Clinical trials: Tobacco
Tobacco Use, Tobacco Cessation
A Brief Digital Screening Tool to Address Tobacco and E-cigarette Use in Pediatric Medical Care
Tobacco use is the single greatest preventable cause of morbidity and mortality in Canada, accounting for 48,000 deaths and $16.2 billion annually in attributable health-related costs.
- Conditions
- Tobacco Use, Tobacco Cessation, Second Hand Tobacco Smoke, Smoking, Tobacco
- Trial name
- CanCEASE (NCT05366790)
- Testing
- CEASE and CEASE-A
- Where
- Canada
- Volunteers
- 130 people
- Sponsor
- St. Justine's Hospital
Smoking Cessation, Smoking Reduction
Tobacco Cessation in Public Housing
The inequity in cessation resources is at forefront in the recently enacted nationwide smoking ban in public housing facilities.
- Conditions
- Smoking Cessation, Smoking Reduction, Smoking, Tobacco
- Trial name
- NCT04889638
- Testing
- Cessation Intervention
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cigarette Smoking
Interactive Voice Response Technology to Mobilize Contingency Management for Smoking Cessation
Cigarette smoking remains the most common source of preventable morbidity and mortality in the United States, with in excess of $167 billion in economic costs per year.
- Trial name
- NCT01484717
- Testing
- contingency management for smoking abstinence, transdermal nicotine, Telephone counseling
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- UConn Health
Electronic Cigarette Use
Use Behavior, Nicotine Uptake, and Subjective Effects Comparison of Tobacco and Menthol e-Liquids by ENDS Consumers
This study is being conducted to evaluate the impact of within-flavor category (tobacco and menthol) differences in e-liquid flavors on product use behaviors, nicotine uptake, and subjective effects by current ENDS consumers when…
- Trial name
- NCT05134415
- Testing
- RELX ENDS Tobacco Flavor 1, RELX ENDS Tobacco Flavor 2, RELX ENDS Menthol Flavor 1
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cheerain HK Limited
Cigarette Smoking, Nicotine Dependence
Evaluation of Low and High Nicotine Tobacco Free Nicotine Pouches
Tobacco-free oral nicotine pouches (such as Zyn brand) are a less harmful alternative to cigarette smoking. Pouches, however, contain nicotine, and addictive substance that is not risk-free.
- Conditions
- Cigarette Smoking, Nicotine Dependence, Smoking Cessation
- Trial name
- Pack2Pouch (NCT06678789)
- Testing
- High Nicotine Dose, Low Nicotine Dose
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Smoking, Nicotine
Impact of Daridorexant on Sleep, Daytime Alertness, and Smoking
Tobacco use is the leading cause of preventable death in the U.S., with 480,000 deaths per year and 7.7 million deaths globally.
- Conditions
- Smoking, Nicotine, Tobacco, Addiction
- Trial name
- NCT07328594
- Testing
- Daridorexant 50 mg
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Legacy Health System
Tobacco Use Cessation
Study of the Effectiveness of a Virtual Reality Treatment in the Management of Smoking Cessation
Tobacco is an addiction with serious consequences: somatic, psychiatric... The number of requests for treatment for tobacco addiction is gradually increasing from year to year, but conventional treatments have limited…
- Trial name
- 3DSmoke (NCT04610931)
- Testing
- Virtual Reality-Enhanced Cognitive Behavioral Therapy (VR-CBT), cognitive behavior therapy
- Where
- France
- Volunteers
- 74 people
- Sponsor
- University Hospital, Clermont-Ferrand
Electronic Cigarette Use
Effect of Menthol on ENDS Users' Addiction and Exposure
The use of electronic nicotine delivery systems (ENDS; e-cigarettes) has reached epidemic levels among young people in the United States (US).
- Trial name
- NCT05338801
- Testing
- Menthol-flavored e-cigarette, Tobacco-flavored e-cigarette
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Florida International University
Smoking
Proactive Outreach for Smokers in VA Mental Health
Veterans with a mental health diagnosis have higher a prevalence of smoking and higher rates of smoking-related morbidities compared to the general Veteran population.
- Trial name
- PROMH (NCT01737281)
- Testing
- Proactive outreach, Usual care
- Where
- 4 sites in United States
- Volunteers
- 1,938 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Smokeless Tobacco Use
Highdose Nicotine Patch Therapy for Smokeless Tobacco Use
Smokeless tobacco use ("chewing") is associated with negative health effects. To date, no medications have been shown to help chewers quit long-term.
