Clinical trials: Tissue Adhesion
Fallopian Tube Adhesion
Effect of Shockwaves on Fallopian Tubes Adhesion
The purpose of this study is to determine the effect of shock waves on fallopian tube adhesions.
- Trial name
- NCT06755528
- Testing
- Chitosan, shockwave therapy
- Volunteers
- 40 people
- Sponsor
- Cairo University
End-Stage Kidney Disease (ESKD), Hemodialysis
Cardiovascular and Bone Mineral Markers in Dialysis Patients and Healthy Controls
This observational study will compare cardiovascular status, bone mineral metabolism, systemic inflammation, body composition, functional status, quality of life, pruritus, and pain among patients receiving different renal…
- Conditions
- End-Stage Kidney Disease (ESKD), Hemodialysis, Peritoneal Dialysis (PD)
- Trial name
- NCT07686978
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Gazi University
Safety and Tolerability in Healthy Volunteers
Discrete(TM) Safety Clinical Trial GLAD-01
This study will assess the safety and tolerability of a new liquid anti-adhesion device, Discrete(TM), in healthy volunteers, in order to determine the best volume of Discrete(TM) to go forward into clinical efficacy research.
- Trial name
- NCT04034784
- Testing
- Discrete(TM), Control Lactated Ringer's Solution (Control LRS)
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- ARC Medical Inc.
Thyroid Nodule, Thyroid Cancer
Effect of Anti-adhesion Barrier on the Voice Quality After Thyroidectomy.
To determine whether the use of anti-adhesion barrier after thyroid surgery can prevent the voice changes after surgery, using objective voice-related indicators.
- Conditions
- Thyroid Nodule, Thyroid Cancer, Voice Disorders
- Trial name
- NCT04853680
- Testing
- Anti-adhesion barrier (Collarbarrier)
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Inha University Hospital
Thalassemia, Sickle Cell Disease
Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation
Allogeneic blood and marrow transplantation remains the only viable cure for children who suffer from many serious non-malignant hematological diseases. Transplantation, however, carries a high risk of fatal complications.
- Conditions
- Thalassemia, Sickle Cell Disease, Glanzmann Thrombasthenia, Wiskott-Aldrich Syndrome
- Trial name
- NCT01319851
- Testing
- Alefacept
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Emory University
Small Bowel Adhesion, Small Bowel Obstruction
Low-osmolar Water Soluble Contrast Agent in Management of Adhesive Small Bowel Obstruction
Adhesive small bowel obstruction (ASBO) is a condition that is commonly found in patients with history of abdominal surgery. The management for such condition can be controversial.
- Trial name
- NCT06140173
- Testing
- Low osmolar contrast, Sterile water
- Volunteers
- 66 people
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Myoma;Uterus
Prevalence of Intrauterine Adhesions After Myomectomy
This prospective, multicenter, observational study evaluated the prevalence of intrauterine adhesions after laparoscopic or laparotomic myomectomy and investigated clinical and surgical factors associated with their occurrence.
- Trial name
- NCT04030273
- Testing
- Diagnostic hysteroscopy
- Where
- Italy
- Volunteers
- 62 people
- Sponsor
- Università degli Studi dell'Insubria
Non-carious Cervical Lesions
Deproteinization as a Coadjuvant in Dentin Adhesion of Noncarious Cervical Lesions
This study will verify the effect of the application of a substance (10% sodium hypoclorite -NaOCL) in dentin on noncarious cervical lesions, with the aim of increasing the longevity of the restorations performed in this type of…
- Trial name
- NCT03086720
- Testing
- Sodium hypochlorite, Water
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Skin (FLACC Scores of Test Subjects) After Tape Removal
Assessment of Wound Care Product Skin Adhesion
The purpose of this exploratory study is to assess the adhesive forces to skin of samples over the period of 24 hours to establish the peel-off measurement method at the Essity study site.
- Trial name
- SWAP (NCT07136870)
- Testing
- Medical tape
- Where
- Sweden
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Essity Hygiene and Health AB
Endometriosis, Adhesion
New Cross Linked Hyaluronan Gel After Deep Infiltrating Endometriosis Surgery
Hyaluronan, a glycosaminoglycan found in connective tissues and extracellular matrix, has been postulated to reduce postoperative adhesions, because of its unconditioned biological functions at tissue repair but unfortunately it…
- Conditions
- Endometriosis, Adhesion, Quality of Life, Surgery
- Trial name
- HYALOENDOQoL (NCT04023383)
- Testing
- 40 cc HyaRegen NCH gel, 40 cc sterile saline solution
- Volunteers
- 60 people
- Sponsor
- Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Caries Class II
Clinical Performance of Injection-Molding Vs. Incremental Packing of Resin Composite in Cavitated Posterior Teeth
The clinical performance of 2 bonding and composite packing techniques in the proximal cavities of permanent posterior teeth will be assessed.
