Clinical trials: Tobacco Abuse
Posttraumatic Stress Disorder, Tobacco Dependence
Tobacco Treatment as Augmentation for Cognitive Processing Therapy for PTSD
The purpose of this study is to examine whether tobacco affects recovery from PTSD. There are 3 goals of the study; (1) to test if quitting tobacco prior to PTSD treatment affects treatment success, (2) to test how PTSD symptoms…
- Trial name
- NCT02012452
- Testing
- Tobacco treatment, Health Education
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Nicotine Dependence
Prevention of Nicotine Abstinence in Critically Ill Patients After Major Surgery
The primary objective of this study is to determine whether the application of transdermal nicotine patches in critically ill patients after major surgery with nicotine abstinence condition is associated with a lower incidence of…
- Trial name
- NCT03847155
- Testing
- Nicotine patch
- Where
- Czechia
- Volunteers
- 52 people
- Sponsor
- University Hospital Ostrava
Nicotine Dependence
Prazosin for Smoking Cessation
The most likely outcome of smoking cessation attempts is relapse, underscoring the need to advance novel treatments. Preclinical research shows that the noradrenergic system is critical for modulating drug-seeking behavior and…
- Trial name
- NCT01642433
- Testing
- Prazosin
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Smoking, Sleep Disturbance
Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal
The number one preventable cause of death in the world is tobacco use. Cigarette smoking in particular, costs an estimated $300 billion due to expenses related to medical care and lost productivity.
- Conditions
- Smoking, Sleep Disturbance, Nicotine Dependence
- Trial name
- NCT03968900
- Testing
- Sleep restriction condition, Sleep extension condition
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Alabama at Birmingham
Tobacco Use Disorder
Smoking Cessation Treatment for Substance Use Dependents
The present research project aims to develop an innovative and empirically validated intervention protocol for smoking cessation among patients with substance use disorders (SUDs).
- Trial name
- NCT03551704
- Testing
- CBT + EFT, CBT + EFT + CM
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- University of Oviedo
Tobacco Use Disorder, Weight Gain
Lorcaserin for Preventing Weight Gain Among Smokers
This will be an open label clinical trial with all subjects receiving both lorcaserin and varenicline with a primary aim of reducing post cessation weight gain.
- Trial name
- NCT02393547
- Testing
- Varenicline, Lorcaserin
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cannabis Use Disorder, Stimulant Use Disorder
Emotional Brain Training for Addiction Medicine Treatment - A Pilot Study
The goal of this clinical trial is to determine whether Emotional Brain Training (EBT), a behavioral modification method, can help manage stress and health problems related to addiction.
- Conditions
- Cannabis Use Disorder, Stimulant Use Disorder, Opioid Use Disorder, Tobacco Use Disorder
- Trial name
- NCT07001371
- Testing
- Emotional Brain Training, Standard addiction counseling and medical therapy
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Loma Linda University
Nicotine Dependence, Opiate Dependence
Developing a Smoking Cessation Intervention for Methadone Maintained Smokers
The purpose of this study is to pilot and evaluate, in a randomized controlled trial, the immediate and long-term effects of a newly developed, tailored, intensive smoking cessation intervention among methadone maintained smokers…
- Trial name
- NCT01393392
- Testing
- Intensive, tailored intervention, NJ Quitline Referral
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Rutgers, The State University of New Jersey
Nicotine Dependence
Lab to Real World Assessment of E-cigarette Abuse Liability and Appeal
The proposed research is a longitudinal human lab study to examine how measures of abuse liability and product appeal vary by e-cigarette device type, and how these lab assessments may predict subsequent e-cigarette and other…
- Trial name
- NCT02520349
- Testing
- MarkTen and e-Go e-cigarettes
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Truth Initiative
Carcinoma, Squamous Cell of Head and Neck, Tobacco Use Disorder
Smoking Tobacco Cessation Integrated Program of Patients Treated for the Head and the Neck Cancer
Head and neck squamous cell carcinomas (HNSCCs) arise in the mucosa of the upper aero-digestive tract. They are the 6th most prevalent type of cancer worldwide.
