Clinical trials: Thyroid Gland Nodule
Thyroid Nodules, Thyroid Nodule
Comparing a New 3D Technology Used to Measure Thyroid Nodule Volume to Standard Ultrasound
After thyroid ablation procedure, the volume of the thyroid nodule (s) needs to be measured to see how well the procedure worked. Currently, these volumes are measured using traditional 2D ultrasound imaging.
- Trial name
- NCT07178080
- Testing
- PIUR tUS Infinity Ultrasound
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Sarasota Memorial Health Care System
Thyroid Cancer
Assessment of Repeat Fine Needle Aspiration (FNA) to Detect Thyroid Cancer
Thyroid nodules are common (prevalence of 12.7% in women), but are malignant in only 5% of cases. International experts agree that a preliminary cytological examination by fine needle aspiration (FNA) is required.
- Trial name
- CYT2THYR (NCT00954837)
- Testing
- Fine needle aspiration
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thyroid Nodules
Characterization of Thyroid Nodules Using Contrast Enhanced Ultrasound
This study will evaluate thyroid nodules using specialized ultrasound imaging methods.
- Trial name
- NCT01225016
- Testing
- Definity contrast agent
- Where
- United States
- Sponsor
- University of Alabama at Birmingham
Thyroid Nodule
Elastography and FNAC in Thyroid Nodule
Evaluate the accuracy of USE in comparison with FNAC in characterization of solitary thyroid nodule and assessment the risk of malignancy
- Trial name
- NCT05734326
- Testing
- Ultrasound elastography
- Volunteers
- 50 people
- Sponsor
- Assiut University
Hurthle Cell Thyroid Cancer, Tall Cell Variant Thyroid Cancer
Studies on Tumors of the Thyroid
Participants in this study will be patients diagnosed with or suspected to have a thyroid nodule or thyroid cancer. The main purpose of this study is to further understand the methods for the diagnosis and treatment of thyroid…
- Conditions
- Hurthle Cell Thyroid Cancer, Tall Cell Variant Thyroid Cancer, Follicular Thyroid Cancer, Thyroid Cancer
- Trial name
- NCT00001160
- Testing
- 68-Gallium Dotatate
- Where
- United States
- Volunteers
- 2,500 people
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Thyroid Carcinoma, Thyroid Papillary Carcinoma
Malignancy Predictors, Bethesda and TI-RADS Scores Correlated With Final Histopathology in Thyroid Diseases
In the last decades, thyroid cancer incidence has continuously increased all over the world, almost exclusively due to a sharp rise in the incidence of the papillary histologic subtype, which has the highest incidence of…
- Conditions
- Thyroid Carcinoma, Thyroid Papillary Carcinoma, Multinodular Goiter, Adolescent, Solitary Thyroid Nodule
- Trial name
- NCT04411290
- Testing
- Total thyroidectomy (TT)
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Umraniye Education and Research Hospital
Thyroid Cancer, Active Surveillance
Patients With a Single, Small (2 cm or Less) Cancer Nodule in the Thyroid Gland Will be Offered Active Surveillance Initially for 5 Years. In Case of Cancer Growth or Changes in Ultrasonographic Appearance, Further Treatment Will be Offered.
Patients with a single, small (less than 2 cm) cancer nodule in the thyroid gland will be offered active surveillance initially for 5 years.
- Trial name
- NCT07822217
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- University of Aarhus
Pleuropulmonary Blastoma, Sertoli-Leydig Cell Tumor
International PPB/DICER1 Registry
PPB has strong genetic implications, with a unique set of conditions in an individual or their family, occurring mostly in childhood and adolescence.
- Conditions
- Pleuropulmonary Blastoma, Sertoli-Leydig Cell Tumor, DICER1 Syndrome, Cystic Nephroma
- Trial name
- NCT03382158
- Where
- United States
- Volunteers
- 3,400 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Thyroid Nodule
Protein Classifier for Thyroid Indeterminate Nodules
In multi-center, prospective, double-blind cohorts, PCT-DIA/MS protein classifier supported by artificial neural networks will be validated to classify thyroid indeterminate nodules.
- Trial name
- NCT04477798
- Testing
- PCT-DIA/MS
- Where
- China
- Volunteers
- 320 people
- Sponsor
- Luo Dingcun
PET / CT, FDG PET/CT
18F-FDG PET/TC in TIR3A e TIR3B
The primary objective of this study is to evaluate the diagnostic performance of 18F-FDG PET/CT performed by normal care pathway in the identification of malignancy of undetermined resulting thyroid lesions at cytology (TIR3A and…
- Conditions
- PET / CT, FDG PET/CT, Cytology, Thyroid Nodules
- Trial name
- PET-TIR3-2021 (NCT06829043)
- Testing
- clinical practice drug treatment
- Where
- Italy
- Volunteers
- 216 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Systemic Sclerosis, Hashimoto Thyroiditis
Sonographic and Laboratory Evaluation of the Thyroid Gland in Patients With Systemic Sclerosis
Systemic sclerosis (SSc) is a systemic disease that involves various organs such as the skin, kidneys, gastrointestinal tract and lungs.
