Clinical trials: Thyroid Surgery
Advanced Malignant Thyroid Tumors
rAd-p53 Gene Therapy for Advanced Malignant Thyroid Tumors
This is multicenter, open-label, randomized, active-controled, phase IV study of local direct intra-tumor injection of rAd-p53 monotherapy, with concurrent radioactive iodine , or combination with surgery for treatment of…
- Trial name
- NCT00902122
- Testing
- rAd-p53 gene, surgery, p53 gene therapy
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shenzhen SiBiono GeneTech Co.,Ltd
Endoscopy, Robotics
Comparison Between Robotic, Endoscopic and Traditional Open Surgery in Thyroidectomy
Comparison of endoscopic thyroidectomy, robotic thyroidectomy and conventional open surgery, the safety of the operation, the timing of the operation and the complications.
- Conditions
- Endoscopy, Robotics, Thyroidectomy, Papillary Thyroid Carcinoma
- Trial name
- NCT03454477
- Testing
- conventional open surgery, endoscopic thyroidectomy, robotic thyroidectomy
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Fujian Medical University
Thyroid Diseases, Parathyroid Diseases
The Analysis of Thyroidectomy and Parathyroidectomy
To analyze surgery or not, different surgical methods, timing of surgery, and alternative managements for patients of thyroid or parathyroid disease.
- Trial name
- NCT04569513
- Testing
- Thyroid and parathyroid disease
- Where
- Taiwan
- Volunteers
- 12,000 people
- Sponsor
- National Taiwan University Hospital
Thyroid Cancer
Effect of Perioperative Intravenous Lidocaine Infusion and Magnesium Infusion on the Functional Recovery After General Anesthesia in the Patients Undergoing Thyroid Surgery
Studies have attempted to control pain and increase patients' recovery satisfaction following many kinds of operations by using as small an opioid analgesic dose as possible and adding a nonopioid analgesic to reduce the side…
- Trial name
- NCT02018276
- Testing
- Lidocaine, Magnesium
- Where
- South Korea
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Graves Disease
Does Potassium Iodide (SSKI) Reduce Vascularity in Graves' Thyroidectomy?
The purpose of this research is to find out if SSKI (Potassium Iodide) reduces vascularity (the number and concentration of blood vessels) and improves how well patients do after surgery for removal of their whole thyroid gland…
- Trial name
- NCT04080505
- Testing
- SSKI- Potassium Iodide
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Columbia University
Total Thyroidectomy, Bilateral Neck Exploration for Primary Hyperparathyroidism
Intra-operative Infra-red Fluorescent Imaging in Thyroid and Parathyroid Surgery
Reliable identification of parathyroid glands is critical to the success of thyroid and parathyroid surgery. In thyroid surgery, inadvertent injury to parathyroid glands may cause temporary or permanent hypoparathyroidism (low…
- Trial name
- NCT02089542
- Testing
- MB and fluorescent imaging
- Where
- United Kingdom
- Volunteers
- 41 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Thyroid Nodule, Thyroid Diseases
Oxidized Cellulose Hemostatic Agent in Thyroid Surgery: a Prospective Randomized Controlled Study
This single-blind prospective randomized study was designed to assess the efficacy and safety of the use of Surgicel® compared to the use of conventional surgical procedures (ligatures and bipolar electrocautery alone) to achieve…
- Conditions
- Thyroid Nodule, Thyroid Diseases, Goiter
- Trial name
- NCT01756534
- Testing
- SURGICEL
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Thyroid Nodule
Surgical Versus Non Surgical Management of Thyroid Nodule
To compare between surgical (hemi thyroidectomy and total thyroidectomy) and non-surgical (medical, ethanol injection,thermal ablation and laser photo coagulation) management of simple thyroid nodule regarding: Outcome of every…
- Trial name
- NCT04580199
- Testing
- thyroidectomy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mahmoud Fahd
Thyroidectomy
Thyroid Surgery With the New Harmonic Scalpel: a Prospective Randomized Study
The objective of this study is to compare the results of total thyroidectomy using the new harmonic scalpel device (FOCUS) to that with the previously available harmonic scalpel device (HARMONIC ACE).
- Trial name
- NCT00784407
- Testing
- harmonic scalpel device utilized intraoperatively
- Where
- Greece
- Volunteers
- 90 people
- Sponsor
- Hippocration General Hospital
Thyroid Cancer Stage I
Deciding on Active Surveillance or Surgery for Primary Management of Low Risk Papillary Thyroid Cancer
This is a prospective observational study. 1. In the first part of the study, consenting eligible adult patients with low risk papillary thyroid cancer that is confined to the thyroid, are provided verbal and written information…
- Trial name
- AS-PTC (NCT03271892)
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- University Health Network, Toronto
Goiter
Goitres Influence on Voice Function - The Impact of Surgery
The aim of the study is to investigate the influence benign non-toxic goitre and the surgical treatment hereof on the voice function before and 6 months following surgery.
