Clinical trials: Time Management
Paralytic Lagophthalmos
A Real-Time Magnetic Device Prototype for Temporary Management of Paralytic Lagophthalmos
To develop a real-time wearable device based on the principle of magnetic force for temporary management of lagophthalmos, and evaluate its efficacy and safety, including synchronous blinks and eye closure, blurred vision…
- Trial name
- NCT03848260
- Testing
- Magnetic device prototype
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- E-DA Hospital
Pain, Postoperative
Ketamine Effects as Preemptive Analgesia
The goal of this randomized controlled trial is to compare the effect of preemptive ketamine administration to placebo administration in patients underwent hysterectomy surgery. The main questions it aims to answer are: 1.
- Trial name
- NCT06040060
- Testing
- Ketamine
- Where
- Indonesia
- Volunteers
- 40 people
- Sponsor
- Universitas Padjadjaran
Propofol Adverse Reaction, Anesthesia
Impact of Propofol Reduction in Anesthesia Induction
Objective: Determine if, by reducing the dose of propofol and increasing the time elapsed between fentanyl and propofol administration, hemodynamic response is improved.
- Trial name
- NCT04194151
- Testing
- Propofol Injection
- Where
- Spain
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Hospital Central de la Defensa Gómez Ulla
Drug Effect
A Pilot Study for Optimizing Meropenem Administration in the ICU
Can antibiotic drugs be administered faster and make acceptable serum concentrations if we give short but multiple infusions compared to long and fewer infusions? In this study we will compare giving meropenem 1 gram 6 times…
- Trial name
- MER6 (NCT05578586)
- Testing
- Meropenem 1000 mg
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Oslo University Hospital
Asthma
A Study to Compare the Efficacy and Safety of Different Dosings of Olodaterol Administered With the Respimat® Inhaler in Patients With Moderate to Severe Asthma
This study will compare efficacy and safety of different regimens of olodaterol administration in asthma (once daily, twice daily) with placebo in a complete cross-over design each within one of the two daily dose groups (medium…
- Trial name
- NCT01311661
- Testing
- Olodaterol low daily dose twice daily, Olodaterol medium daily dose twice daily
- Where
- 36 sites in United States, Austria and 4 more
- Volunteers
- 206 people
- Sponsor
- Boehringer Ingelheim
Labor Long, Labor Pain
Comparison of Combined Spinal-epidural Analgesia Versus Epidural Analgesia for Pain Management During Labor
The investigators want to compare the safety and efficacy between the combined spinal-epidural analgesia and epidural analgesia during labor.
- Conditions
- Labor Long, Labor Pain, Labor Fetal Anoxia
- Trial name
- NCT03600272
- Testing
- Combined spinal-epidural analgesia, Epidural analgesia
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Deng Dongrui
Pulmonary Disease, Chronic Obstructive
Real-Time Telehealth to Promote Self-care Management for Chronic Obstructive Pulmonary Disease
HYPOTHESIS:The study purpose is to evaluate the effectiveness of a structured pursed-lips breathing (PLB) protocol taught via real-time interactive telecommunication with a home computer using the lnternet and Skype software in…
- Trial name
- E-Breathe (NCT01161290)
- Testing
- synchronous interactive audio/video telecommunication
- Volunteers
- 22 people
- Sponsor
- Breathe California, Los Angeles County
Multiple Myeloma, Peripheral Neuropathy
Evaluation of Bortezomib Induced Peripheral Neuropathy of Multiple Myeloma (MM) Patients
In the present study we are planning to study electrophysiological changes related to the dose and time of bortezomib administration in newly diagnosed patients with MM, during the first months of treatment and 6 months after…
- Trial name
- NCT00872352
- Testing
- EMG
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Wolfson Medical Center
Healthy Subjects
A Study in Healthy Male Subjects to Investigate Whether Administration of ACT-541468 Can Affect the Fate in the Body (Amount and Time of Presence in the Blood) of Rosuvastatin
A study in healthy male subjects to investigate whether administration of ACT-541468 can affect the fate in the body (amount and time of presence in the blood) of rosuvastatin
- Trial name
- NCT03339752
- Testing
- Rosuvastatin, ACT-541468
- Where
- Czechia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Idorsia Pharmaceuticals Ltd.
Weight, Body
Time Restricted Eating With or Without a Fiber Supplement for Weight Management in Pediatric Cancer Survivors
This study aims to address a critical gap in pediatric oncology survivorship care by exploring innovative solutions to addressing obesity and its comorbidities in pediatric cancer survivors.
