Clinical trials: Thyroid Surgery
Thyroid, Thyroid Nodule
Comparison of TOETVA and Conventional Thyroidectomy
Introduction-Objective: The application of transoral endoscopic thyroidectomy vestibular approach (TOETVA) is gradually increasing recently.
- Conditions
- Thyroid, Thyroid Nodule, Surgery
- Trial name
- TOETVA (NCT04647006)
- Testing
- thyroid
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- MUnlu
Thyroid Cancer
Surgery for Thyroid Cancer With or Without Autofluorescence to Prevent Hypoparathyroidism
The study aims to test if use of autofluorescence imaging (AF) reduces the risk of developing hypoparathyroidism (hypoPT) following surgery for thyroid cancer, either total thyroidectomy (TT) or completion hemithyroidectomy (cHT).
- Trial name
- NCT06222606
- Testing
- Surgery with autofluorescence
- Where
- Denmark
- Volunteers
- 160 people
- Sponsor
- Aarhus University Hospital
Thyroid Disease
NIRF for Parathyroid Visualization: a Pilot Study
During surgery in which the thyroid is removed (thyroidectomy), the identification of parathyroid glands, that should be saved, can be challenging. Therefore, there is need for accurate intraoperative guidance.
- Trial name
- NCT03012438
- Testing
- NIRF imaging in thyroid surgery
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Maastricht University Medical Center
Cholecystitis, Cholecystitis, Chronic
Shortwave Infrared Surgical Imaging Device Study
The goal of this observational study is to perform an in-human assessment of an investigational shortwave infrared (SWIR) imaging device, aimed to enhance the visualization of critical anatomical structures during surgical…
- Conditions
- Cholecystitis, Cholecystitis, Chronic, Chronic Calculous Cholecystitis, Primary Hyperparathyroidism
- Trial name
- NCT07744425
- Testing
- Observational study of SWIR imaging device in surgery
- Where
- 6 sites in United States
- Volunteers
- 50 people
- Sponsor
- Cision Vision, Inc.
Goiter
Changes in Quality of Life Following Surgical Treatment of Benign Non-toxic Goiter
The aim is to investigate the influence of surgical treatment on benign non-toxic goiter on the disease specific quality of life evaluated 6 months after thyroid surgery. All investigations follow already scheduled treatments.
- Trial name
- SOLOIST (NCT02651818)
- Testing
- Thyroidectomy
- Where
- Denmark
- Volunteers
- 104 people
- Sponsor
- University of Southern Denmark
Recurrent Adenoid Cystic Carcinoma of the Oral Cavity, Recurrent Basal Cell Carcinoma of the Lip
Photodynamic Therapy Using HPPH in Treating Patients Undergoing Surgery for Primary or Recurrent Head and Neck Cancer
This phase I trial studies the side effects and best dose of photodynamic therapy using HPPH in treating patients who are undergoing surgery for primary or recurrent head and neck cancer.
- Conditions
- Recurrent Adenoid Cystic Carcinoma of the Oral Cavity, Recurrent Basal Cell Carcinoma of the Lip, Recurrent Esthesioneuroblastoma of the Paranasal Sinus and Nasal Cavity, Recurrent Inverted Papilloma of the Paranasal Sinus and Nasal Cavity
- Trial name
- NCT00470496
- Testing
- HPPH, photodynamic therapy, conventional surgery
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Roswell Park Cancer Institute
Thyroid Diseases, Parathyroid Diseases
PaThERAS: ERAS Protocols in Thyroid & Parathyroid Surgery
Enhanced recovery after surgery (ERASP) are evidence-based perioperative protocols devised to expedite postoperative recovery and discharge, decrease surgical stress and costs.
- Conditions
- Thyroid Diseases, Parathyroid Diseases, ERAS
- Trial name
- PaThERAS (NCT06274970)
- Testing
- Enhanced recovery protocols, Conventional Protocols
- Where
- India
- Volunteers
- 96 people
- Sponsor
- Sanjay Gandhi Postgraduate Institute of Medical Sciences
Thyroid Cancer
Lateral Cervical Node Dissection in Differentiated Thyroid Cancer.
The objective of this study is to compare shoulder and neck morbidity and the effectiveness of cervical lateral nodal dissection in patients with differentiated thyroid cancer and lateral metastases between the anterior and…
- Trial name
- NCT06149637
- Testing
- Traditional neck dissection approach, Anterior neck dissection approach
- Where
- Colombia
- Volunteers
- 62 people
- Sponsor
- Centro de Excelencia en Enfermedades de Cabeza y Cuello
Surgery, Thyroid
The Effects of Different Degrees of Head-of-bed Elevation
The patient's position is important for ensuring patient comfort and preventing complications after thyroidectomy. This study was carried out to determine the effects of different degrees of head-of-bed elevation on the…
- Conditions
- Surgery, Thyroid, Nursing Caries
- Trial name
- NCT03816371
- Testing
- Head-of-bed elevation
- Volunteers
- 114 people
- Sponsor
- Necmettin Erbakan University
Difficult Airway Intubation, Airway Management During Operative Procedure
Comparison of Video Laryngoscopy and Conventional Laryngoscopy for Safe Intubation in Adult Thyroid Surgery Patients With Anticipated Difficult Airway
This clinical study is designed to compare two different techniques used for inserting a breathing tube (a process known as intubation) in adult patients undergoing thyroid surgery who are predicted to have a difficult airway.