- Trial name
- INTENT (NCT03788785)
- Testing
- Experimental arm, Control arm
- Where
- 3 sites in France
- Volunteers
- 24 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nicotine Dependence, Tobacco Dependence
ROSCAP: Reduction of Smoking in Cardiac Patients Study
Background. The ROSCAP Study was a randomized controlled trial in heart disease patients to test the effect of a smoking reduction intervention on cigarettes per day (cpd) and biochemical and clinical indicators of tobacco…
- Conditions
- Nicotine Dependence, Tobacco Dependence, Cardiac Disease
- Trial name
- NCT00301626
- Testing
- smoking reduction intervention (including NRT)
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- National Institutes of Health (NIH)
Major Depressive Disorder, Nicotine Dependence
Sequential Use of Fluoxetine for Smokers With Elevated Depressive Symptoms
The primary purpose of this study is to determine whether, among smokers with elevated depressive symptoms, sequential antidepressant pharmacotherapy with fluoxetine (20 mg) begun 8 weeks prior to and extended throughout standard…
- Conditions
- Major Depressive Disorder, Nicotine Dependence, Depression
- Trial name
- NCT00578669
- Testing
- Fluoxetine, Dextrose
- Where
- United States
- Volunteers
- 206 people, healthy volunteers welcome
- Sponsor
- Butler Hospital
Vaping Teens, Vaping Behaviors
Developing an E-Cigarette Cessation Intervention for Hispanic/Latina(o) Youth in Florida: The BReATHE Study
Electronic (e-)cigarettes are the most used nicotine product among U.S. youth. Hispanic/Latino (H/L) youth are at greater risk for e-cigarette use, yet few evidence-based cessation programs exist for youth, and even fewer are…
- Conditions
- Vaping Teens, Vaping Behaviors, Vaping Cessation, Tobacco Use Disorder
- Trial name
- NCT07192601
- Testing
- E-cigarette Cessation Manual
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Florida International University
Nicotine Dependence, Cigarettes
Penn State TXT2Quit Study
This study is evaluating the feasibility and short term smoking cessation outcomes of an automated smoking cessation intervention delivered via mobile phone text messaging as an adjunct to Varenicline in a primary care setting.
- Trial name
- NCT02367391
- Testing
- Motivational Text Messages, Control
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Smoking, Cigarette, Nicotine Dependence
Using ANDS to Reduce Harm for Low SES Cigarette Smokers
This study investigates whether providing 8 weeks of complimentary electronic cigarettes (EC) or nicotine pouches (NP) to low socioeconomic status (SES) adults who smoke and are unable or unwilling to quit smoking will lead to…
- Trial name
- NCT05327439
- Testing
- Nicotine (electronic cigarette), Nicotine (nicotine pouch)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Brown University
Tobacco Use Disorder, Mental Illness
Comparing Two Behavioral Approaches to Quitting Smoking in Mental Health Settings
The study team will conduct a Multisite Randomized Controlled Trial to evaluate the advantages and disadvantages of two approaches for quitting smoking among people with serious mental illness (SMI).
- Conditions
- Tobacco Use Disorder, Mental Illness, Recurring Major Depressive Disorder, Bipolar Disorder
- Trial name
- MTQT (NCT05030272)
- Testing
- Quit on the Go App (formerly "Learn to Quit " App), Brief advice, Nicotine patch
- Where
- 3 sites in United States
- Volunteers
- 343 people
- Sponsor
- Wake Forest University Health Sciences
Lung Cancer Screening, Tobacco Use Disorder
Multilevel Intervention for LDCT Lung Cancer Screening and Smoking Cessation Among African Americans
This study aims to reduce disparities and the burden of lung cancer among African American smokers by supporting a Multiple-level intervention integrating lung cancer screening and smoking cessation (MILS), followed the NIH DEIA…
- Conditions
- Lung Cancer Screening, Tobacco Use Disorder, Smoking Cessation
- Trial name
- NCT07576595
- Testing
- Smoking cessation multilevel Intervention
- Where
- 2 sites in United States
- Volunteers
- 250 people
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans
Cigarette Smoking
Tailored Tobacco Quitline for Rural Veterans
The proposed work is designed to help increase access to tobacco cessation services among rural veterans and to develop more effective treatment services that better address comorbid issues commonly experienced by rural smokers.
- Trial name
- NCT01592695
- Testing
- Nicotine replacement therapy - transdermal nicotine patch, Tailored behavioral intervention, Tobacco quit line referral
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Nicotine Dependence, Substance Use Disorders
Healthy People Initiative (HPI)
Addictions do not occur in isolation. Tackling addictions requires addressing social determinants such as isolation, homelessness, marginalization, and unemployment.
- Trial name
- HPI (NCT03506867)
- Testing
- Life skills, training, education and work/volunteer opportunities, Usual Care
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Nicotine Dependence
Community-based Smoking Cessation Treatment for Adults With High Stress Sensitivity.
Anxiety sensitivity, reflecting the fear of bodily sensations, is a risk factor for the maintenance and relapse of smoking. This study is designed to address the question - is a smoking cessation intervention personalized to high…
- Trial name
- STEP3 (NCT06053567)
- Testing
- Aerobic Exercise, Counseling, Nicotine patch
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
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