- Trial name
- NCT00939029
- Testing
- nicotine replacement therapy (nicotine patches)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Nicotine Dependence
Maintaining Nonsmoking
The research is based on a chronic disorder model of cigarette smoking which suggests that long-term treatment targeted to prevent relapse may be useful.
- Trial name
- NCT01162239
- Testing
- Varenicline, Initial Individual counseling, Check-ins with medical staff
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Smoking Tobacco
Tobacco Cessation Intervention
This study is planned as an evaluation of a low cost, simple smoking cessation intervention. There is very little information about the effectiveness of a simple tobacco cessation strategy.
- Trial name
- NCT03657511
- Testing
- Educational Interventions to Promote Tobacco Cessation
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Barbara Ann Karmanos Cancer Institute
Nicotine Dependence, Cigarettes, With Withdrawal
A Dietary Supplement for Early Cigarette Withdrawal
The purpose of this study is to determine whether a dietary supplement (DS) is effective in protecting against sad mood during early cigarette withdrawal.
- Trial name
- CIGAR (NCT02042521)
- Testing
- Dietary Supplement
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Centre for Addiction and Mental Health
Nicotine Use Disorder
Pharmacokinetics and Acute Effects of Multiple Dose of Nicotine: Electronic Cigarette and Cigarette
The purposes of this study are 1) to determine the pharmacokinetics of nicotine after multiple dose administration by electronic cigarette and 2) to compare the acute effects of multiple dose of nicotine administrated by…
- Trial name
- NCT02511704
- Testing
- Nicotine
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Parc de Salut Mar
Heart Rate Variability, Biofeedback, Nicotine Dependence, Nicotine Withdrawal, Anxiety, Depression, Insomnia
Effects of HRV Biofeedback on Autonomic Function and Nicotine Withdrawal Symptoms and Dependence in Smoking Cessation Adults
This study is a randomized controlled trial. It is estimated that 80 quitters will be recruited, and they will be randomly included in the experimental group and 40 in the control group.
- Trial name
- NCT04679636
- Testing
- heart rate variability biofeedback
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- National Defense Medical Center, Taiwan
Tobacco Dependence
Improving Health for Aboriginal People Through Tobacco Related Research
Aim: To identify barriers and facilitators in the uptake of smoking cessation pharmacotherapies, tobacco prevention, doctor visits, smoking amongst youth, community held health priorities and barriers to research in Aboriginal…
- Trial name
- NCT01735448
- Testing
- Focus group, One-on-one interviews, Survey
- Where
- 3 sites in Australia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Queen Elizabeth Hospital
Mental Health Disorder, Substance Abuse Drug
Tobacco Cessation Among Smokers Under Alcohol and/or Cannabis Treatment
Aims: To identify the predictors associated with smoking cessation in smokers under treatment for alcohol and/or cannabis treated in drug treatment centers (DTC).
- Conditions
- Mental Health Disorder, Substance Abuse Drug, Alcohol Abuse, Cannabis Use
- Trial name
- ACT-ATAC (NCT04841655)
- Where
- 2 sites in Spain
- Volunteers
- 1,625 people
- Sponsor
- Institut Català d'Oncologia
Cigarette Smoking
Concurrent Nicotine Patch / Denicotinized Cigarette Therapy for Smoking Cessation II
The main goals of the study are to assess benefits of higher doses of the nicotine patch prior to smoking cessation for high- and low-dependent smokers, and to investigate the potential relationship between genetic factors and…
- Trial name
- CON NIC II (NCT00734617)
- Testing
- Nicotine Patch
- Where
- United States
- Volunteers
- 479 people, healthy volunteers welcome
- Sponsor
- Duke University
Chronic Obstructive Pulmonary Disease
Usefulness of the Chronic Obstructive Pulmonary Disease-population (COPD-PS) Questionnaire and the COPD-6 Device in the Chronic Obstructive Pulmonary Disease Detection in a Tobacco Detoxication Consultation
The aim of this study is to evaluate the usefulness of the chronic obstructive pulmonary disease-population questionnaire (COPD-PS) and the COPD-6 device in the early detection of chronic obstructive pulmonary disease in smoker…
- Trial name
- NCT04121117
- Testing
- Chronic obstructive pulmonary disease screening
- Where
- Spain
- Volunteers
- 245 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Tobacco Smoking, Oxidative Stress
N-acetylcysteine for Tobacco Smoking
The purpose of this study is to investigate the efficacy of N-acetylcysteine (NAC) for smoking cessation in a double blind, randomized, placebo-controlled trial.
- Conditions
- Tobacco Smoking, Oxidative Stress, Inflammation
- Trial name
- NACNOS (NCT02124525)
- Testing
- N-acetylcysteine
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Estadual de Londrina