- Trial name
- NCT05020093
- Testing
- Injection molding, Incremental packing
- Where
- Egypt
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Cairo University
Adhesion Properties of Wound Care Devices
Evaluation of Adhesion Properties in Wound Care Devices
Molnlycke manufactures and markets self-adhesive wound care devices intended to protect various types of wounds during treatment.
- Trial name
- NCT06392165
- Testing
- self-adhesive device
- Where
- Sweden
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Molnlycke Health Care AB
Myoma
Safety and Efficacy Study of a Hydrogel, Applied Following Removal of Myomas During Gynecologic Surgery, Administered for the Prevention/Reduction of Postoperative Adhesion Formation
The purpose of this study was to determine whether the adhesion prevention gel was safe to use, and was effective for the prevention/reduction of adhesion formation that typically occurs following gynecological surgery to remove…
- Trial name
- NCT00562471
- Testing
- Adhibit Adhesion Prevention Gel, Standard of Care Comparator
- Where
- 6 sites in Canada, Germany and 1 more
- Volunteers
- 76 people
- Sponsor
- Angiotech Pharmaceuticals
Healthy
Bioequivalence of Two Transdermal Clonidine Administrations in Healthy Volunteers
To establish the bioequivalence and adhesion properties of transdermal clonidine prepared with Oppanol® brands of polyisobutylene (PIB) vs.
- Trial name
- NCT02096744
- Testing
- Catapres-TTS-1, Intervention 1: Catapres-TTS-3, Intervention 2: Catapres-TTS-3
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Lumbar Spinal Stenosis, Lumbar Disc Herniation
Efficacy and Safety of Ionized Atelocollagen Adhesion Barrier (Collabarrier®) in Spine Surgery
This multicenter, randomized, subject- and evaluator-blinded, active-controlled, non-inferiority clinical trial was conducted to evaluate the efficacy and safety of Collabarrier®, a collagen-based adhesion barrier, compared to…
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Epidural Fibrosis, Postoperative Adhesion
- Trial name
- NCT07153822
- Testing
- Collagen-based adhesion barrier, Sodium hyaluronate(HA) and Sodium Carboxymethylcellulose(CMC)-based adhesion barrier
- Where
- 6 sites in South Korea
- Volunteers
- 69 people
- Sponsor
- DALIM TISSEN Co., Ltd.
Intrauterine Adhesion
The Efficacy and Safety of Disposable Balloon Uterine Stent in Patients With Asherman Syndrome
Asherman's syndrome is characterized by the presence of intrauterine adhesions (IUA) as well as symptoms such as amenorrhea, hypomenorrhea, pelvic pain, and infertility.
- Trial name
- NCT03330873
- Testing
- disposable balloon uterine stent, Foley catheter
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Obstetrics and Gynecology Hospital
Adhesions
Adhesions After Open Versus Laparoscopic Resection of Colorectal Malignancies Detected During Liver Resection
Rationale: Adhesion formation is a frequent complication after abdominal surgery. Adhesion formation might be reduced by laparoscopic surgery, however sound evidence is lacking.
- Trial name
- ALIVE (NCT01720966)
- Testing
- Liver resection
- Where
- 6 sites in Netherlands
- Volunteers
- 150 people
- Sponsor
- Radboud University Medical Center
Infertility, Male
Reproductive Outcome After Sperm Selection for Intracytoplasmic Sperm Injection (ICSI) Using Zona Pellucida Proteins
The aim of this study is to analyze the effect of a sperm selection method by adhesion to partners' zona pellucida proteins on the assisted reproduction treatment (ART) outcome parameters.
- Trial name
- NCT05161247
- Testing
- Zona pellucida sperm selection, Conventional sperm selection, Intracytoplasmic Sperm Injection (ICSI)
- Where
- Bulgaria
- Volunteers
- 368 people
- Sponsor
- Nadezhda Women's Health Hospital
Infertility, Female, Intrauterine Adhesion
HMG Stimulation Versus HRT for Endometrial Preparation Prior to Blastocyst Transfer in Moderate to Severe IUA Patients
Evaluation of endometrial preparation using either human menopausal gonadotrophin (HMG) stimulation and hormone replacement therapy (HRT) prior to blastocyst transfer in patients with moderate to severe intrauterine adhesion…
- Trial name
- NCT03578172
- Testing
- human menopausal gonadotrophin, hormone replacement therapy
- Where
- China
- Volunteers
- 186 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Adhesions, Abdominal Cavity
A-Part® Gel as Adhesion Prophylaxis After Major Abdominal Surgery Versus a Non-treated Group
The safety of applying A-Part® Gel intra-peritoneally under the incision in order to prevent post-surgical adhesions after median laparotomy.
- Trial name
- A-PART (NCT00646412)
- Testing
- A-Part® Gel
- Where
- Germany
- Volunteers
- 60 people
- Sponsor
- Aesculap AG