Clinical trials: Tissue Injury
Mastectomy
Brijjit® for Wound Closure in Gender Affirming Mastectomies
This study will evaluate the use of Brijjit® for wound closure in individuals undergoing bilateral double incision gender affirming mastectomies with a single surgeon (Rachel Bluebond-Langner, MD).
- Trial name
- NCT05368519
- Testing
- Brijjit®
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- NYU Langone Health
Stress Disorders, Post-Traumatic, Tissue Donors
Evaluation of Post-traumatic Stress Among the Nearest Relatives of Brain-dead Organ Donors
The goal is to compare post tramautic stress between the nearest relatives of brain-dead patients who are organ donor to those of brain-dead patients who are not organ donors for medical, legal or opposition reasons.
- Conditions
- Stress Disorders, Post-Traumatic, Tissue Donors, Tissue and Organ Procurement
- Trial name
- NCT01214018
- Testing
- Questionnaires and interview
- Where
- 4 sites in France
- Volunteers
- 91 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Diabetic Foot
Using mHealth to Modernize Diabetes Care
In this study the investigators are testing a device that may help us tell how well the participants' wound is healing. This device is called the MIMOSA, and it shines different "colours" of light on the participants' skin.
- Trial name
- MDM (NCT03516474)
- Testing
- MIMOSA Diagnostics
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Brain Injury, Dementia
Neuropsychiatric Evaluation of Healthy Volunteers and Adults With Schizophrenia
The purpose of this study is to evaluate the cognitive processes of participants with schizophrenia, participants with nervous system and mental disorders, and healthy volunteers.
- Conditions
- Brain Injury, Dementia, Healthy, Mental Disorder
- Trial name
- NCT00001323
- Where
- United States
- Volunteers
- 810 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Ankle Disease, Ankle Injuries
Perineural Dexamethasone on the Duration of Popliteal Nerve Block for Anesthesia After Pediatric Ankle Surgery
Effect of Perineural Dexamethasone on the duration of popliteal nerve block for Anesthesia After Pediatric ankle/foot surgery.
- Conditions
- Ankle Disease, Ankle Injuries, Foot Injury, Foot Diseases
- Trial name
- NCT06086418
- Testing
- 0.9 % Sodium Chloride, 0.1mg/kg Dexamethasone, 0.05mg/kg Dexamethasone
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Poznan University of Medical Sciences
Breast Cancer, Radiation Fibrosis
Autologous Fat Grafting in Radiated Soft Tissue Reconstruction
The purpose of this study is to observe the effect of autologous fat grafting on soft tissue reconstruction of the breast following radiation treatment.
- Conditions
- Breast Cancer, Radiation Fibrosis, Fat Grafting
- Trial name
- NCT05890196
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Chicago
Non-small Cell Lung Cancer, Esophageal Cancer
Radiation-induced Toxicity of the Heart
Late side effects in radio(chemo)therapy [R(CH)T] pose a critical limitation to patients' overall survival and quality of life. Even though toxicities of the heart are highly relevant for patients with cancer in the thoracic…
- Conditions
- Non-small Cell Lung Cancer, Esophageal Cancer, Breast Cancer Female
- Trial name
- CorTox (NCT06986291)
- Testing
- Imaging and biomarkers
- Where
- Germany
- Volunteers
- 325 people
- Sponsor
- Technische Universität Dresden
Breast Cancer
Assessment of Cardiotoxicity After Chemotherapy for Breast Cancer by Cardio-vascular Magnetic Resonance (MR)
Consecutive patients with a first diagnosis of breast cancer will be identified at the Tom Baker Cancer Centre (TBCC) and included into the study, if they are going to receive chemotherapy with anthracyclines and / or Trastuzumab…
- Trial name
- Cardiotox (NCT00679874)
- Testing
- Cardio-vascular MRI
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- University of Calgary
Radiodermatitis, Breast Neoplasms
Effects of Herbal Products on Reduction of Radiation-induced Dermatitis in Breast Cancer Patients
The herbal products on reduction of radiation-induced dermatitis in patients with breast cancer
- Conditions
- Radiodermatitis, Breast Neoplasms, Adverse Effect of Radiation Therapy
- Trial name
- NCT02922244
- Testing
- Control, Cucumber cream, Centella cream
- Where
- Thailand
- Volunteers
- 150 people
- Sponsor
- Chulabhorn Cancer Center
Pressure Sores
Effect of Negative Wound Pressure on P.S
This study will compare the NPWT using the NPD to the conventional wound dressing and specifically evaluating (i) reduction of wound surface area and depth, (ii) removal of slough and formation of granulation tissue
- Trial name
- NCT06243328
- Testing
- negative wound pressure therapy
- Volunteers
- 40 people
- Sponsor
- Assiut University
Wounds and Injuries
Effect of Regulated Oxygen-Enriched Negative Pressure Therapy (RO-NPT) On Soft Tissue Wound Repair
The investigators believe that regulated oxygen-enriched negative Pressure Therapy (RO-NPT) will be beneficial in the reduction or elimination of anaerobic infection in hard-to-heal soft tissue wounds.