- Trial name
- NCT05826184
- Testing
- Time restircted eating, Time restricted eating + prebiotic
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Acute Ischemic Stroke, Large Vessel Occlusion
Direct Angio Suite Acute Stroke Intervention With CT/DSA Hybrid Emergency Stroke Unit
This study investigates whether direct transfer to an emergency stroke unit equipped with NeuAngio-CT reduces time to endovascular reperfusion in patients with acute ischemic stroke and suspected intracranial large-vessel…
- Trial name
- NCT07670065
- Testing
- Direct Angio Suite Acute Stroke Intervention With CT/DSA Hybrid Emergency Stroke Unit, Conventional Thrombectomy
- Where
- China
- Volunteers
- 232 people
- Sponsor
- Beijing Tiantan Hospital
Healthy
Single Increasing Dose Followed by Maintenance Dose Tolerance Study of BIIR 561 CL in Healthy Male Volunteers
The objective of the present study is to obtain information about the safety, tolerability and pharmacokinetics of BIIR 561 after continuous intravenous administration of increasing doses in healthy young volunteers
- Trial name
- NCT02222961
- Testing
- BIIR 561 CL
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Unknown Primary Cancer
Review of Molecular Profiling-Real Time Polymerase Chain Reaction (Rt-Pcr) in Unknown Primary Cancer
This will be a retrospective review of 30 patients with unknown primary cancer who have had commercially available RT-PCR assays performed on biopsied tumors, in order to determine if the assay results are consistent with…
- Trial name
- NCT00876408
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- SCRI Development Innovations, LLC
Healthy
Single Increasing Doses of BIII 890 CL in Healthy Young Male Volunteers and in Healthy Elderly Male and Female Volunteers
Safety, tolerability and pharmacokinetics of BIII 890
- Trial name
- NCT02269215
- Testing
- BIII 890 CL
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Labor Pain
The Effect of Continuous Midwifery-led Care in Birth Management
Caesarean section is an emergency procedure necessary to prevent harm or death to the mother or newborn. Worldwide, caesarean section rates are steadily increasing.
- Trial name
- NCT06660615
- Testing
- MIDWIFE-LED CARE
- Where
- Turkey (Türkiye)
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Diagnostic Techniques and Procedures, Cardiac Surgical Procedure
Evaluation of a New Sonoclot Device for Heparin Management in Cardiac Surgery
The SONOCLOT Analyzer (S1; Sienco, Inc. Boulder, CO USA, Model DP-2951) is used to perform kaolin-based activated clotting time as routine monitor of heparin therapy in patients undergoing cardiac operations.
- Trial name
- SONEW (NCT02588976)
- Testing
- Sonoclot Analyzer
- Volunteers
- 30 people
- Sponsor
- Triemli Hospital
Single Traumatic Limb Injury With Severe Pain (Score > 5/10 on Numerical Pain Scale)
Intranasal Sufentanil Pain-management at Entrance of Emergency Department : Influence on Pain-relief Delay
Non-invasive and simple, intranasal (IN) route of administration seems promising for pain management in the Emergency Department (ED), especially when used precociously by triage nurse to rapidly deliver the first opioid dose to…
- Trial name
- InSPEED (NCT01954368)
- Testing
- Sufentanil
- Where
- France
- Volunteers
- 144 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Osteoporosis
A Clinical Trial to Evaluate Efficacy of Once or Twice ZOledronic Acid After Different Duration of denOsumMab Administration in Postmenopausal Women With Osteoporosis (ZOOM Study)
Denosumab(Dmab) is a monoclonal antibody that inhibits the receptor-activator of nuclear factor kappa-B ligand. It improves bone density and reduces fractures by inhibiting osteoclast recruitment and differentiation.
- Trial name
- NCT05361408
- Testing
- Zoledronic acid, once, Zoledronic acid, twice
- Where
- South Korea
- Volunteers
- 114 people
- Sponsor
- Yonsei University
Neoplasm Metastasis
Non-interventional Observational Study of Stereotactic Body Radiotherapy (SBRT) for Oligometastatic Cancer
The investigators recently published 2 phase II trials on the use of helical tomotherapy for oligometastatic colorectal cancer [1,2].
- Trial name
- NCT02228356
- Testing
- Stereotactic Body Radiation Therapy
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitair Ziekenhuis Brussel
Parkinson Disease
Real-Time Levodopa Level Monitoring in Parkinson Disease
This project aims to develop a minimally invasive sensor device to monitor levodopa levels in real time. We will test the accuracy, tolerability, and safety of this device in people with Parkinson disease.
- Trial name
- NCT04735627
- Testing
- Levodopameter
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego