Clinical trials: Thyroid Surgeries
Hyperalgesia
Effect of Propofol on Remifentanil-induced Postoperative Hyperalgesia in Patients Undergoing Thyroid Surgery
The investigators hypothesize that propofol infusion during surgery can affect the remifentanil hyperalgesia compared to sevoflurane inhalation.The outcome will be measured by a verbal numerical rating score (VNRS) and mechanical…
- Trial name
- NCT01189721
- Testing
- propofol, sevoflurane
- Where
- South Korea
- Volunteers
- 84 people
- Sponsor
- Gangnam Severance Hospital
Graves Disease, Minimally Invasive Treatment
A Prospective Evaluation of Microwave Ablation (MWA) in the Treatment of Relapsed Graves' Disease
Graves' disease is the most common cause of hyperthyroidism, with conventional treatment options being anti-thyroid drugs (ATD), radioiodine (RAI) and surgery. For ATD, it has been the first-line treatment over decades.
- Conditions
- Graves Disease, Minimally Invasive Treatment, Ablation Treatment
- Trial name
- NCT06506149
- Testing
- Microwave ablation(MWA) device
- Where
- Hong Kong
- Volunteers
- 25 people
- Sponsor
- The University of Hong Kong
Medullary Thyroid Cancer, Prositron Emission Tomography
68Ga-TCR-FAPI PET/CT Guided Precision Surgery for MTC
This is a phase II clinical trial to evaluate the capability of 68Ga-labeled targeted covalent radiopharmaceutical (TCR) fibroblast activation protein inhibitor (FAPI) PET/CT to guide the surgical treatment of medullary thyroid…
- Conditions
- Medullary Thyroid Cancer, Prositron Emission Tomography, Fibroblast Activation Protein Inhibitor, Surgery
- Trial name
- NCT06277180
- Testing
- Surgery
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Thyroid Gland Follicular Carcinoma
Radioiodine Planar and a SPECT/CT Imaging With Iodine-123 for Evaluation of Follicular Thyroid Nodules Prior to Surgery
This study evaluates radioiodine planar and SPECT/CT imaging with iodine-123 in patients with follicular thyroid nodules prior to surgery.
- Trial name
- NCT05591092
- Testing
- Computed Tomography, Iodine I-123, Planar Imaging
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Mayo Clinic
Thyroidectomy
Dysfunction Following Thyroid Surgery
Voice plays a crucial role in human communication and function. Voice production is multidimensional, involving physiologic, biomechanical, and aerodynamic mechanisms that produce an acoustic output that is perceived by the…
- Trial name
- NCT04087447
- Testing
- Thyroidectomy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Thyroid Tumor
Medico-economic Evaluation Comparing the Use of Ultrasonic Scissors to the Conventional Techniques of Haemostasis in Thyroid Surgery by Cervicotomy
The aim of our study is to evaluate the ultrasonic scissors (Harmonic Focus Ethicon Endo-Surgery Laboratory) as a device of hemostasis in thyroid surgery (total thyroidectomy) by cervicotomy, and to show a decrease in transient…
- Trial name
- FOThyr (NCT01551914)
- Testing
- Ultrasonic Scissors (Ethicon), Bipolar Electrosurgical instruments (Medtronic) (SLS- Clips)
- Where
- France
- Volunteers
- 1,350 people
- Sponsor
- Nantes University Hospital
Hashimoto's Disease
Hashimoto - a Surgical Disease. Total Thyroidectomy Makes Antibodies Disappear and Ameliorates Symptoms
The investigators have already proven that absolute total thyroidectomy gives elimination of anti-TPO antibodies. Our hypothesis is that this elimination also eliminates the typical Hashimoto symptoms, namely: Serious tiredness…
- Trial name
- NCT02319538
- Testing
- Total thyroidectomy performed
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Sykehuset Telemark
Papillary Thyroid Microcarcinoma, Radiofrequency Ablation
10 Years' Follow-up Results of Ultrasound-guided Radiofrequency Ablation Versus Surgery for Low-risk Papillary Thyroid Micro-carcinoma
Papillary thyroid micro-carcinoma (PTMC) generally demonstrates favorable prognosis. However, the potential risk of disease progression requires careful therapeutic consideration.
- Conditions
- Papillary Thyroid Microcarcinoma, Radiofrequency Ablation, Surgical Resection, Long-term Outcomes
- Trial name
- NCT07107503
- Testing
- Radiofrequency ablation alone, surgical resection
- Volunteers
- 757 people
- Sponsor
- Yi Mao
Sore Throat, Tracheal Tubes With an Inner Diameter of 6.0mm
Different Models of Tracheal Catheters Are Used for Female Thyroid Glands
Objective:Compare whether the use of tracheal catheters of models 6.0 and 6.5 causes less sore throat in women after thyroid surgery compared with the traditional use of model 7.0 tracheal catheters.Methods: Investigators…
- Conditions
- Sore Throat, Tracheal Tubes With an Inner Diameter of 6.0mm, Tracheal Tubes With an Inner Diameter of 6.5mm, Tracheal Tubes With an Inner Diameter of 7.0mm
- Trial name
- NCT06967896
- Where
- China
- Volunteers
- 180 people
- Sponsor
- Anqing Municipal Hospital
Thyroid Diseases
Dexmedetomidine for Improving Emergence Quality in Thyroid Surgery
Thyroid surgery requires smooth emergence from anesthesia to minimize coughing, hemodynamic fluctuations, and agitation during extubation, which may contribute to postoperative complications such as bleeding or cervical hematoma.
