Clinical trials: Thyroid Nodule (Diagnosis)
Thyroid Nodules
Thyroid Artery Embolization for the Treatment of Compressive Goiters.
Very few studies have investigated TAE as a treatment for goiter with compressive symptoms. What is the efficacy and safety of TAE for the treatment of compressive goiters in a population ineligible for or refusing standard…
- Trial name
- TAE (NCT07360587)
- Testing
- Thyroid Artery Embolization
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre de recherche du Centre hospitalier universitaire de Sherbrooke
Thyroid Cancer
Molecular Testing to Direct Extent of Initial Thyroid Surgery
The research study consists of the participant agreeing to 1) the use of preoperative molecular testing (ThyroSeq) to guide extent of initial surgery and 2) the prospective collection of medical record data related to treatment…
- Trial name
- NCT02947035
- Testing
- Thyroid lobectomy, Total thyroidectomy with CCND
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of Pittsburgh
Thyroid Nodules, Thyroid Nodule
Comparing a New 3D Technology Used to Measure Thyroid Nodule Volume to Standard Ultrasound
After thyroid ablation procedure, the volume of the thyroid nodule (s) needs to be measured to see how well the procedure worked. Currently, these volumes are measured using traditional 2D ultrasound imaging.
- Trial name
- NCT07178080
- Testing
- PIUR tUS Infinity Ultrasound
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Sarasota Memorial Health Care System
Thyroid Cancer, Thyroid Nodule
The Effect of Surgeon Emotional Support on Treatment Choice for Low-risk Thyroid Cancer
118 adults with benign thyroid nodules who were seen at a UW Health clinic for a fine needle biopsy and do not need surgery will be enrolled and can expect to be on study for a one-time visit of up to 60 minutes.
- Conditions
- Thyroid Cancer, Thyroid Nodule, Benign Thyroid Nodule
- Trial name
- NCT05132478
- Testing
- Emotionally Supportive Video, Standard Video
- Where
- United States
- Volunteers
- 126 people
- Sponsor
- University of Wisconsin, Madison
Autonomous Hyperfunctioning Thyroid Nodules
High Intensity Focused Ultrasound Device in Patients With Autonomous Hyperfunctioning Thyroid Nodules
The purpose of this study is to assess the efficacy and safety of High Intensity Focalized Ultrasound (HIFU) in the treatment for toxic Thyroids nodules
- Trial name
- NCT02169687
- Testing
- HIFU
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Theraclion
Thyroid Nodule, Follicular Neoplasm
Diagnostic Accuracy of Shear-Wave Elastography for the Preoperative Risk Stratification of Follicular Lesions of the Thyroid
As many as 70-85% subjects diagnosed with a follicular lesion on biopsy and undergoing surgery will have benign lesions verified by histopathology after surgery.
- Trial name
- NCT03106337
- Testing
- Shear-Wave Elastography
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Massachusetts General Hospital
Thyroid Nodule
The Diagnostic Value of Shear Wave Elastography
Background: The main goal when diagnosing thyroid nodules, is to differentiate the few malignant from the overwhelming background of benign nodules.
- Trial name
- NCT02150772
- Testing
- Shear Wave Elastography (SWE)
- Where
- Denmark
- Volunteers
- 308 people
- Sponsor
- University of Aarhus
Thyroid Nodule, Thyroid Cancer
Cognition and QoL After Thyroid Surgery
The development of cognitive dysfunction can profoundly affect HR-QoL as well as the possibility of societal participation and ability to work, and thereby relevantly impacts prospects for cancer survivorship.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Cognitive Decline, Survivorship
- Trial name
- NCT05088187
- Where
- Sweden
- Volunteers
- 320 people
- Sponsor
- Karolinska University Hospital
Thyroid Nodule
Decision Aid and Thyroid Nodules Management
Patients with small favorable malignant or indeterminate thyroid nodules will receive information about management of thyroid nodules.
- Trial name
- NCT05264857
- Testing
- Thyroid Nodule Management Education
- Where
- United States
- Volunteers
- 134 people
- Sponsor
- Stony Brook University
Blood Platelet Disorder, BRAF V600E
Preoperative Hemogram Parameters and BRAF Molecular Test Detected by Bethesda 3 Cytology.
The main hypothesis of this study is that preoperative hemogram parameters can be used as biomarkers for malignancy in patients with thyroid nodule Bethesda 3 cytology.
- Conditions
- Blood Platelet Disorder, BRAF V600E, Thyroid Nodule, Cytologic Atypia
- Trial name
- Bethesda3 (NCT06539702)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Thyroid Nodule, Thyroid Cancer
NGS-based Thyroscan Genomic Classifier in the Diagnosis of Thyroid Nodules
The purpose of this study is to evaluate the accuracy of Thyroscan in the differential diagnosis of benign and malignant thyroid nodules with suspecious ultrasound features
- Trial name
- NCT05025046
- Testing
- Thyroscan
- Where
- 4 sites in China
- Volunteers
- 250 people
- Sponsor
- Rigen Biotech
Thyroid Gland Nodule
Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules
This trial studies how well the diagnostic deoxyribonucleic acid (DNA) methylation signature works in detecting thyroid cancer in patients with thyroid nodules.