- Trial name
- NCT02357628
- Testing
- Wound treatment with RO-NPT, Wound Irrigation
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Hillel Yaffe Medical Center
Arterial Puncture, Radial Artery Injury
Blood'up Device Versus Manual Palpation for Arterial Puncture in Healthy Volunteers: A Pilot Randomized Study Under Normal and Simulated Hypotension
Arterial puncture is a common procedure in the management of hospitalized patients. It is most often performed at the level of the radial artery and allows arterial blood gas analysis.
- Conditions
- Arterial Puncture, Radial Artery Injury, Hypotension, Healthy
- Trial name
- NCT07765199
- Testing
- Arterial blood gas, Simulated hypotension, Arterial Puncture using Blood'Up device
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Cutibacterium Acnes Contamination
Wound Irrigation Comparative Effectiveness Study
The primary objective of this study is to compare the presence of C acnes in bacteriologic cultures taken from participant samples of subcutaneous and deep tissue prior to deep surgical irrigation using either Normal Saline…
- Trial name
- NCT06379919
- Testing
- Irrisept Irrigation, Saline Irrigation Solution Delivery
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Orthopaedic Education and Research Institute (dba Hoag Orthopedics)
Breast Cancer, Cardiotoxicity
Exercise Prescription Guided by Heart Rate Variability in Breast Cancer Patients
Breast cancer is a chronic disease that has seen a boom in research into its treatments, improvements and effects in recent decades.
- Conditions
- Breast Cancer, Cardiotoxicity, Autonomic Imbalance
- Trial name
- NCT05040867
- Testing
- Physical exercise program
- Where
- Spain
- Volunteers
- 90 people
- Sponsor
- GO fit Lab- Ingesport
Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers
Use of Hydroprep Wound Therapy With Motion Negative Pressure Therapy for Treatment of Chronic Lower Extremity Wounds
Use of a motorized waterjet to debride wounds to improve healing outcomes.
- Conditions
- Chronic Lower Leg Ulcer, Diabetic Lower Extremity Ulcers, Pressure Injuries, Traumatic Wounds and Injuries
- Trial name
- NCT07653165
- Testing
- Motion NPWT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- West Boca Center for Wound Healing
Prevention
Evaluation of the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer Patients
the purpose of this study is to evaluate the Effect of Alpha Lipoic Acid on Radiation Induced Dermatitis in Breast Cancer Patients
- Trial name
- NCT07256119
- Testing
- Alpha Lipoic Acid
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Ain Shams University
Venous Insufficiency (Chronic)(Peripheral), Venous Reflux
Adrenaline Reduces Ecchymoses and Hematomas and Improves Quality of Life After Classic Saphenous Vein Stripping
Aim of the present study is to investigate the efficiency of adrenaline (epinephrine) used locally in reducing and avoiding post-operative formation of subcutaneous ecchymoses and hematomas, in comparison with traditional…
- Conditions
- Venous Insufficiency (Chronic)(Peripheral), Venous Reflux, Venous Insufficiency of Leg, Venous Stasis
- Trial name
- ARESQOLSAVES (NCT04758728)
- Testing
- Great saphenous vein stripping and varicectomies, Epinephrine Topical, normal saline
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Junior Doctors Network-Hellas
Pressure Ulcer
Effectiveness of Aurix Therapy in Pressure Ulcers
The aim of this trial is to demonstrate the effectiveness of complete wound healing in a prospective, open-label, randomized trial in which pressure ulcers will be treated using Aurix and standard care and compared 1:1 to…
- Trial name
- NCT02352467
- Testing
- Aurix
- Where
- 22 sites in United States
- Volunteers
- 800 people
- Sponsor
- Nuo Therapeutics
Dermatitis, Radiation Induced
Efficacy of Pulsed Electromagnetic Field Therapy on Acute Radiodermatitis in Breast Cancer Patients
This study aims to evaluate the impact of PEMF on acute radiodermatitis in breast cancer patient and post mastectomy patients.
- Trial name
- NCT06003764
- Testing
- Pulsed electromagnetic field, traditional skin care
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ahram Canadian University
Breast Cancer, Cardiac Toxicity
BreAst Cancer and Cardiotoxicity Induced by RAdioTherapy: the BACCARAT Study
Breast radiotherapy RT used until the 1990s was clearly responsible for increased mortality due to long term cardiac complications.
- Trial name
- BACCARAT (NCT02605512)
- Testing
- Subclinical cardiac lesions and biomarkers
- Where
- France
- Volunteers
- 118 people
- Sponsor
- Sophie JACOB