- Trial name
- DEX-THYROID (NCT07462195)
- Testing
- Dexmedetomidine, Standard General Anesthesia
- Where
- Vietnam
- Volunteers
- 100 people
- Sponsor
- Bach Mai Hospital
Papillary Thyroid Cancer, Papillary Thyroid Carcinoma
Active Surveillance and Surgery Outcomes in Low Risk Papillary Thyroid Cancer
This is a prospective, observational, multi-center study examining the long-term outcomes of patients with small, low risk papillary thyroid cancer who offered the choice of active surveillance (close follow-up to monitor for…
- Conditions
- Papillary Thyroid Cancer, Papillary Thyroid Carcinoma, Papillary Microcarcinoma of the Thyroid
- Trial name
- NCT04624477
- Where
- 8 sites in Canada
- Volunteers
- 450 people
- Sponsor
- University Health Network, Toronto
Hypothyroidism
Swallowing Function Before and After Surgery for Thyroid Goiter
To date, there have been no comprehensive studies on swallowing function in patients undergoing surgery for multinodular goiter. We hypothesize that 1.
- Trial name
- NCT00205348
- Volunteers
- 146 people
- Sponsor
- University of Wisconsin, Madison
Virtual Reality Simulation, Thyroid Surgery
The Impact of Immersive Virtual Reality Training in Thyroid Surgery
Up to this date, there have been no reports on virtual reality (VR) training in thyroid surgery. The purpose of this study is to determine the impact of VR training in residents' education.
- Trial name
- NCT06917755
- Testing
- Virtual Reality Training in Thyroid Surgery, Convetional Training
- Where
- Greece
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- G.Gennimatas General Hospital
Thyroid Neoplasms, Thyroid Nodules
Electrical Impedance Scanning of Thyroid Nodules Prior to Thyroid Surgery: a Prospective Study
Patients over the age of 18 with thyroid nodules scheduled for surgery will undergo EIS scan. Each node will be scanned and graded form 1-5 (1=benign, 5=malignant). Results will be compared with final histopathology.
- Trial name
- NCT00571077
- Testing
- Electrical Impedance Scanning (EIS) of the Thyroid gland
- Where
- 2 sites in United States, Israel
- Volunteers
- 200 people
- Sponsor
- Hadassah Medical Organization
Thyroid, Parathyroid Adenoma
Exparel Injection Effect on Postoperative Opioid Usage
The question proposed by this study, is one of patient outcomes. Does intraoperative injection of Exparel decrease postoperative use of opioid pain medications in patients undergoing thyroid and parathyroid surgery? The trial…
- Trial name
- NCT04085913
- Testing
- Lidocaine Epinephrine, Bupivacaine Hydrochloride-EPINEPHrine, Lidocaine Epinephrine, Bupivacaine Hydrochloride-EPINEPHrine
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Thyroid Cancer, Hypoparathyroidism
Study on Application of Suturing Parathyroid Markers in Thyroid Cancer Surgery
To study the protective effect of suture parathyroid marker method on the function of parathyroid gland in thyroid cancer surgery
- Conditions
- Thyroid Cancer, Hypoparathyroidism, Marker; Structural, Complication of Surgical Procedure
- Trial name
- NCT03514251
- Testing
- The suture marks the location of the parathyroid gland
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Bo Wang,MD
Thyroid Disease, Thyroid Surgery
Intraoperative Parathyroid Gland (PTG) Identification Using a Hand-Held Imager (HHI)
It is often challenging to tell apart the parathyroid glands from the surrounding area such as lymph nodes, fat and thyroid tissue.
- Conditions
- Thyroid Disease, Thyroid Surgery, Parathyroid Gland
- Trial name
- NCT06939946
- Testing
- Parathyroid auto-fluorescence imaging, Indocyanine green
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- OPTOSURGICAL, LLC
Thyroid or Parathyroid Surgery
Acupuncture for Reduction of Inflammation
This study is being done because the investigators wish to study ways to improve recovery after surgery. Injury, including surgical injury, causes inflammation.
- Trial name
- NCT01937520
- Testing
- acupuncture, no acupuncture
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Rutgers, The State University of New Jersey
Sleep Deprivation
Characterisation of Gut Microbiota, Bispectral Index Data and Plasma Kynurenine in Patients Undergoing Thyroid Surgery
The study is a case-controlled observational trial. Forty patients will be divided into 2 groups (good or poor sleepers) depending on their first postoperative night Bispectral index data.
- Trial name
- NCT03981770
- Testing
- General anesthesia
- Where
- China
- Volunteers
- 33 people
- Sponsor
- China Medical University, China
Thyroid Associated Ophthalmopathy
Combination of Orbital Compression Surgery and Strabismus Surgery for Thyroid Associated Ophthalmopathy
The purpose of this study is to determine whether combination of orbital compression surgery with strabismus surgery is better than strabismus surgery after orbital compression surgery in the treatment of moderate-to-severe…
- Trial name
- NCT04919694
- Testing
- combination of orbital compression surgery and strabismus surgery, orbital compression
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Sun Yat-sen University