Clinical trials: Thyroid Nodules
Thyroid Nodule
Elastography and FNAC in Thyroid Nodule
Evaluate the accuracy of USE in comparison with FNAC in characterization of solitary thyroid nodule and assessment the risk of malignancy
- Trial name
- NCT05734326
- Testing
- Ultrasound elastography
- Volunteers
- 50 people
- Sponsor
- Assiut University
Thyroid Gland Carcinoma
Identification and Differentiation of Thyroid Nodules by Acoustic Imaging and Viscoelastic Parameters
This study is being done to identify and differentiate thyroid nodules by acoustic imaging and viscoelastic parameters.
- Trial name
- NCT06207188
- Testing
- Non-Interventional Study
- Where
- 3 sites in United States
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Thyroid Nodule
Levothyroxine Treatment in Thyroid Benign Nodular Goiter
We will study the effect of taking eltroxin at different time, i.e. fasting or postprandial periods. We will also study the effect of levothyroxin treatment in Chinese people
- Trial name
- NCT00552253
- Testing
- Levothyroxin treatment
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Thyroid Nodular Disease
Microvascular Profiling of Nodules in the Thyroid Gland
The purpose of this study is to examine tiny blood vessels in different thyroid nodules using advanced ultrasound. In the long term, we hope this can help doctors better tell the difference between types of nodules and more…
- Trial name
- NCT07041307
- Where
- 2 sites in Denmark
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Thyroid Nodule, Thyroid Cancer
Clinical Validation of a Molecular Signature to Detect Cancer in Thyroid Nodules With Indeterminate Cytology
1. Principal objective: The primary objective of this study is to validate the diagnostic performance of a Dx15 molecular test based on molecular transcriptomic signatures previously identified in distincts cohorts of samples to…
- Trial name
- CITHY (NCT02225509)
- Testing
- FNA biopsy for thyroid nodule(s)
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- Diaxonhit
Thyroid Nodule, Thyroid Carcinoma
CEUS Improves the Diagnostic Performance of SRSS of Thyroid Carcinoma
Contrast-enhanced ultrasound (CEUS) can sensitively show the blood perfusion characteristics of thyroid nodules, which is a useful supplement to gray-scale ultrasound.
- Trial name
- NCT06146764
- Testing
- Contrast-enhanced Ultrasound
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Thyroid Goiter, Thyroid Nodule
Analgesia for Thyroidectomy Using Bilateral Superficial Cervical Plexus Block With Bupivacaine Only or Adding Ketorolac to it.
Thyroidectomy is considered a common operation with moderate to severe postoperative pain in some patients. Patients are divided into two groups.
- Trial name
- NCT05180214
- Testing
- Bupivacain, Ketorolac
- Where
- Egypt
- Volunteers
- 46 people
- Sponsor
- Sohag University
Thyroid Nodule, Thyroid Cancer
Assessment the Cancer Risk of Indeterminate Thyroid Nodules Through Integration of Clinical, Ultrasonographic and Multiomic Features
Indeterminate thyroid nodules have a mild risk of malignancy (15-30%). The aim of our study is to individuate new biomarkers of thyroid carcinoma through multiomic analyses of blood samples and of specimen samples of patients…
- Trial name
- THYOMICS (NCT05428371)
- Testing
- Multiomic analyses of blood and surgical specimens
- Where
- Italy
- Volunteers
- 256 people
- Sponsor
- University of Cagliari
Cancer, Thyroid
Thyroid Ultrasound Elasticity (TrUE) Imaging
In this study the researchers will scan the thyroid nodules of patients scheduled for surgical removal of these nodules. During their preadmission testing, but prior to their surgery, the researchers will perform standard…
- Trial name
- NCT03307694
- Testing
- Ultrasound, Shear wave elasticity imaging, Multi-angle compound shear wave elasticity imaging
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Emory University
Thyroid Nodule
Ultrasound-guided Thermal Ablation for Bethesda III/IV Thyroid Nodules
To evaluate the long-term outcomes of ultrasound-guided thermal ablation for Bethesda III/IV thyroid nodules
- Trial name
- NCT06733753
- Testing
- ultrasound-guided thermal ablation
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Chinese PLA General Hospital
Thyroid Nodule, Thyroid Neoplasms
Khon Kaen University's Thyroidectomy Registry
The endoscopic thyroidectomy approach is gaining popularity in the surgical field. This registry tries to collect the outcomes including quality of life and complication for both endoscopic and conventional thyroidectomy methods.
- Conditions
- Thyroid Nodule, Thyroid Neoplasms, Thyroid Cancer
- Trial name
- NCT03031639
- Testing
- Endoscopic approach thyroidectomy
- Where
- Thailand
- Volunteers
- 98 people
- Sponsor
- Khon Kaen University
Ablation Techniques, RFA, Ablation Treatment
Efficacy and Safety of RFA vs MWA for Treatment of Large Benign Thyroid Nodules, RCT
We conduct a multi-institutional randomized control trial of RFA and MWA for the primary treatment of large, benign nodules. Adult patients >/=18 years of age who have a solitary thyroid nodule ≥20ml in volume who presents to 1)…
- Conditions
- Ablation Techniques, RFA, Ablation Treatment, Benign Thyroid Nodules, Local Anaesthesia
- Trial name
- NCT07804862
- Testing
- Radiofrequency ablation alone, Microwave ablation
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The University of Hong Kong
Thyroid Nodule, Thyroid Cancer
NGS-based Thyroscan Genomic Classifier in the Diagnosis of Thyroid Nodules
The purpose of this study is to evaluate the accuracy of Thyroscan in the differential diagnosis of benign and malignant thyroid nodules with suspecious ultrasound features
- Trial name
- NCT05025046
- Testing
- Thyroscan
- Where
- 4 sites in China
- Volunteers
- 250 people
- Sponsor
- Rigen Biotech
Fine Needle Aspiration Cytology, Thyroid Diseases
Accuracy of FNAC in Thyroid Nodules Compared to to Surgical Specimen : QOC Experience
Thyroid gland diseases are the second most common endocrine disease following diabetes mellitus(1). Thyroid nodules are common disorders with a prevalence ranged from 4 to 7% in adult population, 5%-30% are malignant…
- Trial name
- Thyroid FNAC (NCT05521594)
- Testing
- Fine Needle Aspiration Cytology
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Qena Oncology Center
Thyroid Nodule
Efficacy and Safety of Prunella Oral Liquid in the Treatment of Thyroid Nodules
A multicenter, prospective, randomized, double-blind, placebo-controlled clinical trial was designed to evaluate the efficacy and safety of Prunella oral liquid in patients with benign thyroid nodules, which belongs to the…
- Trial name
- ESPTTN (NCT06423235)
- Testing
- regular dose of JiRui® Prunella oral liquid, 2x regular dose of JiRui® Prunella oral liquid
- Where
- 22 sites in China
- Volunteers
- 234 people
- Sponsor
- Xintian Pharmaceutical
Thyroid Nodule, Thyroid Goiter
Prospective Evaluation of the Pulse Biosciences nPulse™ Vybrance™ Percutaneous Electrode System
The primary objective of this study is to reproduce in a multi-center study results obtained during the feasibility First-In-Human (FIH) study with Prof.
- Conditions
- Thyroid Nodule, Thyroid Goiter, Ablation
- Trial name
- PRECISE-BTN (NCT07287176)
- Testing
- nPulse Vybrance Percutaneous Electrode System
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- Pulse Biosciences, Inc.
Diabetes Mellitus, Type 2, Thyroid Nodule (Benign)
Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules in Type 2 Diabetes
A 2-years prospective, randomized and multicentric study will be performed to assess the efficacy of metformin compared to sitagliptin on benign thyroid nodules size ≥ 2 cm, in newly diagnosed patients with type 2 diabetes.
- Trial name
- METNODTHYR (NCT04298684)
- Testing
- METFORMIN, Sitagliptin
- Where
- 4 sites in France, Guadeloupe and 1 more
- Volunteers
- 90 people
- Sponsor
- Centre Hospitalier Universitaire de la Guadeloupe
Thyroid Nodule
Intervention in Single Thyroid Nodule.
Thyroid nodules are common clinical problem. The incidence is 2-4 per 100,000 people per year, being more common in women and the elderly.
- Trial name
- NCT05658809
- Testing
- thyroidectomy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Thyroid Nodule
Artificial Intelligence-assisted Contrast-enhanced Ultrasound Diagnosis of Thyroid Nodules
The goal of this intervention study is to learn about the diagnostic performance of artificial intelligence to assist the contrast-enhanced ultrasound diagnosis of thyroid nodules. The main questions it aims to answer are: 1.
- Trial name
- AIA-CEUD-TN (NCT05982821)
- Testing
- Artificial Intelligence
- Where
- China
- Volunteers
- 1,955 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Thyroid Nodule
Comparison Between Combined Scoring of Bethesda Cytology and TIRADS Ultrasound With Histopathology in Thyroid Nodule
A thyroid nodule is a discrete lesion within the thyroid gland that is radiologically distinct from the surrounding thyroid parenchyma. Most thyroid nodules are benign, with only 10% to 15% harboring cancer.
- Trial name
- TIRADS (NCT06391021)
- Where
- Nepal
- Volunteers
- 42 people
- Sponsor
- Tribhuvan University, Nepal