Clinical trials: Time Management
Overweight , Obesity
Research on the Needs, Feasibility, and Intervention Effects of AI Health Coach-based Just-in-Time Adaptive Intervention (JITAI) in Weight Management for Overweight/Obese Adults
This pilot study evaluates the needs, feasibility, and preliminary effects of an artificial intelligence (AI) health coach-based just-in-time adaptive intervention for weight management in adults with overweight or obesity.
- Trial name
- NCT07682571
- Testing
- AI Health Coach-based Just-in-Time Adaptive Intervention
- Where
- China
- Volunteers
- 31 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Chronic Pain
A Study To Observe The Performance Of A Tablet Form Of PF-04531083 As Evidenced By The Concentration Of PF-04531083 In The Blood With Time Following Oral Administration To Healthy Volunteers.
A new tablet form of PF-04531083 has been manufactured. Previously the compound was administered as a solution/suspension to healthy volunteers.
- Trial name
- NCT01119235
- Testing
- PF-04531083
- Where
- Belgium
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Pfizer
Shock, Septic
Effect of Albumin Administration on Vasopressor Duration in Resolving Septic Shock
The role of albumin in sepsis has been controversial for decades. Although hypoalbuminemia has been associated with worse outcomes in sepsis, definitive evidence does not exist that replacing albumin in these patients improves…
- Trial name
- NCT02716597
- Testing
- 25% Albumin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Alexander Flannery, 859-323-4011
Intraoperative Fluid Volume, Hemodynamics
Pulse Pressure Variation Based Intraoperative Fluid Management Versus Traditional Fluid Management for Colonic Cancer Patients Undergoing Mass Resection and Anastomosis
pulse pressure variation based intraoperative fluid therapy versus traditional fluid therapy for colonic cancer patients undergoing mass resection and anastomosis for maintaining adequate hydration without complications.
- Conditions
- Intraoperative Fluid Volume, Hemodynamics, Serum Lactate, Intestinal Edema
- Trial name
- NCT05502835
- Testing
- pulse pressure variation, conventional fluid management
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Small Bowel Obstruction
SnapSBO - Small Bowel Obstruction Snapshot Audit
Small bowel obstruction (SBO) and its complications are frequently seen in patients admitted through the Emergency Departments of all acute care hospitals2.
- Trial name
- SnapSBO (NCT05843097)
- Where
- Spain
- Volunteers
- 1,900 people
- Sponsor
- European Society for Trauma and Emergency Surgery
Medical Induction of Labor Affecting Fetus
Effect Of Intra-muscular Administration of Dexamethasone in Induction of Labour
ABSTRACT: Objective: To evaluate the efficacy of dexamethasone on labor duration and to establish whether dexamethasone plays a role in shorting the duration interval between initiation of labor induction and beginning of the…
- Trial name
- NCT02508402
- Testing
- Dexamethasone
- Where
- Egypt
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Calciphylaxis, Renal Insufficiency, Chronic
The Early Administration of Sodium Thiosulfate Should Help to Reduce the Mortality of Dialysis Patients With Calciphylaxis, From a National Cohort
The national drug safety agency authorizes nominatively the use of sodium thiosulfate in dialysis patients with calciphylaxis. To date, it is the largest global cohort (more 600 patients from 2012 to 2016).
- Trial name
- NCT03146793
- Testing
- Sodium Thiosulfate
- Where
- France
- Volunteers
- 600 people
- Sponsor
- Centre Hospitalier St Esprit
Obstructive Sleep Apnea
Evaluation of an Early Management Strategy for Obstructive Sleep Apnea
The primary objective of this study is to evaluate the effect of more timely care for obstructive sleep apnea (OSA) on adherence to positive airway pressure (PAP) therapy at three months after treatment initiation.
- Trial name
- NCT04613414
- Testing
- Early Management
- Where
- Canada
- Volunteers
- 103 people
- Sponsor
- University of Calgary
Management of Anticoagulation
Improved Time in Therapeutic Range With Patient Self-Testing of Their INR Compared to Usual Care
Patients who receive a mechanical heart valve to replace a diseased heart valve must take an anticoagulation medicine the rest of their lives, and monitor their level of anticoagulation.
- Trial name
- NCT00703963
- Testing
- INRatio monitor by Hemosense, Usual Care
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Bacterial Infections, Fungal Infections
MALDITOF Versus Routine Clinical Microbiology for Identifying Pathogens; a Randomized Diagnostic Trial
MALDI-TOF MS is capable of directly identifying bacteria and fungi in positive blood cultures, which may be beneficial to patient management.
