Clinical trials: Tinnitus
Subjective Tinnitus
Efficacy, Safety, Tolerability of Neramexane in Patients With Subjective Tinnitus
The purpose of this study is to investigate the safety and efficacy of neramexane mesylate in the treatment of subjective tinnitus in comparison to placebo.
- Trial name
- NCT00955799
- Testing
- Neramexane mesylate
- Where
- 76 sites in United States, Austria and 3 more
- Volunteers
- 455 people
- Sponsor
- Merz Pharmaceuticals GmbH
Tinnitus, Subjective
OTO-313 in Subjects With Subjective Tinnitus
The purpose of this study is to evaluate the safety, tolerability, plasma pharmacokinetics (PK), and exploratory efficacy of OTO-313 administered as an intratympanic injection for the treatment of subjective tinnitus.
- Trial name
- NCT03918109
- Testing
- OTO-313
- Where
- 16 sites in United States
- Volunteers
- 43 people
- Sponsor
- Otonomy, Inc.
Tinnitus, Subjective, Cupping Therapy
Wet Cupping Therapy as an Integrative Medicine Treatment for Subjective Tinnitus
Cupping therapy is an ancient complementary medicine therapy. It was a cornerstone in many ancient healing systems, including Traditional Chinese Medicine, Unani Medicine, Traditional Korean Medicine, and Islamic Medicine.
- Trial name
- NCT07685171
- Testing
- Wet Cupping Therapy plus Usual care, usual care only
- Volunteers
- 142 people
- Sponsor
- Hamad Medical Corporation
Hearing Loss, Noise-Induced, Hearing Loss
Apple Hearing Study
The Apple Hearing Study is a partnership between the University of Michigan and Apple to study sound exposure and its impact on hearing health.
- Conditions
- Hearing Loss, Noise-Induced, Hearing Loss, Tinnitus
- Trial name
- AHS (NCT04172766)
- Where
- United States
- Volunteers
- 300,000 people, healthy volunteers welcome
- Sponsor
- Apple Inc.
Tinnitus
Assessing Factors in Tinnitus Patients' Clinical Study Experiences
Clinical trials can sometimes favor certain demographic groups. Additionally, there is limited research that delves into the factors that influence participation in clinical trials, both positive and negative.
- Trial name
- NCT05811871
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Tinnitus, Hearing Disorders
Evaluation of Potential Causes of Nap Modulated Tinnitus
The proposed research is a non-interventional study made to evaluate different measurements on 1 group of participants, before and after taking a nap, aiming to potentially guide future investigations on nap-modulated tinnitus to…
- Conditions
- Tinnitus, Hearing Disorders, Ear Diseases, Otorhinolaryngologic Diseases
- Trial name
- TinniNap (NCT05467059)
- Testing
- Napping
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Robin Guillard EIRL
Ototoxicity
SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity
The primary objective of this study is to determine the safety and efficacy of SPI-1005 treatment in CF patients with active pulmonary exacerbation that are receiving an IV course of tobramycin, determined by comparing hearing…
- Trial name
- NCT02819856
- Testing
- SPI-1005 Ebselen 200mg Capsule x1, SPI-1005 Ebselen 200mg Capsule x2, SPI-1005 Ebselen 200mg Capsule x3
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Treatment of Symptomatic Lateral Sinus Stenosis, Treatment of Pulsatile Tinnitus Due tu Sinus Stenosis
SiREX-Stent for the Treatment of SymptOmatic Lateral VEnous Sinus Stenosis
The purpose of the study is to assess the efficacy, safety and the clinical benefit of the SiREX stent for the treatment of disabling pulsatile tinnitus due to stenosis of lateral sinus.
- Trial name
- RESOLVE (NCT06726928)
- Testing
- Sinus Stenting
- Where
- France
- Volunteers
- 78 people
- Sponsor
- Acandis GmbH
Tinnitus
AM-101 in the Treatment of Acute Tinnitus 2
The purpose of this research study is to test the safety and effectiveness of the study drug, AM-101. AM-101 is tested for the treatment of tinnitus that started as the result of an injury to the inner ear or due to middle ear…
- Trial name
- TACTT2 (NCT01803646)
- Testing
- AM-101
- Where
- United States
- Volunteers
- 343 people
- Sponsor
- Auris Medical, Inc.
Subjective Tinnitus
Efficacy, Safety and Tolerability of Neramexane in Comparison to Placebo in Patients With Subjective Tinnitus
The purpose of this study is to investigate the safety and efficacy of neramexane mesylate in the treatment of subjective tinnitus in comparison to placebo.
- Trial name
- NCT00772980
- Testing
- Neramexane mesylate
- Where
- 56 sites in Belgium, Czechia and 4 more
- Volunteers
- 400 people
- Sponsor
- Merz Pharmaceuticals GmbH
Tinnitus
Deep TMS of the Left Auditory Cortex Using the HMCIPCC Coil, in the Treatment of Patients With Tinnitus.
The study is a double-blind study designed to evaluate the efficacy of deep transcranial magnetic stimulation (deep TMS) of the left auditory cortex using the HMCIPCC coil, in the treatment of patients with tinnitus
- Trial name
- NCT02053961
- Testing
- Deep Transcranial Magnetic Stimulation
- Where
- Israel
- Sponsor
- Brainsway
Tinnitus
Effect of the Erchonia® HLS™ for the Relief of Tinnitus Symptoms
This study is to see if applying red low-level laser light can help to reduce tinnitus symptoms
- Trial name
- NCT05091060
- Testing
- Erchonia HLS
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Erchonia Corporation
Sensorineural Hearing Loss, Tinnitus
Effect of a Totally Implantable Cochlear Implant on Tinnitus Severity in Adults With Preoperative Tinnitus
The purpose of this study is to investigate the degree of benefit to tinnitus symptoms by using a Totally Implantable cochlear implant (TICI) in a group of patients who have moderate-to-severe tinnitus pre-operatively.
- Trial name
- EXCITE (NCT07893860)
- Testing
- Cochlear implant
- Where
- Spain
- Volunteers
- 14 people
- Sponsor
- Cochlear
Tinnitus, Subjective
Safety and Efficacy of Acupressure Applied Through ForgTin© in Patients With Tinnitus
The main objective of this clinical trial is to evaluate the effectiveness and safety of the medical product ForgTin with regard to the impairment and change in the sensation of tinnitus (volume, frequency, psychological stress).
- Trial name
- NCT04623957
- Testing
- ForgTin©
- Volunteers
- 35 people
- Sponsor
- Pansatori GmbH
Tinnitus
The Effects of Compensatory Auditory Stimulation and Transcranial Direct Current Stimulation on Tinnitus Perception
This study evaluates the ability of compensatory auditory stimulation (CAS) and transcranial direct current stimulation (tDCS) to help alleviate tinnitus.
- Trial name
- NCT02648542
- Testing
- Compensatory auditory stimulation, transcranial direct current stimulation, Combined CAS and tDCS
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Soterix Medical
Tinnitus, Hearing Loss, Bilateral or Unilateral
Evaluating How a Tinnitus Implant Affects Tinnitus Loudness in Adults With Chronic Tinnitus and Varying Levels of Hearing Loss
This study will test an experimental Tinnitus Implant System that consists of a cochlear implant, sound processor and programming software.
- Conditions
- Tinnitus, Hearing Loss, Bilateral or Unilateral, Normal Hearing
- Trial name
- TINIS (NCT06641999)
- Testing
- Tinnitus Implant System
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 16 people
- Sponsor
- Cochlear
Tinnitus
Vagus Nerve Stimulation (VNS) Paired With Tones for Tinnitus
Assess the safety and efficacy of VNS paired with tones for tinnitus using a randomized, controlled, parallel study design.
- Trial name
- NCT01962558
- Testing
- VNS Treatment, VNS Control
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- MicroTransponder Inc.
Tinnitus
Safety Study for NST-001 and the Neuroject Injection Set to Treat Tinnitus
This research study involves an experimental drug (NST_001) and a delivery system. The main purpose of this research study is to investigate the safety of NST-001, delivered directly to the inner ear for the treatment of tinnitus.
- Trial name
- NCT00957788
- Testing
- NST-001
- Where
- 2 sites in Belgium, France
- Volunteers
- 8 people
- Sponsor
- NeuroSystec Corporation
Meniere's Disease
Study to Evaluate SPI-1005 in Adults With Meniere's Disease
This study will evaluate the safety and efficacy of three dose levels of SPI-1005 compared to placebo on vertigo, tinnitus and sensorineural hearing loss in 40 adults with Meniere's disease.
- Trial name
- NCT02603081
- Testing
- SPI-1005
- Where
- 5 sites in United States
- Volunteers
- 40 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Tinnitus
1 Tinnitus Alleviation Via Sensory Substitution
This is a novel experimental device 'MuteButton' can affect the awareness of tinnitus. Sound that arrives at the ears naturally will be presented in the form of touch patterns on the tongue.
- Trial name
- NCT02570048
- Testing
- Mutebutton intervention
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- MuteButton