- Conditions
- Systemic Sclerosis, Hashimoto Thyroiditis, Thyroid Nodules
- Trial name
- NCT01270425
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Meir Medical Center
Thyroid Cancer
Factors Influencing Inadequacy in Rapid Onsite Evaluation of Ultrasound Guided Fine Needle Aspiration (FNA) Samples of Thyroid Nodules
Thyroid nodules are a common clinical finding with a prevalence of around 50-67% in the general population using ultrasound examinations.
- Trial name
- FNA inadequacy (NCT06984991)
- Testing
- fine needle aspiration
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Assiut University
Thyroid Nodule
PACE4 in Thyroid Cancer
The investigation of thyroid nodules is limited by the fact that up to 49% of the fine needle aspirations (FNA) performed are of "indeterminate cytological signification".
- Trial name
- NCT03160482
- Testing
- Immunohistochemistry
- Where
- Canada
- Volunteers
- 39 people
- Sponsor
- Robert Day
Thyroid Nodule
Comparison of the Vocal Cord Imaging Techniques After Thyroidectomy
Recurrent nerve palsy is a complication of thyroidectomy. Most surgeons want to visualize the vocal cords after tyroidectomy. The aim is to compare the direct laringoscopy, videolaringoscopy, fiberoptic laringoscopy and…
- Trial name
- NCT02410928
- Testing
- direct laringoscopy, fiberoptic nasal laringoscopy, ultrasonograph
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Diskapi Teaching and Research Hospital
Thyroid Cancer
Molecular Markers in Thyroid Cancer
The purpose of this study is to evaluate how common gene mutations are in benign and malignant thyroid lesions.
- Trial name
- NCT00598364
- Where
- United States
- Volunteers
- 847 people
- Sponsor
- OHSU Knight Cancer Institute
Diabetes Mellitus, Hypothyroidism
Evaluation of the Effects of Teleconsultations on a Endocrinology Referral List
The aim of this study is evaluate the effects of telephone teleconsultations to primary care physicians (compared to the state's referral protocol) in the referrals waiting list for endocrinological appointments.
- Conditions
- Diabetes Mellitus, Hypothyroidism, Hyperthyroidism, Goiter
- Trial name
- NCT02710799
- Testing
- Teleconsultation, Protocol
- Where
- Brazil
- Volunteers
- 3,470 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Thyroid Nodule, Insulin Resistance
Insulin Resistance and Metformin Use on Volume of Benign Thyroid Nodules
It has been shown that insulin might be involved in the pathogenesis of thyroid growth. Objective To evaluate the impact of IR and metformin use on the volume of benign thyroid nodules (TNs).
- Trial name
- NCT03183752
- Testing
- Metformin
- Where
- Brazil
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Hospital Universitário Clementino Fraga Filho
Thyroid Nodule (Benign)
CellFX ® Percutaneous Electrode (PE) Treatment of Symptomatic Benign Thyroid Nodules
The objective of this clinical feasibility study is to evaluate initial clinical safety and device performance of the CellFX Percutaneous Electrode (PE) System for the treatment of symptomatic benign thyroid nodules.
- Trial name
- NCT06117085
- Testing
- CellFX® Percutaneous Electrode (PE) System
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Pulse Biosciences, Inc.
Thyroid Nodule, Goiter
Trial Comparing Complication Rates Associated With Robot-assisted Thyroidectomy to External Thyroidectomy
The main objective is to compare 12 month complication rates between a new surgical method for thyroidectomy (robot-assisted endoscopic thyroidectomy via a sub-clavical approach) and open thyroidectomy.
- Conditions
- Thyroid Nodule, Goiter, Thyroiditis, Graves Disease
- Trial name
- NCT01320813
- Testing
- Robot-assisted thyroidectomy, Open thyroidectomy
- Where
- France
- Volunteers
- 5 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Thyroid Cancer, Thyroid Nodule
Modified Cormack Lehane Scores Evaluated by Laryngoscopy During Awake Versus Under General Anesthesia
Nowadays, 5-step modified Cormack-Lehane scoring (MCL) system is frequently used in the observation of laryngeal structures by direct laryngoscopy.
- Conditions
- Thyroid Cancer, Thyroid Nodule, Thyroid Adenoma
- Trial name
- NCT03826680
- Testing
- Flexible fiberoptic laryngoscopy, Direct laryngoscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul University