Clinical trials: Tinnitus
Tinnitus
Evaluation of the OtoBand as a Treatment to Reduce the Perceived Loudness of Tinnitus
This proposed study is a blinded study in which the participant will wear the OtoBand when their tinnitus is present to determine if the OtoBand reduces the perceived loudness of their tinnitus.
- Trial name
- NCT04787653
- Testing
- Otoband
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Otolith Labs
Amyotrophic Lateral Sclerosis (ALS), Angina, Stable
Quest to Analyze One Thousand Humans Meditating
This study will be focused on assessing the molecular, physiological, and emotional correlates of an intensive meditation experience in the context of a retreat setting in a large 2000 plus-person cohort comprised of healthy and…
- Conditions
- Amyotrophic Lateral Sclerosis (ALS), Angina, Stable, Anxiety, Asthma
- Trial name
- QUANTUM (NCT06583395)
- Testing
- Advanced multi-component meditation practice
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Tobias Moeller-Bertram
Tinnitus, Tinnitus, Subjective
Noninvasive Therapy for Tinnitus
The goal of this interventional clinical study is to establish mild therapeutic hypothermia, delivered non-invasively to the structures of the inner ear, as a safe and repeatable therapeutic method for symptomatic relief of…
- Trial name
- NCT07071480
- Testing
- Cold pack-delivered mild therapeutic hypothermia
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Restorear Devices LLC
Chronic Subjective Tinnitus
Study of BGG492 in Patients With Chronic Subjective Tinnitus
This study will assess the efficacy of a two week treatment with BGG492 in patients with chronic subjective Tinnitus.
- Trial name
- NCT01302873
- Testing
- BGG492A
- Where
- 4 sites in Germany, Netherlands
- Volunteers
- 96 people
- Sponsor
- Novartis Pharmaceuticals
Lung Cancer, Head and Neck Cancer
SPI-1005 for Prevention and Treatment of Chemotherapy Induced Hearing Loss
Chemotherapy treatment with platinum based agents is well noted to cause ototoxicity. It is the objective of this study to determine the safety and efficacy of SPI-1005 at three dose levels when delivered orally twice daily for 3…
- Conditions
- Lung Cancer, Head and Neck Cancer, Hearing Loss, Ototoxicity
- Trial name
- NCT01451853
- Testing
- SPI-1005 Low Dose, SPI-1005 Middle Dose, SPI-1005 High Dose
- Where
- United States
- Sponsor
- Sound Pharmaceuticals, Incorporated
Tinnitus
Vardenafil in Tinnitus
There is incidental evidence (casuistic findings) that the treatment with vardenafil of male patients suffering from erectile dysfunction and comorbid tinnitus experienced an improvement of their tinnitus.
- Trial name
- NCT00666809
- Testing
- Levitra (Vardenafil, BAY38-9456)
- Where
- Germany
- Volunteers
- 43 people
- Sponsor
- Bayer
Meniere Disease, Ménière
SPI-1005 for the Treatment of Meniere's Disease
The study is a randomized, double-blind, placebo-controlled, multi-center clinical trial (RCT) with open-label extension study (OLE), of SPI-1005 in adult subjects with definite Meniere's disease with active symptoms within three…
- Trial name
- STOPMD-3 (NCT04677972)
- Testing
- Ebselen
- Where
- 12 sites in United States
- Volunteers
- 220 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Tinnitus
Exploring the Links Between Hearing, Cognition and Brain Activity in People With Tinnitus
The goal of this observational study is to understand the mechanisms underlying tinnitus, and improve the clinical assessment strategies needed to develop targeted therapeutic interventions by comparing endogenous attention…
- Trial name
- GHOSTTONE (NCT06940726)
- Testing
- Quality of Life questionnaires, Hearing tests, Auditory prediction task
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Tinnitus, Hearing Loss
Neuro-feedback Therapy for Treating Tinnitus
Neuro-feedback for treating tinnitus seem to be a promising approach to help people suffering from chronic tinnitus. The past studies on this approach suffered interindividual variability in their results.
- Trial name
- TNTA (NCT03773926)
- Testing
- Neuro-feedback therapy
- Where
- 2 sites in France
- Volunteers
- 30 people
- Sponsor
- Zeta Technologies
Tinnitus
AM-101 in the Treatment of Post-Acute Tinnitus 2
The purpose of this research study is to test the safety and local tolerance of repeated treatment with AM-101.
- Trial name
- AMPACT2 (NCT02040207)
- Testing
- AM-101
- Where
- Germany
- Volunteers
- 487 people
- Sponsor
- Auris Medical AG
Tinnitus
Study of Application of Transcutaneous Trigeminal Nerve Stimulation and Sound Fusion Stimulation on Tinnitus
This study aims to evaluate the efficacy of applying transcutaneous trigeminal nerve stimulation (NUEYNE-T30, NUEYNE-T100) and sound fusion stimulation on tinnitus.
- Trial name
- NCT05291078
- Testing
- A transcutaneous trigeminal nerve stimulator: High Frequency, A transcutaneous trigeminal nerve stimulator: Low Frequency, Sound Therapy
- Where
- South Korea
- Volunteers
- 25 people
- Sponsor
- Nu Eyne Co., Ltd.
Subjective Tinnitus
Efficacy, Safety and Tolerability of Neramexane in Patients With Subjective Tinnitus
The purpose of this study is to investigate the safety and efficacy of neramexane mesylate in the treatment of subjective tinnitus in comparison to placebo.
- Trial name
- EASE (NCT00739635)
- Testing
- Neramexane mesylate
- Where
- 54 sites in Austria, Germany and 3 more
- Volunteers
- 411 people
- Sponsor
- Merz Pharmaceuticals GmbH
Severe Tinnitus
Proof-of-Concept Study Assessing VNS Paired With Tones for Tinnitus
This is a proof-of-concept study designed to provide feasibility information on the clinical use of vagus nerve stimulation (VNS) paired with tones for the treatment of severe tinnitus.
- Trial name
- NCT01253616
- Testing
- vagus nerve stimulation (VNS)
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- MicroTransponder Inc.
Menière's Disease
Latanoprost for the Treatment of Menière's Disease
The purpose of the study is to evaluate the dose regimen, efficacy and safety of latanoprost for the treatment of Menière's disease.
- Trial name
- NCT01973114
- Testing
- Latanoprost
- Where
- 12 sites in Sweden
- Volunteers
- 100 people
- Sponsor
- Synphora AB
Tinnitus
Tinnitus Measured by MEG and Synchronous Neural Interaction™ Test: Template Development
The study is designed to identify specific patterns of brain functional activity associated with chronic, moderate to severe tinnitus through the use of resting-state MEG scans.
- Trial name
- NCT01185990
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Orasi Medical, Inc.
Tinnitus
Bimodal Stimulation Using Auditory and Vibrotactile Stimuli for the Mitigation of Tinnitus
The goal of this clinical trial is to learn if a bimodal stimulation device that combines auditory tones with vibrotactile stimulation to the wrist works to treat moderate to severe tinnitus in adults.
- Trial name
- NCT06508060
- Testing
- Neosensory Wristband, Tones only
- Volunteers
- 200 people
- Sponsor
- Neosensory
Tinnitus, Subjective, Tinnitus, Bilateral
Tinnitus Patient Preferences Survey
The goal of this survey is to assess several aspects related to patient preferences regarding interventions for alleviating tinnitus through invasive electrical brain stimulation (neuromodulation).
- Conditions
- Tinnitus, Subjective, Tinnitus, Bilateral, Tinnitus, Noise Induced, Tinnitus, Hearing Loss, Cochlear Implant Users
- Trial name
- NCT06782308
- Testing
- Survey using a questionnaire.
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Nicolas Gninenko
Meniere's Disease
OTO-104 for Meniere's Disease
The purpose of this study is to evaluate the safety of OTO-104 in subjects with unilateral Meniere's disease. The effectiveness of OTO-104 to reduce the symptoms of Meniere's disease will also be evaluated.
- Trial name
- NCT01084525
- Testing
- OTO-104 (steroid) 3 mg, OTO-104 (steroid) 12 mg
- Where
- 15 sites in United States
- Volunteers
- 44 people
- Sponsor
- Otonomy, Inc.
Tinnitus
Vestipitant Or Vestipitant/Paroxetine Combination In Subjects With Tinnitus And Hearing Loss.
Tinnitus associated to hearing loss is a high prevalent audiologic disorder with important unmet needs as far as therapy is concerned.
- Trial name
- NCT00394056
- Testing
- Vestipitant, Vestipitant + Paroxetine
- Where
- United Kingdom
- Volunteers
- 26 people
- Sponsor
- GlaxoSmithKline
Meniere's Disease, Ménière's Disease
SPI-1005 for the Treatment of Meniere's Disease (Open Label)
Study of the safety of open-label SPI-1005 400 mg BID treatment in adults with Meniere's Disease (MD) for 6 or 12 months to support chronic or chronic intermittent use.
- Trial name
- NCT06859788
- Testing
- Ebselen
- Where
- 9 sites in United States
- Volunteers
- 200 people
- Sponsor
- Sound Pharmaceuticals, Incorporated