- Trial name
- SOLOIST (NCT02468921)
- Testing
- Thyroidectomy
- Where
- Denmark
- Volunteers
- 60 people
- Sponsor
- University of Southern Denmark
Acute Pain
Etoricoxib for Postoperative Pain After Thyroid Surgery
The purpose of the study is evaluate the analgesic efficacy and safety profile of the Cox-2 specific analgesic Etoricoxib (arcoxia®) when administrated pre and postoperatively for controlling pain in adult patients undergoing…
- Trial name
- NCT00935116
- Testing
- etoricoxib
- Volunteers
- 70 people
- Sponsor
- Hospital Padre Hurtado
Hypothyroidism, Neoplasms
Levothyroxine Treatment for Subclinical Hypothyroidism After Head and Neck Surgery
Patients that require treatment for cancers of the head and neck often require a combination of surgery and/or radiation and chemotherapy.
- Conditions
- Hypothyroidism, Neoplasms, Postoperative Complications
- Trial name
- LSHT (NCT02548715)
- Testing
- Levothyroxine
- Sponsor
- University of Alberta
Wound Infection
Dexamethasone and Wound Healing After Thyroid Surgery
Dexamethasone is a potent glucocorticoid with analgesic and anti-emetic effects [1-3]. Perioperative single-dose dexamethasone therapy has been used for several purposes: to reduce post-operative nausea and vomiting (PONV), pain…
- Trial name
- NCT02304250
- Testing
- Dexamethasone, saline
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Quanhong Zhou
Thyroid Gland
Diagnostic Value of 18F-Choline PET/CT in Patients With a Thyroid Nodule With an Indeterminate Cytology: Pilot Study
The purpose of the study is to investigate the contribution of PET-CT with F18-choline in the diagnosis of thyroid nodule with indeterminate cytology in order to guide the best indication of surgical resection.
- Trial name
- CHOCOLATE (NCT02784223)
- Testing
- Radiation : PET-CT with F18-choline examination
- Where
- France
- Volunteers
- 107 people
- Sponsor
- Centre Francois Baclesse
Thyroid Cancer, Thyroid Nodule
Educational Videos for Thyroid Surgery Patient
The researchers aim to evaluate the performance of two groups of participants after receiving traditional education-one group supplemented with video-based education and the other without.
- Conditions
- Thyroid Cancer, Thyroid Nodule, TSH, Education of Patients
- Trial name
- NCT07823543
- Testing
- Thyroid Surgery Educational Video
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- West China Hospital
Sore Throat After Thyroid Surgery
Transcutaneous Electrical Acupoint Stimulation on Postoperative Pharyngeal Pain
Thyroid surgery is a common type of surgery in thyroid and breast surgery, mainly used to treat benign and malignant thyroid diseases.
- Trial name
- NCT07117123
- Testing
- Transcutaneous electrical acupoint stimulation, No electrical stimulation
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Thyroid Cancer, Mediastinal Diseases
Lateral Approach for Mediastinal Lymph Node Dissection in Thyroid Cancer
Despite the numerous surgical approaches available for superior mediastinal lymph node dissection in thyroid cancer, many of these methods still have significant limitations.
- Conditions
- Thyroid Cancer, Mediastinal Diseases, Lymph Node Metastasis
- Trial name
- NCT06793579
- Where
- China
- Volunteers
- 21 people
- Sponsor
- Chongqing General Hospital
Thyroidectomy, Thyroid Diseases
BABA Robotic Thyroidectomy Without Gas is Safe Enough as That Use a Gas
In this study, a randomized controlled study was conducted between two groups of 14 classic recipients of Carbon dioxide insufflation during BABA robotic-thyroidectomy and 14 recipients of Gasless method during BABA…
- Trial name
- NCT03922282
- Testing
- Gasless BABA, Classic BABA
- Where
- South Korea
- Volunteers
- 28 people
- Sponsor
- Inje University
Postoperative; Dysfunction Following Cardiac Surgery
Oral Triiodothyronine for Children Undergoing Cardiopulmonary Bypass in Indonesia
A condition of decreased serum T3 level in children after cardiac surgery using cardiopulmonary bypass has been commonly recognized as euthyroid sick syndrome (ESS).
- Trial name
- OTICC (NCT02521168)
- Testing
- Oral triiodothyronine
- Where
- Indonesia
- Volunteers
- 177 people
- Sponsor
- National Cardiovascular Center Harapan Kita Hospital Indonesia