- Trial name
- NCT03676647
- Testing
- Diagnostic DNA Methylation Signature
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- City of Hope Medical Center
Thyroid Nodule
Effect of Ultrasound Guided Laser Ablation Therapy on Symptomatic Benign Thyroid Nodules
This is a prospective trial to evaluate the effects of laser ablation on symptomatic benign thyroid nodules. The study is designed to assess the clinical efficacy, safety, tolerability and impact on symptoms of single ultrasound…
- Trial name
- NCT04277455
- Testing
- Laser ablation of benign thyroid nodule
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johnson Thomas
Thyroid Neoplasms Benign, Thyroid Nodule
Red Blood Cell Distributions (RDW, RDW-CW) and Lymphocyte Monocyte Ratios (LMR) for the Malignant Thyroid Nodules
Thyroid surgery is the most common type of surgery among endocrine surgeries. This surgery is performed for patients with suspected malignancy, patients diagnosed with malignancy, and toxic nodular goiter.
- Conditions
- Thyroid Neoplasms Benign, Thyroid Nodule, Thyroid Cancer, Thyroid Diseases
- Trial name
- NCT06283368
- Testing
- Thyroidectomy, Bilaterally Total, Thyroidectomy, Unilaterally Total, Thyroidectomy, Complementary
- Volunteers
- 172 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Hypocalcemia, Hypoparathyroidism
NIRAF-Guided Parathyroid Identification During Thyroidectomy
This study evaluates whether a wearable near-infrared autofluorescence (NIRAF) imaging system can help surgeons identify and preserve parathyroid glands during thyroid surgery.
- Conditions
- Hypocalcemia, Hypoparathyroidism, Thyroid Diseases, Goiter, Nodular
- Trial name
- NCT07617584
- Testing
- Wearable Near-Infrared Autofluorescence Imaging System
- Where
- North Macedonia
- Volunteers
- 280 people
- Sponsor
- Ss. Cyril and Methodius University of Skopje
Thyroid Nodule
Percutaneous Laser Ablation in Benign Thyroid Nodules.Long Term Results
Thyroid nodule pathologies occur frequently and represent a clinical issue for the endocrinologists, surgeons, nuclear physicians as well as the general practitioners.
- Trial name
- NCT00858104
- Testing
- Percutaneous Laser Ablation
- Where
- 4 sites in Italy
- Volunteers
- 200 people
- Sponsor
- Elesta S.R.L.
Thyroid Nodule, Thyroid Cancer
HRQOL in Thyroid Cancer and Thyroid Tumours
Background: Most patients with thyroid cancer have a long life expectancy, and it has been assumed among health professionals that therefore the quality of life (QOL) is good.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Quality of Life
- Trial name
- NCT03676348
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Thyroid Nodule
Verbal Synchrony, Satisfaction and Decision-making in Face-to-face Consultations
Eligible participants will be: benign thyroid nodules patients, to be involved in a consultation with their endocrinologist and/or surgeon and/or radiologist, in order to discuss treatment options related to benign thyroid…
- Trial name
- NCT06342739
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- European Institute of Oncology
Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma
Radiofrequency Ablation for the Treatment of Benign or Low Risk Thyroid Nodule
This phase IV trial studies the effect of radiofrequency ablation in treating patients with benign or low risk thyroid nodule. Radiofrequency ablation uses a needle to deliver a high-frequency electric current to kill tumor cells…
- Conditions
- Benign Thyroid Gland Neoplasm, Recurrent Thyroid Gland Carcinoma, Thyroid Gland Follicular Tumor of Uncertain Malignant Potential, Thyroid Gland Nodule
- Trial name
- NCT05003856
- Testing
- Quality-of-Life Assessment, Radiofrequency Ablation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- M.D. Anderson Cancer Center
Osteoarthritis, Rheumatoid Arthritis
Reciprocating Medical Devices - a Study of a New Safety Device
The study design is a randomized study to directly compare the performance and the outcome of syringe and needle procedures with a standard syringe or the new reciprocating procedure device (RDP), which is a type of safety…
- Conditions
- Osteoarthritis, Rheumatoid Arthritis, Trauma, Thyroid Nodule
- Trial name
- RPD (NCT00651625)
- Testing
- Reciprocating Procedure Device (RPD) - AVANCA Re No. 1091001, conventional syringe - BD Ref 309604
- Where
- United States
- Volunteers
- 437 people
- Sponsor
- University of New Mexico