Clinical trials: Tibial Nerve
Urge Urinary Incontinence, Overactive Bladder (OAB)
Effect of Neuromodulation and Therapeutic Exercise in Urinary Incontinence
Urge urinary incontinence (UUI) is a component of the condition known as overactive bladder, a severe and debilitating chronic disorder affecting healthcare systems worldwide.
- Trial name
- UCV/INCONTINEN (NCT06783374)
- Testing
- Neuromodulation, Exercise, Exercise control group
- Where
- Spain
- Volunteers
- 63 people
- Sponsor
- Fundación Universidad Católica de Valencia San Vicente Mártir
Premature Ejaculation, Sex Disorder
Effectiveness and Safety of TENS Therapy for Premature Ejaculation
The objective of this clinical trial is to evaluate the effectiveness and safety of transcutaneous posterior tibial nerve stimulation therapy in patients with premature ejaculation.
- Conditions
- Premature Ejaculation, Sex Disorder, TEN
- Trial name
- TENSPE2 (NCT06425224)
- Testing
- Tens therapy, Standard treatment (dapoxetine 30 mg as needed)
- Where
- Mexico
- Volunteers
- 129 people
- Sponsor
- Boston Medical Group
Constipation, Childhood ALL
PTNS and PFR in the Treatment of Childhood Constipation
Constipation is the most common complaint in childhood, affecting an estimated 20% of children globally. At present, the treatment of children's constipation is full of challenges, and treatment methods are diverse.
- Conditions
- Constipation, Childhood ALL, Pelvic Floor Disorders
- Trial name
- NCT05059756
- Testing
- PTNS
- Where
- China
- Volunteers
- 84 people
- Sponsor
- Shengjing Hospital
Urge Urinary Incontinence
COMPARATIVE EFFICACY OF ELECTROMAGNETIC FIELD THERAPY AND TIBIAL NERVE STIMULATION IN URGE URINARY INCONTINENCE
Urge urinary incontinence is a prevalent condition characterized by involuntary leakage of urine accompanied by a sudden, compelling urge to void.
- Trial name
- NCT07536139
- Testing
- Magnetic Field Therapy (PEMF), Posterior Tibial Nerve Stimulation (PTNS), Pelvic Floor Muscle Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Overactive Bladder
Percutaneous Tibial Nerve Stimulation Maintenance: Monthly Therapy or Per Patient Requested Need
The overall objective of this study is to compare the efficacy of the standard monthly maintenance therapy for percutaneous tibial nerve stimulation (PTNS), to sessions as the patient needs (prn) between 2 weeks and 12 weeks…
- Trial name
- NCT03136601
- Testing
- PTNS maintenance
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Multiple Sclerosis, Relapsing-Remitting
Wireless, Implantable Tibial Nerve Stimulator System for the Treatment of Refractory Lower Urinary Tract Symptoms in Patients With Multiple Sclerosis
Prevalence of lower urinary tract symptoms (LUTS) in patients with multiple sclerosis (MS) increases with disease duration. Current management of urinary clinical symptoms in MS is mainly conservative.
- Trial name
- Stimrouter (NCT04567264)
- Testing
- StimRouter®, Self-activated and self-controlled neuromodulation device (Bioness Inc, CE0086).
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Chiara Zecca
Overactive Bladder (OAB), Refractory Overactive Bladder
Cefar URO - Symptomatic Treatment of Overactive Bladder
A Post-Market Prospective Clinical Investigation to collect PMCF data on the safety and performance of the Cefar URO device when using the preset program P4 (parameter setting: frequency 20Hz, pulse width 200μs) for the…
- Conditions
- Overactive Bladder (OAB), Refractory Overactive Bladder, Urinary Urgency and Frequency
- Trial name
- NCT06659536
- Testing
- Transcutaneous Tibial Nerve Stimulation (TTNS) with the Cefar Uro Device
- Where
- France
- Volunteers
- 53 people
- Sponsor
- DJO UK Ltd
Ankle/Foot Surgery
Ultrasound Guided Popliteal Fossa Block. Does Blockade Distal to Sciatic Nerve Bifurcation Speed Onset Time? A Prospective, Randomized Trial
Sciatic nerve block is used routinely in ankle and foot surgery. It is applied often by a posterior approach at the popliteal fossa, near where the nerve divides into the common peroneal and tibial nerves.
- Trial name
- NCT00803426
- Testing
- Sciatic nerve blockade for ankle/foot surgery
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- University Health Network, Toronto
Fecal Incontinence
Comparison of PTNS and Biofeedback for Fecal Incontinence
Until recently, there is no definite treatment for fecal incontinence that is proven to be effective with low morbidity. The efficacy of biofeedback therapy for incontinence has not been proven on the randomized controlled…
- Trial name
- NCT01882101
- Testing
- Posterior tibial nerve stimulation, Biofeedback
- Where
- 6 sites in South Korea
- Sponsor
- Seoul National University Hospital
Neurogenic Bladder Dysfunction
Transcutaneous Tibial Nerve Stimulation for Treating Neurogenic Lower Urinary Tract Dysfunction
Many patients with neurological diseases suffer from neurogenic lower urinary tract dysfunction (NLUTD), which often severely impairs quality of life, due to urinary urgency with or without incontinence and voiding dysfunction.