- Trial name
- MALDITOF (NCT02306330)
- Testing
- Malditof, Routine clinical microbiology
- Where
- 2 sites in Vietnam
- Volunteers
- 802 people
- Sponsor
- Oxford University Clinical Research Unit, Vietnam
Fractures, Closed, Wounds and Injuries
Antibiotic Prophylaxis in Orthopaedic Traumatology
It has been established that providing antibiotic prophylaxis after closed fracture fixation with implants or prosthetic devices has beneficial effects.
- Trial name
- NCT00610987
- Testing
- cefazolin
- Where
- United States
- Volunteers
- 178 people
- Sponsor
- University of Missouri-Columbia
Relapsing Forms of Multiple Sclerosis
Time and Motion Study for Ocrelizumab and Ofatumumab Administration in Relapsing Multiple Sclerosis
This is an observational cross-sectional study of Ocrelizumab or Ofatumumab administrations for Relapsing forms of Multiple Sclerosis (RMS) in selected sites in the US, the UK and Australia.
- Trial name
- TIMIOS (NCT04676555)
- Testing
- Ocrelizumab, Ofatumumab
- Where
- 2 sites in United States, Australia
- Volunteers
- 2 people
- Sponsor
- Novartis Pharmaceuticals
Schizophrenia
A Study Of The Safety, Tolerability And Pharmacokinetics Of Single Doses Of PF-05180999 In Healthy Adults
The purpose of this study is to determine the safety, tolerability, and pharmacokinetics of 14 days of treatment with PF-05180999 in healthy subjects.
- Trial name
- NCT01429740
- Testing
- PF-05180999
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Pfizer
Type 2 Diabetes
Almonds and Diabetes Management
This trial examined the impact of acute and chronic almond ingestion on indicators of glucose control (postprandial glycemia and hemoglobin A1c). Hypotheses: 1.
- Trial name
- NCT01161030
- Testing
- Almonds
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Unexplained Infertility
Dual FSH/HCG Trigger in Letrozole Stimulated Intrauterine Insemination Cycles in Women With Unexplained Infertility
The objective of this study was to evaluate the outcome of follicle stimulating hormone (FSH) co-administration with human chorionic gonadotrophins trigger for women with unexplained infertility (UEI) and assigned for letrozole…
- Trial name
- NCT02739516
- Testing
- Human chorionic gonadotropin, FSH co-trigger, Letrozole
- Volunteers
- 108 people
- Sponsor
- Benha University
Pregnancy Outcome, Time-to-Pregnancy
2.Comparison of the Live Birth Rate of PGT Versus Expectant Management in Patients With RPL
Recurrent pregnancy loss (RPL) is a multifactorial disorder defined by the American Society for Reproductive Medicine (ASRM) as two or more clinical miscarriages (CMs).
- Trial name
- NCT05457335
- Testing
- undergoing PGT
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Artificial Abortion, PONV(Post Operative Nausea and Vomiting)
The Time Point of Carboprost Methylate Administration and Perioperative Complications
Artificial abortion is the most widely used procedure in termination of first-trimester pregnancy. Cervical ripening before the operation guarantees operative convenience and decreases complications.
- Trial name
- NCT05834361
- Testing
- early vaginal administration of carboprost methylate, delayed vaginal administration of carboprost methylate
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Sickle Cell Disease, Depression
Cognitive Behavioral Therapy and Real-time Self-management Intervention for SCD Via Mobile Applications
Patients with sickle cell disease (SCD) experience significant depressive symptoms that currently go unrecognized and under-treated.
- Conditions
- Sickle Cell Disease, Depression, Anxiety
- Trial name
- CaRISMA (NCT02384590)
- Testing
- Computerized cognitive behavioral therapy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Hepatitis C
A First Time in Human Study to Assess the Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of Single and Repeat Doses of GSK2485852 in Chronically Infected Hepatitis C Subjects
GSK2485852 is a Hepatitis C NS5B site IV non-nucleoside polymerase inhibitor being developed for the treatment of chronic HCV infection.
- Trial name
- NCT01332552
- Testing
- GSK2485852 70 mg, GSK2485852 420 mg, GSK2485852 630 mg
- Where
- 5 sites in United States
- Volunteers
- 27 people
- Sponsor
- GlaxoSmithKline
Appendicitis, Child
CT Scan Using IV Contrast Alone for Pediatric Appendicitis
Computed tomography (CT) scan using intravenous contrast (CT IV) as the sole type of contrast material, was studied as one method of evaluating children with suspected appendicitis.
- Conditions
- Appendicitis, Child, Contrast Media
- Trial name
- NCT00716703
- Testing
- CT Scan using IV contrast alone
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Rochester