176)
- Testing
- nPulse Vybrance Percutaneous Electrode System
- Where
- 3 sites in United States
- Volunteers
- 103 people
- Sponsor
- Pulse Biosciences, Inc.