- Trial name
- NCT02859844
- Testing
- Transcutaneous Tibial Nerve Stimulation (TTNS)
- Where
- 2 sites in Switzerland
- Volunteers
- 9 people
- Sponsor
- University of Zurich
Overactive Bladder
Add-On ZIDA Sock Therapy for Overactive Bladder
Many people with overactive bladder (OAB) continue to experience symptoms despite pharmacologic treatment. This study evaluates the use of the ZIDA Control Sock, an FDA-cleared, noninvasive wearable device that delivers mild…
- Trial name
- NCT07432659
- Testing
- ZIDA Control Sock
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical University of South Carolina
Dysmenorrhea Primary
Transcutaneous Tibial Nerve Stimulation as Treatment for Women With Primary Dysmenorrhea
The goal of this study is to verify whether transcutaneous stimulation of the posterior tibial nerve improves pain, quality of life and sleep deficiency in patients with pain related to their menstrual period in the short and…
- Trial name
- NCT04896814
- Testing
- Transcutaneous tibial nerve stimulation
- Where
- Spain
- Volunteers
- 55 people
- Sponsor
- University of Salamanca
Urge Incontinence, Overactive Bladder
Transcutaneous Tibial Nerve Stimulation for Urgency Urinary Incontinence
This is a single-center, double-blinded, randomized controlled trial evaluating the efficacy of TTNS versus a sham intervention. Both interventions will be performed by participants in their homes after standardized instruction.
- Trial name
- TTeNS (NCT04936464)
- Testing
- transcutaneous tibial nerve stimulation (TTNS), transcutaneous electrical stimulation (TENS)
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Kaiser Permanente
Anterior Cruciate Ligament Injuries, Postoperative Pain
Postoperative Analgesic Efficacy of ACB+iPACK vs FTB+Selective Tibial+Obturator Blocks in ACL Reconstruction
This prospective, comparative study aims to evaluate the postoperative analgesic efficacy of ultrasound-guided Adductor Canal Block (ACB) combined with iPACK block versus Femoral Triangle Block (FTB) combined with selective…
- Trial name
- ACL-Analgesia (NCT07702552)
- Testing
- Ultrasound-guided Adductor Canal Block (ACB), Ultrasound-guided iPACK block, Ultrasound-guided Femoral Triangle Block (FTB)
- Volunteers
- 100 people
- Sponsor
- Da Nang Hospital
Multiple Sclerosis, Lower Urinary Tract Symptoms
PTNS on Urinary and Global Quality of Life in MS Patients
This is a single-centered, prospective, longitudinal, observational cohort study of patients with MS who suffer from lower urinary tract symptoms (LUTS) and are refractory to two prior treatment modalities who have elected to…
- Conditions
- Multiple Sclerosis, Lower Urinary Tract Symptoms, Neurogenic Bladder, Overactive Bladder
- Trial name
- PTNSinMS (NCT04063852)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Michigan
Over Active Bladder
Stimulating Percutaneous Array for Urinary Reflex Control (SPARC)
The Confidanz Smart Patch System consists of a Smart Patch containing one transcutaneous gel electrode and one percutaneous microneedle array electrode that sits directly superficial to the posterior tibial nerve.
- Trial name
- NCT07149103
- Testing
- Percutaneous Tibial Nerve Stimulation
- Where
- 2 sites in Australia
- Volunteers
- 40 people
- Sponsor
- Australis Scientific PTY LTD
Diabetic Peripheral Neuropathy, Diabetes Mellitus
Effects of Glycemic Control and Clinical Parameters on Tibial Nerve Conduction Latency in Diabetic Peripheral Neuropathy
This observational cross-sectional study aims to investigate the effects of glycemic control and clinical parameters on tibial nerve conduction latency in individuals with diabetic peripheral neuropathy.
- Trial name
- NCT07525882
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Fenerbahce University
Hallux Valgus and Bunion (Disorder), Morton Neuroma
Feasibility of Specific Anesthesia of the Forefoot Preserving the Sensitivity of the Heel for Foot Surgery
Foot surgery is a painful surgery that is usually scheduled in outpatients. A good management of analgesia is the crucial point.
- Conditions
- Hallux Valgus and Bunion (Disorder), Morton Neuroma, Metatarsal Fracture, Ingrown Nail
- Trial name
- DISTIB (NCT03504462)
- Testing
- Specific block of medial and lateral plantar nerves
- Where
- France
- Volunteers
- 27 people
- Sponsor
- CMC Ambroise Paré
Obstructed Defecation
Obesity on the Efficacy of Bilateral Tibial Nerve Stimulation
Obstructed defecation syndrome (ODS) is a common functional bowel disorder characterized by difficulty in stool evacuation. Bilateral posterior tibial nerve stimulation (BT PTNS) has emerged as a noninvasive, safe, and effective…
- Trial name
- NCT07390682
- Testing
- Bilateral posterior tibial nerve stimulation
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt
Urinary Incontinence, Urge
CAN-Stim Compared to SNS in Treatment of Urinary Urgency Incontinence With Wireless Neuromodulation Technology
This is a prospective, randomized, controlled, multi-center, study in which 150 evaluable subjects will be randomized 1:1 to receive either a Protect CAN-Stim or SNS InterStim® system.
- Trial name
- PROTECT (NCT02577302)
- Testing
- CAN-Stim - Protect CAN-Stim System, SNS - InterStim® System
- Where
- 15 sites in United States
- Volunteers
- 200 people
- Sponsor
- Uro Medical Corporation