- Trial name
- NCT07113171
- Testing
- Conventional Direct Laryngoscope, Video Laryngoscope
- Where
- Pakistan
- Volunteers
- 60 people
- Sponsor
- Sheikh Zayed Medical College
Voice Disorder Due to Iatrogenic Factor, Endotracheal Intubation During Surgery
Objective and Perceptual Characteristics of the Voice After Endotracheal Intubation in Head and Neck Surgery
Introduction: Possible consequences of endotracheal intubation are post-intubation voice changes. Hypothesis: Endotracheal intubation during head and neck surgery is associated with objective and perceptual voice disorders.
- Conditions
- Voice Disorder Due to Iatrogenic Factor, Endotracheal Intubation During Surgery, Thyroid Surgery, Head and Neck Surgery
- Trial name
- VOICE (NCT07131800)
- Where
- Croatia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Centre Zagreb
Surgery
Video-assisted Thyroid Surgery and Hypnosis in Thyroid Surgery
The study is aimed to investigate the safety and feasibility of Video-assisted thyroidectomy under hypnosis in comparison to general anesthesia
- Trial name
- NCT01752283
- Testing
- video-assisted thyroidectomy
- Where
- Belgium
- Volunteers
- 130 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Thyroid Cancer, Hypoparathyroidism
Near-Infrared Autofluorescence With PTH Test Strip as an SOP of Parathyroid in Thyroid Surgery
This is a prospective study aiming to establish near-infrared autofluorescence technology and PTH test strip as a standardized process for finding and identifying parathyroid glands in thyroid surgery.
- Conditions
- Thyroid Cancer, Hypoparathyroidism, Optical Imaging
- Trial name
- PTFINDER (NCT05684029)
- Testing
- Near-infrared devices, PTH test strip
- Where
- China
- Volunteers
- 101 people
- Sponsor
- Fujian Medical University
Thyroid Cancer
Assessing Patient Satisfaction and Confidence After Use of Educational Video to Augment Surgical Consent for Thyroid Surgery
This study looks at how a short educational video can help people better understand thyroid surgery. Patients who have thyroid nodules and need surgery will be part of the study.
- Trial name
- TISCAV (NCT06918223)
- Testing
- Thyroid Informed Surgical Consent Augmenting Video (TISCAV), Standard Consent
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Thomas Jefferson University
Thyroid Cancer, Papillary Thyroid Carcinoma
Active Surveillance for Low-risk Papillary Thyroid Carcinoma
This is a multi-center, non-randomized, prospective observational cohort study aimed at establishing a cohort of low-risk papillary thyroid cancer patients with a maximum tumor diameter of 1.5 cm or less, consisting of an active…
- Trial name
- MAeSTro-EXP (NCT06261190)
- Where
- 4 sites in South Korea
- Volunteers
- 499 people
- Sponsor
- National Cancer Center, Korea
Papillary Thyroid Carcinoma
Single-Incision Gasless Endoscopic Total Thyroidectomy Via Subclavian Approach Versus Open Surgery for PTC
Historically, performing a contralateral thyroid lobectomy and lymph node dissection via the subclavian approach was considered challenging.
- Trial name
- NCT06592755
- Testing
- single-incision, gasless endoscopic total thyroidectomy with central compartment neck dissection, conventional open surgery
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Thyroid Disease, Parathyroid Disease
Complications of Endocrine Surgery: Data From the United HealthSystem Consortium
The goal of this study is to help better determine the complication rates for endocrine surgery across the nation for both benign and malignant disease.
- Conditions
- Thyroid Disease, Parathyroid Disease, Endocrine Gland
- Trial name
- NCT01539499
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- University of Arkansas
Thyroid
Secured Thyroidectomy With Intraoperative Methylene Blue Using
Thyroid surgery has potential risks. Intraoperative organ (such as parathyroides) extraction and vascular or neural (such as recurrent nervus) injuries are most important ones.
- Trial name
- bluethyroid (NCT01347606)
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- SB Istanbul Education and Research Hospital
Thyroid Disease
Individualized Supramaximal Stimulation Current During Continuous Neuromonitoring in Thyroid Surgery
Continuous intraoperative neuromonitoring (C-IONM) is increasingly used during thyroid surgery to detect early changes in recurrent laryngeal nerve function and reduce the risk of nerve injury.
- Trial name
- CIONM-SSC (NCT07710365)
- Testing
- Continuous intraoperative neuromonitoring with fixed stimulation current, Continuous intraoperative neuromonitoring with individualized stimulation current
- Where
- Poland
- Volunteers
- 623 people
- Sponsor
- Medical University of Gdansk
Benign Neoplasm of Thyroid Gland, Malignant Neoplasm of Thyroid
Dexamethasone for the Prevention of Recurrent Laryngeal Nerve Palsy
Recurrent laryngeal nerve dysfunction and hypoparathyroidism are well-recognized important complications of thyroid surgery. The duration of convalescence, after non complicated thyroid operation, may depend on several factors of…
- Trial name
- NCT01690806
- Where
- Italy
- Volunteers
- 328 people
- Sponsor
- Università degli Studi dell'Aquila